Rorsman, Patrik

Impaired insulin secretion and glucose tolerance in β cell‐selective CaV1.2 Ca2+ channel null mice

Schulla, V., Renström, E., Feil, R., Feil, S., Franklin, I., Gjinovci, A., Jing, X., Laux, D., Lundquist, I., Magnuson, M. A., et al. (2003) · The EMBO Journal

Pancreatic function and diabetesIon channel regulation and function

Cited by 234

Regulation of glucagon release in mouse α‐cells by KATP channels and inactivation of TTX‐sensitive Na+ channels

Göpel, S. O., Kanno, T., Barg, S., Weng, X. ‐., Gromada, J., & Rorsman, P. (2000) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 229

A Subset of 50 Secretory Granules in Close Contact With l-Type Ca2+ Channels Accounts for First-Phase Insulin Secretion in Mouse β-Cells

Barg, S., Eliasson, L., Renström, E., & Rorsman, P. (2002) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 227

Voltage‐gated and resting membrane currents recorded from B‐cells in intact mouse pancreatic islets

Göpel, S., Kanno, T., Barg, S., Galvanovskis, J., & Rorsman, P. (1999) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 226

Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

Zhang, Q., Ramracheya, R., Lahmann, C., Tarasov, A., Bengtsson, M., Braha, O., Braun, M., Brereton, M., Collins, S., Galvanovskis, J., et al. (2013) · Cell Metabolism

Pancreatic function and diabetesIon channel regulation and function

Cited by 225

Rapid ATP‐Dependent Priming of Secretory Granules Precedes Ca 2+ ‐Induced Exocytosis in Mouse Pancreatic B‐Cells

Eliasson, L., Renström, E., Ding, W., Proks, P., & Rorsman, P. (1997) · The Journal of Physiology

Cellular transport and secretionPancreatic function and diabetes

Cited by 223

Regulation of calcium in pancreatic α- and β-cells in health and disease

Rorsman, P., Braun, M., & Zhang, Q. (2012) · Cell Calcium

Pancreatic function and diabetesIon channel regulation and function

Cited by 220

Delay between Fusion Pore Opening and Peptide Release from Large Dense-Core Vesicles in Neuroendocrine Cells

Barg, S., Olofsson, C. S., Schriever-Abeln, J., Wendt, A., Gebre-Medhin, S., Renström, E., & Rorsman, P. (2002) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 210

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

Barg, S., Galvanovskis, J., Göpel, S. O., Rorsman, P., & Eliasson, L. (2000) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 209

Novel aspects of the molecular mechanisms controlling insulin secretion

Eliasson, L., Abdulkader, F., Braun, M., Galvanovskis, J., Hoppa, M. B., & Rorsman, P. (2008) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 198

Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

Barg, S., Huang, P., Eliasson, L., Nelson, D. J., Obermüller, S., Rorsman, P., Thévenod, F., & Renström, E. (2001) · Journal of Cell Science

Pancreatic function and diabetesCellular transport and secretion

Cited by 194

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

Shigeto, M., Ramracheya, R., Tarasov, A. I., Cha, C. Y., Chibalina, M. V., Hastoy, B., Philippaert, K., Reinbothe, T., Rorsman, N., Salehi, A., et al. (2015) · Journal of Clinical Investigation

Pancreatic function and diabetesIon Channels and Receptors

Cited by 189

Neurotransmitter-Induced Inhibition of Exocytosis in Insulin-Secreting β Cells by Activation of Calcineurin

Renström, E., Ding, W.-G., Bokvist, K., & Rorsman, P. (1996) · Neuron

Pancreatic function and diabetesCellular transport and secretion

Cited by 186

Simultaneous recordings of glucose dependent electrical activity and ATP‐regulated K+‐currents in isolated mouse pancreatic β‐cells

Smith, P. A., Ashcroft, F. M., & Rorsman, P. (1990) · FEBS Letters

Pancreatic function and diabetesIon channel regulation and function

Cited by 169

A TP-Sensitive K+ Channel–Dependent Regulation of Glucagon Release and Electrical Activity by Glucose in Wild-Type and SUR1−/− Mouse α-Cells

Gromada, J., Ma, X., Høy, M., Bokvist, K., Salehi, A., Berggren, P.-O., & Rorsman, P. (2004) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 164

SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells

Kailey, B., van de Bunt, M., Cheley, S., Johnson, P. R., MacDonald, P. E., Gloyn, A. L., Rorsman, P., & Braun, M. (2012) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesReceptor Mechanisms and Signaling

Cited by 164

Capacitance measurements of exocytosis in mouse pancreatic α‐, β‐ and δ‐cells within intact islets of Langerhans

Göpel, S., Zhang, Q., Eliasson, L., Ma, X., Galvanovskis, J., Kanno, T., Salehi, A., & Rorsman, P. (2004) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 160

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

Gheni, G., Ogura, M., Iwasaki, M., Yokoi, N., Minami, K., Nakayama, Y., Harada, K., Hastoy, B., Wu, X., Takahashi, H., et al. (2014) · Cell Reports

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 156

δ‐cells and β‐cells are electrically coupled and regulate α‐cell activity via somatostatin

Briant, L. J. B., Reinbothe, T. M., Spiliotis, I., Miranda, C., Rodriguez, B., & Rorsman, P. (2018) · The Journal of Physiology

Pancreatic function and diabetesConnexins and lens biology

Cited by 155

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Vergari, E., Knudsen, J. G., Ramracheya, R., Salehi, A., Zhang, Q., Adam, J., Asterholm, I. W., Benrick, A., Briant, L. J. B., Chibalina, M. V., et al. (2019) · Nature Communications

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 152

Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory Granules

Hoppa, M. B., Collins, S., Ramracheya, R., Hodson, L., Amisten, S., Zhang, Q., Johnson, P., Ashcroft, F. M., & Rorsman, P. (2009) · Cell Metabolism

Pancreatic function and diabetesCellular transport and secretion

Cited by 152

ATP-sensitive K+ channels: a link between B-cell metabolism and insulin secretion

ASHCROFT, F. M., & RORSMAN, P. (1990) · Biochemical Society Transactions

Pancreatic function and diabetesIon channel regulation and function

Cited by 145

Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic β -cells

Smith, P. A., Rorsman, P., & Ashcroft, F. M. (1989) · Nature

Pancreatic function and diabetesIon channel regulation and function

Cited by 143

Selective nucleotide-release from dense-core granules in insulin-secreting cells

Obermüller, S., Lindqvist, A., Karanauskaite, J., Galvanovskis, J., Rorsman, P., & Barg, S. (2005) · Journal of Cell Science

Cellular transport and secretionPancreatic function and diabetes

Cited by 138