Mice with a Disruption of the Imprinted Grb10 Gene Exhibit Altered Body Composition, Glucose Homeostasis, and Insulin Signaling during Postnatal Life

Leptin and the regulation of body weight in mammals

Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405 · see citing works

Insulin signalling and the regulation of glucose and lipid metabolism

Saltiel, A. R., & Kahn, C. R. (2001) · Nature · doi:10.1038/414799a · Cited by 5,326 · see citing works

Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

Brüning, J. C., Gautam, D., Burks, D. J., Gillette, J., Schubert, M., Orban, P. C., Klein, R., Krone, W., Müller-Wieland, D., & Kahn, C. R. (2000) · Science · doi:10.1126/science.289.5487.2122 · Cited by 2,235 · see citing works

Increased Insulin Sensitivity and Obesity Resistance in Mice Lacking the Protein Tyrosine Phosphatase-1B Gene

Elchebly, M., Payette, P., Michaliszyn, E., Cromlish, W., Collins, S., Loy, A. L., Normandin, D., Cheng, A., Himms-Hagen, J., Chan, C.-C., et al. (1999) · Science · doi:10.1126/science.283.5407.1544 · Cited by 2,210 · see citing works

Transposable elements: targets for early nutritional effects on epigenetic gene regulation

Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5293-5300.2003 · Cited by 2,019 · cited 1× · see citing works

Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Klaman, L. D., Boss, O., Peroni, O. D., Kim, J. K., Martino, J. L., Zabolotny, J. M., Moghal, N., Lubkin, M., Kim, Y.-B., Sharpe, A. H., et al. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.15.5479-5489.2000 · Cited by 1,235 · see citing works

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

Musarò, A., McCullagh, K., Paul, A., Houghton, L., Dobrowolny, G., Molinaro, M., Barton, E. R., L Sweeney, H., & Rosenthal, N. (2001) · Nature Genetics · doi:10.1038/84839 · Cited by 1,137 · see citing works

Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

Blüher, M., Michael, M. D., Peroni, O. D., Ueki, K., Carter, N., Kahn, B. B., & Kahn, C. R. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00199-5 · Cited by 806 · see citing works

Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases

Waterland, R. A., & Jirtle, R. L. (2003) · Nutrition · doi:10.1016/j.nut.2003.09.011 · Cited by 783 · see citing works

Neuronal PTP1B regulates body weight, adiposity and leptin action

Bence, K. K., Delibegovic, M., Xue, B., Gorgun, C. Z., Hotamisligil, G. S., Neel, B. G., & Kahn, B. B. (2006) · Nature Medicine · doi:10.1038/nm1435 · Cited by 633 · see citing works

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

Accili, D., Drago, J., Lee, E. J., Johnson, M. D., Cool, M. H., Salvatore, P., Asico, L. D., José, P. A., Taylor, S. I., & Westphal, H. (1996) · Nature Genetics · doi:10.1038/ng0196-106 · Cited by 594 · see citing works

Suppression of body fat accumulation in myostatin-deficient mice

McPherron, A. C., & Lee, S.-J. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0213562 · Cited by 505 · see citing works

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

Stiles, B., Wang, Y., Stahl, A., Bassilian, S., Lee, W. P., Kim, Y.-J., Sherwin, R., Devaskar, S., Lesche, R., Magnuson, M. A., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308617100 · Cited by 436 · see citing works

Myostatin Knockout in Mice Increases Myogenesis and Decreases Adipogenesis

Lin, J., Arnold, H. B., Della-Fera, M. A., Azain, M. J., Hartzell, D. L., & Baile, C. A. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6500 · Cited by 313 · see citing works

Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality.

Joshi, R. L., Lamothe, B., Cordonnier, N., Mesbah, K., Monthioux, E., Jami, J., & Bucchini, D. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00498.x · Cited by 281 · see citing works

Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

Charalambous, M., Smith, F. M., Bennett, W. R., Crew, T. E., Mackenzie, F. E., & Ward, A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1532175100 · Cited by 279 · see citing works

Insulin Receptor Knockout Mice

Kitamura, T., Kahn, C. R., & Accili, D. (2003) · Annual Review of Physiology · doi:10.1146/annurev.physiol.65.092101.142540 · Cited by 259 · see citing works

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

Sleeman, M. W., Wortley, K. E., Lai, K. V., Gowen, L. C., Kintner, J., Kline, W. O., García, K., Stitt, T. N., Yancopoulos, G. D., Wiegand, S. J., et al. (2005) · Nature Medicine · doi:10.1038/nm1178 · Cited by 255 · see citing works

The Grb10/Nedd4 Complex Regulates Ligand-Induced Ubiquitination and Stability of the Insulin-Like Growth Factor I Receptor

Vecchione, A. M., Marchese, A., Henry, P., Rotin, D., & Morrione, A. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.9.3363-3372.2003 · Cited by 251 · see citing works

Specific Inhibition of PTEN Expression Reverses Hyperglycemia in Diabetic Mice

Butler, M., McKay, R. A., Popoff, I., Gaarde, W. A., Witchell, D. R., Murray, S. F., Dean, N. M., Bhanot, S., & Monia, B. P. (2002) · Diabetes · doi:10.2337/diabetes.51.4.1028 · Cited by 216 · see citing works

Inhibition of Clathrin-Mediated Endocytosis Selectively Attenuates Specific Insulin Receptor Signal Transduction Pathways

Ceresa, B. P., Kao, A. W., Santeler, S. R., & Pessin, J. E. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.7.3862 · Cited by 214 · see citing works

Regulation of growth and metabolism by imprinted genes

Smith, F. M., Garfield, A. S., & Ward, A. (2006) · Cytogenetic and Genome Research · doi:10.1159/000090843 · Cited by 196 · see citing works

Protein tyrosine phosphatases: the quest for negative regulators of insulin action

Asante‐Appiah, E., & Kennedy, B. P. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00462.2002 · Cited by 192 · see citing works

Molecular basis of insulin action

Combettes-Souverain, M., & Issad, T. (1986) · International Journal of Biochemistry · doi:10.1016/0020-711x(86)90171-0 · Cited by 191 · see citing works

Insulin Hypersensitivity and Resistance to Streptozotocin-Induced Diabetes in Mice Lacking PTEN in Adipose Tissue

Kurlawalla-Martinez, C., Stiles, B. L., Wang, Y., Devaskar, S. U., Kahn, B. B., & Wu, H. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2498-2510.2005 · Cited by 189 · see citing works

Grb10 and Grb14: enigmatic regulators of insulin action – and more?

Holt, L. J., & Siddle, K. (2005) · Biochemical Journal · doi:10.1042/bj20050216 · Cited by 175 · see citing works

The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions

Han, D. C., Shen, T., & Guan, J. (2001) · Oncogene · doi:10.1038/sj.onc.1204775 · Cited by 171 · see citing works

Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function.

Liu, F., & Roth, R. A. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.22.10287 · Cited by 171 · see citing works

Identification of the Meg1 / Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver–Russell syndrome gene

Miyoshi, N., Kuroiwa, Y., Kohda, T., Shitara, H., Yonekawa, H., Kawabe, T., Hasegawa, H., Barton, S. C., Surani, M. A., Kaneko‐Ishino, T., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1102 · Cited by 156 · see citing works

Fetal growth and adult diseases

Ozanne, S. E., Fernandez‐Twinn, D. S., & Hales, C. N. (2004) · Seminars in Perinatology · doi:10.1053/j.semperi.2003.10.015 · Cited by 152 · see citing works

Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark

Arnaúd, P. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg110 · Cited by 146 · see citing works

For Debate: Fetal and early postnatal growth restriction lead to diabetes, the metabolic syndrome and renal failure*

Ozanne, S. E., & Hales, C. N. (2003) · Diabetologia · doi:10.1007/s00125-003-1131-7 · Cited by 139 · see citing works

Improved glucose homeostasis and enhanced insulin signalling in Grb14‐deficient mice

Cooney, G. J., Lyons, R. J., Crew, A. J., Jensen, T. E., Molero, J. C., Mitchell, C. J., Biden, T. J., Ormandy, C. J., James, D. E., & Daly, R. J. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600082 · Cited by 136 · see citing works

Grb10 Interacts Differentially with the Insulin Receptor, Insulin-like Growth Factor I Receptor, and Epidermal Growth Factor Receptor via the Grb10 Src Homology 2 (SH2) Domain and a Second Novel Domain Located between the Pleckstrin Homology and SH2 Domains

He, W., Rose, D. W., Olefsky, J. M., & Gustafson, T. A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.12.6860 · Cited by 134 · see citing works

Are the metabolic effects of GH and IGF-I separable?

Mauras, N., & Haymond, M. W. (2005) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2004.12.003 · Cited by 131 · see citing works

The cloning of Grb10 reveals a new family of SH2 domain proteins.

Ooi, J., Yajnik, V., Immanuel, D., Gordon, M., Moskow, J. J., Buchberg, A. M., & Margolis, B. L. (1995) · PubMed · Cited by 128 · see citing works

Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites

Hikichi, T. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg232 · Cited by 120 · see citing works

Grb10 Inhibits Insulin-stimulated Insulin Receptor Substrate (IRS)-Phosphatidylinositol 3-Kinase/Akt Signaling Pathway by Disrupting the Association of IRS-1/IRS-2 with the Insulin Receptor

Wick, K. R., Werner, E. D., Langlais, P. R., Ramos, F. J., Dong, L., Shoelson, S. E., & Liu, F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m208518200 · Cited by 119 · see citing works

Structural Basis for Inhibition of the Insulin Receptor by the Adaptor Protein Grb14

Depetris, R. S., Hu, J., Gimpelevich, I., Holt, L. J., Daly, R. J., & Hubbard, S. R. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.09.001 · Cited by 112 · see citing works

Grb10, a Positive, Stimulatory Signaling Adapter in Platelet-Derived Growth Factor BB-, Insulin-Like Growth Factor I-, and Insulin-Mediated Mitogenesis

Wang, J., Heping, D., Yousaf, N., Moussaif, M., Deng, Y., Boufelliga, A., Swamy, O. R., Leone, M. E., & Riedel, H. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6217 · Cited by 102 · see citing works

Identification of the Rat Adapter Grb14 as an Inhibitor of Insulin Actions

Kasus‐Jacobi, A., Perdereau, D., Auzan, C., Clauser, É., OBBERGHEN, E. V., Mauvais‐Jarvis, F., Girard, J. R., & Burnol, A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.40.26026 · Cited by 101 · see citing works

Role for the Adaptor Protein Grb10 in the Activation of Akt

Jahn, T., Seipel, P., Urschel, S., Peschel, C., & Duyster, J. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.4.979-991.2002 · Cited by 99 · see citing works

The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts.

Laviola, L., Giorgino, F., Chow, J. C., Baquero, J. A. G., Hansen, H. F., Ooi, J., Zhu, J., Riedel, H., & Smith, R. J. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119246 · Cited by 98 · see citing works

Increased Insulin Sensitivity and Hypoinsulinemia in APS Knockout Mice

Minami, A., Iseki, M., Kishi, K., Wang, M., Ogura, M., Furukawa, N., Hayashi, S., Yamada, M., Obata, T., Takeshita, Y., et al. (2003) · Diabetes · doi:10.2337/diabetes.52.11.2657 · Cited by 90 · see citing works

The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors

Stein, E. G., Gustafson, T. A., & Hubbard, S. R. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02282-7 · Cited by 86 · see citing works

Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades

Shiura, H., Miyoshi, N., Konishi, A., Wakisaka‐Saito, N., Suzuki, R., Muguruma, K., Kohda, T., Wakana, S., Yokoyama, M., Ishino, F., et al. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.02.047 · Cited by 76 · see citing works

The Adapter Protein GRB10 Is an Endogenous Negative Regulator of Insulin-Like Growth Factor Signaling

Dufresne, A. M., & Smith, R. J. (2005) · Endocrinology · doi:10.1210/en.2005-0150 · Cited by 75 · see citing works

Insulin-Like Growth Factor I-Mediated Skeletal Muscle Hypertrophy is Characterized by Increased mTOR-p70S6K Signaling without Increased Akt Phosphorylation

Song, Y., Godard, M. P., Li, Y., Richmond, S. R., Rosenthal, N. A., & Delafontaine, P. (2005) · Journal of Investigative Medicine · doi:10.2310/6650.2005.00309 · Cited by 71 · see citing works

Grb10: more than a simple adaptor protein

Mei, A. L. (2004) · Frontiers in bioscience · doi:10.2741/1226 · Cited by 70 · see citing works

Increased adipose tissue expression of Grb14 in several models of insulin resistance

Cariou, B., Capitaine, N., Marcis, V. L., Véga, N., Béréziat, V., Kergoat, M., Laville, M., Girard, J. R., Vidal, H., & Burnol, A. (2004) · The FASEB Journal · doi:10.1096/fj.03-0824fje · Cited by 65 · see citing works

Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation

Ramos, F. J., Langlais, P. R., Hu, D., Dong, L., & Liu, F. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00609.2005 · Cited by 60 · see citing works

Impact of the Liver-Specific Expression of SHIP2 (SH2-Containing Inositol 5′-Phosphatase 2) on Insulin Signaling and Glucose Metabolism in Mice

Fukui, K., Wada, T., Kagawa, S., Nagira, K., Ikubo, M., Ishihara, H., Kobayashi, M., & Sasaoka, T. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1958 · Cited by 59 · see citing works

Growth Factor Receptor-binding Protein 10 (Grb10) as a Partner of Phosphatidylinositol 3-Kinase in Metabolic Insulin Action

Deng, Y., Bhattacharya, S., Swamy, O. R., Tandon, R., Wang, Y., Janda, R., & Riedel, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304599200 · Cited by 52 · see citing works

Interaction with Grb14 results in site‐specific regulation of tyrosine phosphorylation of the insulin receptor

Nouaille, S., Blanquart, C., Zilberfarb, V., Boute, N., Perdereau, D., Roix, J., Burnol, A., & Issad, T. (2006) · EMBO Reports · doi:10.1038/sj.embor.7400668 · Cited by 43 · see citing works

The Adapter Protein ZIP Binds Grb14 and Regulates Its Inhibitory Action on Insulin Signaling by Recruiting Protein Kinase Cζ

Cariou, B., Perdereau, D., Cailliau, K., Browaeys‐Poly, E., Béréziat, V., Vasseur-Cognet, M., Girard, J. R., & Burnol, A. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.20.6959-6970.2002 · Cited by 42 · see citing works

Structural-proliferative units and organ growth: effects of insulin-like growth factor 2 on the growth of colon and skin

Bennett, W. R., Crew, T. E., Slack, J. M. W., & Ward, A. (2003) · Development · doi:10.1242/dev.00333 · Cited by 36 · see citing works

Specific inhibition by hGRB10ζ of insulin-induced glycogen synthase activation: evidence for a novel signaling pathway

Mounier, C., Lavoie, L., Dumas, V., Mohammad-Ali, K., Wu, J., Nantel, A., Bergeron, J. J. M., Thomas, D. Y., & Posner, B. I. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00439-1 · Cited by 33 · see citing works

Increased IGFR activity and glucose transport in cultured skeletal muscle from insulin receptor null mice

Shefi-Friedman, L., Wertheimer, E., Shen, S., Bak, A., Accili, D., & Sampson, S. R. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.281.1.e16 · Cited by 33 · see citing works

Estrogen-induced osteogenesis in intact female mice lacking ERβ

McDougall, K. E., Perry, M. J., Gibson, R., Bright, J. M., Colley, S. M., Hodgin, J. B., Smithies, O., & Tobias, J. H. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00071.2002 · Cited by 26 · see citing works

Pre- and early postnatal nongenetic determinants of type 2 diabetes

Ozanne, S. E., & Hales, C. N. (2002) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399402005240 · Cited by 24 · see citing works

Rapid Induction of IGF-IR Signaling in Normal and Tumor Tissue Following Intravenous Injection of IGF-I in Mice

Lee, A. V., Taylor, S., Greenall, J., Mills, J. D., Tonge, D. W., Zhang, P., George, J., Fiorotto, M. L., & Hadsell, D. L. (2003) · Hormone and Metabolic Research · doi:10.1055/s-2004-814141 · Cited by 23 · see citing works

Identification of candidate growth-regulating genes that are overexpressed in late gestation fetal liver in the rat

Gruppuso, P. A., Boylan, J. M., & Vaslet, C. A. (2000) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(00)00244-x · Cited by 17 · see citing works

Evidence for a priming effect on maternal resource allocation: implications for interbrood competition

Charalambous, M., Ward, A., & Hurst, L. D. (2003) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rsbl.2003.0028 · Cited by 13 · see citing works

Insulin Receptor Signaling in Normal and Insulin-Resistant StatesPreprint

Boucher, J., Kleinridders, A., & Kahn, C. R. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a009191 · Cited by 1,473 · see citing works

The mTOR‐regulated phosphoproteome reveals a mechanism of mTORC1‐mediated inhibition of growth factor signaling

Hsu, P. P., Kang, S. A., Rameseder, J., Zhang, Y., Ottina, K. A., Lim, D., Peterson, T. R., Choi, Y., Gray, N. S., Yaffe, M. B., et al. (2011) · Science · doi:10.1126/science.1199498 · Cited by 1,084 · see citing works

Biochemical and cellular properties of insulin receptor signalling

Haeusler, R. A., McGraw, T. E., & Accili, D. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.89 · Cited by 739 · see citing works

Sex-Based Differences in Skeletal Muscle Kinetics and Fiber-Type Composition

Haizlip, K. M., Harrison, B. C., & Leinwand, L. A. (2015) · Physiology · doi:10.1152/physiol.00024.2014 · Cited by 521 · see citing works

Signalling by insulin and IGF receptors: supporting acts and new players

Siddle, K. (2011) · Journal of Molecular Endocrinology · doi:10.1530/jme-11-0022 · Cited by 456 · see citing works

The role of genomic imprinting in biology and disease: an expanding view

Peters, J. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3766 · Cited by 432 · see citing works

Protein Kinase B (PKB/Akt), a Key Mediator of the PI3K Signaling Pathway

Fayard, E., Xue, G., Parcellier, A., Bozulic, L., & Hemmings, B. A. (2010) · Current topics in microbiology and immunology · doi:10.1007/82_2010_58 · Cited by 247 · see citing works

The Importance of Imprinting in the Human Placenta

Frost, J. M., & Moore, G. E. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001015 · Cited by 247 · see citing works

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

Garfield, A. S., Cowley, M., Smith, F. M., Moorwood, K., Stewart-Cox, J. E., Gilroy, K. E., Baker, S. L., Xia, J., Dalley, J. W., Hurst, L. D., et al. (2011) · Nature · doi:10.1038/nature09651 · Cited by 242 · see citing works

Sex-Related Differences in Gene Expression in Human Skeletal Muscle

Welle, S., Tawil, R., & Thornton, C. A. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001385 · Cited by 224 · see citing works

Nedd4 Controls Animal Growth by Regulating IGF-1 Signaling

Cao, X., Lill, N. L., Boase, N. A., Shi, P. P., Croucher, D. R., Shan, H., Qu, J., Sweezer, E. M., Place, T. L., Kirby, P., et al. (2008) · Science Signaling · doi:10.1126/scisignal.1160940 · Cited by 201 · see citing works

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

Dalgaard, K., Landgraf, K., Heyne, S., Lempradl, A., Longinotto, J., Gossens, K., Ruf, M., Orthofer, M., Strogantsev, R., Selvaraj, M., et al. (2016) · Cell · doi:10.1016/j.cell.2015.12.025 · Cited by 190 · see citing works

The origin and evolution of genomic imprinting and viviparity in mammals

Renfree, M. B., Suzuki, S., & Kaneko‐Ishino, T. (2012) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0151 · Cited by 179 · see citing works

Epigenetics, brain evolution and behaviour

Keverne, E. B., & Curley, J. P. (2008) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2008.03.001 · Cited by 165 · see citing works

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance

Fazakerley, D. J., Chaudhuri, R., Yang, P., Maghzal, G. J., Thomas, K. C., Krycer, J. R., Humphrey, S. J., Parker, B. L., Fisher-Wellman, K. H., Meoli, C. C., et al. (2018) · eLife · doi:10.7554/elife.32111 · Cited by 160 · see citing works

The Insulin Receptor: Both a Prototypical and Atypical Receptor Tyrosine KinasePreprint

Hubbard, S. R. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008946 · Cited by 155 · see citing works

Molecular Basis of Signaling Specificity of Insulin and IGF Receptors: Neglected Corners and Recent Advances

Siddle, K. (2012) · Frontiers in Endocrinology · doi:10.3389/fendo.2012.00034 · Cited by 154 · see citing works

An Unbiased Assessment of the Role of Imprinted Genes in an Intergenerational Model of Developmental Programming

Radford, E. J., ISGANAITIS, E. M., Jiménez‐Chillarón, J. C., Schroeder, J., Molla, M. N., Andrews, S., Didier, N., Charalambous, M., McEwen, K. R., Marazzi, G., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002605 · Cited by 116 · see citing works

Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy

Tognon, C. E., & Sorensen, P. H. B. (2012) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2011.638626 · Cited by 107 · see citing works

Maternally-inherited Grb10 reduces placental size and efficiency

Charalambous, M., Cowley, M., Geoghegan, F., Smith, F. M., Radford, E. J., Marlow, B. P., Graham, C. F., Hurst, L. D., & Ward, A. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2009.10.011 · Cited by 101 · see citing works

Maternal vitamin D depletion alters DNA methylation at imprinted loci in multiple generations

Xue, J., Schoenrock, S. A., Valdar, W. S. J., Tarantino, L. M., & Ideraabdullah, F. (2016) · Clinical Epigenetics · doi:10.1186/s13148-016-0276-4 · Cited by 100 · see citing works

Testosterone modulates gene expression pathways regulating nutrient accumulation, glucose metabolism and protein turnover in mouse skeletal muscle

Haren, M. T., Siddiqui, A. M., Armbrecht, H. J., Kevorkian, R. T., Kim, M. J., Haas, M. J., Mazza, A. D., Kumar, V. B., Green, M., Banks, W. A., et al. (2010) · International Journal of Andrology · doi:10.1111/j.1365-2605.2010.01061.x · Cited by 99 · see citing works

A survey of tissue-specific genomic imprinting in mammals

Prickett, A. R., & Oakey, R. J. (2012) · Molecular Genetics and Genomics · doi:10.1007/s00438-012-0708-6 · Cited by 96 · see citing works

Genomic imprinting, growth and maternal–fetal interactions

Cassidy, F. C., & Charalambous, M. (2018) · Journal of Experimental Biology · doi:10.1242/jeb.164517 · Cited by 95 · see citing works

SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins

Morris, D. L., Cho, K. W., Zhou, Y., & Rui, L. (2009) · Diabetes · doi:10.2337/db08-1388 · Cited by 93 · see citing works

Phenotypic Outcomes of Imprinted Gene Models in Mice: Elucidation of Pre- and Postnatal Functions of Imprinted Genes

Cleaton, M. A. M., Edwards, C. A., & Ferguson‐Smith, A. C. (2014) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-091212-153441 · Cited by 86 · see citing works

Regulation of insulin and type 1 insulin‐like growth factor signaling and action by the G rb10/14 and SH 2 B 1/ B 2 adaptor proteins

Desbuquois, B., Carré, N., & Burnol, A. (2012) · FEBS Journal · doi:10.1111/febs.12080 · Cited by 77 · see citing works

The Ubiquitin Ligase Nedd4-1 Is Required for Heart Development and Is a Suppressor of Thrombospondin-1

Fouladkou, F., Chen, L., Jiang, C., Zhou, L., She, Y., Walls, J. R., Kawabe, H., Brose, N., Henkelman, R. M., Huang, A., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.082347 · Cited by 75 · see citing works

Effects of Cadmium Exposure on DNA Methylation at Imprinting Control Regions and Genome-Wide in Mothers and Newborn Children

Cowley, M., Skaar, D. A., Jima, D. D., Maguire, R. L., Hudson, K. M., Park, S. S., Sorrow, P., & Hoyo, C. (2018) · Environmental Health Perspectives · doi:10.1289/ehp2085 · Cited by 76 · see citing works

Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14

Depetris, R. S., Wu, J., & Hubbard, S. R. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1642 · Cited by 72 · see citing works

Developmental regulation of somatic imprints

John, R. M., & Lefebvre, L. (2011) · Differentiation · doi:10.1016/j.diff.2011.01.007 · Cited by 70 · see citing works

Tissue-specific regulation and function of Grb10 during growth and neuronal commitment

Plasschaert, R. N., & Bartolomei, M. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1411254111 · Cited by 67 · see citing works

Dual Ablation of Grb10 and Grb14 in Mice Reveals Their Combined Role in Regulation of Insulin Signaling and Glucose Homeostasis

Holt, L. J., Lyons, R. J., Ryan, A. S., Beale, S. M., Ward, A., Cooney, G. J., & Daly, R. J. (2009) · Molecular Endocrinology · doi:10.1210/me.2008-0386 · Cited by 63 · see citing works

Genomic imprinting and its effects on postnatal growth and adult metabolism

Millership, S. J., de Pette, M. V., & Withers, D. J. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03197-z · Cited by 60 · see citing works

DNA methylation at differentially methylated regions of imprinted genes is resistant to developmental programming by maternal nutrition

Ivanova, E., Chen, J., Segonds-Pichon, A., Ozanne, S. E., & Kelsey, G. (2012) · Epigenetics · doi:10.4161/epi.22141 · Cited by 58 · see citing works

Developmental Programming Mediated by Complementary Roles of Imprinted Grb10 in Mother and Pup

Cowley, M., Garfield, A. S., Madon-Simon, M., Charalambous, M., Clarkson, R. W. E., Smalley, M. J., Kendrick, H. D., Isles, A. R., Parry, A., Carney, S., et al. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001799 · Cited by 58 · see citing works

Genes Whose Gain or Loss-Of-Function Increases Skeletal Muscle Mass in Mice: A Systematic Literature Review

Verbrugge, S. A. J., Schönfelder, M., Becker, L., Yaghoob Nezhad, F., Hrabě de Angelis, M., & Wackerhage, H. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00553 · Cited by 56 · see citing works

Liver and insulin resistance: New wine in old bottle!!!

Patel, B. M., & Goyal, R. K. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172657 · Cited by 50 · see citing works

FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia

Kazi, J. U., & Rönnstrand, L. (2012) · Molecular Oncology · doi:10.1016/j.molonc.2012.11.003 · Cited by 49 · see citing works

Grb10 regulates the development of fiber number in skeletal muscle

Holt, L. J., Turner, N. A., Mokbel, N., Trefely, S., Kanzleiter, T., Kaplan, W. H., Ormandy, C. J., Daly, R. J., & Cooney, G. J. (2012) · The FASEB Journal · doi:10.1096/fj.11-199349 · Cited by 49 · see citing works

Inputs and outputs of insulin receptor

Du, Y., & Wei, T. (2014) · Protein & Cell · doi:10.1007/s13238-014-0030-7 · Cited by 47 · see citing works

Stimulation of both estrogen and androgen receptors maintains skeletal muscle mass in gonadectomized male mice but mainly via different pathways

Svensson, J., Movérare‐Skrtic, S., Windahl, S. H., Swanson, C., & Sjögren, K. (2010) · Journal of Molecular Endocrinology · doi:10.1677/jme-09-0165 · Cited by 47 · see citing works

Disruption of Growth Factor Receptor–Binding Protein 10 in the Pancreas Enhances β-Cell Proliferation and Protects Mice From Streptozotocin-Induced β-Cell Apoptosis

Zhang, J., Zhang, N., Liu, M., Li, X., Zhou, L., Huang, W., Xu, Z., Liu, J., Musi, N., DeFronzo, R. A., et al. (2012) · Diabetes · doi:10.2337/db12-0249 · Cited by 46 · see citing works

Somatic Cell Nuclear Transfer Followed by CRIPSR/Cas9 Microinjection Results in Highly Efficient Genome Editing in Cloned Pigs

Sheets, T. P., Park, C., Park, K., Powell, A. M., Donovan, D. M., & Telugu, B. P. V. L. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17122031 · Cited by 46 · see citing works

Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes

Dollet, L., Kuefner, M., Caria, E., Rizo‐Roca, D., Pendergrast, L. A., Abdelmoez, A. M., Karlsson, H., Bjrnholm, M., Dalbram, E., Treebak, J. T., et al. (2022) · Diabetes · doi:10.2337/db20-0814 · Cited by 46 · see citing works

The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism

Lamming, D. W., Soliman, M. A., Rahman, A. M. A., Birsoy, K., Pawling, J., Frigolet, M. E., Lu, H., Fantus, I. G., Pasculescu, A., Zheng, Y., et al. (2013) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 44 · see citing works

Insulin‐Like Growth Factor I Regulation and Its Actions in Skeletal Muscle

Vassilakos, G., & Barton, E. R. (2018) · Comprehensive physiology · doi:10.1002/cphy.c180010 · Cited by 47 · see citing works

Genomic Imprinting – Roles and Regulation in Development

Kelsey, G. (2007) · KARGER eBooks · doi:10.1159/000109637 · Cited by 40 · see citing works

Genomic imprinting effects in a compromised in utero environment: Implications for a healthy pregnancy

Lim, A. L., & Ferguson‐Smith, A. C. (2009) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2009.10.008 · Cited by 39 · see citing works

Amelioration of Diabetic Mouse Nephropathy by Catalpol Correlates with Down-Regulation of Grb10 Expression and Activation of Insulin-Like Growth Factor 1 / Insulin-Like Growth Factor 1 Receptor Signaling

Yang, S., Deng, H., Zhang, Q., Xie, J., Zeng, H., Jin, X., Ling, Z., Shan, Q., Liu, M., Ma, Y., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151857 · Cited by 38 · see citing works

Hypothalamic Grb10 enhances leptin signalling and promotes weight loss

Liu, H., He, Y., Bai, J., Zhang, C., Zhang, F., Yang, Y., Luo, H., Yu, M., Liu, H., Tu, L., et al. (2023) · Nature Metabolism · doi:10.1038/s42255-022-00701-x · Cited by 36 · see citing works

The transcription regulator ATF4 is a mediator of skeletal muscle aging

Miller, M. J., Marcotte, G. R., Basisty, N., Wehrfritz, C., Ryan, Z. C., Strub, M. D., McKeen, A. T., Stern, J. I., Nath, K. A., Rasmussen, B. B., et al. (2023) · GeroScience · doi:10.1007/s11357-023-00772-y · Cited by 37 · see citing works

Unraveling the Mystery of Insulin Resistance: From Principle Mechanistic Insights and Consequences to Therapeutic Interventions

Mir, R., Jeelani, M., Alharthi, M. H., Rizvi, S. F., Sohail, S. K., Wani, J. I., Sabah, Z. U., BinAfif, W. F., Nandi, P. S., Alshahrani, A. M., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26062770 · Cited by 40 · see citing works

The insulin signalling network

Burchfield, J. G., Díaz‐Vegas, A., & James, D. E. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01349-z · Cited by 34 · see citing works

Grb10 Deletion Enhances Muscle Cell Proliferation, Differentiation and GLUT4 Plasma Membrane Translocation

Mokbel, N., Hoffman, N. J., Girgis, C. M., Small, L., Turner, N. A., Daly, R. J., Cooney, G. J., & Holt, L. J. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24628 · Cited by 33 · see citing works

Structural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4

Huang, Q., & Szebenyi, D. M. E. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.143412 · Cited by 33 · see citing works

Antagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1genes

Madon-Simon, M., Cowley, M., Garfield, A. S., Moorwood, K., Bauer, S. R., & Ward, A. (2014) · BMC Biology · doi:10.1186/s12915-014-0099-8 · Cited by 31 · see citing works

Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice

Holt, L. J., Brandon, A. E., Small, L., Suryana, E., Preston, E., Wilks, D. L., Mokbel, N., Coles, C. A., White, J. D., Turner, N. A., et al. (2018) · Endocrinology · doi:10.1210/en.2017-00851 · Cited by 31 · see citing works

Impulsive Choice in Mice Lacking Paternal Expression of Grb10 Suggests Intragenomic Conflict in Behavior

Dent, C. L., Humby, T., Lewis, K. S., Ward, A., Fischer‐Colbrie, R., Wilkinson, L. S., Wilkins, J. F., & Isles, A. R. (2018) · Genetics · doi:10.1534/genetics.118.300898 · Cited by 31 · see citing works

Post-natal imprinting: evidence from marsupials

Stringer, J. M., Pask, A. J., Shaw, G., & Renfree, M. B. (2014) · Heredity · doi:10.1038/hdy.2014.10 · Cited by 28 · see citing works

Comparative Transcriptome Profiling of Skeletal Muscle from Black Muscovy Duck at Different Growth Stages Using RNA-seq

Hu, Z., Cao, J., Liu, G., Zhang, H., & Liu, X. (2020) · Genes · doi:10.3390/genes11101228 · Cited by 28 · see citing works

Genomic Organization and Control of the Grb7 Gene Family

Lucas-Fernandez, E., García‐Palmero, I., & Villalobo, A. (2008) · Current Genomics · doi:10.2174/138920208783884847 · Cited by 28 · see citing works

Is there a genomically imprinted social brain?

Curley, J. P. (2011) · BioEssays · doi:10.1002/bies.201100060 · Cited by 27 · see citing works

Paternal Allele Influences High Fat Diet-Induced Obesity

Morita, S., Horii, T., Kimura, M., Arai, Y., Kamei, Y., Ogawa, Y., & Hatada, I. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085477 · Cited by 26 · see citing works

Postnatal Changes in the Expression Pattern of the Imprinted Signalling Protein XLαs Underlie the Changing Phenotype of Deficient Mice

Krechowec, S. O., Burton, K. L., Newlaczyl, A. U., Nunn, N., Vlatković, N., & Plagge, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029753 · Cited by 26 · see citing works

The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer

Naudin, C., Chevalier, C., & Roche, S. (2016) · Oncotarget · doi:10.18632/oncotarget.6929 · Cited by 31 · see citing works

Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestrin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation

Suryawan, A., & Davis, T. A. (2018) · Journal of Nutrition · doi:10.1093/jn/nxy044 · Cited by 26 · see citing works

Structural Basis for the Interaction of the Adaptor Protein Grb14 with Activated Ras

Qamra, R., & Hubbard, S. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072473 · Cited by 26 · see citing works

Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration

Yan, X., Himburg, H. A., Pohl, K., Quarmyne, M., Tran, E., Zhang, Y., Fang, T., Kan, J., Chao, N. J., Zhao, L., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.10.025 · Cited by 25 · see citing works

Cannabis alters DNA methylation at maternally imprinted and autism candidate genes in spermatogenic cells

Schrott, R., Greeson, K. W., King, D. E., Crow, K. M. S., Easley, C. A., & Murphy, S. K. (2022) · Systems Biology in Reproductive Medicine · doi:10.1080/19396368.2022.2073292 · Cited by 24 · see citing works

Dual Effect of the Adapter Growth Factor Receptor-Bound Protein 14 (Grb14) on Insulin Action in Primary Hepatocytes

Carré, N., Caüzac, M., Girard, J. R., & Burnol, A. (2008) · Endocrinology · doi:10.1210/en.2007-1196 · Cited by 23 · see citing works

Osteocalcin‐dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance

Tangseefa, P., Martin, S. K., Fitter, S., Baldock, P. A. J., Proud, C. G., & Zannettino, A. C. W. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.26163 · Cited by 23 · see citing works

Mitogenic roles of Gab1 and Grb10 as direct cellular partners in the regulation of MAP kinase signaling

Deng, Y., Zhang, M., & Riedel, H. (2008) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21829 · Cited by 22 · see citing works

Hybrid Mice Reveal Parent-of-Origin and Cis- and Trans-Regulatory Effects in the Retina

Shen, S. Q., Turro, E., & Corbo, J. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109382 · Cited by 22 · see citing works

Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency

Rahib, L., Sriram, G., Harada, M., Liao, J. C., & Dipple, K. M. (2009) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2008.11.163 · Cited by 20 · see citing works

Role of Grb10 in mTORC1-dependent regulation of insulin signaling and action in human skeletal muscle cells

Edick, A. M., Auclair, O., & Burgos, S. A. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00025.2019 · Cited by 19 · see citing works

Imprinted Gene Expression and Function of the Dopa Decarboxylase Gene in the Developing Heart

Prickett, A. R., Montibus, B., Barkas, N., Amante, S. M., Franco, M. M., Cowley, M., Puszyk, W. M., Shannon, M. F., Irving, M. D., Madon-Simon, M., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.676543 · Cited by 16 · see citing works

Knockdown of PRAS40 inhibits insulin action via proteasome-mediated degradation of IRS1 in primary human skeletal muscle cells

Wiza, C., de Wiza, D. H., Nascimento, E. B. M., Lehr, S., Al‐Hasani, H., & Ouwens, D. M. (2013) · Diabetologia · doi:10.1007/s00125-013-2861-9 · Cited by 18 · see citing works

Effects of Skeletal Muscle Hypertrophy on Fat Mass and Glucose Homeostasis in Humans and Animals: A Narrative Review with Systematic Literature Search

Havers, T., Held, S., Schönfelder, M., Geisler, S., & Wackerhage, H. (2025) · Sports Medicine · doi:10.1007/s40279-025-02263-w · Cited by 19 · see citing works

An evolutionarily distinct ringed seal in the Ilulissat Icefjord

Rosing‐Asvid, A., Löytynoja, A., Momigliano, P., Hansen, R. G., Scharff‐Olsen, C. H., Valtonen, M., Kammonen, J., Dietz, R., Rigét, F. F., Ferguson, S. H., et al. (2023) · Molecular Ecology · doi:10.1111/mec.17163 · Cited by 17 · see citing works

Dynamic Expression of Imprinted Genes in the Developing and Postnatal Pituitary Gland

Scagliotti, V., Esse, R., Willis, T. L., Howard, M. C., Carrus, I., Lodge, E. J., Andoniadou, C. L., & Charalambous, M. (2021) · Genes · doi:10.3390/genes12040509 · Cited by 18 · see citing works

Grb10 is involved in BCR-ABL-positive leukemia in mice

Illert, A. L., Albers, C., Kreutmair, S., Leischner, H., Peschel, C., Miething, C., & Duyster, J. (2014) · Leukemia · doi:10.1038/leu.2014.283 · Cited by 17 · see citing works

Treadmill training attenuate STZ-induced cognitive dysfunction in type 2 diabetic rats via modulating Grb10/IGF-R signaling

Zhang, Y., Chen, D., Zhang, M., Bian, J., Qian, S., & Kou, X. (2022) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2022.01.007 · Cited by 15 · see citing works

Role of Distinct Fat Depots in Metabolic Regulation and Pathological Implications

Sahu, B., Tikoo, O., Pati, B., Senapati, U., & Bal, N. C. (2022) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/112_2022_73 · Cited by 15 · see citing works

Mice lacking paternal expression of imprinted Grb10 are risk‐takers

Dent, C. L., Rienecker, K. D. A., Ward, A., Wilkins, J. F., Humby, T., & Isles, A. R. (2020) · Genes Brain & Behavior · doi:10.1111/gbb.12679 · Cited by 14 · see citing works

Growth Factor Receptor‐Bound Protein 10‐Mediated Negative Regulation of the Insulin‐Like Growth Factor‐1 Receptor‐Activated Signalling Pathway Results in Cognitive Disorder in Diabetic Rats

Ma, L., Wei, Q., Deng, H., Zhang, Q., Li, G., Tang, N., Xie, J., & Chen, Y. (2013) · Journal of Neuroendocrinology · doi:10.1111/jne.12040 · Cited by 14 · see citing works

Maternal GRB10 microdeletion is a novel cause of cystic placenta: Spectrum of genomic changes in the etiology of enlarged cystic placenta

Surti, U., Yatsenko, S. A., Hu, J., Bellissimo, D. B., Parks, W. T., & Hoffner, L. (2017) · Placenta · doi:10.1016/j.placenta.2017.05.018 · Cited by 14 · see citing works

Adapter proteins regulate insulin resistance and lipid metabolism in obesity

Chen, Z. (2016) · 中国科学通报：英文版 · doi:10.1007/s11434-016-1058-2 · Cited by 13 · see citing works

Growth receptor binding protein 10 inhibits glucose‐stimulated insulin release from pancreatic β‐cells associated with suppression of the insulin/insulin‐like growth factor‐1 signalling pathway

Li, L., Li, X., Zhu, Y., Zhang, M., Yin, D., Lu, J., Liu, F., Wang, C., & Jia, W. (2013) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12160 · Cited by 13 · see citing works

Immunity to Growth Factor Receptor–Bound Protein 10, a Signal Transduction Molecule, Inhibits the Growth of Breast Cancer in Mice

O‐Sullivan, I., Chopra, A., Carr, J. R., Kim, T. S., & Cohen, E. P. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-5685 · Cited by 13 · see citing works

GRB10 Imprinting Is Eutherian Mammal Specific

Stringer, J. M., Suzuki, S., Pask, A. J., Shaw, G., & Renfree, M. B. (2012) · Molecular Biology and Evolution · doi:10.1093/molbev/mss173 · Cited by 12 · see citing works

Evaluation of vitrification protocol of mouse ovarian tissue by effect of DNA methyltransferase-1 and paternal imprinted growth factor receptor-binding protein 10 on signaling pathways

He, Z.-Y., Wang, H., Zhou, X., Liang, X., Yan, B., Wang, R., Ma, L., & Wang, Y. (2017) · Cryobiology · doi:10.1016/j.cryobiol.2017.11.008 · Cited by 11 · see citing works

Importance of Both Imprinted Genes and Functional Heterogeneity in Pancreatic Beta Cells: Is There a Link?

CHABOSSEAU, P. L., Rutter, G. A., & Millership, S. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031000 · Cited by 10 · see citing works

Genomic Imprinting of Grb10 : Coadaptation or Conflict?

Wilkins, J. F. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001800 · Cited by 10 · see citing works

Transcriptome Dynamics and Potential Roles of Sox6 in the Postnatal Heart

An, C.-I., Ichihashi, Y., Peng, J., Sinha, N. R., & Hagiwara, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166574 · Cited by 10 · see citing works

Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes

Moorwood, K., Smith, F. M., Garfield, A. S., & Ward, A. (2024) · BMC Biology · doi:10.1186/s12915-024-01926-w · Cited by 8 · see citing works

Influencing the Social Group

McNamara, G. I., & Isles, A. R. (2014) · Advances in genetics · doi:10.1016/b978-0-12-800222-3.00006-1 · Cited by 8 · see citing works

Footprints of recent selection and variability in breed composition in the Göttingen Minipig genome.

Garke, C., Ytournel, F., Sharifi, A. R., Pimentel, E. C. G., Ludwig, A., & Simianer, H. (2014) · Animal Genetics · doi:10.1111/age.12150 · Cited by 10 · see citing works

Maternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growth

Eaton, S. A., Hough, T., Fischer‐Colbrie, R., & Peters, J. (2013) · Mammalian Genome · doi:10.1007/s00335-013-9462-2 · Cited by 7 · see citing works

Imprinted Genes Impact Upon Beta Cell Function in the Current (and Potentially Next) Generation

Villanueva-Hayes, C., & Millership, S. J. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.660532 · Cited by 6 · see citing works

Peripheral Disruption of the Grb10 Gene Enhances Insulin Signaling and Sensitivity In Vivo

Wang, L., Balas, B., Christ-Roberts, C. Y., Kim, R. Y., Ramos, F. J., Kikani, C. K., Li, C., Deng, C., Reyna, S. M., Musi, N., et al. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00679-07 · Cited by 138 · see citing works

Grb10 and Grb14: enigmatic regulators of insulin action – and more?

Holt, L. J., & Siddle, K. (2005) · Biochemical Journal · doi:10.1042/bj20050216 · Cited by 175 · see citing works

Dual Ablation of Grb10 and Grb14 in Mice Reveals Their Combined Role in Regulation of Insulin Signaling and Glucose Homeostasis

Holt, L. J., Lyons, R. J., Ryan, A. S., Beale, S. M., Ward, A. B., Cooney, G. J., & Daly, R. J. (2009) · Endocrine Reviews · doi:10.1210/edrv.30.5.9991 · Cited by 5 · see citing works

Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes

Moorwood, K., Smith, F. M., Garfield, A. S., & Ward, A. (2024) · BMC Biology · doi:10.1186/s12915-024-01926-w · Cited by 8 · see citing works

Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis and insulin signalling during post-natal

Smith, F. M., Holt, L. J., Garfield, A. S., Charalambous, M., Koumanov, F., Perry, M., Bazzani, R., Sheardown, S. A., Hegarty, B. D., Lyons, R. J., et al. (2013)