Randolph, Gwendalyn J.

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

the Immunological Genome Consortium, Gautier, E. L., Shay, T., Miller, J., Greter, M., Jakubzick, C., Ivanov, S., Helft, J., Chow, A., Elpek, K. G., et al. (2012) · Nature Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,972

Origin and functions of tissue macrophages

Epelman, S., Lavine, K. J., & Randolph, G. J. (2014) · Immunity

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,585

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

Epelman, S., Lavine, K. J., Beaudin, A. E., Sojka, D. K., Carrero, J. A., Calderon, B., Brija, T., Gautier, E. L., Ivanov, S., Satpathy, A. T., et al. (2014) · Immunity

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

Cited by 1,494

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

Tacke, F., Alvarez, D., Kaplan, T. J., Jakubzick, C., Spanbroek, R., Llodra, J., Garin, A., Liu, J., Mack, M., van Rooijen, N., et al. (2007) · Journal of Clinical Investigation

Atherosclerosis and Cardiovascular DiseasesChemokine receptors and signaling

Cited by 1,323

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

Shankman, L. S., Gomez, D., Cherepanova, O. A., Salmon, M., Alencar, G. F., Haskins, R. M., Swiatlowska, P., Newman, A. A. C., Greene, E. S., Straub, A. C., et al. (2015) · Nature Medicine

Atherosclerosis and Cardiovascular DiseasesKruppel-like factors research

Cited by 1,218

Dendritic-cell trafficking to lymph nodes through lymphatic vessels

Randolph, G. J., Angeli, V., & Swartz, M. A. (2005) · Nature Reviews Immunology

Lymphatic System and DiseasesImmunotherapy and Immune Responses

Cited by 1,111

Monocyte differentiation and antigen-presenting functions

Jakubzick, C. V., Randolph, G. J., & Henson, P. M. (2017) · Nature Reviews Immunology

Immune cells in cancerImmunotherapy and Immune Responses

Cited by 910

Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart

Lavine, K. J., Epelman, S., Uchida, K., Weber, K. J., Nichols, C. G., Schilling, J. D., Ornitz, D. M., Randolph, G. J., & Mann, D. L. (2014) · Proceedings of the National Academy of Sciences

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 818

Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis

Bambouskova, M., Gorvel, L., Lampropoulou, V., Sergushichev, A., Loginicheva, E., Johnson, K., Korenfeld, D., Mathyer, M. E., Kim, H., Huang, L.-H., et al. (2018) · Nature

NF-κB Signaling PathwaysGenomics, phytochemicals, and oxidative stress

Cited by 713

Migratory fate and differentiation of blood monocyte subsets

Tacke, F., & Randolph, G. J. (2006) · Immunobiology

Immune cells in cancerImmunotherapy and Immune Responses

Cited by 528

Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models

Kim, K., Shim, D., Lee, J. S., Zaitsev, K., Williams, J. W., Kim, K.-W., Jang, M.-Y., Seok Jang, H., Yun, T. J., Lee, S. H., et al. (2018) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 434

GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

Greter, M., Helft, J., Chow, A., Hashimoto, D., Mortha, A., Agudo-Cantero, J., Bogunovic, M., Gautier, E. L., Miller, J., Leboeuf, M., et al. (2012) · Immunity

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 433

Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth

Ensan, S., Li, A., Besla, R., Degousee, N., Cosme, J., Roufaiel, M., Shikatani, E. A., El-Maklizi, M., Williams, J. W., Robins, L., et al. (2016) · Nature Immunology

Atherosclerosis and Cardiovascular DiseasesImmune cells in cancer

Cited by 372

The lymphatic system: integral roles in immunity

Randolph, G. J., Ivanov, S., Zinselmeyer, B. H., & Scallan, J. P. (2017) · Annual Review of Immunology

Lymphatic System and DiseasesLymphatic Disorders and Treatments

Cited by 338

Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid

Drieu, A., Du, S., Storck, S. E., Rustenhoven, J., Papadopoulos, Z., Dykstra, T., Zhong, F., Kim, K., Blackburn, S., Mamuladze, T., et al. (2022) · Nature

Cerebrospinal fluid and hydrocephalusNeuroinflammation and Neurodegeneration Mechanisms

Cited by 325

The pancreas anatomy conditions the origin and properties of resident macrophages

Calderon, B., Carrero, J. A., Ferris, S. T., Sojka, D. K., Moore, L., Epelman, S., Murphy, K. M., Yokoyama, W. M., Randolph, G. J., & Unanue, E. R. (2015) · Journal of Experimental Medicine

Immune cells in cancerPancreatic function and diabetes

Cited by 321

Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity

Fonseca, D. M. D., Hand, T. W., Han, S.-J., Gerner, M. Y., Zaretsky, A. G., Byrd, A. L., Harrison, O. J., Ortiz, A. M., Quinones, M., Trinchieri, G., et al. (2015) · Cell

Gut microbiota and healthImmune Response and Inflammation

Cited by 281

Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity

Westerterp, M., Gautier, E. L., Ganda, A., Molusky, M. M., Wang, W., Fotakis, P., Wang, N., Randolph, G. J., D'Agati, V. D., Yvan-Charvet, L., et al. (2017) · Cell Metabolism

Inflammasome and immune disordersCholesterol and Lipid Metabolism

Cited by 218

Regulation of the Migration and Survival of Monocyte Subsets by Chemokine Receptors and Its Relevance to Atherosclerosis

Gautier, E. L., Jakubzick, C., & Randolph, G. J. (2009) · Arteriosclerosis, Thrombosis, and Vascular Biology

Atherosclerosis and Cardiovascular DiseasesChemokine receptors and signaling

Cited by 216

Tissue-resident macrophages in pancreatic ductal adenocarcinoma originate from embryonic hematopoiesis and promote tumor progression

Zhu, Y., Herndon, J. M., Sojka, D. K., Kim, K.-W., Knolhoff, B. L., Zuo, C., Cullinan, D. R., Luo, J., Bearden, A. R., Lavine, K. J., et al. (2017) · Immunity

Immune cells in cancerPancreatic and Hepatic Oncology Research

Cited by 180

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

Chong, S. Z., Evrard, M., Devi, S., Chen, J., Lim, J. Y., See, P., Zhang, Y., Adrover, J. M., Lee, B., Tan, L., et al. (2016) · Journal of Experimental Medicine

Chemokine receptors and signalingImmune cells in cancer

Cited by 142

Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer’s disease

Yan, P., Kim, K.-W., Xiao, Q., Ma, X., Czerniewski, L. R., Liu, H., Rawnsley, D. R., Yan, Y., Randolph, G. J., Epelman, S., et al. (2022) · Journal of Clinical Investigation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 95

Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor

Czepielewski, R. S., Erlich, E. C., Onufer, E. J., Young, S., Saunders, B. T., Han, Y.-H., Wohltmann, M., Wang, P. L., Kim, K.-W., Kumar, S., et al. (2021) · Immunity

Lymphatic System and DiseasesInflammatory Bowel Disease

Cited by 77

Limited Macrophage Positional Dynamics in Progressing or Regressing Murine Atherosclerotic Plaques—Brief Report

Williams, J. W., Martel, C., Potteaux, S., Esaulova, E., Ingersoll, M. A., Elvington, A., Saunders, B. T., Huang, L.-H., Habenicht, A. J., Zinselmeyer, B. H., et al. (2018) · Arteriosclerosis, Thrombosis, and Vascular Biology

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 53