Rorsman, Patrik

A pancreatic islet-specific microRNA regulates insulin secretion

Poy, M. N., Eliasson, L., Krutzfeldt, J., Kuwajima, S., Ma, X., MacDonald, P. E., Pfeffer, S., Tuschl, T., Rajewsky, N., Rorsman, P., et al. (2004) · Nature

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 2,102

Diabetes Mellitus and the β Cell: The Last Ten Years

Ashcroft, F. M., & Rorsman, P. (2012) · Cell

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 902

Insulin granule dynamics in pancreatic beta cells

Rorsman, P., & Renstr�m, E. (2003) · Diabetologia

Pancreatic function and diabetesCellular transport and secretion

Cited by 844

Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men

Rorsman, P., & Ashcroft, F. M. (2018) · Physiological Reviews

Pancreatic function and diabetesIon channel regulation and function

Cited by 793

miR-375 maintains normal pancreatic α- and β-cell mass

Poy, M. N., Hausser, J., Trajkovski, M., Braun, M., Collins, S., Rorsman, P., Zavolan, M., & Stoffel, M. (2009) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 740

Regulation of Insulin Secretion in Human Pancreatic Islets

Rorsman, P., & Braun, M. (2013) · Annual Review of Physiology

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 599

Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion

Braun, M., Ramracheya, R., Bengtsson, M., Zhang, Q., Karanauskaite, J., Partridge, C., Johnson, P. R., & Rorsman, P. (2008) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 417

Glucose dependent K+-channels in pancreatic?-cells are regulated by intracellular ATP

Rorsman, P., & Trube, G. (1985) · Pfl�gers Archiv European Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 387

Calcium and delayed potassium currents in mouse pancreatic beta‐cells under voltage‐clamp conditions.

Rorsman, P., & Trube, G. (1986) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 362

Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes.

Fuhlendorff, J., Rorsman, P., Kofod, H., Brand, C. L., Rolin, B., MacKay, P., Shymko, R., & Carr, R. D. (1998) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 310

Protein kinase A‐dependent and ‐independent stimulation of exocytosis by cAMP in mouse pancreatic B‐cells

Renström, E., Eliasson, L., & Rorsman, P. (1997) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 299

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

Olofsson, C. S., Göpel, S. O., Barg, S., Galvanovskis, J., Ma, X., Salehi, A., Rorsman, P., & Eliasson, L. (2002) · Pflügers Archiv

Pancreatic function and diabetesCellular transport and secretion

Cited by 290

The voltage sensitive Lc-type Ca 2+ channel is functionally coupled to the exocytotic machinery

Wiser, O., Trus, M., Hernández, A., Renström, E., Barg, S., Rorsman, P., & Atlas, D. (1999) · Proceedings of the National Academy of Sciences

Cellular transport and secretionIon channel regulation and function

Cited by 284

MicroRNA-7a regulates pancreatic β cell function

Latreille, M., Hausser, J., Stützer, I., Zhang, Q., Hastoy, B., Gargani, S., Kerr-Conte, J., Pattou, F., Zavolan, M., Esguerra, J. L. S., et al. (2014) · Journal of Clinical Investigation

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 281

KATP channels and islet hormone secretion: new insights and controversies

Ashcroft, F. M., & Rorsman, P. (2013) · Nature Reviews Endocrinology

Pancreatic function and diabetesIon channel regulation and function

Cited by 272

Exocytosis elicited by action potentials and voltage‐clamp calcium currents in individual mouse pancreatic B‐cells.

Ammälä, C., Eliasson, L., Bokvist, K., Larsson, O., Ashcroft, F. M., & Rorsman, P. (1993) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 270

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

Brereton, M. F., Iberl, M., Shimomura, K., Zhang, Q., Adriaenssens, A. E., Proks, P., Spiliotis, I. I., Dace, W., Mattis, K. K., Ramracheya, R., et al. (2014) · Nature Communications

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 259

The somatostatin-secreting pancreatic δ-cell in health and disease

Rorsman, P., & Huising, M. O. (2018) · Nature Reviews Endocrinology

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 259

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

De Marinis, Y. Z., Salehi, A., Ward, C. E., Zhang, Q., Abdulkader, F., Bengtsson, M., Braha, O., Braun, M., Ramracheya, R., Amisten, S., et al. (2010) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 257

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells

Eliasson, L., Ma, X., Renström, E., Barg, S., Berggren, P.-O., Galvanovskis, J., Gromada, J., Jing, X., Lundquist, I., Salehi, A., et al. (2003) · The Journal of General Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 257

Stimulus-secretion coupling in pancreatic β cells

Ashcroft, F. M., Proks, P., Smith, P. A., Ämmälä, C., Bokvist, K., & Rorsman, P. (1994) · Journal of Cellular Biochemistry

Pancreatic function and diabetesIon channel regulation and function

Cited by 255

Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells

Barg, S., Ma, X., Eliasson, L., Galvanovskis, J., Göpel, S. O., Obermüller, S., Platzer, J., Renström, E., Trus, M., Atlas, D., et al. (2001) · Biophysical Journal

Pancreatic function and diabetesCellular transport and secretion

Cited by 255

γ-Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic β-Cells

Braun, M., Ramracheya, R., Bengtsson, M., Clark, A., Walker, J. N., Johnson, P. R., & Rorsman, P. (2010) · Diabetes

Pancreatic function and diabetesNeuroscience and Neuropharmacology Research

Cited by 239

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

Rosengren, A. H., Braun, M., Mahdi, T., Andersson, S. A., Travers, M. E., Shigeto, M., Zhang, E., Almgren, P., Ladenvall, C., Axelsson, A. S., et al. (2012) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 237