Rorsman, Patrik

Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells.

Smith, P. A., Bokvist, K., Arkhammar, P., Berggren, P. O., & Rorsman, P. (1990) · The Journal of general physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 86

The Effects of TAK-875, a Selective G Protein-Coupled Receptor 40/Free Fatty Acid 1 Agonist, on Insulin and Glucagon Secretion in Isolated Rat and Human Islets

Yashiro, H., Tsujihata, Y., Takeuchi, K., Hazama, M., Johnson, P. R. V., & Rorsman, P. (2012) · The Journal of Pharmacology and Experimental Therapeutics

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 84

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta‐cells.

Larsson, O., Ammälä, C., Bokvist, K., Fredholm, B., & Rorsman, P. (1993) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 84

Cell coupling in mouse pancreatic β-cells measured in intact islets of Langerhans

Zhang, Q., Galvanovskis, J., Abdulkader, F., Partridge, C. J., Göpel, S. O., Eliasson, L., & Rorsman, P. (2008) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences

Pancreatic function and diabetesConnexins and lens biology

Cited by 80

GABA B receptor activation inhibits exocytosis in rat pancreatic β‐cells by G‐protein‐dependent activation of calcineurin

Braun, M., Wendt, A., Buschard, K., Salehi, A., Sewing, S., Gromada, J., & Rorsman, P. (2004) · The Journal of Physiology

Pancreatic function and diabetesReceptor Mechanisms and Signaling

Cited by 80

Synaptotagmin-7 phosphorylation mediates GLP-1–dependent potentiation of insulin secretion from β-cells

Wu, B., Wei, S., Petersen, N., Ali, Y., Wang, X., Bacaj, T., Rorsman, P., Hong, W., Südhof, T. C., & Han, W. (2015) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesCellular transport and secretion

Cited by 76

CAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic β Cells

Speidel, D., Salehi, A., Obermueller, S., Lundquist, I., Brose, N., Renström, E., & Rorsman, P. (2008) · Cell Metabolism

Pancreatic function and diabetesCellular transport and secretion

Cited by 75

Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca2+ Channels From Secretory Vesicles

Collins, S. C., Hoppa, M. B., Walker, J. N., Amisten, S., Abdulkader, F., Bengtsson, M., Fearnside, J., Ramracheya, R., Toye, A. A., Zhang, Q., et al. (2010) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 73

Calcium increases endocytotic vesicle size and accelerates membrane fission in insulin-secreting INS-1 cells

MacDonald, P. E., Eliasson, L., & Rorsman, P. (2005) · Journal of Cell Science

Cellular transport and secretionPancreatic function and diabetes

Cited by 72

Effects of external tetraethylammonium ions and quinine on delayed rectifying K+ channels in mouse pancreatic beta‐cells.

Bokvist, K., Rorsman, P., & Smith, P. A. (1990) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 69

Exocytotic Properties of Human Pancreatic β‐cells

Braun, M., Ramracheya, R., Johnson, P. R., & Rorsman, P. (2009) · Annals of the New York Academy of Sciences

Pancreatic function and diabetesCellular transport and secretion

Cited by 60

Functional identification of islet cell types by electrophysiological fingerprinting

Briant, L. J. B., Zhang, Q., Vergari, E., Kellard, J. A., Rodriguez, B., Ashcroft, F. M., & Rorsman, P. (2017) · Journal of The Royal Society Interface

Pancreatic function and diabetesNeural dynamics and brain function

Cited by 59

Kiss-and-run exocytosis and fusion pores of secretory vesicles in human β-cells

Hanna, S. T., Pigeau, G. M., Galvanovskis, J., Clark, A., Rorsman, P., & MacDonald, P. E. (2009) · Pflügers Archiv - European Journal of Physiology

Cellular transport and secretionPancreatic function and diabetes

Cited by 57

Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K + -channels in mouse pancreatic β-cells

Bokvist, K. B., Ämmälä, C., Ashcroft, F. M., Berggren, P., Larsson, O., & Rorsman, P. (1991) · Proceedings of the Royal Society of London. Series B: Biological Sciences

Ion channel regulation and functionPancreatic function and diabetes

Cited by 54

Suppression of Sulfonylurea- and Glucose-Induced Insulin Secretion In Vitro and In Vivo in Mice Lacking the Chloride Transport Protein ClC-3

Li, D.-Q., Jing, X., Salehi, A., Collins, S. C., Hoppa, M. B., Rosengren, A. H., Zhang, E., Lundquist, I., Olofsson, C. S., Mörgelin, M., et al. (2009) · Cell Metabolism

Pancreatic function and diabetesCellular transport and secretion

Cited by 50

Compound exocytosis in voltage-clamped mouse pancreatic β-cells revealed by carbon fibre amperometry

Bokvist, K., Holmqvist, M., Gromada, J., & Rorsman, P. (2000) · Pfl�gers Archiv European Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 48

G protein‐dependent inhibition of L‐type Ca2+ currents by acetylcholine in mouse pancreatic B‐cells.

Gilon, P., Yakel, J., Gromada, J., Zhu, Y., Henquin, J. C., & Rorsman, P. (1997) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 47

Large dense-core vesicle exocytosis in pancreatic β-cells monitored by capacitance measurements

Kanno, T., Ma, X., Barg, S., Eliasson, L., Galvanovskis, J., Göpel, S., Larsson, M., Renström, E., & Rorsman, P. (2004) · Methods

Pancreatic function and diabetesCellular transport and secretion

Cited by 44

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta cells

Vergari, E., Denwood, G., Salehi, A., Zhang, Q., Adam, J., Alrifaiy, A., Wernstedt Asterholm, I., Benrick, A., Chibalina, M. V., Eliasson, L., et al. (2020) · Nature Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 43

β Cell Dysfunction in Type 2 Diabetes: Drained of Energy?

Knudsen, J. G., & Rorsman, P. (2019) · Cell Metabolism

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 42

Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes

Hill, T. G., Gao, R., Benrick, A., Kothegala, L., Rorsman, N., Santos, C., Acreman, S., Briant, L. J., Dou, H., Gandasi, N. R., et al. (2024) · Nature Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 37

Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial‐like ATP‐sensitive K+ (KATP) conductance in rat pancreatic A‐cells

Høy, M., Olsen, H. L., Bokvist, K., Buschard, K., Barg, S., Rorsman, P., & Gromada, J. (2000) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 32

GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion

Gandasi, N. R., Gao, R., Kothegala, L., Pearce, A., Santos, C., Acreman, S., Basco, D., Benrick, A., Chibalina, M. V., Clark, A., et al. (2024) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 31

Alpha2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic β-cells

Bokvist, K., Ämmälä, C., Berggren, P.-O., Rorsman, P., & Wåhlander, K. (1991) · Bioscience Reports

Pancreatic function and diabetesIon channel regulation and function

Cited by 25