Tschöp, Matthias H.

Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice

Liskiewicz, A., Khalil, A., Liskiewicz, D., Novikoff, A., Grandl, G., Maity-Kumar, G., Gutgesell, R. M., Bakhti, M., Bastidas-Ponce, A., Czarnecki, O., et al. (2023) · Nature Metabolism

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 110

Monomeric GLP-1/GIP/Glucagon Triagonism Corrects Obesity, Hepatosteatosis, and Dyslipidemia in Female Mice

Jall, S., Sachs, S., Clemmensen, C., Finan, B., Neff, F., DiMarchi, R. D., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2017) · Molecular Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 107

Gut hormone co-agonists for the treatment of obesity: from bench to bedside

Nogueiras, R., Nauck, M. A., & Tschöp, M. H. (2023) · Nature Metabolism

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 102

Peptide lipidation stabilizes structure to enhance biological function

Ward, B. P., Ottaway, N. L., Perez-Tilve, D., Ma, D., Gelfanov, V. M., Tschöp, M. H., & DiMarchi, R. D. (2013) · Molecular Metabolism

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 101

Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21

Kim, T., Nason, S., Holleman, C., Pepin, M., Wilson, L., Berryhill, T. F., Wende, A. R., Steele, C., Young, M. E., Barnes, S., et al. (2018) · Diabetes

Fibroblast Growth Factor ResearchDrug Transport and Resistance Mechanisms

Cited by 97

Gut hormone-based pharmacology: novel formulations and future possibilities for metabolic disease therapy

Tschöp, M., Nogueiras, R., & Ahrén, B. (2023) · Diabetologia

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 92

Dual melanocortin‐4 receptor and GLP‐1 receptor agonism amplifies metabolic benefits in diet‐induced obese mice

Clemmensen, C., Finan, B., Fischer, K., Tom, R. Z., Legutko, B., Sehrer, L., Heine, D., Grassl, N., Meyer, C. W., Henderson, B., et al. (2015) · EMBO Molecular Medicine

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 89

GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight

Vogel, H., Wolf, S., Rabasa, C., Rodriguez-Pacheco, F., Babaei, C. S., Stöber, F., Goldschmidt, J., DiMarchi, R. D., Finan, B., Tschöp, M. H., et al. (2016) · Neuropharmacology

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 86

Dual and Triple Incretin-Based Co-agonists: Novel Therapeutics for Obesity and Diabetes

Gutgesell, R. M., Nogueiras, R., Tschöp, M. H., & Müller, T. D. (2024) · Diabetes Therapy

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 61

Functional identity of hypothalamic melanocortin neurons depends on Tbx3

Quarta, C., Fisette, A., Xu, Y., Colldén, G., Legutko, B., Tseng, Y.-T., Reim, A., Wierer, M., De Rosa, M. C., Klaus, V., et al. (2019) · Nature Metabolism

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 54

Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates

Knerr, P. J., Mowery, S. A., Finan, B., Perez-Tilve, D., Tschöp, M. H., & DiMarchi, R. D. (2020) · Peptides

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 49

Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice

Isken, F., Weickert, M. O., Tschöp, M. H., Nogueiras, R., Möhlig, M., Abdelrahman, A., Klaus, S., Thorens, B., & Pfeiffer, A. F. (2009) · Diabetologia

Diet, Metabolism, and DiseaseRegulation of Appetite and Obesity

Cited by 36

Outstanding Scientific Achievement Award Lecture 2011: Defeating Diabesity

Tschöp, M. H., & DiMarchi, R. D. (2012) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 32

GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice

Décarie-Spain, L., Fisette, A., Zhu, Z., Yang, B., DiMarchi, R. D., Tschöp, M. H., Finan, B., Fulton, S., & Clemmensen, C. (2019) · Neuropharmacology

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 27

GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease

Sachs, S., Götz, A., Finan, B., Feuchtinger, A., DiMarchi, R. D., Döring, Y., Weber, C., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2023) · Cardiovascular Diabetology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 24

Dual gut hormone receptor agonists for diabetes and obesity

Bass, J., Tschöp, M. H., & Beutler, L. R. (2023) · Journal of Clinical Investigation

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 21

Nutropioids, hedonism in the gut?

Pfluger, P. T., Schriever, S. C., & Tschöp, M. H. (2012) · Cell Metabolism

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 7