Trompet, Stella

Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis

Reith, C., Preiss, D., Blackwell, L., Emberson, J., Spata, E., Davies, K., Halls, H., Harper, C., Holland, L., Wilson, K., et al. (2024) · The Lancet Diabetes & Endocrinology

Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 161

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 161

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

Lubitz, S. A., Lunetta, K. L., Lin, H., Arking, D. E., Trompet, S., Li, G., Krijthe, B. P., Chasman, D. I., Barnard, J., Kleber, M. E., et al. (2014) · Journal of the American College of Cardiology

Atrial Fibrillation Management and OutcomesGenetic Associations and Epidemiology

Cited by 148

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., et al. (2016) · Molecular Psychiatry

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 147

Sex differences in dementia risk and risk factors: individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium

Gong, J., Harris, K., Lipnicki, D. M., Castro‐Costa, E., Lima‐Costa, M. F., Diniz, B. S., Xiao, S., Lipton, R. B., Katz, M. J., Wang, C., et al. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchMenopause: Health Impacts and Treatments

Cited by 141

Metabolic Age Based on the BBMRI-NL 1 H-NMR Metabolomics Repository as Biomarker of Age-related Disease

van den Akker, E. B., Trompet, S., Barkey Wolf, J. J. H., Beekman, M., Suchiman, H. E. D., Deelen, J., Asselbergs, F. W., Boersma, E., Cats, D., Elders, P. M., et al. (2020) · Circulation: Genomic and Precision Medicine

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 109

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

Sliz, E., Kettunen, J., Holmes, M. V., Williams, C. O., Boachie, C., Wang, Q., Männikkö, M., Sebert, S., Walters, R., Lin, K., et al. (2018) · Circulation

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 109

Association of common genetic variants with brain microbleeds: a genome-wide association study

Knol, M. J., Lu, D., Traylor, M., Adams, H. H. H., Romero, J. R. J., Smith, A. V., Fornage, M., Hofer, E., Liu, J., Hostettler, I. C., et al. (2020) · Neurology

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 94

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites

Kent, S. T., Rosenson, R. S., Avery, C. L., Chen, Y.-D. I., Correa, A., Cummings, S. R., Cupples, L. A., Cushman, M., Evans, D. S., Gudnason, V., et al. (2017) · Circulation: Cardiovascular Genetics

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 86

Survival Bias in Mendelian Randomization Studies: A Threat to Causal Inference

Smit, R. A. J., Trompet, S., Dekkers, O. M., Jukema, J. W., & le Cessie, S. (2019) · Epidemiology

Advanced Causal Inference TechniquesGenetic Associations and Epidemiology

Cited by 83

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

The QT Interval International GWAS Consortium (QT-IGC), Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S.-P., Brunak, S., et al. (2014) · Nature Methods

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 71

Subclinical Thyroid Dysfunction and Cognitive Decline in Old Age

Wijsman, L. W., de Craen, A. J. M., Trompet, S., Gussekloo, J., Stott, D. J., Rodondi, N., Welsh, P., Jukema, J. W., Westendorp, R. G. J., & Mooijaart, S. P. (2013) · PLoS ONE

Thyroid Disorders and TreatmentsDementia and Cognitive Impairment Research

Cited by 68

PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population

Postmus, I., Trompet, S., de Craen, A. J. M., Buckley, B. M., Ford, I., Stott, D. J., Sattar, N., Slagboom, P. E., Westendorp, R. G. J., & Jukema, J. W. (2013) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 67

Type 2 diabetes partitioned polygenic scores associate with disease outcomes in 454,193 individuals across 13 cohorts

DiCorpo, D., LeClair, J., Cole, J. B., Sarnowski, C., Ahmadizar, F., Bielak, L. F., Blokstra, A., Bottinger, E. P., Chaker, L., Chen, Y.-D. I., et al. (2022) · Diabetes Care

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 66

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S.-J., Isaacs, A., et al. (2016) · Circulation: Cardiovascular Genetics

Genetic Associations and EpidemiologyAtherosclerosis and Cardiovascular Diseases

Cited by 66

The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis

Xu, Y., Derakhshan, A., Hysaj, O., Wildisen, L., Ittermann, T., Pingitore, A., Abolhassani, N., Medici, M., Kiemeney, L. A. L. M., Riksen, N. P., et al. (2023) · The Lancet Diabetes & Endocrinology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 61

Does Low to Moderate Alcohol Intake Protect Against Cognitive Decline in Older People?

Stott, D. J., Falconer, A., Kerr, G. D., Murray, H. M., Trompet, S., Westendorp, R. G. J., Buckley, B., De Craen, A. J. M., Sattar, N., & Ford, I. (2008) · Journal of the American Geriatrics Society

Dementia and Cognitive Impairment ResearchAlcohol Consumption and Health Effects

Cited by 55

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., et al. (2018) · Nature Communications

Genetic Associations and EpidemiologyCerebrospinal fluid and hydrocephalus

Cited by 52

Evaluation of high cholesterol and risk of dementia and cognitive decline in older adults using individual patient meta-analysis

Peters, R., Xu, Y., Antikainen, R., Beckett, N., Gussekloo, J., Jagger, C., Jukema, J. W., Keinanen-Kiukaanniemi, S., Rydén, L., Skoog, I., et al. (2021) · Dementia and Geriatric Cognitive Disorders

Dementia and Cognitive Impairment ResearchLipoproteins and Cardiovascular Health

Cited by 51

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J.-W., et al. (2022) · Nature Communications

Cardiac electrophysiology and arrhythmiasGenetic Associations and Epidemiology

Cited by 49