Krijgsveld, Jeroen

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

Castello, A., Fischer, B., Eichelbaum, K., Horos, R., Beckmann, B. M., Strein, C., Davey, N. E., Humphreys, D. T., Preiss, T., Steinmetz, L. M., et al. (2012) · Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 2,132

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

Haas, S., Hansson, J., Klimmeck, D., Loeffler, D., Velten, L., Uckelmann, H., Wurzer, S., Prendergast, Á. M., Schnell, A., Hexel, K., et al. (2015) · Cell Stem Cell

Platelet Disorders and TreatmentsHematopoietic Stem Cell Transplantation

Cited by 471

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

Morinière, J., Rousseaux, S., Steuerwald, U., Soler-López, M., Curtet, S., Vitte, A.-L., Govin, J., Gaucher, J., Sadoul, K., Hart, D. J., et al. (2009) · Nature

Genomics and Chromatin DynamicsProtein Degradation and Inhibitors

Cited by 469

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

Raffel, S., Falcone, M., Kneisel, N., Hansson, J., Wang, W., Lutz, C., Bullinger, L., Poschet, G., Nonnenmacher, Y., Barnert, A., et al. (2017) · Nature

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 354

Selective enrichment of newly synthesized proteins for quantitative secretome analysis

Eichelbaum, K., Winter, M., Diaz, M. B., Herzig, S., & Krijgsveld, J. (2012) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 248

Quantitative Proteomics by Metabolic Labeling of Model Organisms

Gouw, J. W., Krijgsveld, J., & Heck, A. J. R. (2010) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 151

Exosomal Secretion of Cytoplasmic Prostate Cancer Xenograft-derived Proteins

Jansen, F. H., Krijgsveld, J., van Rijswijk, A., van den Bemd, G.-J., van den Berg, M. S., van Weerden, W. M., Willemsen, R., Dekker, L. J., Luider, T. M., & Jenster, G. (2009) · Molecular & Cellular Proteomics

Extracellular vesicles in diseaseAdvanced Proteomics Techniques and Applications

Cited by 107

DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts

Goyal, A., Bauer, J., Hey, J., Papageorgiou, D. N., Stepanova, E., Daskalakis, M., Scheid, J., Dubbelaar, M., Klimovich, B., Schwarz, D., et al. (2023) · Nature Communications

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 102

Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis

Singhal, M., Gengenbacher, N., Abdul Pari, A. A., Kamiyama, M., Hai, L., Kuhn, B. J., Kallenberg, D. M., Kulkarni, S. R., Camilli, C., Preuß, S. F., et al. (2021) · Science Translational Medicine

Angiogenesis and VEGF in CancerCancer Cells and Metastasis

Cited by 80

Novel Hsp90 partners discovered using complementary proteomic approaches

Tsaytler, P. A., Krijgsveld, J., Goerdayal, S. S., Rüdiger, S., & Egmond, M. R. (2009) · Cell Stress and Chaperones

Heat shock proteins researchUbiquitin and proteasome pathways

Cited by 46

Suppression of Mediator is regulated by Cdk8-dependent Grr1 turnover of the Med3 coactivator

Gonzalez, D., Hamidi, N., Del Sol, R., Benschop, J. J., Nancy, T., Li, C., Francis, L., Tzouros, M., Krijgsveld, J., Holstege, F. C. P., et al. (2014) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 43

MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention

Weigel, B., Tegethoff, J. F., Grieder, S. D., Lim, B., Nagarajan, B., Liu, Y.-C., Truberg, J., Papageorgiou, D., Adrian-Segarra, J. M., Schmidt, L. K., et al. (2023) · Molecular Psychiatry

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 31

Degradome analysis to identify direct protein substrates of small-molecule degraders

Jochem, M., Schrempf, A., Wagner, L.-M., Cisneros, J., Ng, A., Winter, G. E., & Krijgsveld, J. (2024) · Cell chemical biology

Protein Degradation and InhibitorsAdvanced Proteomics Techniques and Applications

Cited by 25

Degradome analysis to identify direct protein substrates of small-molecule degraders

Jochem, M., Schrempf, A., Wagner, L.-M., Segal, D., Cisneros, J., Ng, A., Winter, G. E., & Krijgsveld, J. (2025) · Cell Chemical Biology

Protein Degradation and InhibitorsAdvanced Proteomics Techniques and Applications

Cited by 25

An integrated workflow for quantitative analysis of the newly synthesized proteome

Borteçen, T., Müller, T., & Krijgsveld, J. (2023) · Nature Communications

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 19

Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells

Delacher, M., Barra, M. M., Herzig, Y., Eichelbaum, K., Rafiee, M.-R., Richards, D. M., Träger, U., Hofer, A.-C., Kazakov, A., Braband, K. L., et al. (2020) · iScience

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 11