Weale, Michael E.

Common genetic variants influence human subcortical brain structures

Initiative, T. A. D. N., Hibar, D. P., The CHARGE Consortium, EPIGEN, IMAGEN, SYS, Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., et al. (2015) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 858

Natural selection on EPAS1 ( HIF2α ) associated with low hemoglobin concentration in Tibetan highlanders

Beall, C. M., Cavalleri, G. L., Deng, L., Elston, R. C., Gao, Y., Knight, J., Li, C., Li, J. C., Liang, Y., McCormack, M., et al. (2010) · Proceedings of the National Academy of Sciences

High Altitude and HypoxiaGenetics and Physical Performance

Cited by 845

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

the Alzheimer’s Disease Neuroimaging Initiative, E. C., Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., et al. (2014) · Brain Imaging and Behavior

Genetic Associations and EpidemiologyFunctional Brain Connectivity Studies

Cited by 838

The transcriptional landscape of age in human peripheral blood

Peters, M. J., Joehanes, R., Pilling, L. C., Schurmann, C., Conneely, K. N., Powell, J., Reinmaa, E., Sutphin, G. L., Zhernakova, A., Schramm, K., et al. (2015) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation

Cited by 725

Genetic variability in the regulation of gene expression in ten regions of the human brain

UK Brain Expression Consortium, Ramasamy, A., North American Brain Expression Consortium, Trabzuni, D., Guelfi, S., Varghese, V., Smith, C., Walker, R., De, T., Coin, L., et al. (2014) · Nature Neuroscience

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 644

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

Cruchaga, C., Karch, C. M., Jin, S. C., Benitez, B. A., Cai, Y., Guerreiro, R., Harari, O., Norton, J., Budde, J., Bertelsen, S., et al. (2014) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 461

Long-Range LD Can Confound Genome Scans in Admixed Populations

Price, A. L., Weale, M. E., Patterson, N., Myers, S. R., Need, A. C., Shianna, K. V., Ge, D., Rotter, J. I., Torres, E., Taylor, K. D., et al. (2008) · The American Journal of Human Genetics

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 443

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyMemory and Neural Mechanisms

Cited by 299

An additional k-means clustering step improves the biological features of WGCNA gene co-expression networks

The United Kingdom Brain Expression Consortium, Botía, J. A., Vandrovcova, J., Forabosco, P., Guelfi, S., D’Sa, K., Hardy, J., Lewis, C. M., Ryten, M., & Weale, M. E. (2017) · BMC Systems Biology

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 289

UK Biobank release and systematic evaluation of optimised polygenic risk scores for 53 diseases and quantitative traits

Thompson, D. J., Wells, D., Selzam, S., Peneva, I., Moore, R., Sharp, K., Tarran, W. A., Beard, E. J., Riveros-Mckay, F., Giner-Delgado, C., et al. (2022) · medRxiv

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 280

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

Trabzuni, D., Wray, S., Vandrovcova, J., Ramasamy, A., Walker, R., Smith, C., Luk, C., Gibbs, J. R., Dillman, A., Hernandez, D. G., et al. (2012) · Human Molecular Genetics

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 252

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

Trabzuni, D., Ryten, M., Walker, R., Smith, C., Imran, S., Ramasamy, A., Weale, M. E., & Hardy, J. (2011) · Journal of Neurochemistry

Molecular Biology Techniques and ApplicationsGene expression and cancer classification

Cited by 229

Insights into TREM2 biology by network analysis of human brain gene expression data

Forabosco, P., Ramasamy, A., Trabzuni, D., Walker, R., Smith, C., Bras, J., Levine, A. P., Hardy, J., Pocock, J. M., Guerreiro, R., et al. (2013) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 180

Genomics implicates adaptive and innate immunity in Alzheimer’s and Parkinson’s diseases

Gagliano, S. A., Pouget, J. G., Hardy, J., Knight, J., Barnes, M. R., Ryten, M., & Weale, M. E. (2016) · Annals of Clinical and Translational Neurology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 85

Evolution of a Length Polymorphism in the Human PER3 Gene, a Component of the Circadian System

Nadkarni, N. A., Weale, M. E., von Schantz, M., & Thomas, M. G. (2005) · Journal of Biological Rhythms

Circadian rhythm and melatoninGenetic diversity and population structure

Cited by 76

Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci

Holton, P., Ryten, M., Nalls, M., Trabzuni, D., Weale, M. E., Hernandez, D., Crehan, H., Gibbs, J. R., Mayeux, R., Haines, J. L., et al. (2013) · Annals of Human Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 48

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

Trabzuni, D., Ryten, M., Walker, R., Smith, C., Imran, S., Ramasamy, A., Weale, M., & Hardy, J. (2012) · Journal of Neurochemistry

Molecular Biology Techniques and ApplicationsGene expression and cancer classification

Cited by 13