Assembly of the presynaptic active zone

The Presynaptic Active Zone

Südhof, T. C. (2012) · Neuron · doi:10.1016/j.neuron.2012.06.012 · Cited by 1,062 · see citing works

Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits

Südhof, T. C. (2017) · Cell · doi:10.1016/j.cell.2017.10.024 · Cited by 810 · see citing works

Bruchpilot Promotes Active Zone Assembly, Ca ²⁺ Channel Clustering, and Vesicle Release

Kittel, R. J., Wichmann, C., Rasse, T. M., Fouquet, W., Schmidt, M., Schmid, A., Wagh, D. A., Pawlu, C., Kellner, R. R., Willig, K. I., et al. (2006) · Science · doi:10.1126/science.1126308 · Cited by 772 · see citing works

Superresolution Imaging of Chemical Synapses in the Brain

Dani, A., Huang, B., Bergan, J. F., Dulac, C. G., & Zhuang, X. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.021 · Cited by 718 · see citing works

A trans-synaptic nanocolumn aligns neurotransmitter release to receptors

Tang, A.-H., Chen, H., Li, T. P., Metzbower, S. R., MacGillavry, H. D., & Blanpied, T. A. (2016) · Nature · doi:10.1038/nature19058 · Cited by 677 · see citing works

UNC-13 is required for synaptic vesicle fusion in C. elegans

Richmond, J. E., Davis, W. S., & Jørgensen, E. M. (1999) · Nature Neuroscience · doi:10.1038/14755 · Cited by 617 · see citing works

Membrane protein sequestering by ionic protein–lipid interactions

van den Bogaart, G., Meyenberg, K., Risselada, H. J., Amin, H., Willig, K. I., Hubrich, B. E., Dier, M., Hell, S. W., Grubmüller, H., Diederichsen, U., et al. (2011) · Nature · doi:10.1038/nature10545 · Cited by 617 · see citing works

RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction

Kaeser, P. S., Deng, L., Wang, Y., Dulubova, I., Liu, X., Rizo, J., & Südhof, T. C. (2011) · Cell · doi:10.1016/j.cell.2010.12.029 · Cited by 607 · see citing works

Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

Zeng, M., Shang, Y., Araki, Y., Guo, T., Huganir, R. L., & Zhang, M. (2016) · Cell · doi:10.1016/j.cell.2016.07.008 · Cited by 598 · see citing works

Assembly of presynaptic active zones from cytoplasmic transport packets

Ahmari, S. E., Buchanan, J., & Smith, S. J. (2000) · Nature Neuroscience · doi:10.1038/74814 · Cited by 596 · see citing works

A liquid phase of synapsin and lipid vesicles

Milovanović, D., Wu, Y., Bian, X., & Camilli, P. V. D. (2018) · Science · doi:10.1126/science.aat5671 · Cited by 494 · see citing works

Maturation of active zone assembly by Drosophila Bruchpilot

Fouquet, W., Owald, D., Wichmann, C., Mertel, S., Depner, H., Dyba, M., Hallermann, S., Kittel, R. J., Eimer, S., & Sigrist, S. J. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200812150 · Cited by 396 · see citing works

The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones

Imig, C., Min, S.-W., Krinner, S., Arancillo, M., Rosenmund, C., Südhof, T. C., Rhee, J., Brose, N., & Cooper, B. H. (2014) · Neuron · doi:10.1016/j.neuron.2014.10.009 · Cited by 389 · see citing works

The architecture of active zone material at the frog's neuromuscular junction

Harlow, M. L., Ress, D., Stoschek, A., Marshall, R. M., & McMahan, U. J. (2001) · Nature · doi:10.1038/35054000 · Cited by 388 · see citing works

The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans

Zhen, M., & Jin, Y. (1999) · Nature · doi:10.1038/43886 · Cited by 374 · see citing works

Unitary Assembly of Presynaptic Active Zones from Piccolo-Bassoon Transport Vesicles

Shapira, M., Zhai, R. G., Dresbach, T., Bresler, T., Torres, V. I., Gundelfinger, E. D., Ziv, N. E., & Garner, C. C. (2003) · Neuron · doi:10.1016/s0896-6273(03)00207-1 · Cited by 354 · see citing works

Transcellular Nanoalignment of Synaptic Function

Biederer, T., Kaeser, P. S., & Blanpied, T. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.10.006 · Cited by 352 · see citing works

Drosophila Unc-13 is essential for synaptic transmission

Aravamudan, B., Fergestad, T., Davis, W. S., Rodesch, C. K., & Broadie, K. S. (1999) · Nature Neuroscience · doi:10.1038/14764 · Cited by 335 · see citing works

A post-docking role for active zone protein Rim

Koushika, S. P., Richmond, J. E., Hadwiger, G., Weimer, R. M., Jørgensen, E. M., & Nonet, M. L. (2001) · Nature Neuroscience · doi:10.1038/nn732 · Cited by 320 · see citing works

RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release

Liu, K. S. Y., Siebert, M., Mertel, S., Knoche, E., Wegener, S., Wichmann, C., Matkovic, T., Muhammad, K., Depner, H., Mettke, C., et al. (2011) · Science · doi:10.1126/science.1212991 · Cited by 306 · see citing works

Drosophila Liprin-α and the Receptor Phosphatase Dlar Control Synapse Morphogenesis

Kaufmann, N., DeProto, J., Ranjan, R., Wan, H., & Vactor, D. V. (2002) · Neuron · doi:10.1016/s0896-6273(02)00643-8 · Cited by 302 · see citing works

RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13

Deng, L., Kaeser, P. S., Xu, W., & Südhof, T. C. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.005 · Cited by 287 · see citing works

Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites

Liu, C., Kershberg, L., Wang, J., Schneeberger, S., & Kaeser, P. S. (2018) · Cell · doi:10.1016/j.cell.2018.01.008 · Cited by 249 · see citing works

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

Shin, O.-H., Lu, J., Rhee, J.-S., Tomchick, D. R., Pang, Z. P., Wojcik, S. M., Camacho-Perez, M., Brose, N., Machius, M., Rizo, J., et al. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1758 · Cited by 243 · see citing works

Synaptic weight set by Munc13-1 supramolecular assemblies

Sakamoto, H., Ariyoshi, T., Kimpara, N., Sugao, K., Taiko, I., Takikawa, K., Asanuma, D., Namiki, S., & Hirose, K. (2018) · Nature Neuroscience · doi:10.1038/s41593-017-0041-9 · Cited by 235 · see citing works

Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling

Böhme, M. A., Beis, C., Reddy‐Alla, S., Reynolds, E., Mampell, M. M., Grasskamp, A. T., Lützkendorf, J., Bergeron, D. D., Driller, J. H., Babikir, H. A., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4364 · Cited by 221 · see citing works

SYD-2 Liprin-α organizes presynaptic active zone formation through ELKS

Dai, Y., Taru, H., Deken, S. L., Grill, B., Ackley, B., Nonet, M. L., & Jin, Y. (2006) · Nature Neuroscience · doi:10.1038/nn1808 · Cited by 218 · see citing works

RIM and RIM-BP Form Presynaptic Active-Zone-like Condensates via Phase Separation.

Wu, X., Cai, Q., Shen, Z., Chen, X., Zeng, M.-L., Du, S.-W., & Zhang, M.-J. (2019) · Molecules and Cells · doi:10.1016/j.molcel.2018.12.007 · Cited by 216 · see citing works

Association of the Kinesin Motor KIF1A with the Multimodular Protein Liprin-α

Shin, H., Wyszynski, M. W., Huh, K. H., Valtschanoff, J. G., Lee, J.-R., Ko, J., Streuli, M., Weinberg, R. J., Sheng, M., & Kim, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211874200 · Cited by 207 · see citing works

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

Pulido, R., Serra‐Pages, C., Tang, M. H. Y., & Streuli, M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11686 · Cited by 207 · see citing works

[Synaptic vesicles and pouches at the level of "active zones" of the neuromuscular junction].

Couteaux, R., & Pécot-Dechavassine, M. (1970) · PubMed · Cited by 202 · see citing works

Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis

Mukherjee, K., Yang, X., Gerber, S. H., Kwon, H.-B., Ho, A., Castillo, P. E., Liu, X., & Südhof, T. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002307107 · Cited by 195 · see citing works

Bassoon Specifically Controls Presynaptic P/Q-type Ca2+ Channels via RIM-Binding Protein

Davydova, D., Marini, C., King, C., Klueva, J., Bischof, F., Romorini, S., Montenegro‐Venegas, C., Heine, M., Schneider, R., Schröder, M. S., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.012 · Cited by 172 · see citing works

Neuropeptide Delivery to Synapses by Long-Range Vesicle Circulation and Sporadic Capture

Wong, M. Y., Zhou, C., Shakiryanova, D. M., Lloyd, T. E., Deitcher, D. L., & Levitan, E. S. (2012) · Cell · doi:10.1016/j.cell.2011.12.036 · Cited by 164 · see citing works

Direct Observation Demonstrates that Liprin-α Is Required for Trafficking of Synaptic Vesicles

Miller, K. E., DeProto, J., Kaufmann, N., Patel, B. N., Duckworth, A. M., & Vactor, D. V. (2005) · Current Biology · doi:10.1016/j.cub.2005.02.061 · Cited by 155 · see citing works

How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs

Acuna, C., Liu, X., & Südhof, T. C. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.042 · Cited by 154 · see citing works

Kinesin-3 responds to local microtubule dynamics to target synaptic cargo delivery to the presynapse

Guedes-Dias, P., Nirschl, J. J., Abreu, N., Tokito, M. K., Janke, C., Magiera, M. M., & Holzbaur, E. L. F. (2019) · Current Biology · doi:10.1016/j.cub.2018.11.065 · Cited by 153 · see citing works

How to make a synaptic ribbon: RIBEYE deletion abolishes ribbons in retinal synapses and disrupts neurotransmitter release

Maxeiner, S., Luo, F., Tan, A., Schmitz, F., & Südhof, T. C. (2016) · The EMBO Journal · doi:10.15252/embj.201592701 · Cited by 153 · see citing works

The Balance between Capture and Dissociation of Presynaptic Proteins Controls the Spatial Distribution of Synapses

Wu, Y., Huo, L., Maeder, C. I., Feng, W., & Shen, K. (2013) · Neuron · doi:10.1016/j.neuron.2013.04.035 · Cited by 144 · see citing works

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

Wang, S. S. H., Held, R. G., Wong, M. Y., Liu, C., Karakhanyan, A., & Kaeser, P. S. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.005 · Cited by 143 · see citing works

Stable Positioning of Unc13 Restricts Synaptic Vesicle Fusion to Defined Release Sites to Promote Synchronous Neurotransmission

Reddy‐Alla, S., Böhme, M. A., Reynolds, E., Beis, C., Grasskamp, A. T., Mampell, M. M., Maglione, M., Jusyte, M., Rey, U., Babikir, H. A., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.08.016 · Cited by 141 · see citing works

Distinct Nanoscale Calcium Channel and Synaptic Vesicle Topographies Contribute to the Diversity of Synaptic Function

Rebola, N., Reva, M., Kirizs, T., Szoboszlay, M., Lőrincz, A., Moneron, G., Nusser, Z., & DiGregorio, D. A. (2019) · Neuron · doi:10.1016/j.neuron.2019.08.014 · Cited by 136 · see citing works

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles

Vukoja, A., Rey, U., Petzoldt, A. G., Ott, C., Vollweiter, D., Quentin, C., Puchkov, D., Reynolds, E., Lehmann, M., Hohensee, S., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.08.004 · Cited by 133 · see citing works

An Arf-like Small G Protein, ARL-8, Promotes the Axonal Transport of Presynaptic Cargoes by Suppressing Vesicle Aggregation

Klassen, M. P., Wu, Y., Maeder, C. I., Nakae, I., Cueva, J. G., Lehrman, E. K., Tada, M., Gengyo‐Ando, K., Wang, G. J., Goodman, M. B., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.04.033 · Cited by 124 · see citing works

Presynaptic α2δ-3 is required for synaptic morphogenesis independent of its Ca2+ - channel functions

Kurshan, P. T., Oztan, A., & Schwarz, T. (2009) · Nature Neuroscience · doi:10.1038/nn.2417 · Cited by 119 · see citing works

The Two Isoforms of the<i>Caenorhabditis elegans</i>Leukocyte-Common Antigen Related Receptor Tyrosine Phosphatase PTP-3 Function Independently in Axon Guidance and Synapse Formation

Ackley, B. D., Harrington, R. J., Hudson, M. L., Williams, L., Kenyon, C. J., Chisholm, A. D., & Jin, Y. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2010-05.2005 · Cited by 113 · see citing works

Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters

Trotter, J. H., Hao, J., Maxeiner, S., Tsetsenis, T., Liu, Z., Zhuang, X., & Südhof, T. C. (2019) · The Journal of Cell Biology · doi:10.1083/jcb.201812076 · Cited by 112 · see citing works

Formation of Golgi-Derived Active Zone Precursor Vesicles

Maas, C., Torres, V. I., Altrock, W. D., Leal‐Ortiz, S., Wagh, D. A., Terry-Lorenzo, R. T., Fejtová, A., Gundelfinger, E. D., Ziv, N. E., & Garner, C. C. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0195-12.2012 · Cited by 103 · see citing works

Calcium Channels Link the Muscle-Derived Synapse Organizer Laminin β2 to Bassoon and CAST/Erc2 to Organize Presynaptic Active Zones

Chen, J., Billings, S. E., & Nishimune, H. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3771-10.2011 · Cited by 94 · see citing works

Spatiotemporal Regulation of Synaptic Vesicle Fusion Sites in Central Synapses

Maschi, D., & Klyachko, V. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.03.006 · Cited by 86 · see citing works

Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses

Wong, M. Y., Liu, C., Wang, S. S. H., Roquas, A. C. F., Fowler, S. C., & Kaeser, P. S. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1719012115 · Cited by 77 · see citing works

Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release

Zhao, X., Manning, L., Nelson, J. C., Richmond, J. E., Colón‐Ramos, D. A., Shen, K., & Kurshan, P. T. (2017) · eLife · doi:10.7554/elife.29276 · Cited by 74 · see citing works

The Active Zone Protein Family ELKS Supports Ca2+Influx at Nerve Terminals of Inhibitory Hippocampal Neurons

Liu, C., Bickford, L. S., Held, R. G., Nyitrai, H., Südhof, T. C., & Kaeser, P. S. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0999-14.2014 · Cited by 73 · see citing works

Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels

Lv, C., Stewart, W. J., Akanyeti, O., Frederick, C., Zhu, J., Santos‐Sacchi, J., Sheets, L., Liao, J. C., & Zenisek, D. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.045 · Cited by 71 · see citing works

ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains

Held, R. G., Liu, C., & Kaeser, P. S. (2016) · eLife · doi:10.7554/elife.14862 · Cited by 67 · see citing works

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses

Sclip, A., & Südhof, T. C. (2020) · eLife · doi:10.7554/elife.53406 · Cited by 60 · see citing works

Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi

Emperador-Melero, J., Huson, V., van Weering, J. R. T., Bollmann, C., von Mollard, G. F., Toonen, R. F. G., & Verhage, M. (2018) · Nature Communications · doi:10.1038/s41467-018-05699-z · Cited by 59 · see citing works

RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes

de Jong, A. P. H., Roggero, C. M., Ho, M., Wong, M. Y., Brautigam, C. A., Rizo, J., & Kaeser, P. S. (2018) · Neuron · doi:10.1016/j.neuron.2018.03.011 · Cited by 59 · see citing works

Liprin-α is required for photoreceptor target selection in Drosophila

Choe, K., Prakash, S., Bright, A., & Clandinin, T. R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601185103 · Cited by 59 · see citing works

CaV2.1 α1 Subunit Expression Regulates Presynaptic CaV2.1 Abundance and Synaptic Strength at a Central Synapse

Lübbert, M., Goral, R. O., Keine, C., Thomas, C. I., Guerrero‐Given, D., Putzke, T., Satterfield, R., Kamasawa, N., & Young, S. (2018) · Neuron · doi:10.1016/j.neuron.2018.11.028 · Cited by 58 · see citing works

Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release

Bruckner, J. J., Zhan, H., Gratz, S., Rao, M., Ukken, F. P., Zilberg, G., & O'Connor-Giles, K. M. (2017) · Journal of Cell Biology · doi:10.1083/jcb.201601098 · Cited by 55 · see citing works

RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses

Brockmann, M. M., Maglione, M., Willmes, C., Stumpf, A., Bouazza, B. A., Velasquez, L. M., Grauel, M., Beed, P., Lehmann, M., Gimber, N., et al. (2018) · bioRxiv · doi:10.7554/elife.43243 · Cited by 53 · see citing works

PTPσ Drives Excitatory Presynaptic Assembly via Various Extracellular and Intracellular Mechanisms

Han, K. A., Ko, J. S., Pramanik, G., Kim, J. Y., Tabuchi, K., Um, J. W., & Ko, J. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0672-18.2018 · Cited by 51 · see citing works

ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones

Kawabe, H., Mitkovski, M., Kaeser, P. S., Hirrlinger, J., Opazo, F., Nestvogel, D., Kalla, S., Fejtova, A., Verrier, S. E., Bungers, S. R., et al. (2017) · Journal of Cell Biology · doi:10.1083/jcb.201606086 · Cited by 50 · see citing works

Complex interactions amongst N-cadherin, DLAR, and Liprin-α regulate Drosophila photoreceptor axon targeting

Prakash, S., McLendon, H. M., Dubreuil, C., Ghose, A., Hwa, J. J., Dennehy, K. A., Tomalty, K. M. H., Clark, K., Vactor, D. V., & Clandinin, T. R. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.09.016 · Cited by 44 · see citing works

The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival

Maeder, C. I., Kim, J., Liang, X., Kaganovsky, K., Shen, A., Li, Q., Li, Z., Wang, S., Xu, X. Z. S., Li, J. B., et al. (2018) · Cell · doi:10.1016/j.cell.2018.07.046 · Cited by 43 · see citing works

RIMB-1/RIM-Binding Protein and UNC-10/RIM Redundantly Regulate Presynaptic Localization of the Voltage-Gated Calcium Channel in Caenorhabditis elegans

Kushibiki, Y., Suzuki, T., Jin, Y.-S., & Taru, H. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.0506-19.2019 · Cited by 41 · see citing works

Mechanisms of PTPσ-Mediated Presynaptic Differentiation

Bomkamp, C., Padmanabhan, N., Karimi, B., Ge, Y., Chao, J. T., Loewen, C. J. R., Siddiqui, T. J., & Craig, A. M. (2019) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2019.00017 · Cited by 31 · see citing works

Synaptic fine structure.

Akert, K., Moor, H., & Pfenninger, K. H. (1971) · PubMed · Cited by 29 · see citing works

DIRECT INTERACTIONS BETWEEN C. ELEGANS RAB-3 AND RIM PROVIDE A MECHANISM TO TARGET VESICLES TO THE PRESYNAPTIC DENSITY

Gracheva, E. O., Hadwiger, G., Nonet, M., & Richmond, J. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.08.026 · Cited by 1 · see citing works

The cell biology of synapse formation

Südhof, T. C. (2021) · Journal of Cell Biology · doi:10.1083/jcb.202103052 · Cited by 358 · see citing works

Selective motor activation in organelle transport along axons

Cason, S. E., & Holzbaur, E. L. F. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00491-w · Cited by 169 · see citing works

Vesicle Tethering on the Surface of Phase-Separated Active Zone Condensates

Wu, X., Ganzella, M., Zhou, J., Zhu, S., Jahn, R., & Zhang, M. (2020) · Molecular Cell · doi:10.1016/j.molcel.2020.10.029 · Cited by 119 · see citing works

Mechanisms of neuromodulatory volume transmission

Özçete, Ö. D., Banerjee, A., & Kaeser, P. S. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02608-3 · Cited by 123 · see citing works

PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure

Emperador-Melero, J., Wong, M. Y., Wang, S. S. H., de Nola, G., Nyitrai, H., Kirchhausen, T. L., & Kaeser, P. S. (2021) · Nature Communications · doi:10.1038/s41467-021-23116-w · Cited by 104 · see citing works

Short-distance vesicle transport via phase separation

Qiu, H., Wu, X., Ma, X., Li, S., Cai, Q., Ganzella, M., Ge, L., Zhang, H., & Zhang, M. (2024) · Cell · doi:10.1016/j.cell.2024.03.003 · Cited by 86 · see citing works

A Presynaptic Perspective on Transport and Assembly Mechanisms for Synapse Formation

Rizalar, F. S., Roosen, D. A., & Haucke, V. (2020) · Neuron · doi:10.1016/j.neuron.2020.09.038 · Cited by 63 · see citing works

Molecular and functional architecture of striatal dopamine release sites

Banerjee, A., Imig, C., Balakrishnan, K., Kershberg, L., Lipstein, N., Uronen, R.-L., Wang, J., Cai, X., Benseler, F., Rhee, J. S., et al. (2022) · Neuron · doi:10.1016/j.neuron.2021.10.028 · Cited by 58 · see citing works

Oligomerized Liprin-α Promotes Phase Separation of ELKS for Compartmentalization of Presynaptic Active Zone Proteins

Liang, M., Jin, G., Xie, X., Zhang, W., Li, K., Niu, F., Yu, C., & Wei, Z. (2020) · Cell Reports · doi:10.1016/j.celrep.2021.108901 · Cited by 54 · see citing works

Synaptic vesicle proteins and ATG9A self-organize in distinct vesicle phases within synapsin condensates

Park, D., Wu, Y., Wang, X., Gowrishankar, S., Baublis, A., & Camilli, P. V. D. (2023) · Nature Communications · doi:10.1038/s41467-023-36081-3 · Cited by 53 · see citing works

ELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals

Nyitrai, H., Wang, S. S. H., & Kaeser, P. S. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107712 · Cited by 49 · see citing works

Rebuilding essential active zone functions within a synapse

Tan, C., Wang, S. S. H., de Nola, G., & Kaeser, P. S. (2022) · Neuron · doi:10.1016/j.neuron.2022.01.026 · Cited by 40 · see citing works

Extracellular matrix and synapse formation

Yang, L., Wei, M., Xing, B., & Zhang, C. (2022) · Bioscience Reports · doi:10.1042/bsr20212411 · Cited by 40 · see citing works

Reconstitution of synaptic junctions orchestrated by teneurin-latrophilin complexes

Zhang, X., Chen, X., Matúš, D., & Südhof, T. C. (2025) · Science · doi:10.1126/science.adq3586 · Cited by 37 · see citing works

Neuronal biomolecular condensates and their implications in neurodegenerative diseases

Nam, J., & Gwon, Y. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1145420 · Cited by 32 · see citing works

Liprin-α proteins are master regulators of human presynapse assembly

de la Cruz, B. M., Campos, J., Molinaro, A., Xie, X., Jin, G., Wei, Z., Acuna, C., & Sterky, F. H. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01592-9 · Cited by 32 · see citing works

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR

Emperador-Melero, J., de Nola, G., & Kaeser, P. S. (2021) · eLife · doi:10.7554/elife.66638 · Cited by 29 · see citing works

UNC-2 CaV2 Channel Localization at Presynaptic Active Zones Depends on UNC-10/RIM and SYD-2/Liprin-α in Caenorhabditis elegans

Oh, K. H., Krout, M., Richmond, J. E., & Kim, H. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0076-21.2021 · Cited by 28 · see citing works

Presynaptic perspective: Axonal transport defects in neurodevelopmental disorders

Xiong, G.-J., & Sheng, Z. (2024) · The Journal of Cell Biology · doi:10.1083/jcb.202401145 · Cited by 26 · see citing works

Interactions between Membraneless Condensates and Membranous Organelles at the Presynapse: A Phase Separation View of Synaptic Vesicle Cycle

Wu, X., Qiu, H., & Zhang, M. (2022) · Journal of Molecular Biology · doi:10.1016/j.jmb.2022.167629 · Cited by 28 · see citing works

Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses

Emperador-Melero, J., Andersen, J. W., Metzbower, S. R., Levy, A. D., Dharmasri, P. A., de Nola, G., Blanpied, T. A., & Kaeser, P. S. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01720-5 · Cited by 27 · see citing works

Mechanisms of Synaptic Vesicle Exo- and Endocytosis

Mochida, S. (2022) · Biomedicines · doi:10.3390/biomedicines10071593 · Cited by 27 · see citing works

Function of Drosophila Synaptotagmins in membrane trafficking at synapses

Quiñones-Frías, M. C., & Littleton, J. T. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03788-9 · Cited by 23 · see citing works

ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington’s disease

Cozzolino, F., Vezzoli, E., Cheroni, C., Besusso, D., Conforti, P., Valenza, M., Iacobucci, I., Monaco, V., Birolini, G., Bombaci, M., et al. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab047 · Cited by 23 · see citing works

Neuronal SNARE complex assembly guided by Munc18‐1 and Munc13‐1

Wang, S., & Ma, C. (2022) · FEBS Open Bio · doi:10.1002/2211-5463.13394 · Cited by 23 · see citing works

The role of RIM in neurotransmitter release: promotion of synaptic vesicle docking, priming, and fusion

Wu, S., Fan, J., Tang, F., Chen, L., Zhang, X., Xiao, D., & Li, X. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1123561 · Cited by 24 · see citing works

Synaptic recognition molecules in development and disease

Chowdhury, D., Watters, K. E., & Biederer, T. (2021) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2020.12.009 · Cited by 23 · see citing works

Liprin-α-Mediated Assemblies and Their Roles in Synapse Formation

Xie, X., Liang, M., Yu, C., & Wei, Z. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.653381 · Cited by 22 · see citing works

Protein composition of axonal dopamine release sites in the striatum

Kershberg, L., Banerjee, A., & Kaeser, P. S. (2022) · eLife · doi:10.7554/elife.83018 · Cited by 21 · see citing works

Beyond the MUN domain, Munc13 controls priming and depriming of synaptic vesicles

Leitz, J., Wang, C., Esquivies, L. R., Pfuetzner, R. A., Peters, J. J., Couoh‐Cardel, S., Wang, A. L., & Brünger, A. T. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114026 · Cited by 21 · see citing works

Complexin Membrane Interactions: Implications for Synapse Evolution and Function

Lottermoser, J. A., & Dittman, J. S. (2022) · Journal of Molecular Biology · doi:10.1016/j.jmb.2022.167774 · Cited by 18 · see citing works

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

Tan, C., de Nola, G., Qiao, C., Imig, C., Born, R. T., Brose, N., & Kaeser, P. S. (2022) · eLife · doi:10.7554/elife.79077 · Cited by 17 · see citing works

Finding functions of phase separation in the presynapse

McDonald, N. A., & Shen, K. (2021) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2021.04.001 · Cited by 14 · see citing works

Presynaptic bouton compartmentalization and postsynaptic density-mediated glutamate receptor clustering via phase separation

Feng, Z., Wu, X., & Zhang, M. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108622 · Cited by 16 · see citing works

Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons

Kim, O., Okamoto, Y., Kaufmann, W. A., Brose, N., Shigemoto, R., & Jonas, P. (2024) · PLOS Biology · doi:10.1371/journal.pbio.3002879 · Cited by 15 · see citing works

SAD-1 kinase controls presynaptic phase separation by relieving SYD-2/Liprin-α autoinhibition

McDonald, N. A., Tao, L., Dong, M., & Shen, K. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3002421 · Cited by 14 · see citing works

Membranes are functionalized by a proteolipid code

Kervin, T. A., & Overduin, M. (2024) · BMC Biology · doi:10.1186/s12915-024-01849-6 · Cited by 15 · see citing works

Ultrastructural analysis of wild-type and RIM1α knockout active zones in a large cortical synapse

Lichter, K., Paul, M. M., Pauli, M., Schoch, S., Kollmannsberger, P., Stigloher, C., Heckmann, M., & Sirén, A.-L. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111382 · Cited by 15 · see citing works

Diverse organization of voltage-gated calcium channels at presynaptic active zones

Zhang, W., Jiang, H.-H., & Luo, F. (2022) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2022.1023256 · Cited by 12 · see citing works

Presynaptic-like mechanisms and the control of insulin secretion in pancreatic β-cells.

Deng, K., & Thorn, P. (2022) · Cell Calcium · doi:10.1016/j.ceca.2022.102585 · Cited by 13 · see citing works

Phase Separation–Mediated Compartmentalization Underlies Synapse Formation and Plasticity

Wu, X., Shen, Z., & Zhang, M. (2025) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-112723-040159 · Cited by 14 · see citing works

Structural remodeling of target-SNARE protein complexes by NSF enables synaptic transmission

White, K. I., Khan, Y. A., Qiu, K., Balaji, A., Couoh‐Cardel, S., Esquivies, L. R., Pfuetzner, R. A., Diao, J., & Brünger, A. T. (2025) · Nature Communications · doi:10.1038/s41467-025-62764-0 · Cited by 11 · see citing works

Spatiotemporal organization and correlation of tip-focused exocytosis and endocytosis in regulating pollen tube tip growth

Weng, X., Shen, Y., Jiang, L., Zhao, L., & Wang, H. (2023) · Plant Science · doi:10.1016/j.plantsci.2023.111633 · Cited by 10 · see citing works

Synapse type-specific molecular nanoconfigurations of the presynaptic active zone in the hippocampus identified by systematic nanoscopyPreprint

Sakamoto, H., Kimpara, N., Namiki, S., Hamada, S., Ohtsuka, T., & Hirose, K. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.11.483942 · Cited by 15 · see citing works

On the targeting of voltage-gated calcium channels to neurotransmitter release sites

Chin, M., & Kaeser, P. S. (2024) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2024.102931 · Cited by 8 · see citing works

Tuning synapse strength by nanocolumn plasticity

Xu, N., Chen, S.-Y., & Tang, A. (2025) · Trends in Neurosciences · doi:10.1016/j.tins.2024.12.009 · Cited by 10 · see citing works

Bassoon, Presynaptic Scaffolding Protein: Narrative Review in Health and Disease

Kaladiyil, A. P., & Kukkle, P. L. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70066 · Cited by 9 · see citing works

SNARE Proteins in Synaptic Vesicle Fusion

Palfreyman, M. T., West, S. E., & Jørgensen, E. M. (2023) · Advances in neurobiology · doi:10.1007/978-3-031-34229-5_4 · Cited by 10 · see citing works

Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses

Lapios, P., Anger, R., Paget-Blanc, V., Marza, E., Lučić, V., Fronzes, R., Herzog, É., & Perrais, D. (2025) · Nature Communications · doi:10.1038/s41467-025-66355-x · Cited by 8 · see citing works

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels

Chin, M., & Kaeser, P. S. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114428 · Cited by 8 · see citing works

The role of selected postsynaptic scaffolding proteins at glutamatergic synapses in autism-related animal models

Melišková, V., Havránek, T., Bačová, Z., & Bakoš, J. (2021) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2004106 · Cited by 7 · see citing works

Stable and Flexible Synaptic Transmission Controlled by the Active Zone Protein Interactions

Mochida, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111775 · Cited by 7 · see citing works

Status epilepticus alters hippocampal ultrastructure in kainic acid rat model

Zhvania, M. G., Sharikadze, I., Japaridze, N. J., Tizabi, Y., Rzayev, F., Gasimov, E. K., & Lobzhanidze, G. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.102789 · Cited by 6 · see citing works

The liprin-α/RIM complex regulates the dynamic assembly of presynaptic active zones via liquid–liquid phase separation

Jin, G., Campos, J., Liu, Y., de la Cruz, B. M., Zhang, S., Liang, M., Li, K., Xie, X., Yu, C., Sterky, F. H., et al. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3002817 · Cited by 6 · see citing works

Vesicle choreographies keep up cell-to-extracellular matrix adhesion dynamics in polarized epithelial and endothelial cells

Villari, G., Gioelli, N., Valdembri, D., & Serini, G. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.08.003 · Cited by 6 · see citing works

Nanoscaled RIM clustering at presynaptic active zones revealed by endogenous tagging

Mrestani, A., Dannhäuser, S., Pauli, M., Kollmannsberger, P., Hübsch, M., Morris, L., Langenhan, T., Heckmann, M., & Paul, M. M. (2023) · Life Science Alliance · doi:10.26508/lsa.202302021 · Cited by 6 · see citing works

Sh3rf3 Deficiency drives autism-like behaviors via presynaptic dysfunction in mice

Yuan, Y., Li, Y., Yang, F., Jiang, Y., Ding, Y., Xiao, Y., Zhu, X., Shu, X., Huang, X., Wang, Y., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03370-w · Cited by 4 · see citing works

Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

Bell, C., Kilo, L., Gottschalk, D., Arian, J., Deneke, L., Kern, H. B., Rickert, C., Kobler, O., Strauß, J., Heine, M., et al. (2025) · eLife · doi:10.7554/elife.100394.3 · Cited by 4 · see citing works

Molecular definition of distinct active zone protein machineries for Ca 2+ channel clustering and synaptic vesicle primingPreprint

Emperador-Melero, J., Andersen, J. W., Metzbower, S. R., Levy, A. D., Dharmasri, P. A., de Nola, G., Blanpied, T. A., & Kaeser, P. S. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.27.564439 · Cited by 4 · see citing works

Distinctive characteristics of dopamine neuron release mechanisms: Insights into Parkinson’s Disease

Martino, E. D., Maduro, S., Luchicchi, A., Wilhelmus, M. M. M., & Orefice, N. S. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119534 · Cited by 3 · see citing works

DHCR24 deficiency causes AD-like pathology and cognitive decline via the cGAS-STING signaling pathway

Mengqi, Z., Wang, Z., Zhang, K., Yang, Y., Zu, H., Yuan, X.-S., & Wei, W. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.106150 · Cited by 2 · see citing works

The Liquid State of RIM1α and RBP Condensates is Maintained by Lipids

Fischer, C. M., Toprakcioglu, Z., de Csilléry, E., Schierle, G. S. K., & Knowles, T. P. J. (2025) · ACS Nano · doi:10.1021/acsnano.5c07661 · Cited by 2 · see citing works

Formation, Organization, and Maintenance of Synaptic Vesicle Pools: From Molecules to Structure and Dynamics

Chanaday, N. L. (2026) · Advances in neurobiology · doi:10.1007/978-3-032-12594-1_3 · Cited by 2 · see citing works

Organisation of the nervous system in cysts of the freshwater tardigrade Thulinius ruffoi (Parachela, Isohypsibioidea: Doryphoribiidae)

Janelt, K., & Poprawa, I. (2023) · Journal of Anatomy · doi:10.1111/joa.13994 · Cited by 2 · see citing works

A specific negatively charged sequence confers intramolecular regulation on Munc13-1 function in synaptic exocytosis

Zhao, K., Zhang, L., Lei, M., Jin, Z., Du, T., Zhang, H., Sheng, Y., Hu, Z., Wang, S., & Ma, C. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2508915122 · Cited by 1 · see citing works

Preface to the Special Issue “Presynaptic Dysfunction and Disease”

Smillie, K. J., Cousin, M. A., & Gordon, S. L. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15319 · Cited by 2 · see citing works

Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutonsPreprint

Kim, O., Okamoto, Y., Brose, N., Shigemoto, R., & Jónás, P. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.04.569907 · Cited by 2 · see citing works

Spatial proteomics reveals prefrontal circuit diversity in socioemotional behaviourPreprint

Ito, Y., Nagamoto, S., Uchiyama, S., Onishi, K., Matsubayashi, J., Fukuda, A., Funakoshi, M., Hattori, S., Takeuchi, K., Kudo, M., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.08.704617 · Cited by 2 · see citing works

Single-Molecule Localization Microscopy of Presynaptic Active Zones in Drosophila melanogaster after Rapid Cryofixation

Mrestani, A., Lichter, K., Sirén, A., Heckmann, M., Paul, M. M., & Pauli, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032128 · Cited by 1 · see citing works

Handshaking for ultrafast endocytosis: Dynamin1xA and Endophilin A1 sealed the deal

López-Begines, S., & Fernández‐Chacón, R. (2024) · The EMBO Journal · doi:10.1038/s44318-024-00179-1 · Cited by 1 · see citing works

Blobby is a synaptic active zone assembly protein required for memory in Drosophila

Lützkendorf, J., Matkovic, T., Liu, S., Götz, T., Gao, L., Turrel, O., Maglione, M., Grieger, M., Putignano, S., Ramesh, N., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55382-9 · Cited by 1 · see citing works

Submembrane liprin-α1 clusters spatially localize insulin granule fusion

Deng, K., Sun, K., Hallahan, N., Gan, W. J., Cielesh, M., Mahyad, B., Kebede, M. A., Larance, M., & Thorn, P. (2025) · The Journal of Cell Biology · doi:10.1083/jcb.202410210 · Cited by 1 · see citing works

Active Zone Maturation Controls Presynaptic Output and Release Mode and Is Regulated by Neuronal Activity

Akbergenova, Y., Matthias, J., Makeyeva, S., & Littleton, J. T. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1143-25.2025 · Cited by 7 · see citing works

CASKIN2 mediates PTPσ-orchestrated transsynaptic mechanisms at excitatory synapses

Han, K. A., Jang, G., Lee, H.-Y., Kim, B., Kanato, T., Vas, V., Buday, L., Liu, X., Choi, S.-Y., Um, J., et al. (2025) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2509116122 · Cited by 2 · see citing works

Genome-wide analysis reveals pathways important for the development and maturation of excitatory synaptic connections to GABAergic neurons

Oliver, D., Ramachandran, S., Biswas, K., Bénard, C. Y., Doitsidou, M., McKillop, H., Genao, N., Lemons, M. L., & Francis, M. M. (2026) · G3 Genes Genomes Genetics · doi:10.1093/g3journal/jkag028 · Cited by 2 · see citing works

Transcriptional and functional profiles of muscarinic receptor-expressing neurons in primate lateral prefrontal and anterior cingulate cortices

Tsolias, A., Mojica, C. A., Yamani, R., Khanna, S., Abdullatif, S. A., Snyder, B. J., Chang, W., Guillamón-Vivancos, T., Goodliffe, J. W., Capriglione, A. L., et al. (2026) · Communications Biology · doi:10.1038/s42003-026-09866-7 · Cited by 1 · see citing works

Munc13 serves as a molecular filter for SNARE sorting and assembly in active zone condensates

Zhang, H., Zhang, Y., Zhao, Z., Cao, Z., Zhao, K., Lei, M., Wang, S., & Ma, C. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2529572123 · Cited by 1 · see citing works

Presynaptic neurons self-tune by inversely coupling neurotransmitter release with the abundance of CaV2 voltage-gated Ca2+ channels

Xiong, A., Richmond, J. E., & Kim, H. (2024) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2404969121 · Cited by 3 · see citing works

All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation

Frankel, E. B., & Kurshan, P. T. (2020) · Neuron · doi:10.1016/j.neuron.2020.07.028 · Cited by 1 · see citing works

One domain to rule them all: “In synapse” reconstitution of core active zone functions

Chien, C., & Dickman, D. K. (2022) · Neuron · doi:10.1016/j.neuron.2022.04.004 · Cited by 1 · see citing works

Specific presynaptic functions require distinct Drosophila Cav2 splice isoformsPreprint

Bell, C., Kilo, L., Gottschalk, D., Arian, J., Deneke, L., Kern, H., Rickert, C., Kobler, O., Strauß, J., Heine, M., et al. (2024) · eLife · doi:10.7554/elife.100394 · Cited by 1 · see citing works

Reconstructing essential active zone functions within a synapsePreprint

Tan, C., Wang, S. S. H., de Nola, G., & Kaeser, P. S. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.11.21.469466

The intracellular C-terminus confers compartment-specific targeting of voltage-gated Ca 2+ channelsPreprint

Chin, M., & Kaeser, P. S. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.23.573183

Identification and characterization of a synaptic active zone assembly proteinPreprint

Lützkendorf, J., Matkovic, T., Götz, T., Liu, S., Ghelani, T., Maglione, M., Grieger, M., Putignano, S., Gao, L., Gimber, N., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.08.588536

Reviewer #3 (Public Review): Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

(2024) · eLife · doi:10.7554/elife.100394.1.sa1

Specific presynaptic functions require distinct Drosophila Cav2 splice isoformsPreprint

Bell, C., Kilo, L., Gottschalk, D., Kern, H., Arian, J., Deneke, L., Kobler, O., Rickert, C., Strauß, J., Heine, M., et al. (2024) · eLife · doi:10.7554/elife.100394.1

Reviewer #1 (Public Review): Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

(2024) · eLife · doi:10.7554/elife.100394.1.sa3

Author response: Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

Bell, C., Kilo, L., Gottschalk, D., Kern, H., Arian, J., Deneke, L., Kobler, O., Rickert, C., Strauß, J., Heine, M., et al. (2024) · eLife · doi:10.7554/elife.100394.1.sa0

eLife Assessment: Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

Dickman, D. K. (2024) · eLife · doi:10.7554/elife.100394.1.sa4

Reviewer #2 (Public Review): Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

(2024) · eLife · doi:10.7554/elife.100394.1.sa2

Specific presynaptic functions require distinct Drosophila Cav2 splice isoformsPreprint

Bell, C., Kilo, L., Gottschalk, D., Arian, J., Deneke, L., Kern, H. B., Rickert, C., Kobler, O., Strauß, J., Heine, M., et al. (2025) · eLife · doi:10.7554/elife.100394.2

PcloC ‐Mediated Phase Separation in Short‐Distance Vesicle Transport

Yan, H., & Deng, Y. (2024) · Traffic · doi:10.1111/tra.12959

Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release

Emperador-Melero, J., Signore, S. J. D., González, K. M. D. L., Kaeser, P. S., & Rodal, A. A. (2026) · eLife · doi:10.7554/elife.107276.3

Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked releasePreprint

Emperador-Melero, J., Signore, S. J. D., González, K. M. D. L., Kaeser, P. S., & Rodal, A. A. (2025) · eLife · doi:10.7554/elife.107276

Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked releasePreprint

Emperador-Melero, J., Signore, S. J. D., González, K. M. D. L., Kaeser, P. S., & Rodal, A. A. (2025) · eLife · doi:10.7554/elife.107276.1

Axonal dopamine release: Molecular mechanisms

Kaeser, P. S. (2025) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-443-29867-7.00004-9

KANK1 regulates the positioning of liprin-α1 and the spatial organization of insulin granule fusion in pancreatic β cells

Deng, K., Sun, K., Webster, H., Yau, B., Loudovaris, T., Thomas, H. E., Kebede, M. A., & Thorn, P. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.111036

Synaptic active zones are ordered nanostructures designed by supramolecular block copolymersPreprint

Sakamoto, H., & Shimobayashi, S. F. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.15.691964

The Role of Presynaptic Cytomatrix Protein Bassoon (BSN) in Tau Pathology and Propagation

Oo, W. J., Sia, W. T., Lee, J. Y., Chen, C. H., Chang, W., & Chye, S. M. (2026) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/0118715273400895251129055504

Ultrastructural and molecular analysis of cortico-striatal dopamine hub synapses

Lapios, P. (2024) · theses.fr (ABES) · doi:10.70675/527646a6zd9b5z4935z80ebz0950bba9d08e

Assembling the presynaptic active zone

Owald, D., & Sigrist, S. J. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.03.003 · Cited by 97 · see citing works

Molecular Mechanisms for Active Zone Assembly at Vertebrate Synapses

Huaiying, W. (2019) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

The Presynaptic Active Zone

Südhof, T. C. (2012) · Neuron · doi:10.1016/j.neuron.2012.06.012 · Cited by 1,062 · see citing works

Intracellular protein complexes involved in synapse assembly in presynaptic neurons

Han, K. A., Um, J. W., & Ko, J. (2018) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2018.11.008 · Cited by 19 · see citing works

Macromolecular complexes at active zones: integrated nano-machineries for neurotransmitter release

Chua, J. J. E. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1657-5 · Cited by 9 · see citing works