Vandenabeele, Peter

Dual Signaling of the Fas Receptor: Initiation of Both Apoptotic and Necrotic Cell Death Pathways

Vercammen, D., Brouckaert, G., Denecker, G., Van de Craen, M., Declercq, W., Fiers, W., & Vandenabeele, P. (1998) · The Journal of Experimental Medicine

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 556

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

Vandenabeele, P., Declercq, W., Van Herreweghe, F., & Vanden Berghe, T. (2010) · Science Signaling

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 482

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

Takahashi, N., Duprez, L., Grootjans, S., Cauwels, A., Nerinckx, W., DuHadaway, J. B., Goossens, V, Roelandt, R., Van Hauwermeiren, F., Libert, C., et al. (2012) · Cell Death & Disease

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 465

NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling

Dondelinger, Y., Jouan-Lanhouet, S., Divert, T., Theatre, E., Bertin, J., Gough, P. J., Giansanti, P., Heck, A. J. R., Dejardin, E., Vandenabeele, P., et al. (2015) · Molecular Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 431

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation

Jouan-Lanhouet, S., Arshad, M. I., Piquet-Pellorce, C., Martin-Chouly, C., Le Moigne-Muller, G., Van Herreweghe, F., Takahashi, N., Sergent, O., Lagadic-Gossmann, D., Vandenabeele, P., et al. (2012) · Cell Death & Differentiation

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 357

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

Vanlangenakker, N., Vanden Berghe, T., Bogaert, P., Laukens, B., Zobel, K., Deshayes, K., Vucic, D., Fulda, S., Vandenabeele, P., & Bertrand, M. J. M. (2011) · Cell Death & Differentiation

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 339

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

Takahashi, N., Vereecke, L., Bertrand, M. J. M., Duprez, L., Berger, S. B., Divert, T., Gonçalves, A., Sze, M., Gilbert, B., Kourula, S., et al. (2014) · Nature

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 318

Clearance of apoptotic and necrotic cells and its immunological consequences

Krysko, D. V., D’Herde, K., & Vandenabeele, P. (2006) · Apoptosis

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 316

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

Dondelinger, Y., Aguileta, M. A., Goossens, V, Dubuisson, C., Grootjans, S., Dejardin, E., Vandenabeele, P., & Bertrand, M. J. M. (2013) · Cell Death & Differentiation

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 312

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

Garg, A. D., Dudek, A. M., Ferreira, G. B., Verfaillie, T., Vandenabeele, P., Krysko, D. V., Mathieu, C., & Agostinis, P. (2013) · Autophagy

Autophagy in Disease and TherapyPhotodynamic Therapy Research Studies

Cited by 305

Caspase-14 protects against epidermal UVB photodamage and water loss

Denecker, G., Hoste, E., Gilbert, B., Hochepied, T., Ovaere, P., Lippens, S., Van den Broecke, C., Van Damme, P., D'Herde, K., Hachem, J.-P., et al. (2007) · Nature Cell Biology

Skin and Cellular Biology ResearchSkin Protection and Aging

Cited by 298

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

Tucci, P., Agostini, M., Grespi, F., Markert, E. K., Terrinoni, A., Vousden, K. H., Muller, P. A. J., Dötsch, V., Kehrloesser, S., Sayan, B. S., et al. (2012) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationProstate Cancer Treatment and Research

Cited by 286

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Canli, Ö., Alankuş, Y. B., Grootjans, S., Vegi, N., Hültner, L., Hoppe, P. S., Schroeder, T., Vandenabeele, P., Bornkamm, G. W., & Greten, F. R. (2016) · Blood

Cell death mechanisms and regulationRedox biology and oxidative stress

Cited by 247

Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing

Lippens, S., Kockx, M., Knaapen, M., Mortier, L., Polakowska, R., Verheyen, A., Garmyn, M., Zwijsen, A., Formstecher, P., Huylebroeck, D., et al. (2000) · Cell Death & Differentiation

Cell death mechanisms and regulationSkin and Cellular Biology Research

Cited by 245

Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

Roberti, M. P., Yonekura, S., Duong, C. P. M., Picard, M., Ferrere, G., Tidjani Alou, M., Rauber, C., Iebba, V., Lehmann, C. H. K., Amon, L., et al. (2020) · Nature Medicine

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 208

When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157

Rojas-Rivera, D., Delvaeye, T., Roelandt, R., Nerinckx, W., Augustyns, K., Vandenabeele, P., & Bertrand, M. J. M. (2017) · Cell Death & Differentiation

Cell death mechanisms and regulationEndoplasmic Reticulum Stress and Disease

Cited by 206

Targeting ferroptosis protects against experimental (multi)organ dysfunction and death

Van Coillie, S., Van San, E., Goetschalckx, I., Wiernicki, B., Mukhopadhyay, B., Tonnus, W., Choi, S. M., Roelandt, R., Dumitrascu, C., Lamberts, L., et al. (2022) · Nature Communications

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 186

Targeting ferroptosis protects against multiorgan dysfunction and death.

VandenBerghe, T., Coillie, S. V., Goetschalckx, I., Wiernicki, B., Mukhopadhyay, B., Tonnus, W., San, E. V., Choi, S. M., Roelandt, R., Dumitrascu, C., et al. (2021) · Nature Communications

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 186

CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3

Seo, J., Lee, E.-W., Sung, H., Seong, D., Dondelinger, Y., Shin, J., Jeong, M., Lee, H.-K., Kim, J.-H., Han, S. Y., et al. (2016) · Nature Cell Biology

Cell death mechanisms and regulationUbiquitin and proteasome pathways

Cited by 182

Simultaneous Targeting of IL-1 and IL-18 Is Required for Protection against Inflammatory and Septic Shock

Berghe, T. V., Demon, D., Bogaert, P., Vandendriessche, B., Goethals, A., Depuydt, B., Vuylsteke, M., Roelandt, R., Van Wonterghem, E., Vandenbroecke, J., et al. (2014) · American Journal of Respiratory and Critical Care Medicine

Sepsis Diagnosis and TreatmentInflammasome and immune disorders

Cited by 173

An evolutionary perspective on the necroptotic pathway

Dondelinger, Y., Hulpiau, P., Saeys, Y., Bertrand, M. J. M., & Vandenabeele, P. (2016) · Trends in Cell Biology

Cell death mechanisms and regulationImmune Response and Inflammation

Cited by 159

Punching Holes in Cellular Membranes: Biology and Evolution of Gasdermins

De Schutter, E., Roelandt, R., Riquet, F. B., Van Camp, G., Wullaert, A., & Vandenabeele, P. (2021) · Trends in Cell Biology

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 158

TUMOUR NECROSIS FACTOR-INDUCED NECROSIS VERSUS ANTI-Fas-INDUCED APOPTOSIS IN L929 CELLS

Vercammen, D., Vandenabeele, P., Beyaert, R., Declercq, W., & Fiers, W. (1997) · Cytokine

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 157

The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis

Günther, C., He, G.-W., Kremer, A. E., Murphy, J. M., Petrie, E. J., Amann, K., Vandenabeele, P., Linkermann, A., Poremba, C., Schleicher, U., et al. (2016) · Journal of Clinical Investigation

Cell death mechanisms and regulationLiver Diseases and Immunity

Cited by 157