Cooney, Gregory J.

Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle

Yu, C., Chen, Y., Cline, G. W., Zhang, D., Zong, H., Wang, Y., Bergeron, R., Kim, J. K., Cushman, S. W., Cooney, G. J., et al. (2002) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerLipid metabolism and biosynthesis

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The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

Solon-Biet, S. M., McMahon, A. C., Ballard, J. W. O., Ruohonen, K., Wu, L. E., Cogger, V. C., Warren, A., Huang, X., Pichaud, N., Melvin, R. G., et al. (2014) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

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Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I

Turner, N., Li, J.-Y., Gosby, A., To, S. W. C., Cheng, Z., Miyoshi, H., Taketo, M. M., Cooney, G. J., Kraegen, E. W., James, D. E., et al. (2008) · Diabetes

Berberine and alkaloids researchMetabolism, Diabetes, and Cancer

Cited by 535

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle

Turner, N., Bruce, C. R., Beale, S. M., Hoehn, K. L., So, T., Rolph, M. S., & Cooney, G. J. (2007) · Diabetes

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 520

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

Turner, N., Kowalski, G. M., Leslie, S. J., Risis, S., Yang, C., Lee-Young, R. S., Babb, J. R., Meikle, P. J., Lancaster, G. I., Henstridge, D. C., et al. (2013) · Diabetologia

Diet, Metabolism, and DiseaseAdipokines, Inflammation, and Metabolic Diseases

Cited by 430

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet–induced insulin resistance

Bruce, C. R., Hoy, A. J., Turner, N., Watt, M. J., Allen, T. L., Carpenter, K., Cooney, G. J., Febbraio, M. A., & Kraegen, E. W. (2009) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

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AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats

Iglesias, M. A., Ye, J.-M., Frangioudakis, G., Saha, A. K., Tomas, E., Ruderman, N. B., Cooney, G. J., & Kraegen, E. W. (2002) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

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Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle

Ellis, B. A., Poynten, A., Lowy, A. J., Furler, S. M., Chisholm, D. J., Kraegen, E. W., & Cooney, G. J. (2000) · American Journal of Physiology-Endocrinology and Metabolism

Lipid metabolism and biosynthesisAdipose Tissue and Metabolism

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Muscle Oxidative Capacity Is a Better Predictor of Insulin Sensitivity than Lipid Status

Bruce, C. R., Anderson, M. J., Carey, A. L., Newman, D. G., Bonen, A., Kriketos, A. D., Cooney, G. J., & Hawley, J. A. (2003) · The Journal of Clinical Endocrinology & Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 234

Dietary protein, aging and nutritional geometry

Simpson, S. J., Le Couteur, D. G., Raubenheimer, D., Solon-Biet, S. M., Cooney, G. J., Cogger, V. C., & Fontana, L. (2017) · Ageing Research Reviews

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

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Increased Efficiency of Fatty Acid Uptake Contributes to Lipid Accumulation in Skeletal Muscle of High Fat-Fed Insulin-Resistant Rats

Hegarty, B. D., Cooney, G. J., Kraegen, E. W., & Furler, S. M. (2002) · Diabetes

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

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Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity

Hoehn, K. L., Turner, N., Swarbrick, M. M., Wilks, D., Preston, E., Phua, Y., Joshi, H., Furler, S. M., Larance, M., Hegarty, B. D., et al. (2010) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

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Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

Alexopoulos, S. J., Chen, S.-Y., Brandon, A. E., Salamoun, J. M., Byrne, F. L., Garcia, C. J., Beretta, M., Olzomer, E. M., Shah, D. P., Philp, A. M., et al. (2020) · Nature Communications

Adipose Tissue and MetabolismPharmacology and Obesity Treatment

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Mice with a Disruption of the Imprinted Grb10 Gene Exhibit Altered Body Composition, Glucose Homeostasis, and Insulin Signaling during Postnatal Life

Smith, F. M., Holt, L. J., Garfield, A. S., Charalambous, M., Koumanov, F., Perry, M., Bazzani, R., Sheardown, S. A., Hegarty, B. D., Lyons, R. J., et al. (2007) · Molecular and Cellular Biology

Genetic Syndromes and ImprintingMetabolism, Diabetes, and Cancer

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Triglycerides, fatty acids and insulin resistance - hyperinsulinemia

Kraegen, E., Cooney, G., Ye, J., & Thompson, A. (2001) · Experimental and Clinical Endocrinology & Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsMetabolism, Diabetes, and Cancer

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Effects of individual fatty acids on glucose uptake and glycogen synthesis in soleus muscle in vitro

Thompson, A. L., Lim-Fraser, M. Y.-C., Kraegen, E. W., & Cooney, G. J. (2000) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerLipid metabolism and biosynthesis

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Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation

Hoy, A. J., Brandon, A. E., Turner, N., Watt, M. J., Bruce, C. R., Cooney, G. J., & Kraegen, E. W. (2009) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

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Treatment of type 2 diabetes with the designer cytokine IC7Fc

Findeisen, M., Allen, T. L., Henstridge, D. C., Kammoun, H., Brandon, A. E., Baggio, L. L., Watt, K. I., Pal, M., Cron, L., Estevez, E., et al. (2019) · Nature

Cytokine Signaling Pathways and InteractionsAdipokines, Inflammation, and Metabolic Diseases

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Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats

Reznick, J., Preston, E., Wilks, D. L., Beale, S. M., Turner, N., & Cooney, G. J. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Circadian rhythm and melatoninDietary Effects on Health

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Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification

Bruce, C. R., Brolin, C., Turner, N., Cleasby, M. E., van der Leij, F. R., Cooney, G. J., & Kraegen, E. W. (2007) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

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Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed?

Small, L., Brandon, A. E., Turner, N., & Cooney, G. J. (2018) · American Journal of Physiology-Endocrinology and Metabolism

Diet, Metabolism, and DiseaseAdipokines, Inflammation, and Metabolic Diseases

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Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunction

Kraegen, E. W., Cooney, G. J., & Turner, N. (2008) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

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Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress

Wright, L. E., Brandon, A. E., Hoy, A. J., Forsberg, G.-B., Lelliott, C. J., Reznick, J., Löfgren, L., Oscarsson, J., Strömstedt, M., Cooney, G. J., et al. (2011) · Diabetologia

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

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Nitrosative modifications of protein and lipid signaling molecules by reactive nitrogen species

White, P. J., Charbonneau, A., Cooney, G. J., & Marette, A. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

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