Dick, John E.

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Lapidot, T., Sirard, C., Vormoor, J., Murdoch, B., Hoang, T., Caceres-Cortes, J., Minden, M., Paterson, B., Caligiuri, M. A., & Dick, J. E. (1994) · Nature

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 4,783

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Zhang, J., Ding, L., Holmfeldt, L., Wu, G., Heatley, S. L., Payne-Turner, D., Easton, J., Chen, X., Wang, J., Rusch, M., et al. (2012) · Nature

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 1,596

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

Shlush, L. I., Zandi, S., Mitchell, A., Chen, W. C., Brandwein, J. M., Gupta, V., Kennedy, J. A., Schimmer, A. D., Schuh, A. C., Yee, K. W., et al. (2014) · Nature

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 1,443

Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry

Bandura, D. R., Baranov, V. I., Ornatsky, O. I., Antonov, A., Kinach, R., Lou, X., Pavlov, S., Vorobiev, S., Dick, J. E., & Tanner, S. D. (2009) · Analytical Chemistry

Mass Spectrometry Techniques and ApplicationsAnalytical chemistry methods development

Cited by 1,295

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

Notta, F., Doulatov, S., Laurenti, E., Poeppl, A., Jurisica, I., & Dick, J. E. (2011) · Science

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 919

A 17-gene stemness score for rapid determination of risk in acute leukaemia

Ng, S. W. K., Mitchell, A., Kennedy, J. A., Chen, W. C., McLeod, J., Ibrahimova, N., Arruda, A., Popescu, A., Gupta, V., Schimmer, A. D., et al. (2016) · Nature

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 912

Hematopoiesis: a human perspective

Doulatov, S., Notta, F., Laurenti, E., & Dick, J. E. (2012) · Cell stem cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 895

Prediction of acute myeloid leukaemia risk in healthy individuals

Abelson, S., Collord, G., Ng, S. W. K., Weissbrod, O., Mendelson Cohen, N., Niemeyer, E., Barda, N., Zuzarte, P. C., Heisler, L., Sundaravadanam, Y., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 850

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

Notta, F., Zandi, S., Takayama, N., Dobson, S., Gan, O. I., Wilson, G., Kaufmann, K. B., McLeod, J., Laurenti, E., Dunant, C. F., et al. (2016) · Science

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 780

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Schenk, T., Chen, W. C., Göllner, S., Howell, L., Jin, L., Hebestreit, K., Klein, H.-U., Popescu, A. C., Burnett, A., Mills, K., et al. (2012) · Nature Medicine

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 672

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

Notta, F., Chan-Seng-Yue, M., Lemire, M., Li, Y., Wilson, G. W., Connor, A. A., Denroche, R. E., Liang, S.-B., Brown, A. M. K., Kim, J. C., et al. (2016) · Nature

Cancer Genomics and DiagnosticsPancreatic and Hepatic Oncology Research

Cited by 528

Self-renewal as a therapeutic target in human colorectal cancer

Kreso, A., van Galen, P., Pedley, N. M., Lima-Fernandes, E., Frelin, C., Davis, T., Cao, L., Baiazitov, R., Du, W., Sydorenko, N., et al. (2014) · Nature Medicine

Cancer Cells and MetastasisEpigenetics and DNA Methylation

Cited by 500

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

van Galen, P., Kreso, A., Mbong, N., Kent, D. G., Fitzmaurice, T., Chambers, J. E., Xie, S., Laurenti, E., Hermans, K., Eppert, K., et al. (2014) · Nature

Hematopoietic Stem Cell TransplantationEndoplasmic Reticulum Stress and Disease

Cited by 363

A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

Bahr, C., von Paleske, L., Uslu, V. V., Remeseiro, S., Takayama, N., Ng, S. W., Murison, A., Langenfeld, K., Petretich, M., Scognamiglio, R., et al. (2018) · Nature

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 328

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells

Surka, C., Jin, L., Mbong, N., Lu, C.-C., Jang, I. S., Rychak, E., Mendy, D., Clayton, T., Tindall, E., Hsu, C., et al. (2021) · Blood

Protein Degradation and InhibitorsAcute Myeloid Leukemia Research

Cited by 229

Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion

Lechman, E. R., Gentner, B., van Galen, P., Giustacchini, A., Saini, M., Boccalatte, F. E., Hiramatsu, H., Restuccia, U., Bachi, A., Voisin, V., et al. (2012) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMicroRNA in disease regulation

Cited by 208

Integrated stress response activity marks stem cells in normal hematopoiesis and leukemia

van Galen, P., Mbong, N., Kreso, A., Schoof, E. M., Wagenblast, E., Ng, S. W. K., Krivdova, G., Jin, L., Nakauchi, H., & Dick, J. E. (2018) · Cell Reports

Hematopoietic Stem Cell TransplantationEndoplasmic Reticulum Stress and Disease

Cited by 131

Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging

Jakobsen, N. A., Turkalj, S., Zeng, A. G. X., Stoilova, B., Metzner, M., Rahmig, S., Nagree, M. S., Shah, S., Moore, R., Usukhbayar, B., et al. (2024) · Cell Stem Cell

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

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Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs

Dobson, S. M., García-Prat, L., Vanner, R. J., Wintersinger, J., Waanders, E., Gu, Z., McLeod, J., Gan, O. I., Grandal, I., Payne-Turner, D., et al. (2020) · Cancer Discovery

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

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A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness

Kaufmann, K. B., Zeng, A. G. X., Coyaud, E., Garcia-Prat, L., Papalexi, E., Murison, A., Laurent, E. M. N., Chan-Seng-Yue, M., Gan, O. I., Pan, K., et al. (2021) · Nature Immunology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

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Ectopic miR-125a expression induces long-term repopulating stem cell capacity in mouse and human hematopoietic progenitors

Wojtowicz, E. E., Lechman, E. R., Hermans, K. G., Schoof, E. M., Wienholds, E., Isserlin, R., van Veelen, P. A., Broekhuis, M. J. C., Janssen, G. M. C., Trotman-Grant, A., et al. (2016) · Cell stem cell

Hematopoietic Stem Cell TransplantationMicroRNA in disease regulation

Cited by 60

Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

Bahr, C., von Paleske, L., Uslu, V. V., Remeseiro, S., Takayama, N., Ng, S. W., Murison, A., Langenfeld, K., Petretich, M., Scognamiglio, R., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 11

Human haematopoietic stem cells remember inflammatory stress

Zeng, A. G. X., Nagree, M. S., Jakobsen, N. A., Shah, S., Varesi, A., Kang, J. R. W., Murison, A., Cheong, J.-G., Turkalj, S., Zhang, X., et al. (2026) · Nature

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 10