Most cited biochemistry, genetics and molecular biology papers
- Verified
Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models
Heckmann, D., Lloyd, C. J., Mih, N., Ha, Y., Zielinski, D. C., Haiman, Z. B., Desouki, A. A., Lercher, M. J., & Palsson, B. O. (2018) · Nature Communications
Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks
Cited by 218
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Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway
Fu, Y., Ibrahim, A. S., Sheppard, D. C., Chen, Y., French, S. W., Cutler, J. E., Filler, S. G., & Edwards, J. E. (2002) · Molecular Microbiology
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 218
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Optimization of a degradable polymer–lipid nanoparticle for potent systemic delivery of mRNA to the lung endothelium and immune cells
Kaczmarek, J. C., Kauffman, K. J., Fenton, O. S., Sadtler, K., Patel, A. K., Heartlein, M. W., DeRosa, F., & Anderson, D. G. (2018) · Nano Letters
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 218
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Cellular senescence and apoptosis: how cellular responses might influence aging phenotypes
Campisi, J. (2003) · Experimental Gerontology
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 218
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Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases
Chu, C. T. (2019) · Neurobiology of Disease
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 218
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Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice
Torres, J., Hu, J., Seki, A., Eisele, C., Nair, N., Huang, R., Tarassishin, L., Jharap, B., Cote-Daigneault, J., Mao, Q., et al. (2020) · Gut
Gut microbiota and healthInflammatory Bowel Disease
Cited by 218
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Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein
Lei, Y., Zhang, X., Su, J., Jeong, M., Gundry, M. C., Huang, Y.-H., Zhou, Y., Li, W., & Goodell, M. A. (2017) · Nature Communications
CRISPR and Genetic EngineeringEpigenetics and DNA Methylation
Cited by 218
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Chemistry of Hydrogen Peroxide Formation and Elimination in Mammalian Cells, and Its Role in Various Pathologies
Andrés, C. M. C., Pérez de la Lastra, J. M., Juan, C. A., Plou, F. J., & Pérez-Lebeña, E. (2022) · Stresses
Redox biology and oxidative stressCancer and biochemical research
Cited by 218
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Spondylocheiro Dysplastic Form of the Ehlers-Danlos Syndrome—An Autosomal-Recessive Entity Caused by Mutations in the Zinc Transporter Gene SLC39A13
Giunta, C., Elçioglu, N. H., Albrecht, B., Eich, G., Chambaz, C., Janecke, A. R., Yeowell, H., Weis, M., Eyre, D. R., Kraenzlin, M., et al. (2008) · The American Journal of Human Genetics
Connective tissue disorders researchDermatological and Skeletal Disorders
Cited by 218
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Inhalable dry powder mRNA vaccines based on extracellular vesicles
Popowski, K. D., Moatti, A., Scull, G., Silkstone, D., Lutz, H., López de Juan Abad, B., George, A., Belcher, E., Zhu, D., Mei, X., et al. (2022) · Matter
Extracellular vesicles in diseaseInhalation and Respiratory Drug Delivery
Cited by 218
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Human skeletal muscle aging atlas
Kedlian, V. R., Wang, Y., Liu, T., Chen, X., Bolt, L., Tudor, C., Shen, Z., Fasouli, E. S., Prigmore, E., Kleshchevnikov, V., et al. (2024) · Nature Aging
Muscle Physiology and DisordersSingle-cell and spatial transcriptomics
Cited by 218
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Sociability and motor functions in Shank1 mutant mice
Silverman, J. L., Turner, S. M., Barkan, C. L., Tolu, S. S., Saxena, R., Hung, A. Y., Sheng, M., & Crawley, J. N. (2011) · Brain Research
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 218
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AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling
Pant, S., Sharma, M., Patel, K., Caplan, S., Carr, C. M., & Grant, B. D. (2009) · Nature Cell Biology
Cellular transport and secretionAutophagy in Disease and Therapy
Cited by 218
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ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry
Bierut, L. J., Goate, A. M., Breslau, N., Johnson, E. O., Bertelsen, S., Fox, L., Agrawal, A., Bucholz, K. K., Grucza, R., Hesselbrock, V, et al. (2012) · Molecular Psychiatry
Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes
Cited by 218
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Hypoxia and inflammation are two sides of the same coin
Bartels, K., Grenz, A., & Eltzschig, H. K. (2013) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismImmune Response and Inflammation
Cited by 218
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Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans
Jüttner, J., Szabo, A., Gross-Scherf, B., Morikawa, R. K., Rompani, S. B., Hantz, P., Szikra, T., Esposti, F., Cowan, C. S., Bharioke, A., et al. (2019) · Nature Neuroscience
Virus-based gene therapy researchRetinal Development and Disorders
Cited by 218
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Viral Vector Systems for Gene Therapy: A Comprehensive Literature Review of Progress and Biosafety Challenges
Ghosh, S., Brown, A. M., Jenkins, C., & Campbell, K. (2020) · Applied Biosafety
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 218
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16p11.2 deletion and duplication: characterizing neurologic phenotypes in a large clinically ascertained cohort
Steinman, K. J., Spence, S. J., Ramocki, M. B., Proud, M. B., Kessler, S. K., Marco, E. J., Green Snyder, L., D'Angelo, D., Chen, Q., Chung, W. K., et al. (2016) · American Journal of Medical Genetics Part A
Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders
Cited by 218
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Spatial transcriptomics: Technologies, applications and experimental considerations
Wang, Y., Liu, B., Zhao, G., Lee, Y., Buzdin, A., Mu, X., Zhao, J., Chen, H., & Li, X. (2023) · Genomics
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 218
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Effect of a Concentrated “Inert” Macromolecular Cosolute on the Stability of a Globular Protein with Respect to Denaturation by Heat and by Chaotropes: A Statistical-Thermodynamic Model
Minton, A. P. (2000) · Biophysical Journal
Protein Structure and DynamicsProtein purification and stability
Cited by 218
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Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus
Etz, H., Minh, D. B., Henics, T., Dryla, A., Winkler, B., Triska, C., Boyd, A. P., Söllner, J., Schmidt, W., von Ahsen, U., et al. (2002) · Proceedings of the National Academy of Sciences
vaccines and immunoinformatics approachesAntimicrobial Resistance in Staphylococcus
Cited by 218
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Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity
Akoumianaki, T., Kyrmizi, I., Valsecchi, I., Gresnigt, M. S., Samonis, G., Drakos, E., Boumpas, D., Muszkieta, L., Prevost, M.-C., Kontoyiannis, D. P., et al. (2016) · Cell Host & Microbe
Autophagy in Disease and TherapyAntifungal resistance and susceptibility
Cited by 218
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Lectin-resistant CHO glycosylation mutants
Patnaik, S. K., & Stanley, P. (2006) · Methods in Enzymology
Glycosylation and Glycoproteins ResearchViral Infectious Diseases and Gene Expression in Insects
Cited by 218
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Downregulation of Tonic GABAergic Inhibition in a Mouse Model of Fragile X Syndrome
Curia, G., Papouin, T., Séguéla, P., & Avoli, M. (2009) · Cerebral Cortex
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 218
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