Most cited biochemistry, genetics and molecular biology papers
- Verified
DNA methylation impacts on learning and memory in aging
Liu, L., van Groen, T., Kadish, I., & Tollefsbol, T. O. (2009) · Neurobiology of Aging
Epigenetics and DNA MethylationMemory and Neural Mechanisms
Cited by 152
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Rhodopsin phosphorylation: 30 years later
Maeda, T. (2003) · Progress in Retinal and Eye Research
Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research
Cited by 152
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Mitochondrial permeability transition pore: Sensitivity to opening and mechanistic dependence on substrate availability
Briston, T., Roberts, M., Lewis, S., Powney, B., M. Staddon, J., Szabadkai, G., & Duchen, M. R. (2017) · Scientific Reports
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 152
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Genetics of Aging in the Fruit Fly,Drosophila melanogaster
Helfand, S. L., & Rogina, B. (2003) · Annual Review of Genetics
Genetics, Aging, and Longevity in Model OrganismsNeurobiology and Insect Physiology Research
Cited by 152
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Peroxisomal d -hydroxyacyl-CoA dehydrogenase deficiency: Resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency
van Grunsven, E. G., van Berkel, E., Ijlst, L., Vreken, P., de Klerk, J. B. C., Adamski, J., Lemonde, H., Clayton, P. T., Cuebas, D. A., & Wanders, R. J. A. (1998) · Proceedings of the National Academy of Sciences
Metabolism and Genetic DisordersNeurological diseases and metabolism
Cited by 152
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Myelodysplastic syndrome unrelated to lentiviral vector in a patient treated with gene therapy for sickle cell disease
Hsieh, M. M., Bonner, M., Pierciey, F. J., Uchida, N., Rottman, J., Demopoulos, L., Schmidt, M., Kanter, J., Walters, M. C., Thompson, A. A., et al. (2020) · Blood Advances
Virus-based gene therapy researchHemoglobinopathies and Related Disorders
Cited by 152
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Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1
Chen, Q., Plasencia, M., Li, Z., Mukherjee, S., Patra, D., Chen, C.-L., Klose, T., Yao, X.-Q., Kossiakoff, A. A., Chang, L., et al. (2021) · Nature
Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling
Cited by 152
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Molecular Analysis of SALL1 Mutations in Townes-Brocks Syndrome
Kohlhase, J., Taschner, P. E. M., Burfeind, P., Pasche, B., Newman, B., Blanck, C., Breuning, M. H., ten Kate, L. P., Maaswinkel-Mooy, P., Mitulla, B., et al. (1999) · The American Journal of Human Genetics
Genomics and Rare DiseasesCongenital limb and hand anomalies
Cited by 152
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An epigenome-wide association study of sex-specific chronological ageing
McCartney, D. L., Zhang, F., Hillary, R. F., Zhang, Q., Stevenson, A. J., Walker, R. M., Bermingham, M. L., Boutin, T., Morris, S. W., Campbell, A., et al. (2020) · Genome Medicine
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 152
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Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy
Vincent, A. M., Edwards, J. L., McLean, L. L., Hong, Y., Cerri, F., Lopez, I., Quattrini, A., & Feldman, E. L. (2010) · Acta Neuropathologica
Mitochondrial Function and PathologyPain Mechanisms and Treatments
Cited by 152
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FlashFry: A fast and flexible tool for large-scale CRISPR target design
McKenna, A., & Shendure, J. (2018) · BMC Biology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 152
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Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
Rusu, V., Hoch, E., Mercader, J. M., Tenen, D. E., Gymrek, M., Hartigan, C. R., DeRan, M., von Grotthuss, M., Fontanillas, P., Spooner, A., et al. (2017) · Cell
Genetic Associations and EpidemiologyMetabolism, Diabetes, and Cancer
Cited by 152
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Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells
Girod, P.-A., Nguyen, D.-Q., Calabrese, D., Puttini, S., Grandjean, M., Martinet, D., Regamey, A., Saugy, D., Beckmann, J. S., Bucher, P., et al. (2007) · Nature Methods
Genomics and Chromatin DynamicsVirus-based gene therapy research
Cited by 152
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Self-Esteem and Social Adjustment in Young Women with Turner Syndrome—Influence of Pubertal Management and Sexuality: Population-Based Cohort Study
Carel, J.-C., Elie, C., Ecosse, E., Tauber, M., Léger, J., Cabrol, S., Nicolino, M., Brauner, R., Chaussain, J.-L., & Coste, J. (2006) · The Journal of Clinical Endocrinology & Metabolism
Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesSexual Differentiation and Disorders
Cited by 152
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A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors
Loboda, A., Nebozhyn, M., Klinghoffer, R., Frazier, J., Chastain, M., Arthur, W., Roberts, B., Zhang, T., Chenard, M., Haines, B., et al. (2010) · BMC Medical Genomics
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 152
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Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
Cao, S., Shrestha, S., Li, J., Yu, X., Chen, J., Yan, F., Ying, G., Gu, C., Wang, L., & Chen, G. (2017) · Scientific Reports
Inflammasome and immune disordersIntracerebral and Subarachnoid Hemorrhage Research
Cited by 152
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Structural basis and regulation of the reductive stress response
Manford, A. G., Mena, E. L., Shih, K. Y., Gee, C. L., McMinimy, R., Martínez-González, B., Sherriff, R., Lew, B., Zoltek, M., Rodríguez-Pérez, F., et al. (2021) · Cell
Ubiquitin and proteasome pathwaysRedox biology and oxidative stress
Cited by 152
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Metformin Targets Multiple Signaling Pathways in Cancer
Lei, Y., Yi, Y., Liu, Y., Liu, X., Keller, E. T., Qian, C.-N., Zhang, J., & Lu, Y. (2017) · Chinese Journal of Cancer
Metabolism, Diabetes, and CancerCancer, Hypoxia, and Metabolism
Cited by 152
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Cell surface targeting of μ-δ opioid receptor heterodimers by RTP4
Décaillot, F. M., Rozenfeld, R., Gupta, A., & Devi, L. A. (2008) · Proceedings of the National Academy of Sciences
Receptor Mechanisms and SignalingNeuropeptides and Animal Physiology
Cited by 152
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ReDU: a framework to find and reanalyze public mass spectrometry data
Jarmusch, A. K., Wang, M., Aceves, C. M., Advani, R. S., Aguirre, S., Aksenov, A. A., Aleti, G., Aron, A. T., Bauermeister, A., Bolleddu, S., et al. (2020) · Nature Methods
Metabolomics and Mass Spectrometry StudiesResearch Data Management Practices
Cited by 152
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Genetic influences on daily intake and meal patterns of humans
de Castro, J. M. (1993) · Physiology & Behavior
Nutrition, Genetics, and DiseaseNutrition, Health and Food Behavior
Cited by 152
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Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus
Merkle, F. T., Neuhausser, W. M., Santos, D., Valen, E., Gagnon, J. A., Maas, K., Sandoe, J., Schier, A. F., & Eggan, K. (2015) · Cell Reports
CRISPR and Genetic EngineeringPluripotent Stem Cells Research
Cited by 152
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Enhanced synapse remodelling as a common phenotype in mouse models of autism
Isshiki, M., Tanaka, S., Kuriu, T., Tabuchi, K., Takumi, T., & Okabe, S. (2014) · Nature Communications
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 152
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A TrkB Small Molecule Partial Agonist Rescues TrkB Phosphorylation Deficits and Improves Respiratory Function in a Mouse Model of Rett Syndrome
Schmid, D. A., Yang, T., Ogier, M., Adams, I., Mirakhur, Y., Wang, Q., Massa, S. M., Longo, F. M., & Katz, D. M. (2012) · The Journal of Neuroscience
Genetics and Neurodevelopmental DisordersNeuroscience of respiration and sleep
Cited by 152
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