Kaeser, Pascal S.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., et al. (2019) · Neuron

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 938

RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction

Kaeser, P. S., Deng, L., Wang, Y., Dulubova, I., Liu, X., Rizo, J., & Südhof, T. C. (2011) · Cell

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 607

Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

Saka, S. K., Wang, Y., Kishi, J. Y., Zhu, A., Zeng, Y., Xie, W., Kirli, K., Yapp, C., Cicconet, M., Beliveau, B. J., et al. (2018) · Nature Biotechnology

Advanced biosensing and bioanalysis techniquesAdvanced Fluorescence Microscopy Techniques

Cited by 485

Molecular Mechanisms for Synchronous, Asynchronous, and Spontaneous Neurotransmitter Release

Kaeser, P. S., & Regehr, W. G. (2014) · Annual Review of Physiology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 447

RIM determines Ca2+ channel density and vesicle docking at the presynaptic active zone

Han, Y., Kaeser, P. S., Südhof, T. C., & Schneggenburger, R. (2011) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 354

Transcellular Nanoalignment of Synaptic Function

Biederer, T., Kaeser, P. S., & Blanpied, T. A. (2017) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 352

RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13

Deng, L., Kaeser, P. S., Xu, W., & Südhof, T. C. (2011) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 287

Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1α

Chevaleyre, V., Heifets, B. D., Kaeser, P. S., Südhof, T. C., & Castillo, P. E. (2007) · Neuron

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 261

The readily releasable pool of synaptic vesicles

Kaeser, P. S., & Regehr, W. G. (2017) · Current Opinion in Neurobiology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 231

An action potential initiation mechanism in distal axons for the control of dopamine release

Liu, C., Cai, X., Ritzau-Jost, A., Kramer, P. F., Li, Y., Khaliq, Z. M., Hallermann, S., & Kaeser, P. S. (2022) · Science

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 213

Sensory-Related Neural Activity Regulates the Structure of Vascular Networks in the Cerebral Cortex

Lacoste, B., Comin, C. H., Ben-Zvi, A., Kaeser, P. S., Xu, X., Costa, L. D. F., & Gu, C. (2014) · Neuron

Barrier Structure and Function StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 171

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

Wang, S. S. H., Held, R. G., Wong, M. Y., Liu, C., Karakhanyan, A., & Kaeser, P. S. (2016) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 143

RIM genes differentially contribute to organizing presynaptic release sites

Kaeser, P. S., Deng, L., Fan, M., & Südhof, T. C. (2012) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 115

Assembly of the presynaptic active zone

Emperador-Melero, J., & Kaeser, P. S. (2020) · Current Opinion in Neurobiology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 109

ELKS2α/CAST deletion selectively increases neurotransmitter release at inhibitory synapses

Kaeser, P. S., Deng, L., Chávez, A. E., Liu, X., Castillo, P. E., & Südhof, T. C. (2009) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 102

Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning

Tsetsenis, T., Younts, T. J., Chiu, C. Q., Kaeser, P. S., Castillo, P. E., & Südhof, T. C. (2011) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 81

RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning

Kaeser, P. S., Kwon, H.-B., Blundell, J., Chevaleyre, V., Morishita, W., Malenka, R. C., Powell, C. M., Castillo, P. E., & Südhof, T. C. (2008) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 74

Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation

Huang, Y.-Y., Zakharenko, S. S., Schoch, S., Kaeser, P. S., Janz, R., Südhof, T. C., Siegelbaum, S. A., & Kandel, E. R. (2005) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 65

Molecular and functional architecture of striatal dopamine release sites

Banerjee, A., Imig, C., Balakrishnan, K., Kershberg, L., Lipstein, N., Uronen, R.-L., Wang, J., Cai, X., Benseler, F., Rhee, J. S., et al. (2022) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 58

ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones

Kawabe, H., Mitkovski, M., Kaeser, P. S., Hirrlinger, J., Opazo, F., Nestvogel, D., Kalla, S., Fejtova, A., Verrier, S. E., Bungers, S. R., et al. (2017) · Journal of Cell Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 50

Rebuilding essential active zone functions within a synapse

Tan, C., Wang, S. S. H., de Nola, G., & Kaeser, P. S. (2022) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 40

Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses

Emperador-Melero, J., Andersen, J. W., Metzbower, S. R., Levy, A. D., Dharmasri, P. A., de Nola, G., Blanpied, T. A., & Kaeser, P. S. (2024) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 27

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

Tan, C., de Nola, G., Qiao, C., Imig, C., Born, R. T., Brose, N., & Kaeser, P. S. (2022) · eLife

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 17