Jung, Steffen

ATP mediates rapid microglial response to local brain injury in vivo

Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAdenosine and Purinergic Signaling

Cited by 3,913

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 3,245

Development of Monocytes, Macrophages, and Dendritic Cells

Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010) · Science

Immune cells in cancerImmunotherapy and Immune Responses

Cited by 3,049

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology

Chemokine receptors and signalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 2,632

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

Lavin, Y., Winter, D., Blecher-Gonen, R., David, E., Keren-Shaul, H., Merad, M., Jung, S., & Amit, I. (2014) · Cell

Genomics and Chromatin DynamicsImmune cells in cancer

Cited by 2,167

Microglia states and nomenclature: A field at its crossroads

Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., et al. (2022) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,973

Monocytes and macrophages: developmental pathways and tissue homeostasis

Ginhoux, F., & Jung, S. (2014) · Nature Reviews Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,840

Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types

Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Elefant, N., Paul, F., Zaretsky, I., Mildner, A., Cohen, N., Jung, S., Tanay, A., et al. (2014) · Science

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,795

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

Rothhammer, V., Mascanfroni, I. D., Bunse, L., Takenaka, M. C., Kenison, J. E., Mayo, L., Chao, C.-C., Patel, B., Yan, R., Blain, M., et al. (2016) · Nature Medicine

Tryptophan and brain disordersinterferon and immune responses

Cited by 1,559

Control of microglial neurotoxicity by the fractalkine receptor

Cardona, A. E., Pioro, E. P., Sasse, M. E., Kostenko, V., Cardona, S. M., Dijkstra, I. M., Huang, D., Kidd, G., Dombrowski, S., Dutta, R., et al. (2006) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 1,531

Microglia Biology: One Century of Evolving Concepts

Prinz, M., Jung, S., & Priller, J. (2019) · Cell

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,525

Origin, fate and dynamics of macrophages at central nervous system interfaces

Goldmann, T., Wieghofer, P., Jordão, M. J. C., Prutek, F., Hagemeyer, N., Frenzel, K., Amann, L., Staszewski, O., Kierdorf, K., Krueger, M., et al. (2016) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,209

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

Paul, F., Arkin, Y., Giladi, A., Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., et al. (2015) · Cell

Single-cell and spatial transcriptomicsHematopoietic Stem Cell Transplantation

Cited by 1,082

Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge

Shemer, A., Grozovski, J., Tay, T. L., Tao, J., Volaski, A., Süß, P., Ardura-Fabregat, A., Gross-Vered, M., Kim, J.-S., David, E., et al. (2018) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsHematopoietic Stem Cell Transplantation

Cited by 1,052

Macrophages: Development and Tissue Specialization

Varol, C., Mildner, A., & Jung, S. (2015) · Annual Review of Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 962

Chromatin state dynamics during blood formation

Lara-Astiaso, D., Weiner, A., Lorenzo-Vivas, E., Zaretsky, I., Jaitin, D. A., David, E., Keren-Shaul, H., Mildner, A., Winter, D., Jung, S., et al. (2014) · Science

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 776

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

Shechter, R., London, A., Varol, C., Raposo, C., Cusimano, M., Yovel, G., Rolls, A., Mack, M., Pluchino, S., Martino, G., et al. (2009) · PLoS Medicine

Spinal Cord Injury ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 770

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

Goldmann, T., Wieghofer, P., Müller, P. F., Wolf, Y., Varol, D., Yona, S., Brendecke, S. M., Kierdorf, K., Staszewski, O., Datta, M., et al. (2013) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 688

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

Shechter, R., Miller, O., Yovel, G., Rosenzweig, N., London, A., Ruckh, J., Kim, K.-W., Klein, E., Kalchenko, V., Bendel, P., et al. (2013) · Immunity

Spinal Cord Injury ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 683

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

Bruttger, J., Karram, K., Wörtge, S., Regen, T., Marini, F., Hoppmann, N., Klein, M., Blank, T., Yona, S., Wolf, Y., et al. (2015) · Immunity

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 634

Monocytes give rise to mucosal, but not splenic, conventional dendritic cells

Varol, C., Landsman, L., Fogg, D. K., Greenshtein, L., Gildor, B., Margalit, R., Kalchenko, V., Geissmann, F., & Jung, S. (2007) · The Journal of Experimental Medicine

Immunotherapy and Immune ResponsesImmune cells in cancer

Cited by 627

Age-related myelin degradation burdens the clearance function of microglia during aging

Safaiyan, S., Kannaiyan, N., Snaidero, N., Brioschi, S., Biber, K., Yona, S., Edinger, A. L., Jung, S., Rossner, M. J., & Simons, M. (2016) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 604

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

Tay, T. L., Mai, D., Dautzenberg, J., Fernández-Klett, F., Lin, G., Sagar, Datta, M., Drougard, A., Stempfl, T., Ardura-Fabregat, A., et al. (2017) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 597

Distinct Differentiation Potential of Blood Monocyte Subsets in the Lung

Landsman, L., Varol, C., & Jung, S. (2007) · The Journal of Immunology

Immune cells in cancerAtherosclerosis and Cardiovascular Diseases

Cited by 322