Howley, Peter M.

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J., & Howley, P. M. (1990) · Cell

Cancer-related Molecular PathwaysCervical Cancer and HPV Research

Cited by 3,995

The human papilloma virus-16 E7-oncoprotein is able to bind to the retinoblastoma gene product

Dyson, N., Howley, P. M., Münger, K., & Harlow, E. (1989) · Science

Cervical Cancer and HPV ResearchCancer-related Molecular Pathways

Cited by 3,017

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

Werness, B. A., Levine, A. J., & Howley, P. M. (1990) · Science

Cervical Cancer and HPV ResearchCancer-related Molecular Pathways

Cited by 2,562

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.

Huibregtse, J. M., Scheffner, M., & Howley, P. M. (1991) · The EMBO Journal

Cancer-related Molecular PathwaysCervical Cancer and HPV Research

Cited by 879

Virus Infection Induces the Assembly of Coordinately Activated Transcription Factors on the IFN-β Enhancer In Vivo

Wathelet, M. G., Lin, C. H., Parekh, B. S., Ronco, L. V., Howley, P. M., & Maniatis, T. (1998) · Molecular Cell

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 730

The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3

Rahman, S., Sowa, M. E., Ottinger, M., Smith, J. A., Shi, Y., Harper, J. W., & Howley, P. M. (2011) · Molecular and Cellular Biology

Protein Degradation and InhibitorsGenomics and Chromatin Dynamics

Cited by 532

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

Grossman, S. R., Perez, M., Kung, A. L., Joseph, M., Mansur, C., Xiao, Z.-X., Kumar, S., Howley, P. M., & Livingston, D. M. (1998) · Molecular Cell

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 414

Comprehensive Analysis of Host Cellular Interactions with Human Papillomavirus E6 Proteins Identifies New E6 Binding Partners and Reflects Viral Diversity

White, E. A., Kramer, R. E., Tan, M. J. A., Hayes, S. D., Harper, J. W., & Howley, P. M. (2012) · Journal of Virology

Cervical Cancer and HPV ResearchCancer-related Molecular Pathways

Cited by 198

Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses

White, E. A., Sowa, M. E., Tan, M. J. A., Jeudy, S., Hayes, S. D., Santha, S., Münger, K., Harper, J. W., & Howley, P. M. (2012) · Proceedings of the National Academy of Sciences

Cervical Cancer and HPV ResearchUbiquitin and proteasome pathways

Cited by 198

Harnessing the Ubiquitination Machinery to Target the Degradation of Specific Cellular Proteins

Zhou, P., Bogacki, R., McReynolds, L., & Howley, P. M. (2000) · Molecular Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 164

Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling

Tan, M. J. A., White, E. A., Sowa, M. E., Harper, J. W., Aster, J. C., & Howley, P. M. (2012) · Proceedings of the National Academy of Sciences

Cervical Cancer and HPV ResearchDevelopmental Biology and Gene Regulation

Cited by 132