Most cited biochemistry, genetics and molecular biology papers
- Verified
Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy
Lan, Y. Y., Londoño, D., Bouley, R., Rooney, M. S., & Hacohen, N. (2014) · Cell Reports
Autophagy in Disease and TherapySystemic Lupus Erythematosus Research
Cited by 236
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MicroRNA: A novel target of curcumin in cancer therapy
Mirzaei, H., Masoudifar, A., Sahebkar, A., Zare, N., Sadri Nahand, J., Rashidi, B., Mehrabian, E., Mohammadi, M., Mirzaei, H. R., & Jaafari, M. R. (2018) · Journal of Cellular Physiology
Curcumin's Biomedical ApplicationsMicroRNA in disease regulation
Cited by 236
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Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry
Li, B., Raji, I. O., Gordon, A. G. R., Sun, L., Raimondo, T. M., Oladimeji, F. A., Jiang, A. Y., Varley, A., Langer, R. S., & Anderson, D. G. (2024) · Nature Materials
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 236
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Structures of β-klotho reveal a ‘zip code’-like mechanism for endocrine FGF signalling
Lee, S., Choi, J., Mohanty, J., Sousa, L. P., Tome, F., Pardon, E., Steyaert, J., Lemmon, M. A., Lax, I., & Schlessinger, J. (2018) · Nature
Fibroblast Growth Factor ResearchParathyroid Disorders and Treatments
Cited by 236
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Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus
Galigniana, M. D., Radanyi, C., Renoir, J.-M., Housley, P. R., & Pratt, W. B. (2001) · Journal of Biological Chemistry
Signaling Pathways in DiseaseHeat shock proteins research
Cited by 236
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SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities
David, G., Neptune, M. A., & DePinho, R. A. (2002) · Journal of Biological Chemistry
Histone Deacetylase Inhibitors ResearchUbiquitin and proteasome pathways
Cited by 236
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Consequences of Range Contractions and Range Shifts on Molecular Diversity
Arenas, M., Ray, N., Currat, M., & Excoffier, L. (2012) · Molecular Biology and Evolution
Genetic diversity and population structureEvolution and Genetic Dynamics
Cited by 236
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Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells
Hernando-Herraez, I., Evano, B., Stubbs, T., Commere, P.-H., Jan Bonder, M., Clark, S., Andrews, S., Tajbakhsh, S., & Reik, W. (2019) · Nature Communications
Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics
Cited by 236
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Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-κB ligand.
Hikita, A., Yana, I., Wakeyama, H., Nakamura, M., Kadono, Y., Oshima, Y., Nakamura, K., Seiki, M., & Tanaka, S. (2006) · Journal of Biological Chemistry
Bone Metabolism and DiseasesProtease and Inhibitor Mechanisms
Cited by 236
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MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease
Denk, J., Boelmans, K., Siegismund, C., Lassner, D., Arlt, S., & Jahn, H. (2015) · PLOS ONE
MicroRNA in disease regulationAlzheimer's disease research and treatments
Cited by 236
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G‐protein mediated gating of inward‐rectifier K+ channels
Mark, M. D., & Herlitze, S. (2000) · European Journal of Biochemistry
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 236
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Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system
Takeda, K., Cowan, A., & Fong, G.-H. (2007) · Circulation
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 236
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Evolutionary history of the COII/tRNALys intergenic 9 base pair deletion in human mitochondrial DNAs from the Pacific.
Redd, A. J., Takezaki, N., Sherry, S. T., McGarvey, S. T., Sofro, A. S. M., & Stoneking, M. (1995) · Molecular Biology and Evolution
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 236
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eIF2B activator prevents neurological defects caused by a chronic integrated stress response
Wong, Y. L., LeBon, L., Basso, A. M., Kohlhaas, K. L., Nikkel, A. L., Robb, H. M., Donnelly-Roberts, D. L., Prakash, J., Swensen, A. M., Rubinstein, N. D., et al. (2019) · eLife
Endoplasmic Reticulum Stress and DiseaseRNA and protein synthesis mechanisms
Cited by 236
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Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk
Parikka, V., Näntö-Salonen, K., Saarinen, M., Simell, T., Ilonen, J., Hyöty, H., Veijola, R., Knip, M., & Simell, O. (2012) · Diabetologia
Diabetes and associated disordersDiabetes Management and Research
Cited by 235
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A Mitochondrial Oscillator Dependent on Reactive Oxygen Species
Cortassa, S., Aon, M. A., Winslow, R. L., & O’Rourke, B. (2004) · Biophysical Journal
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 235
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The Effect of Hypoxia on Mesenchymal Stem Cell Biology
Ejtehadifar, M., Shamsasenjan, K., Movassaghpour, A., Akbarzadehlaleh, P., Dehdilani, N., Abbasi, P., Molaeipour, Z., & Saleh, M. (2015) · Advanced Pharmaceutical Bulletin
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 235
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A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages
Tchieu, J., Zimmer, B., Fattahi, F., Amin, S., Zeltner, N., Chen, S., & Studer, L. (2017) · Cell Stem Cell
Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation
Cited by 235
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Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data
Chen, S., & Mar, J. C. (2018) · BMC Bioinformatics
Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics
Cited by 235
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Senescence and Cancer: A Review of Clinical Implications of Senescence and Senotherapies
Wyld, L., Bellantuono, I., Tchkonia, T., Morgan, J., Turner, O., Foss, F., George, J., Danson, S., & Kirkland, J. L. (2020) · Cancers
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 235
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MMSplice: modular modeling improves the predictions of genetic variant effects on splicing
Cheng, J., Nguyen, T. Y. D., Cygan, K. J., Çelik, M. H., Fairbrother, W. G., Avsec, Ž., & Gagneur, J. (2019) · Genome Biology
RNA Research and SplicingGenomics and Rare Diseases
Cited by 235
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The spatial dimensions of electrically coupled networks of interneurons in the neocortex
Amitai, Y., Gibson, J. R., Beierlein, M., Patrick, S. L., Ho, A. M., Connors, B. W., & Golomb, D. (2002) · The Journal of Neuroscience
Connexins and lens biologyNeural dynamics and brain function
Cited by 235
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Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates
Hewitson, K. S., Liénard, B. M. R., McDonough, M. A., Clifton, I. J., Butler, D., Soares, A. S., Oldham, N. J., McNeill, L. A., & Schofield, C. J. (2007) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 235
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Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria
Farasat, I., Kushwaha, M., Collens, J., Easterbrook, M., Guido, M., & Salis, H. M. (2014) · Molecular Systems Biology
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 235
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