Hubbard, Gene B.

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs

Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., Palmer, A. K., Ikeno, Y., Hubbard, G. B., Lenburg, M., et al. (2015) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 2,584

Senolytics improve physical function and increase lifespan in old age

Xu, M., Pirtskhalava, T., Farr, J. N., Weigand, B. M., Palmer, A. K., Weivoda, M. M., Inman, C. L., Ogrodnik, M. B., Hachfeld, C. M., Fraser, D. G., et al. (2018) · Nature Medicine

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 2,287

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

Laberge, R.-M., Sun, Y., Orjalo, A. V., Patil, C. K., Freund, A., Zhou, L., Curran, S. C., Davalos, A. R., Wilson-Edell, K. A., Liu, S., et al. (2015) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,160

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., González-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., et al. (2016) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 451

Reduced Expression of MYC Increases Longevity and Enhances Healthspan

Hofmann, J. W., Zhao, X., De Cecco, M., Peterson, A. L., Pagliaroli, L., Manivannan, J., Hubbard, G. B., Ikeno, Y., Zhang, Y., Feng, B., et al. (2015) · Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 293

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

Mao, K., Quipildor, G. F., Tabrizian, T., Novaj, A., Guan, F., Walters, R. O., Delahaye, F., Hubbard, G. B., Ikeno, Y., Ejima, K., et al. (2018) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsGrowth Hormone and Insulin-like Growth Factors

Cited by 167

Adenomyosis in the baboon is associated with primary infertility

Barrier, B. F., Malinowski, M. J., Dick, E. J., Hubbard, G. B., & Bates, G. W. (2004) · Fertility and Sterility

Endometriosis Research and TreatmentGynecological conditions and treatments

Cited by 104

Housing Density Does Not Influence the Longevity Effect of Calorie Restriction

Ikeno, Y., Hubbard, G. B., Lee, S., Richardson, A., Strong, R., Diaz, V., & Nelson, J. F. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 83

Rapamycin Increases Mortality in db/db Mice, a Mouse Model of Type 2 Diabetes

Sataranatarajan, K., Ikeno, Y., Bokov, A., Feliers, D., Yalamanchili, H., Lee, H. J., Mariappan, M. M., Tabatabai-Mir, H., Diaz, V., Prasad, S., et al. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 65

Endothelial senescence after high-cholesterol, high-fat diet challenge in baboons

Shi, Q., Hubbard, G. B., Kushwaha, R. S., Rainwater, D., Thomas, C. A., Leland, M. M., VandeBerg, J. L., & Wang, X. L. (2007) · American Journal of Physiology-Heart and Circulatory Physiology

Telomeres, Telomerase, and SenescenceNitric Oxide and Endothelin Effects

Cited by 43

Protection of non-murine mammals against encephalomyocarditis virus using a genetically engineered Mengo virus

Osorio, J. E., Hubbard, G. B., Soike, K. F., Girard, M., van der Werf, S., Moulin, J.-C., & Palmenberg, A. C. (1996) · Vaccine

Animal Virus Infections StudiesViral Infections and Immunology Research

Cited by 41