RIM genes differentially contribute to organizing presynaptic release sites

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RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction

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RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone

Schoch, S., Castillo, P. E., Jo, T., Mukherjee, K., Geppert, M., Wang, Y., Schmitz, F., Malenka, R. C., & Südhof, T. C. (2002) · Nature · doi:10.1038/415321a · Cited by 579 · see citing works

Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming

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RIM1α is required for presynaptic long-term potentiation

Castillo, P. E., Schoch, S., Schmitz, F., Südhof, T. C., & Malenka, R. C. (2002) · Nature · doi:10.1038/415327a · Cited by 389 · see citing works

RIM determines Ca2+ channel density and vesicle docking at the presynaptic active zone

Han, Y., Kaeser, P. S., Südhof, T. C., & Schneggenburger, R. (2011) · Neuron · doi:10.1016/j.neuron.2010.12.014 · Cited by 354 · see citing works

A post-docking role for active zone protein Rim

Koushika, S. P., Richmond, J. E., Hadwiger, G., Weimer, R. M., Jørgensen, E. M., & Nonet, M. L. (2001) · Nature Neuroscience · doi:10.1038/nn732 · Cited by 320 · see citing works

RIM Binding Proteins (RBPs) Couple Rab3-Interacting Molecules (RIMs) to Voltage-Gated Ca2+ Channels

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RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release

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Conformational switch of syntaxin-1 controls synaptic vesicle fusion

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Liprins, a Family of LAR Transmembrane Protein-tyrosine Phosphatase-interacting Proteins

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A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?

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RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13

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RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels

Kiyonaka, S., Wakamori, M., Miki, T., Uriu, Y., Nonaka, M., Bito, H., Beedle, A., Mori, E., Hara, Y., Waard, M. D., et al. (2007) · Nature Neuroscience · doi:10.1038/nn1904 · Cited by 262 · see citing works

Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1α

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A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones

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The RIM/NIM Family of Neuronal C2 Domain Proteins

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Autonomous Function of Synaptotagmin 1 in Triggering Synchronous Release Independent of Asynchronous Release

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Synaptotagmin-2 Is Essential for Survival and Contributes to Ca 2+ Triggering of Neurotransmitter Release in Central and Neuromuscular Synapses

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SCRAPPER-Dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release

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Distinct Rab Binding Specificity of Rim1, Rim2, Rabphilin, and Noc2

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UNC-13 and UNC-10/Rim Localize Synaptic Vesicles to Specific Membrane Domains

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Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation

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Molecular organization and plasticity of the cytomatrix at the active zone

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Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch

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Redundant functions of RIM1α and RIM2α in Ca2+‐triggered neurotransmitter release

Schoch, S., Mittelstaedt, T., Kaeser, P. S., Padgett, D., Feldmann, N., Chevaleyre, V., Castillo, P. E., Hammer, R. E., Han, W., Schmitz, F., et al. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601425 · Cited by 126 · see citing works

Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins☆☆Sequence data from this article have been deposited with the GenBank Data Library under Accession Nos. AF548738 and AF548739.

Wang, Y., & Südhof, T. C. (2003) · Genomics · doi:10.1016/s0888-7543(02)00024-1 · Cited by 112 · see citing works

cAMP/PKA signaling and RIM1α mediate presynaptic LTP in the lateral amygdala

Fourcaudot, E., Gambino, F., Humeau, Y., Casassus, G., Shaban, H., Poulain, B., & Lüthi, A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806938105 · Cited by 105 · see citing works

ELKS2α/CAST deletion selectively increases neurotransmitter release at inhibitory synapses

Kaeser, P. S., Deng, L., Chávez, A. E., Liu, X., Castillo, P. E., & Südhof, T. C. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.019 · Cited by 102 · see citing works

Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family

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RIM1α and RIM1β are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functions

Kaeser, P. S., Kwon, H.-B., Chiu, C.-Y. Q., Deng, L., Castillo, P., & Südhof, T. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3235-08.2008 · Cited by 97 · see citing works

RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning

Kaeser, P. S., Kwon, H.-B., Blundell, J., Chevaleyre, V., Morishita, W., Malenka, R. C., Powell, C. M., Castillo, P. E., & Südhof, T. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806679105 · Cited by 74 · see citing works

Adapter protein 14-3-3 is required for a presynaptic form of LTP in the cerebellum

Simsek‐Duran, F., Linden, D. J., & Lónárt, G. (2004) · Nature Neuroscience · doi:10.1038/nn1348 · Cited by 53 · see citing works

Rab3-interacting Molecule γ Isoforms Lacking the Rab3-binding Domain Induce Long Lasting Currents but Block Neurotransmitter Vesicle Anchoring in Voltage-dependent P/Q-type Ca2+ Channels

Uriu, Y., Kiyonaka, S., Miki, T., Yagi, M., Akiyama, S., Mori, E., Nakao, A., Beedle, A. M., Campbell, K. P., Wakamori, M., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.101311 · Cited by 46 · see citing works

Mutation Associated with an Autosomal Dominant Cone-Rod Dystrophy CORD7 Modifies RIM1-Mediated Modulation of Voltage-Dependent Ca2+ Channels

Miki, T., Kiyonaka, S., Uriu, Y., Waard, M. D., Wakamori, M., Beedle, A., Campbell, K., & Mori, Y. (2007) · Channels · doi:10.4161/chan.4660 · Cited by 34 · see citing works

Pushing synaptic vesicles over the RIM

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DIRECT INTERACTIONS BETWEEN C. ELEGANS RAB-3 AND RIM PROVIDE A MECHANISM TO TARGET VESICLES TO THE PRESYNAPTIC DENSITY

Gracheva, E. O., Hadwiger, G., Nonet, M., & Richmond, J. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.08.026 · Cited by 1 · see citing works

The landscape of genomic alterations across childhood cancers

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Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

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The Presynaptic Active Zone

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Molecular Mechanisms for Synchronous, Asynchronous, and Spontaneous Neurotransmitter Release

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CircRNA accumulation in the aging mouse brain

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Synaptic vesicle recycling: steps and principles

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Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling

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Presynaptic calcium channels: specialized control of synaptic neurotransmitter release

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Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease

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Sensory Processing at Ribbon Synapses in the Retina and the Cochlea

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Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone

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The molecular machinery of neurotransmitter release (Nobel lecture).

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De Novo Insertions and Deletions of Predominantly Paternal Origin Are Associated with Autism Spectrum Disorder

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Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism

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Unusual Processing Generates SPA LncRNAs that Sequester Multiple RNA Binding Proteins

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Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

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Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats

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Nanoscale Subsynaptic Domains Underlie the Organization of the Inhibitory Synapse

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Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment

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E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

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The Active Zone Protein Family ELKS Supports Ca2+Influx at Nerve Terminals of Inhibitory Hippocampal Neurons

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Molecular Machines Regulating the Release Probability of Synaptic Vesicles at the Active Zone

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Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders

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Circular RNAs: A Novel Player in Development and Disease of the Central Nervous System

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RIM1α SUMOylation Is Required for Fast Synaptic Vesicle Exocytosis

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RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes

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ELKS active zone proteins as multitasking scaffolds for secretion

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Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus

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Targeted, High-Resolution RNA Sequencing of Non-coding Genomic Regions Associated With Neuropsychiatric Functions

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Adipose tissue coregulates cognitive function

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RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse

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ELKS/Voltage-Dependent Ca2+ Channel-β Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic β Cells

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Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses

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Honeybee gut microbiota modulates host behaviors and neurological processesPreprint

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Visualizing Presynaptic Calcium Dynamics and Vesicle Fusion with a Single Genetically Encoded Reporter at Individual Synapses

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Identification of Novel Targets of RBM5 in the Healthy and Injured Brain

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MicroRNA Alteration in Developing Rat Oligodendrocyte Precursor Cells Induced by Hypoxia-Ischemia

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Episodic and Electrical Nervous System Disorders Caused by Nonchannel Genes

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The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release

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Genome-wide association study of antibody responses to Plasmodium falciparum candidate vaccine antigens

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New insights into tardive dyskinesia genetics: Implementation of whole-exome sequencing approach

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Aberrant methylation in neurofunctional gene serves as a hallmark of tumorigenesis and progression in colorectal cancer

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Early Metazoan Origin and Multiple Losses of a Novel Clade of RIM Presynaptic Calcium Channel Scaffolding Protein Homologs

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Cortical development dynamics across autism spectrum disorder mouse models

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How Do RIM-BPs Link Voltage-Gated Ca 2+ Channels to Evoked Neurotransmitter Release?

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Differential Requirement for Protein Synthesis in Presynaptic Unmuting and Muting in Hippocampal Glutamate Terminals

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Nanoscaled RIM clustering at presynaptic active zones revealed by endogenous tagging

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Spinal cord injury regulates circular RNA expression in axons

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Social isolation-induced transcriptomic changes in mouse hippocampus impact the synapse and show convergence with human genetic risk for neurodevelopmental phenotypes

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RNA Binding Motif 5 Gene Deletion Modulates Cell Signaling in a Sex-Dependent Manner but Not Hippocampal Cell Death

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Der molekulare Mechanismus der Neurotransmitterfreisetzung und Nervenzell-Synapsen (Nobel-Aufsatz)†

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Molecular and Morphological Correlates of Synaptic Vesicle Priming

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Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids

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La machinerie moléculaire de sécrétion des neurotransmetteurs

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RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse

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RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction

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RIM Determines Ca²+ Channel Density and Vesicle Docking at the Presynaptic Active Zone

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Synaptic and non-synaptic roles of neural activity in sensory map development.

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