Tissue-resident macrophages in pancreatic ductal adenocarcinoma originate from embryonic hematopoiesis and promote tumor progression
Open accessIntegrity signals
Registry
Cites
Statistics
Claims the paper makes
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The text we found for this paper looks like another document, so the self-check wasn’t run.
Cites
Still being checked.
Cited by
Sorted by citations
Diversity, Mechanisms, and Significance of Macrophage Plasticity
Locati, M., Curtale, G., & Mantovani, A. (2020) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-012418-012718 · Cited by 2,199 · see citing works
Targeting macrophages: therapeutic approaches in cancer
Cassetta, L., & Pollard, J. W. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2018.169 · Cited by 2,057 · see citing works
Pancreatic cancer: Advances and challenges
Halbrook, C. J., Lyssiotis, C. A., Pasca di Magliano, M., & Maitra, A. (2023) · Cell · doi:10.1016/j.cell.2023.02.014 · Cited by 1,321 · see citing works
Targeting tumor-associated macrophages in cancer
Pathria, P., Louis, T. L., & Varner, J. A. (2019) · Trends in Immunology · doi:10.1016/j.it.2019.02.003 · Cited by 933 · see citing works
Hezaveh, K., Shinde, R. S., Klötgen, A., Halaby, M. J., Lamorte, S., Ciudad, M. T., Quevedo, R., Neufeld, L., Liu, Z. Q., Jin, R., et al. (2022) · Immunity · doi:10.1016/j.immuni.2022.01.006 · Cited by 746 · see citing works
Redefining Tumor-Associated Macrophage Subpopulations and Functions in the Tumor Microenvironment
Wu, K., Lin, K., Li, X., Yuan, X., Xu, P., Ni, P., & Xu, D. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01731 · Cited by 691 · see citing works
Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease
Mulder, K., Patel, A. A., Kong, W. T., Piot, C., Halitzki, E., Dunsmore, G., Khalilnezhad, S., Irac, S. E., Dubuisson, A., Chevrier, M., et al. (2021) · Immunity · doi:10.1016/j.immuni.2021.07.007 · Cited by 678 · see citing works
Macrophages in health and disease
Park, M. D., Silvin, A., Ginhoux, F., & Merad, M. (2022) · Cell · doi:10.1016/j.cell.2022.10.007 · Cited by 644 · see citing works
Metabolism of tissue macrophages in homeostasis and pathology
Wculek, S. K., Dunphy, G., Heras-Murillo, I., Mastrangelo, A., & Sancho, D. (2022) · Cellular & Molecular Immunology · doi:10.1038/s41423-021-00791-9 · Cited by 501 · see citing works
Dai, E., Han, L., Liu, J., Xie, Y., Zeh, H. J., Kang, R., Bai, L., & Tang, D. (2020) · Nature Communications · doi:10.1038/s41467-020-20154-8 · Cited by 428 · see citing works
Plasticity of myeloid-derived suppressor cells in cancer
Tcyganov, E., Mastio, J., Chen, E., & Gabrilovich, D. I. (2018) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.03.009 · Cited by 398 · see citing works
IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer
Caronni, N., Terza, F. L., Vittoria, F. M., Barbiera, G., Mezzanzanica, L., Cuzzola, V., Barresi, S., Pellegatta, M., Canevazzi, P., Dunsmore, G., et al. (2023) · Nature · doi:10.1038/s41586-023-06685-2 · Cited by 407 · see citing works
Diverse Functions of Macrophages in Different Tumor Microenvironments
Yang, M., McKay, D., Pollard, J. W., & Lewis, C. E. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-1367 · Cited by 390 · see citing works
Loeuillard, E. J., Yang, J., Buckarma, E. H., Wang, J., Liu, Y., Conboy, C. B., Pavelko, K. D., Li, Y., O’Brien, D. R., Wang, C., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci137110 · Cited by 370 · see citing works
Hemogenic Endothelial Fate Mapping Reveals Dual Developmental Origin of Mast Cells
Gentek, R., Ghigo, C., Hoeffel, G., Bulle, M. J., Msallam, R., Gautier, G., Launay, P., Chen, J., Ginhoux, F., & Bajénoff, M. (2018) · Immunity · doi:10.1016/j.immuni.2018.04.025 · Cited by 328 · see citing works
Rodríguez, E., Boelaars, K., Brown, K., Li, R. J. E., Kruijssen, L. J. W., Bruijns, S. C. M., van Ee, T., Schetters, S. T. T., Crommentuijn, M. H. W., van der Horst, J. C., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21550-4 · Cited by 319 · see citing works
Hosein, A. N., Huang, H., Wang, Z., Parmar, K., Du, W., Huang, J., Maitra, A., Olson, E., Verma, U., & Brekken, R. A. (2019) · JCI Insight · doi:10.1172/jci.insight.129212 · Cited by 302 · see citing works
Macrophages: The Road Less Traveled, Changing Anticancer Therapy
Guerriero, J. L. (2018) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2018.03.006 · Cited by 293 · see citing works
Macrophages of distinct origins contribute to tumor development in the lung
Loyher, P.-L., Hamon, P., Laviron, M., Meghraoui, A., Gonçalves, E., Deng, Z., Torstensson, S., Bercovici, N., de Chanville, C. B., Combadière, B., et al. (2018) · The Journal of Experimental Medicine · doi:10.1084/jem.20180534 · Cited by 293 · see citing works
Yasuda, T., & Wang, Y. (2024) · Trends in cancer · doi:10.1016/j.trecan.2024.03.008 · Cited by 278 · see citing works
Cassetta, L., & Pollard, J. W. (2020) · Current Biology · doi:10.1016/j.cub.2020.01.031 · Cited by 258 · see citing works
Host tissue determinants of tumour immunity
Salmon, H., Remark, R., Gnjatic, S., & Mérad, M. (2019) · Nature reviews. Cancer · doi:10.1038/s41568-019-0125-9 · Cited by 258 · see citing works
Endometriosis-Associated Macrophages: Origin, Phenotype, and Function
Hogg, C., Horne, A. W., & Greaves, E. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00007 · Cited by 241 · see citing works
Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma
Zhang, T., Ren, Y., Yang, P., Wang, J., & Zhou, H. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05351-1 · Cited by 225 · see citing works
Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer
Falcomatà, C., Bärthel, S., Schneider, G., Rad, R., Schmidt‐Supprian, M., & Saur, D. (2023) · Cancer Discovery · doi:10.1158/2159-8290.cd-22-0876 · Cited by 213 · see citing works
Bulle, A. S., & Lim, K. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00341-1 · Cited by 203 · see citing works
Nixon, B. G., Kuo, F., Ji, L.-L., Liu, M., Capistrano, K. J., Do, M. H., Franklin, R. A., Wu, X.-D., Kansler, E. R., Srivastava, R., et al. (2022) · Immunity · doi:10.1016/j.immuni.2022.10.002 · Cited by 179 · see citing works
Macrophages: shapes and functions
Lendeckel, U., Venz, S., & Wolke, C. (2022) · ChemTexts · doi:10.1007/s40828-022-00163-4 · Cited by 185 · see citing works
Adaptation and memory in immune responses
Natoli, G., & Ostuni, R. (2019) · Nature Immunology · doi:10.1038/s41590-019-0399-9 · Cited by 186 · see citing works
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
Chow, A. T., Schad, S. E., Green, M. D., Hellmann, M. D., Allaj, V., Ceglia, N., Zago, G., Shah, N., Sharma, S. K., Mattar, M. S., et al. (2021) · Cancer Cell · doi:10.1016/j.ccell.2021.05.006 · Cited by 183 · see citing works
Arginase 1 is a key driver of immune suppression in pancreatic cancer
Menjivar, R. E., Nwosu, Z. C., Du, W., Donahue, K. L., Hong, H. S., Espinoza, C. E., Brown, K. L., Velez-Delgado, A., Yan, W., Lima, F., et al. (2023) · eLife · doi:10.7554/elife.80721 · Cited by 180 · see citing works
Re-Education of Macrophages as a Therapeutic Strategy in Cancer
Kowal, J., Kornete, M., & Joyce, J. A. (2019) · Immunotherapy · doi:10.2217/imt-2018-0156 · Cited by 161 · see citing works
Wang, P. L., Yim, A. K., Kim, K.-W., Avey, D. R., Czepielewski, R. S., Colonna, M., Milbrandt, J., Randolph, G. J., & The Immunological Genome Project (2020) · Nature Communications · doi:10.1038/s41467-020-16355-w · Cited by 168 · see citing works
Self-citationMyeloid cell heterogeneity in cancer: not a single cell alike
Kiss, M., Van Gassen, S., Movahedi, K., Saeys, Y., & Laoui, D. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.02.008 · Cited by 159 · see citing works
Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer
Hou, P., Kapoor, A., Zhang, Q., Li, J., Wu, C.-J., Li, J., Lan, Z., Tang, M., Ma, X., Ackroyd, J. J., et al. (2020) · Cancer Discovery · doi:10.1158/2159-8290.cd-19-0597 · Cited by 154 · see citing works
Monocyte Regulation in Homeostasis and Malignancy
Robinson, A., Han, C. Z., Glass, C. K., & Pollard, J. W. (2021) · Trends in Immunology · doi:10.1016/j.it.2020.12.001 · Cited by 155 · see citing works
Redefining macrophage and neutrophil biology in the metastatic cascade
Güç, E., & Pollard, J. W. (2021) · Immunity · doi:10.1016/j.immuni.2021.03.022 · Cited by 140 · see citing works
Tumor-associated macrophages: A promising target for a cancer immunotherapeutic strategy
Zhang, S., Song, X., Yang, L., Ye, L., Zhou, Q., & Yang, W.-B. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105111 · Cited by 135 · see citing works
The biological underpinnings of therapeutic resistance in pancreatic cancerPreprint
Beatty, G. L., Werba, G., Lyssiotis, C. A., & Simeone, D. M. (2021) · Genes & Development · doi:10.1101/gad.348523.121 · Cited by 133 · see citing works
Macrophages inhibit and enhance endometriosis depending on their origin
Hogg, C., Panir, K., Dhami, P., Rosser, M., Mack, M., Soong, D., Pollard, J., Jenkins, S., Horne, A., & Greaves, E. (2021) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2013776118 · Cited by 124 · see citing works
Cellular Senescence and the Immune System in Cancer
Prieto, L. I., & Baker, D. J. (2019) · Gerontology · doi:10.1159/000500683 · Cited by 119 · see citing works
Lau, L., Porciuncula, A., Yu, A., Iwakura, Y., & David, G. (2019) · Molecular and Cellular Biology · doi:10.1128/mcb.00586-18 · Cited by 119 · see citing works
The Generation and Identity of Human Myeloid-Derived Suppressor Cells
Bergenfelz, C., & Leandersson, K. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00109 · Cited by 118 · see citing works
B cell–Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic Cancer
Mirlekar, B., Michaud, D. E., Lee, S. J., Kren, N. P., Harris, C., Greene, K. G., Goldman, E. C., Gupta, G. P., Fields, R. C., Hawkins, W. G., et al. (2020) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-19-0349 · Cited by 118 · see citing works
Self-citationCancer-associated fibroblasts: key determinants of tumor immunity and immunotherapy
Barrett, R., & Puré, E. (2020) · Current Opinion in Immunology · doi:10.1016/j.coi.2020.03.004 · Cited by 117 · see citing works
Epithelial and stromal co-evolution and complicity in pancreatic cancer
Hingorani, S. R. (2023) · Nature Reviews Cancer · doi:10.1038/s41568-022-00530-w · Cited by 108 · see citing works
The emerging roles of macrophages in cancer metastasis and response to chemotherapy
Sanchez, L. R., Borriello, L., Entenberg, D. R., Condeelis, J. S., Oktay, M. H., & Karagiannis, G. S. (2019) · Journal of Leukocyte Biology · doi:10.1002/jlb.mr0218-056rr · Cited by 106 · see citing works
Tumor-Associated Macrophages (TAMs): A Critical Activator In Ovarian Cancer Metastasis
Yin, M., Shen, J., Yu, S., Jing, F., Zhu, X., Zhao, J., Zhai, L., Sadhukhan, A., & Zhou, J. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s216355 · Cited by 107 · see citing works
Training the Fetal Immune System Through Maternal Inflammation—A Layered Hygiene Hypothesis
Apostol, A. C., Jensen, K. D. C., & Beaudin, A. E. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00123 · Cited by 100 · see citing works
Generation, localization and functions of macrophages during the development of testis
Lokka, E., Lintukorpi, L., Cisneros-Montalvo, S., Mäkelä, J.-A., Tyystjärvi, S., Ojasalo, V., Gerke, H., Toppari, J., Rantakari, P., & Salmi, M. (2020) · Nature Communications · doi:10.1038/s41467-020-18206-0 · Cited by 70 · see citing works
Tu, W., Gong, J., Zhou, Z., Tian, D., & Wang, Z. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-04166-w · Cited by 96 · see citing works
Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming
Velez-Delgado, A., Donahue, K. L., Brown, K. L., Du, W., Irizarry-Negron, V., Menjivar, R. E., Lasse Opsahl, E. L., Steele, N. G., The, S., Lazarus, J., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.02.016 · Cited by 91 · see citing works
Novel tumor-associated macrophage populations and subpopulations by single cell RNA sequencing
Wang, J., Zhu, N., Su, L., Gao, Y., & Yang, R. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1264774 · Cited by 91 · see citing works
Mills, B. N., Connolly, K. A., Ye, J., Murphy, J. D., Uccello, T. P., Han, B. J., Zhao, T., Drage, M. G., Murthy, A., Qiu, H., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.08.095 · Cited by 88 · see citing works
Developmental control of macrophage function
Bonnardel, J., & Guilliams, M. (2017) · Current Opinion in Immunology · doi:10.1016/j.coi.2017.12.001 · Cited by 84 · see citing works
Underlying Causes and Therapeutic Targeting of the Inflammatory Tumor Microenvironment
Comen, E. A., Bowman, R. L., & Kleppe, M. (2018) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2018.00056 · Cited by 84 · see citing works
Ahirwar, D. K., Charan, M., Mishra, S., Verma, A. K., Shilo, K., Ramaswamy, B., & Ganju, R. K. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-3909 · Cited by 84 · see citing works
Modeling pancreatic cancer in mice for experimental therapeutics
Mallya, K. B., Gautam, S. K., Aithal, A., Batra, S. K., & Jain, M. (2021) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2021.188554 · Cited by 83 · see citing works
Tumor-associated macrophages: role in tumorigenesis and immunotherapy implications
Zhu, S., Luo, Z., Li, X., Han, X., Shi, S., & Zhang, T. (2020) · Journal of Cancer · doi:10.7150/jca.49692 · Cited by 82 · see citing works
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
Saab, J. J. A., Dzierozynski, L. N., Jonker, P. B., AminiTabrizi, R., Shah, H., Menjivar, R. E., Scott, A. J., Nwosu, Z. C., Zhu, Z., Chen, R. N., et al. (2023) · eLife · doi:10.7554/elife.81289 · Cited by 80 · see citing works
Fetal-derived macrophages dominate in adult mammary glands
Jäppinen, N. T., Félix, I., Lokka, E., Tyystjärvi, S., Pynttäri, A., Lahtela, T., Gerke, H., Elima, K., Rantakari, P., & Salmi, M. (2019) · Nature Communications · doi:10.1038/s41467-018-08065-1 · Cited by 71 · see citing works
Ager, C. R., Boda, A. R., Rajapakshe, K., Lea, S. T., Francesco, M. E. D., Jayaprakash, P., Slay, R., Morrow, B., Prasad, R., Dean, M. A., et al. (2021) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-003246 · Cited by 76 · see citing works
Haubruck, P., Pinto, M. M., Moradi, B., Little, C. B., & Gentek, R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.763702 · Cited by 80 · see citing works
Tumor-associated myeloid cells in cancer immunotherapy
Cheng, X., Wang, H., Wang, Z., Zhu, B., & Long, H. (2023) · Journal of Hematology & Oncology · doi:10.1186/s13045-023-01473-x · Cited by 75 · see citing works
Tissue-resident immune cells: from defining characteristics to roles in diseases
Li, J., Chu, X., Li, C., & He, J. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02050-5 · Cited by 80 · see citing works
Pandey, V., Martinez, A. K. F., Bastea, L. I., Döppler, H. R., Eisenhauer, J., Le, T., Edenfield, B. H., & Störz, P. (2021) · eLife · doi:10.7554/elife.60646 · Cited by 73 · see citing works
Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression
Laplagne, C., Domagala, M., Naour, A. L., Quémerais, C., Hamel, D., Fournié, J., Couderc, B. C., Bousquet, C., Ferrand, A., & Poupot, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20194719 · Cited by 73 · see citing works
Innate immune evasion revealed in a colorectal zebrafish xenograft model
Póvoa, V., de Almeida, C. R., Maia-Gil, M., Sobral, D., Domingues, M., Martínez-López, M. F., Fuzeta, M. D. A., Silva, C., Grosso, A. R., & Fior, R. (2021) · Nature Communications · doi:10.1038/s41467-021-21421-y · Cited by 72 · see citing works
Boelaars, K., Rodríguez, E., Huinen, Z. R., Liu, C., Wang, D., Springer, B. O., Olesek, K., Kruijssen, L. J. W., van Ee, T., Lindijer, D., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-06087-8 · Cited by 72 · see citing works
Cotechini, T., Atallah, A., & Grossman, A. (2021) · Cells · doi:10.3390/cells10040960 · Cited by 69 · see citing works
Macrophages and T cells in metabolic disorder-associated cancers
Taranto, D., Kloosterman, D., & Akkari, L. (2024) · Nature Reviews. Cancer · doi:10.1038/s41568-024-00743-1 · Cited by 67 · see citing works
Stromnes, I. M., Burrack, A. L., Hulbert, A., Bonson, P., Black, C., Brockenbrough, J. S., Raynor, J. F., Spartz, E. J., Pierce, R. H., Greenberg, P. D., et al. (2019) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-18-0448 · Cited by 69 · see citing works
Friend or Foe? Recent Strategies to Target Myeloid Cells in Cancer
Chaib, M., Chauhan, S., & Makowski, L. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00351 · Cited by 62 · see citing works
The unique immune microenvironment of liver metastases: Challenges and opportunities
Ciner, A., Jones, K. I., Muschel, R. J., & Brodt, P. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.06.003 · Cited by 66 · see citing works
mPGES-1 and ALOX5/-15 in tumor-associated macrophages
Weigert, A., Strack, E., Snodgrass, R. G., & Brüne, B. (2018) · Cancer and Metastasis Reviews · doi:10.1007/s10555-018-9731-3 · Cited by 62 · see citing works
Macrophages: Key orchestrators of a tumor microenvironment defined by therapeutic resistance
Long, K. B., Collier, A. I., & Beatty, G. L. (2017) · Molecular Immunology · doi:10.1016/j.molimm.2017.12.003 · Cited by 59 · see citing works
Turning enemies into allies—reprogramming tumor-associated macrophages for cancer therapy
Molgora, M., & Colonna, M. (2021) · Med · doi:10.1016/j.medj.2021.05.001 · Cited by 56 · see citing works
Dixit, A. K., Sarver, A. G., Zettervall, J., Huang, H., Zheng, K., Brekken, R. A., & Provenzano, P. P. (2022) · JCI Insight · doi:10.1172/jci.insight.153242 · Cited by 57 · see citing works
cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer
Kabashima, A., Matsuo, Y., Ito, S., Akiyama, Y., Ishii, T., Shimada, S., Masamune, A., Tanabe, M., & Tanaka, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-14297-5 · Cited by 55 · see citing works
Komohara, Y., Kurotaki, D., Tsukamoto, H., Miyasato, Y., Yano, H., Pan, C., Yamamoto, Y., & Fujiwara, Y. (2023) · Cancer Science · doi:10.1111/cas.15751 · Cited by 53 · see citing works
Shen, H., Liu, J., Chen, S., Ma, X., Ying, Y., Li, J., Wang, W., Wang, X., & Xie, L. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.657318 · Cited by 53 · see citing works
A bi-directional dialog between vascular cells and monocytes/macrophages regulates tumor progression
Delprat, V., & Michiels, C. (2021) · Cancer and Metastasis Reviews · doi:10.1007/s10555-021-09958-2 · Cited by 51 · see citing works
Prolactin promotes fibrosis and pancreatic cancer progression
Tandon, M., Coudriet, G. M., Criscimanna, A., Socorro, M., Eliliwi, M., Singhi, A., Cruz-Monserrate, Z., Bailey, P., Lotze, M., Zeh, H., et al. (2019) · Cancer Research · doi:10.1158/0008-5472.can-18-3064 · Cited by 43 · see citing works
Microbiota in cancer: molecular mechanisms and therapeutic interventions
Chen, Z., Guan, D., Wang, Z., Li, X., Dong, S., Huang, J., & Zhou, W. (2023) · MedComm · doi:10.1002/mco2.417 · Cited by 46 · see citing works
Bao, X., Li, Q., Chen, D., Dai, X., Liu, C., Tian, W., Zhang, H., Jin, Y., Wang, Y., Cheng, J., et al. (2024) · Cell Reports Medicine · doi:10.1016/j.xcrm.2024.101399 · Cited by 46 · see citing works
Zhao, C.-C., Han, Q.-J., Ying, H.-Y., Gu, X.-X., Yang, N., Li, L.-Y., & Zhang, Q.-Z. (2022) · OncoImmunology · doi:10.1080/2162402x.2022.2032918 · Cited by 43 · see citing works
Association of the Microbiota and Pancreatic Cancer: Opportunities and Limitations
Chen, Z., Zhang, S., Dong, S., Xu, H. M., & Zhou, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.844401 · Cited by 45 · see citing works
Gata6+ resident peritoneal macrophages promote the growth of liver metastasis
Hossain, M., Shim, R., Lee, W., Sharpe, A. H., & Kubes, P. (2022) · Nature Communications · doi:10.1038/s41467-022-32080-y · Cited by 42 · see citing works
Macrophages in tumor cell migration and metastasis
Friedman, M., Karagiannis, G. S., Condeelis, J. S., Oktay, M. H., & Entenberg, D. R. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1494462 · Cited by 44 · see citing works
The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates
Mohamed, E. T., Al-Khami, A. A., & Rodrı́guez, P. C. (2018) · Cellular and Molecular Immunology · doi:10.1038/s41423-018-0001-7 · Cited by 39 · see citing works
Mirage or long-awaited oasis: reinvigorating T-cell responses in pancreatic cancer
Ware, M. B., El‐Rayes, B. F., & Lesinski, G. B. (2020) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2020-001100 · Cited by 32 · see citing works
Tumor Microenvironment in Pancreatic Intraepithelial Neoplasia
Opitz, F. V., Häberle, L., Daum, A., & Esposito, I. (2021) · Cancers · doi:10.3390/cancers13246188 · Cited by 30 · see citing works
βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer
Bachy, S., Wu, Z., Gamradt, P., Thierry, K., Milani, P., Chlasta, J., & Hennino, A. (2022) · iScience · doi:10.1016/j.isci.2022.103758 · Cited by 31 · see citing works
Noncoding RNA-mediated macrophage and cancer cell crosstalk in hepatocellular carcinoma
Zhou, Z., Wang, Z., Gao, J., Lin, Z., Wang, Y., Shan, P., Li, M., Zhou, T., & Li, P. (2022) · Molecular Therapy — Oncolytics · doi:10.1016/j.omto.2022.03.002 · Cited by 32 · see citing works
Graziano, V., Dannhorn, A., Hulme, H., Williamson, K., Buckley, H., Karim, S. A., Wilson, M., Lee, S. Y., Kaistha, B. P., Islam, S., et al. (2023) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-006457 · Cited by 29 · see citing works
Repolarization of Unbalanced Macrophages: Unmet Medical Need in Chronic Inflammation and Cancer
Degboé, Y., Poupot, R., & Poupot, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031496 · Cited by 32 · see citing works
Qin, H., Xiao, A., Lu, Q., Li, Y., Luo, X., Zheng, E., Tian, C., Liu, H., Zheng, X., Li, W., et al. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.10.006 · Cited by 29 · see citing works
Ibrahim, A. M., Moss, M. A., Gray, Z., Rojo, M. D., Burke, C. M., Schwertfeger, K. L., dos Santos, C. O., & Machado, H. L. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.569985 · Cited by 29 · see citing works
Unravelling monocyte functions: from the guardians of health to the regulators of disease
Mildner, A., Kim, K.-W., & Yona, S. (2024) · Discovery Immunology · doi:10.1093/discim/kyae014 · Cited by 31 · see citing works
Self-citationShi, J., Lu, P., Shen, W., He, R., Yang, M., Fang, Y., Sun, Y., Niu, N., & Xue, J. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.03.051 · Cited by 28 · see citing works
- Authors
- Zhu, Y., Herndon, J. M., Sojka, D. K., Kim, K.-W., Knolhoff, B. L., Zuo, C., Cullinan, D. R., Luo, J., Bearden, A. R., Lavine, K. J., Yokoyama, W. M., Hawkins, W. G., Fields, R. C., Randolph, G. J., & DeNardo, D. G.
- Corresponding author
- DeNardo, David G.
- ORCID
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2017-09
- Volume
- 47
- Issue
- 3
- Pages
- 597
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W3154781712
- Cited by
- 180
- References
- 0
- Citations by year
- 2026: 12 · 2025: 20 · 2024: 16 · 2023: 11 · 2022: 24 · 2021: 34 · 2020: 30 · 2019: 20 · 2018: 10 · 2017: 3
- FWCI
- 7.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Immunity (publishedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL138466, K08HL123519)
- National Cancer Institute (R01CA177670, R01CA203890, T32CA009621)
- National Institute of Allergy and Infectious Diseases (R01AI049653)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
- Health Sciences › Medicine › Oncology › Cancer Cells and Metastasis
- Keywords
- tissue-resident macrophages, pancreatic ductal adenocarcinoma, embryonic hematopoiesis, tumor-associated macrophages, macrophage origin, tumor progression, tumor fibrosis, macrophage proliferation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review