Most cited biochemistry, genetics and molecular biology papers
- Verified
A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat
Xu, R., Wang, Q., & Li, L. (2015) · BMC Genomics
Gut microbiota and healthBioinformatics and Genomic Networks
Cited by 193
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A physical reference state unifies the structure-derived potential of mean force for protein folding and binding
Liu, S., Zhang, C., Zhou, H., & Zhou, Y. (2004) · Proteins Structure Function and Bioinformatics
Protein Structure and DynamicsComputational Drug Discovery Methods
Cited by 193
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New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion
Zagórska, A., Deak, M., Campbell, D. G., Banerjee, S., Hirano, M., Aizawa, S., Prescott, A. R., & Alessi, D. R. (2010) · Science Signaling
Protein Kinase Regulation and GTPase SignalingHippo pathway signaling and YAP/TAZ
Cited by 193
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5-Fluorouracil: A Narrative Review on the Role of Regulatory Mechanisms in Driving Resistance to This Chemotherapeutic Agent
Ghafouri-Fard, S., Abak, A., Tondro Anamag, F., Shoorei, H., Fattahi, F., Javadinia, S. A., Basiri, A., & Taheri, M. (2021) · Frontiers in Oncology
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 193
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Biotechnology of non-Saccharomyces yeasts—the ascomycetes
Johnson, E. A. (2013) · Applied Microbiology and Biotechnology
Fungal and yeast genetics researchMicrobial Metabolic Engineering and Bioproduction
Cited by 193
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The see-through medaka: a fish model that is transparent throughout life
Wakamatsu, Y., Pristyazhnyuk, S., Kinoshita, M., Tanaka, M., & Ozato, K. (2001) · Proceedings of the National Academy of Sciences
Zebrafish Biomedical Research ApplicationsReproductive biology and impacts on aquatic species
Cited by 193
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Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci
Stitzel, M. L., Sethupathy, P., Pearson, D. S., Chines, P. S., Song, L., Erdos, M. R., Welch, R., Parker, S. C. J., Boyle, A. P., Scott, L. J., et al. (2010) · Cell Metabolism
Genomics and Chromatin DynamicsPancreatic function and diabetes
Cited by 193
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The Prognostic Importance of Metastatic Site in Men with Metastatic Castration-resistant Prostate Cancer
Pond, G. R., Sonpavde, G., de Wit, R., Eisenberger, M. A., Tannock, I. F., & Armstrong, A. J. (2014) · European Urology
Prostate Cancer Treatment and ResearchBone health and treatments
Cited by 193
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Autophagy regulates lipid metabolism through selective turnover of NCoR1
Saito, T., Kuma, A., Sugiura, Y., Ichimura, Y., Obata, M., Kitamura, H., Okuda, S., Lee, H.-C., Ikeda, K., Kanegae, Y., et al. (2019) · Nature Communications
Autophagy in Disease and TherapyPeroxisome Proliferator-Activated Receptors
Cited by 193
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A general model to predict small molecule substrates of enzymes based on machine and deep learning
Kroll, A., Ranjan, S., Engqvist, M. K. M., & Lercher, M. J. (2023) · Nature Communications
Machine Learning in BioinformaticsComputational Drug Discovery Methods
Cited by 193
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A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit
Cundell, M. J., Hutter, L. H., Nunes Bastos, R., Poser, E., Holder, J., Mohammed, S., Novak, B., & Barr, F. A. (2016) · Journal of Cell Biology
Microtubule and mitosis dynamicsProtein Tyrosine Phosphatases
Cited by 193
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High Telomerase Activity in Primary Lung Cancers: Association With Increased Cell Proliferation Rates and Advanced Pathologic Stage
Albanell, J., Engelhardt, M., Han, W., Moore, M. A. S., Lonardo, F., Rusch, V., Langenfeld, J., Klimstra, D., Venkatraman, E., & Dmitrovsky, E. (1997) · JNCI Journal of the National Cancer Institute
Telomeres, Telomerase, and SenescenceLung Cancer Research Studies
Cited by 193
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Modeling non-uniformity in short-read rates in RNA-Seq data
Li, J., Jiang, H., & Wong, W. H. (2010) · Genome Biology
Genomics and Phylogenetic StudiesGene expression and cancer classification
Cited by 193
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Isolation and Characterization of Mammalian HDAC10, a Novel Histone Deacetylase
Kao, H.-Y., Lee, C.-H., Komarov, A., Han, C. C., & Evans, R. M. (2002) · Journal of Biological Chemistry
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 193
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Potassium conductances underlying repolarization and after‐hyperpolarization in rat CA1 hippocampal interneurones.
Zhang, L., & McBain, C. J. (1995) · The Journal of Physiology
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 193
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Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma
Miura, S., Mitsuhashi, N., Shimizu, H., Kimura, F., Yoshidome, H., Otsuka, M., Kato, A., Shida, T., Okamura, D., & Miyazaki, M. (2012) · BMC Cancer
Fibroblast Growth Factor ResearchHepatocellular Carcinoma Treatment and Prognosis
Cited by 193
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Mapping of signaling networks through synthetic genetic interaction analysis by RNAi
Horn, T., Sandmann, T., Fischer, B., Axelsson, E., Huber, W., & Boutros, M. (2011) · Nature Methods
Bioinformatics and Genomic NetworksGene Regulatory Network Analysis
Cited by 193
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Structure of the homodimeric androgen receptor ligand-binding domain
Nadal, M., Prekovic, S., Gallastegui, N., Helsen, C., Abella, M., Zielinska, K., Gay, M., Vilaseca, M., Taulès, M., Houtsmuller, A. B., et al. (2017) · Nature Communications
Prostate Cancer Treatment and ResearchProtein Structure and Dynamics
Cited by 193
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Lipid-based nanoparticle formulations for small molecules and RNA drugs
Ickenstein, L. M., & Garidel, P. (2019) · Expert Opinion on Drug Delivery
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 193
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HMGB1 in Development and Diseases of the Central Nervous System
Fang, P., Schachner, M., & Shen, Y.-Q. (2012) · Molecular Neurobiology
Advanced Glycation End Products researchNeuroinflammation and Neurodegeneration Mechanisms
Cited by 193
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Rare variant associations with plasma protein levels in the UK Biobank
Dhindsa, R. S., Burren, O. S., Sun, B. B., Prins, B. P., Matelska, D., Wheeler, E., Mitchell, J., Oerton, E., Hristova, V. A., Smith, K. R., et al. (2023) · Nature
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 193
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In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells
Spelbrink, J. N., Toivonen, J. M., Hakkaart, G. A. J., Kurkela, J. M., Cooper, H. M., Lehtinen, S. K., Lecrenier, N., Back, J. W., Speijer, D., Foury, F., et al. (2000) · Journal of Biological Chemistry
Mitochondrial Function and PathologyDNA Repair Mechanisms
Cited by 193
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Childhood abuse is associated with methylation of multiple loci in adult DNA
Suderman, M., Borghol, N., Pappas, J. J., Pinto Pereira, S. M., Pembrey, M., Hertzman, C., Power, C., & Szyf, M. (2014) · BMC Medical Genomics
Epigenetics and DNA MethylationChild Abuse and Trauma
Cited by 193
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Mesenchymal stem cell-based therapy of inflammatory lung diseases: current understanding and future perspectives
Harrell, C. R., Sadikot, R., Pascual, J., Fellabaum, C., Jankovic, M. G., Jovicic, N., Djonov, V., Arsenijevic, N., & Volarevic, V. (2019) · Stem Cells International
Mesenchymal stem cell researchNeonatal Respiratory Health Research
Cited by 193
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