Zarate, Carlos A.

Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R )-hydroxynorketamine

Highland, J. N., Morris, P. J., Zanos, P., Lovett, J., Ghosh, S., Wang, A. Q., Zarate, C. A., Thomas, C. J., Moaddel, R., & Gould, T. D. (2019) · Journal of Psychopharmacology

Treatment of Major DepressionPharmacogenetics and Drug Metabolism

Cited by 62

Ketamine regulates the presynaptic release machinery in the hippocampus

Müller, H. K., Wegener, G., Liebenberg, N., Zarate, C. A., Popoli, M., & Elfving, B. (2013) · Journal of Psychiatric Research

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 61

BDNF plasma levels after antidepressant treatment with sertraline and transcranial direct current stimulation: Results from a factorial, randomized, sham-controlled trial

Brunoni, A. R., Machado-Vieira, R., Zarate, C. A., Vieira, E. L. M., Vanderhasselt, M.-A., Nitsche, M. A., Valiengo, L., Benseñor, I. M., Lotufo, P. A., Gattaz, W. F., et al. (2014) · European Neuropsychopharmacology

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 60

Brain inflammation co-localizes highly with tau in mild cognitive impairment due to early-onset Alzheimer’s disease

Appleton, J., Finn, Q., Zanotti-Fregonara, P., Yu, M., Faridar, A., Nakawah, M. O., Zarate, C., Carrillo, M. C., Dickerson, B. C., Rabinovici, G. D., et al. (2025) · Brain

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 58

Ketamine-Induced Glutamatergic Mechanisms of Sleep and Wakefulness: Insights for Developing Novel Treatments for Disturbed Sleep and Mood

Duncan, W. C., Ballard, E. D., & Zarate, C. A. (2017) · Handbook of Experimental Pharmacology

Treatment of Major DepressionSleep and Wakefulness Research

Cited by 58

Effects of Ketamine on Brain Activity During Emotional Processing: Differential Findings in Depressed Versus Healthy Control Participants

Reed, J. L., Nugent, A. C., Furey, M. L., Szczepanik, J. E., Evans, J. W., & Zarate, C. A. (2019) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 56

Pharmacologic Treatment of Dimensional Anxious Depression: A Review

Ionescu, D. F., Niciu, M. J., Richards, E. M., & Zarate, C. A. (2014) · The Primary Care Companion For CNS Disorders

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 56

Evaluating global brain connectivity as an imaging marker for depression: influence of preprocessing strategies and placebo-controlled ketamine treatment

Kraus, C., Mkrtchian, A., Kadriu, B., Nugent, A. C., Zarate, C. A., & Evans, J. W. (2020) · Neuropsychopharmacology

Functional Brain Connectivity StudiesTreatment of Major Depression

Cited by 54

Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials

Saelens, J., Gramser, A., Watzal, V., Zarate, C. A., Lanzenberger, R., & Kraus, C. (2025) · Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 51

Brain-based correlates of antidepressant response to ketamine: a comprehensive systematic review of neuroimaging studies

Medeiros, G. C., Matheson, M., Demo, I., Reid, M. J., Matheson, S., Twose, C., Smith, G. S., Gould, T. D., Zarate, C. A., Barrett, F. S., et al. (2023) · The Lancet Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 49

Timing is everything: does the robust upregulation of noradrenergically regulated plasticity genes underlie the rapid antidepressant effects of sleep deprivation?

Payne, J. L., Quiroz, J. A., Zarate, C. A., & Manji, H. K. (2002) · Biological Psychiatry

Treatment of Major DepressionSleep and Wakefulness Research

Cited by 46

Developing biomarkers in mood disorders research through the use of rapid-acting antidepressants

Niciu, M. J., Mathews, D. C., Nugent, A. C., Ionescu, D. F., Furey, M. L., Richards, E. M., Machado-Vieira, R., & Zarate, C. A. (2014) · Depression and Anxiety

Treatment of Major DepressionBipolar Disorder and Treatment

Cited by 45

Neurobiological aspects of suicide and suicide attempts in bipolar disorder

Mathews, D., Richards, E., Niciu, M., Ionescu, D., Rasimas, J., & Zarate, C. (2013) · Translational Neuroscience

Bipolar Disorder and TreatmentSuicide and Self-Harm Studies

Cited by 39

A predictive coding framework for understanding major depression

Gilbert, J. R., Wusinich, C., & Zarate, C. A. (2022) · Frontiers in Human Neuroscience

Neural and Behavioral Psychology StudiesTreatment of Major Depression

Cited by 38

Multilayer MEG functional connectivity as a potential marker for suicidal thoughts in major depressive disorder

Nugent, A. C., Ballard, E. D., Gilbert, J. R., Tewarie, P. K., Brookes, M. J., & Zarate, C. A. (2020) · NeuroImage: Clinical

Functional Brain Connectivity StudiesTreatment of Major Depression

Cited by 34

Translating the immediate effects of S-Ketamine using hippocampal subfield analysis in healthy subjects-results of a randomized controlled trial

Höflich, A., Kraus, C., Pfeiffer, R. M., Seiger, R., Rujescu, D., Zarate, C. A., Kasper, S., Winkler, D., & Lanzenberger, R. (2021) · Translational Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 34

Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt

Ballard, E. D., Ionescu, D. F., Voort, J. L. V., Slonena, E. E., Franco-Chaves, J. A., Zarate, C. A., & Grillon, C. (2014) · Journal of Affective Disorders

Suicide and Self-Harm StudiesAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 33

Irremediability in psychiatric euthanasia: examining the objective standard

Nicolini, M. E., Jardas, E., Zarate, C. A., Gastmans, C., & Kim, S. Y. H. (2023) · Psychological Medicine

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 31

Magnetoencephalographic correlates of suicidal ideation in major depression

Gilbert, J. R., Ballard, E. D., Galiano, C. S., Nugent, A. C., & Zarate, C. A. (2020) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Treatment of Major DepressionSuicide and Self-Harm Studies

Cited by 28

Ketamine Mechanism of Action: Separating the Wheat from the Chaff

Gould, T. D., Zanos, P., & Zarate, C. A. (2017) · Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 24

Treatment of depression with ketamine does not change plasma levels of brain-derived neurotrophic factor or vascular endothelial growth factor

Medeiros, G. C., Greenstein, D., Kadriu, B., Yuan, P., Park, L. T., Gould, T. D., & Zarate, C. A. (2021) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 24

Functional imaging of the implicit association of the self with life and death

Ballard, E. D., Reed, J. L., Szczepanik, J., Evans, J. W., Yarrington, J. S., Dickstein, D. P., Nock, M. K., Nugent, A. C., & Zarate, C. A. (2019) · Suicide and Life-Threatening Behavior

Suicide and Self-Harm StudiesDeath Anxiety and Social Exclusion

Cited by 22

Evaluation of the Safety, Tolerability, and Pharmacokinetic Profiles of TP0473292 (TS-161), A Prodrug of a Novel Orthosteric mGlu2/3 Receptor Antagonist TP0178894, in Healthy Subjects and Its Antidepressant-Like Effects in Rodents

Watanabe, M., Marcy, B., Hiroki, A., Watase, H., Kinoshita, K., Iijima, M., Marumo, T., Zarate, C. A., & Chaki, S. (2022) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 22

Network changes in insula and amygdala connectivity accompany implicit suicidal associations

Ballard, E. D., Gilbert, J. R., Fields, J. S., Nugent, A. C., & Zarate, C. A. (2020) · Frontiers in Psychiatry

Suicide and Self-Harm StudiesFunctional Brain Connectivity Studies

Cited by 20