Zarate, Carlos A.

Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders

Merikangas, K. R., Cui, L., Heaton, L., Nakamura, E., Roca, C., Ding, J., Qin, H., Guo, W., Yao-Shugart, Y., Zarate, C., et al. (2014) · Molecular Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 166

Glutamatergic Neurotransmission: Pathway to Developing Novel Rapid-Acting Antidepressant Treatments

Kadriu, B., Musazzi, L., Henter, I. D., Graves, M., Popoli, M., & Zarate, C. A. (2019) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 165

Clinical Predictors of Ketamine Response in Treatment-Resistant Major Depression

Niciu, M. J., Luckenbaugh, D. A., Ionescu, D. F., Guevara, S., Machado-Vieira, R., Richards, E. M., Brutsche, N. E., Nolan, N. M., & Zarate, C. A. (2014) · The Journal of Clinical Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 165

What is the optimal serum level for lithium in the maintenance treatment of bipolar disorder? A systematic review and recommendations from the ISBD/IGSLI Task Force on treatment with lithium

Nolen, W. A., Licht, R. W., Young, A. H., Malhi, G. S., Tohen, M., Vieta, E., Kupka, R. W., Zarate, C., Nielsen, R. E., Baldessarini, R. J., et al. (2019) · Bipolar Disorders

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 164

Ketamine Treatment for Depression: A Review

Yavi, M., Lee, H., Henter, I. D., Park, L. T., & Zarate, C. A. (2022) · Discover Mental Health

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 161

Antidepressant-relevant concentrations of the ketamine metabolite (2 R ,6 R )-hydroxynorketamine do not block NMDA receptor function

Lumsden, E. W., Troppoli, T. A., Myers, S. J., Zanos, P., Aracava, Y., Kehr, J., Lovett, J., Kim, S., Wang, F.-H., Schmidt, S., et al. (2019) · Proceedings of the National Academy of Sciences

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 158

McLean-Harvard International First-Episode Project: Two-Year Stability of DSM-IV Diagnoses in 500 First-Episode Psychotic Disorder Patients

Salvatore, P., Baldessarini, R. J., Tohen, M., Khalsa, H.-M. K., Sanchez-Toledo, J. P., Zarate, C. A., Vieta, E., & Maggini, C. (2009) · The Journal of Clinical Psychiatry

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 155

Brain-Derived Neurotrophic Factor and Initial Antidepressant Response to an N-Methyl-D-Aspartate Antagonist

Machado-Vieira, R., Yuan, P., Brutsche, N., DiazGranados, N., Luckenbaugh, D., Manji, H. K., & Zarate, C. A. (2009) · The Journal of Clinical Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 155

( 2R,6R )-hydroxynorketamine exerts mGlu 2 receptor-dependent antidepressant actions

Zanos, P., Highland, J. N., Stewart, B. W., Georgiou, P., Jenne, C. E., Lovett, J., Morris, P. J., Thomas, C. J., Moaddel, R., Zarate, C. A., et al. (2019) · Proceedings of the National Academy of Sciences

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 152

Antidepressant actions of ketamine: from molecular mechanisms to clinical practice

Monteggia, L. M., & Zarate, C. (2015) · Current Opinion in Neurobiology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 149

Lithium treatment of bipolar disorder in adults: a systematic review of randomized trials and meta-analyses

Fountoulakis, K. N., Tohen, M., & Zarate, C. A. (2022) · European Neuropsychopharmacology

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 146

Double-Blind Comparison of the Continued Use of Antipsychotic Treatment Versus Its Discontinuation in Remitted Manic Patients

Zarate, C. A., & Tohen, M. (2004) · American Journal of Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 144

Novel Glutamatergic Modulators for the Treatment of Mood Disorders: Current Status

Henter, I. D., Park, L. T., & Zarate, C. A. (2021) · CNS Drugs

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 142

Molecular Pharmacology and Neurobiology of Rapid-Acting Antidepressants

Gould, T. D., Zarate, C. A., & Thompson, S. M. (2019) · Annual Review of Pharmacology and Toxicology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 133

Ketamine and Beyond: Investigations into the Potential of Glutamatergic Agents to Treat Depression

Lener, M. S., Kadriu, B., & Zarate, C. A. (2017) · Drugs

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 131

Protein Kinase C Inhibitors: Rationale for Use and Potential in the Treatment of Bipolar Disorder

Zarate, C. A., & Manji, H. K. (2009) · CNS Drugs

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 122

A review of factors associated with greater likelihood of suicide attempts and suicide deaths in bipolar disorder: Part II of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder

Schaffer, A., Isometsä, E. T., Azorin, J.-M., Cassidy, F., Goldstein, T., Rihmer, Z., Sinyor, M., Tondo, L., Moreno, D. H., Turecki, G., et al. (2015) · Australian & New Zealand Journal of Psychiatry

Bipolar Disorder and TreatmentSuicide and Self-Harm Studies

Cited by 120

Defining anxious depression: a review of the literature

Ionescu, D. F., Niciu, M. J., Henter, I. D., & Zarate, C. A. (2013) · CNS Spectrums

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

Cited by 119

NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine

Zanos, P., Brown, K. A., Georgiou, P., Yuan, P., Zarate, C. A., Thompson, S. M., & Gould, T. D. (2023) · The Journal of Neuroscience

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 115

Comprehensive assessment of side effects associated with a single dose of ketamine in treatment-resistant depression

Acevedo-Diaz, E. E., Cavanaugh, G. W., Greenstein, D., Kraus, C., Kadriu, B., Zarate, C. A., & Park, L. T. (2020) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 113

Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk

Tohen, M. F., Castillo, J., Baldessarini, R. J., Zarate, C. A., & Kando, J. C. (1995) · American Journal of Psychiatry

Drug-Induced Adverse ReactionsPharmacovigilance and Adverse Drug Reactions

Cited by 112

Effect of Baseline Anxious Depression on Initial and Sustained Antidepressant Response to Ketamine

Ionescu, D. F., Luckenbaugh, D. A., Niciu, M. J., Richards, E. M., Slonena, E. E., Vande Voort, J. L., Brutsche, N. E., & Zarate, C. A. (2014) · The Journal of Clinical Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 111

Ketamine modulates fronto-striatal circuitry in depressed and healthy individuals

Mkrtchian, A., Evans, J. W., Kraus, C., Yuan, P., Kadriu, B., Nugent, A. C., Roiser, J. P., & Zarate, C. A. (2021) · Molecular Psychiatry

Treatment of Major DepressionTranscranial Magnetic Stimulation Studies

Cited by 110

Ketamine in neuropsychiatric disorders: an update

Johnston, J. N., Kadriu, B., Kraus, C., Henter, I. D., & Zarate, C. A. (2024) · Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 108