Hagerman, Randi J.

Fragile X syndrome

Hagerman, R. J., Berry-Kravis, E., Hazlett, H. C., Bailey, D. B., Moine, H., Kooy, R. F., Tassone, F., Gantois, I., Sonenberg, N., Mandel, J. L., et al. (2017) · Nature Reviews Disease Primers

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 838

Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

Jacquemont, S., Curie, A., des Portes, V., Torrioli, M. G., Berry-Kravis, E., Hagerman, R. J., Ramos, F. J., Cornish, K., He, Y., Paulding, C., et al. (2011) · Science Translational Medicine

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 609

Advances in the Treatment of Fragile X Syndrome

Hagerman, R. J., Berry-Kravis, E., Kaufmann, W. E., Ono, M. Y., Tartaglia, N., Lachiewicz, A., Kronk, R., Delahunty, C., Hessl, D., Visootsak, J., et al. (2009) · Pediatrics

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 596

The Gut Microbiota and Autism Spectrum Disorders

Li, Q., Han, Y., Dy, A. B. C., & Hagerman, R. J. (2017) · Frontiers in Cellular Neuroscience

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 462

A pilot open label, single dose trial of fenobam in adults with fragile X syndrome

Berry-Kravis, E., Hessl, D., Coffey, S., Hervey, C., Schneider, A., Yuhas, J., Hutchison, J., Snape, M., Tranfaglia, M., Nguyen, D. V., et al. (2009) · Journal of Medical Genetics

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 411

Autism Profiles of Males With Fragile X Syndrome

Harris, S. W., Hessl, D., Goodlin-Jones, B., Ferranti, J., Bacalman, S., Barbato, I., Tassone, F., Hagerman, P. J., Herman, K., & Hagerman, R. J. (2008) · American Journal on Mental Retardation

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 396

Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome

Berry-Kravis, E. M., Lindemann, L., Jønch, A. E., Apostol, G., Bear, M. F., Carpenter, R. L., Crawley, J. N., Curie, A., Des Portes, V., Hossain, F., et al. (2018) · Nature Reviews Drug Discovery

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 336

Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial

Berry-Kravis, E. M., Hessl, D., Rathmell, B., Zarevics, P., Cherubini, M., Walton-Bowen, K., Mu, Y., Nguyen, D. V., Gonzalez-Heydrich, J., Wang, P. P., et al. (2012) · Science Translational Medicine

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 328

Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder in Boys with the Fragile X Premutation

FARZIN, F., PERRY, H., HESSL, D., LOESCH, D., COHEN, J., BACALMAN, S., GANE, L., TASSONE, F., HAGERMAN, P., & HAGERMAN, R. (2006) · Journal of Developmental & Behavioral Pediatrics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 325

Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics

Bagni, C., Tassone, F., Neri, G., & Hagerman, R. (2012) · Journal of Clinical Investigation

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 321

Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization

Cordeiro, L., Ballinger, E., Hagerman, R., & Hessl, D. (2011) · Journal of Neurodevelopmental Disorders

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 316

Fragile X Syndrome

Hagerman, R. J. (2002) · Johns Hopkins University Press eBooks

Genetics and Neurodevelopmental DisordersDown syndrome and intellectual disability research

Cited by 299

A Randomized Double-Blind, Placebo-Controlled Trial of Minocycline in Children and Adolescents with Fragile X Syndrome

Leigh, M. J. S., Nguyen, D. V., Mu, Y., Winarni, T. I., Schneider, A., Chechi, T., Polussa, J., Doucet, P., Tassone, F., Rivera, S. M., et al. (2013) · Journal of Developmental & Behavioral Pediatrics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 298

Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials

Berry-Kravis, E., Des Portes, V., Hagerman, R., Jacquemont, S., Charles, P., Visootsak, J., Brinkman, M., Rerat, K., Koumaras, B., Zhu, L., et al. (2016) · Science Translational Medicine

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 270

Fragile X and autism: intertwined at the molecular level leading to targeted treatments

Hagerman, R., Hoem, G., & Hagerman, P. (2010) · Molecular Autism

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 247

An analysis of autism in fifty males with the fragile X syndrome

Hagerman, R. J., Jackson, A. W., Levitas, A., Rimland, B., Braden, M., Opitz, J. M., & Reynolds, J. F. (1986) · American Journal of Medical Genetics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 238

An Update on Psychopharmacological Treatment of Autism Spectrum Disorder

Aishworiya, R., Valica, T., Hagerman, R., & Restrepo, B. (2022) · Neurotherapeutics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 233

Fragile X-Associated Neuropsychiatric Disorders (FXAND)

Hagerman, R. J., Protic, D., Rajaratnam, A., Salcedo-Arellano, M. J., Aydin, E. Y., & Schneider, A. (2018) · Frontiers in Psychiatry

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 204

Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome

Hoeffer, C. A., Sanchez, E., Hagerman, R. J., Mu, Y., Nguyen, D. V., Wong, H., Whelan, A. M., Zukin, R. S., Klann, E., & Tassone, F. (2012) · Genes, Brain and Behavior

Genetics and Neurodevelopmental DisordersRNA and protein synthesis mechanisms

Cited by 198

Fragile X spectrum disorders

Lozano, R., Rosero, C. A., & Hagerman, R. J. (2014) · Intractable & Rare Diseases Research

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 186

Arbaclofen in fragile X syndrome: results of phase 3 trials

Berry-Kravis, E., Hagerman, R., Visootsak, J., Budimirovic, D., Kaufmann, W. E., Cherubini, M., Zarevics, P., Walton-Bowen, K., Wang, P., Bear, M. F., et al. (2017) · Journal of Neurodevelopmental Disorders

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 183

A solution to limitations of cognitive testing in children with intellectual disabilities: the case of fragile X syndrome

Hessl, D., Nguyen, D. V., Green, C., Chavez, A., Tassone, F., Hagerman, R. J., Senturk, D., Schneider, A., Lightbody, A., Reiss, A. L., et al. (2009) · Journal of Neurodevelopmental Disorders

Genetics and Neurodevelopmental DisordersDown syndrome and intellectual disability research

Cited by 182

AGG interruptions within the maternal FMR1 gene reduce the risk of offspring with fragile X syndrome

Yrigollen, C. M., Durbin-Johnson, B., Gane, L., Nelson, D. L., Hagerman, R., Hagerman, P. J., & Tassone, F. (2012) · Genetics in Medicine

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 179

Fragile X: Leading the Way for Targeted Treatments in Autism

Wang, L. W., Berry-Kravis, E., & Hagerman, R. J. (2010) · Neurotherapeutics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 176