Keenan, Daniel M.

Motivations and Methods for Analyzing Pulsatile Hormone Secretion

Veldhuis, J. D., Keenan, D. M., & Pincus, S. M. (2008) · Endocrine Reviews

Hypothalamic control of reproductive hormonesGrowth Hormone and Insulin-like Growth Factors

Cited by 223

A feedback-controlled ensemble model of the stress-responsive hypothalamo-pituitary-adrenal axis.

Keenan, D. M., Licinio, J., & Veldhuis, J. D. (2001) · Proceedings of the National Academy of Sciences

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 145

Sensitivity and specificity of pulse detection using a new deconvolution method

Liu, P. Y., Keenan, D. M., Kok, P., Padmanabhan, V., O'Byrne, K. T., & Veldhuis, J. D. (2009) · American Journal of Physiology-Endocrinology and Metabolism

Hypothalamic control of reproductive hormonesStatistical and numerical algorithms

Cited by 90

Reconstruction of in vivo time-evolving neuroendocrine dose–response properties unveils admixed deterministic and stochastic elements

Keenan, D. M., Alexander, S., Irvine, C. H. G., Clarke, I., Scott, C., Turner, A., Tilbrook, A. J., Canny, B. J., & Veldhuis, J. D. (2004) · Proceedings of the National Academy of Sciences

Stress Responses and CortisolReceptor Mechanisms and Signaling

Cited by 70

An Ensemble Model of the Male Gonadal Axis: Illustrative Application in Aging Men

Keenan, D. M., Takahashi, P. Y., Liu, P. Y., Roebuck, P. D., Nehra, A. X., Iranmanesh, A., & Veldhuis, J. D. (2006) · Endocrinology

Hypothalamic control of reproductive hormonesHormonal and reproductive studies

Cited by 65

Gender, age, body mass index, and IGF-I individually and jointly determine distinct GH dynamics: analyses in one hundred healthy adults

Veldhuis, J. D., Roelfsema, F., Keenan, D. M., & Pincus, S. (2011) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and Treatments

Cited by 53

Basal, Pulsatile, Entropic (Patterned), and Spiky (Staccato-like) Properties of ACTH Secretion: Impact of Age, Gender, and Body Mass Index

Veldhuis, J. D., Roelfsema, F., Iranmanesh, A., Carroll, B. J., Keenan, D. M., & Pincus, S. M. (2009) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 51

Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men

Veldhuis, J. D., Liu, P. Y., Keenan, D. M., & Takahashi, P. Y. (2012) · American Journal of Physiology-Endocrinology and Metabolism

Hypothalamic control of reproductive hormonesHormonal and reproductive studies

Cited by 48

Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men

Keenan, D. M., & Veldhuis, J. D. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 43

Cortisol feedback state governs adrenocorticotropin secretory-burst shape, frequency, and mass in a dual-waveform construct: time of day-dependent regulation

Keenan, D. M., & Veldhuis, J. D. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 41

Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness

Keenan, D. M., Roelfsema, F., Carroll, B. J., Iranmanesh, A., & Veldhuis, J. D. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 41

Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin-like growth factor-I-enforced suppression of endogenously driven GH release in postmenopausal women.

Veldhuis, J. D., Anderson, S. M., Kok, P., Iranmanesh, A., Frystyk, J., Ørskov, H., & Keenan, D. M. (2004) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 34

Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp.

Erickson, D., Keenan, D. M., Mielke, K., Bradford, K., Bowers, C. Y., Miles, J. M., & Veldhuis, J. D. (2004) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 26

Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp

Erickson, D., Keenan, D. M., Farhy, L., Mielke, K., Bowers, C. Y., & Veldhuis, J. D. (2005) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 21