Most cited biochemistry, genetics and molecular biology papers
- Verified
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
Saxonov, S., Berg, P., & Brutlag, D. L. (2006) · Proceedings of the National Academy of Sciences
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 1,401
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A survey of human brain transcriptome diversity at the single cell level
Darmanis, S., Sloan, S. A., Zhang, Y., Enge, M., Caneda, C., Shuer, L. M., Hayden Gephart, M. G., Barres, B. A., & Quake, S. R. (2015) · Proceedings of the National Academy of Sciences
Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms
Cited by 1,401
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Frameshift Mutations and the Genetic Code
Streisinger, G., Okada, Y., Emrich, J., Newton, J., Tsugita, A., Terzaghi, E., & Inouye, M. (1966) · Cold Spring Harbor Symposia on Quantitative Biology
RNA and protein synthesis mechanismsEvolution and Genetic Dynamics
Cited by 1,400
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Epigenetic regulation in psychiatric disorders
Tsankova, N., Renthal, W., Kumar, A., & Nestler, E. J. (2007) · Nature reviews. Neuroscience
Epigenetics and DNA MethylationNeuroscience and Neuropharmacology Research
Cited by 1,400
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The impact of translocations and gene fusions on cancer causation
Mitelman, F., Johansson, B., & Mertens, F. (2007) · Nature Reviews Cancer
Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics
Cited by 1,400
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Revisiting Cardiac Cellular Composition
Pinto, A. R., Ilinykh, A., Ivey, M. J., Kuwabara, J. T., D’Antoni, M. L., Debuque, R., Chandran, A., Wang, L., Arora, K., Rosenthal, N. A., et al. (2016) · Circulation Research
Congenital heart defects researchCardiac Fibrosis and Remodeling
Cited by 1,400
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Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
El-Mir, M.-Y., Nogueira, V., Fontaine, E., Avéret, N., Rigoulet, M., & Leverve, X. (2000) · Journal of Biological Chemistry
Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer
Cited by 1,399
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Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child
Schuelke, M., Wagner, K. R., Stolz, L. E., Hübner, C., Riebel, T., Kömen, W., Braun, T., Tobin, J. F., & Lee, S.-J. (2004) · New England Journal of Medicine
Muscle Physiology and DisordersCardiomyopathy and Myosin Studies
Cited by 1,399
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Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.
Burns, J. C., Friedmann, T., Driever, W., Burrascano, M., & Yee, J. K. (1993) · Proceedings of the National Academy of Sciences
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 1,399
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Gut microbial metabolites as multi-kingdom intermediates
Krautkramer, K. A., Fan, J., & Bäckhed, F. (2021) · Nature Reviews Microbiology
Gut microbiota and healthMetabolomics and Mass Spectrometry Studies
Cited by 1,398
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RNA‐binding proteins and post‐transcriptional gene regulation
Glisovic, T., Bachorik, J. L., Yong, J., & Dreyfuss, G. (2008) · FEBS Letters
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 1,398
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Rapid leukocyte migration by integrin-independent flowing and squeezing
Lämmermann, T., Bader, B. L., Monkley, S. J., Worbs, T., Wedlich-Söldner, R., Hirsch, K., Keller, M., Förster, R., Critchley, D. R., Fässler, R., et al. (2008) · Nature
Cellular Mechanics and InteractionsCell Adhesion Molecules Research
Cited by 1,397
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Mitochondrial dynamics: overview of molecular mechanisms
Tilokani, L., Nagashima, S., Paupe, V., & Prudent, J. (2018) · Essays in Biochemistry
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 1,397
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Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
Van Nostrand, E. L., Pratt, G. A., Shishkin, A. A., Gelboin-Burkhart, C., Fang, M. Y., Sundararaman, B., Blue, S. M., Nguyen, T. B., Surka, C., Elkins, K., et al. (2016) · Nature Methods
RNA Research and SplicingGenomics and Chromatin Dynamics
Cited by 1,397
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Mechanotransduction gone awry
Jaalouk, D. E., & Lammerding, J. (2009) · Nature Reviews Molecular Cell Biology
Cellular Mechanics and InteractionsHippo pathway signaling and YAP/TAZ
Cited by 1,396
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Genotype and SNP calling from next-generation sequencing data
Nielsen, R., Paul, J. S., Albrechtsen, A., & Song, Y. S. (2011) · Nature Reviews Genetics
Genomics and Phylogenetic StudiesGenomics and Rare Diseases
Cited by 1,396
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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes.
Reyes-Turcu, F. E., Ventii, K. H., & Wilkinson, K. D. (2009) · Annual Review of Biochemistry
Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors
Cited by 1,396
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Somatic mutation in cancer and normal cells
Martincorena, I., & Campbell, P. J. (2015) · Science
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 1,396
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The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing
Makeyev, E. V., Zhang, J., Carrasco, M. A., & Maniatis, T. (2007) · Molecular Cell
RNA Research and SplicingMicroRNA in disease regulation
Cited by 1,395
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Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Mitsuishi, Y., Taguchi, K., Kawatani, Y., Shibata, T., Nukiwa, T., Aburatani, H., Yamamoto, M., & Motohashi, H. (2012) · Cancer Cell
Genomics, phytochemicals, and oxidative stressCancer, Hypoxia, and Metabolism
Cited by 1,395
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Antiinflammatory Properties of HDL
Barter, P. J., Nicholls, S., Rye, K.-A., Anantharamaiah, G. M., Navab, M., & Fogelman, A. M. (2004) · Circulation Research
Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases
Cited by 1,394
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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
Kabeya, Y., Mizushima, N., Yamamoto, A., Oshitani-Okamoto, S., Ohsumi, Y., & Yoshimori, T. (2004) · Journal of Cell Science
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 1,394
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Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy
Alix-Panabières, C., & Pantel, K. (2016) · Cancer Discovery
Cancer Genomics and DiagnosticsPrenatal Screening and Diagnostics
Cited by 1,394
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Membrane lipid homeostasis in bacteria
Zhang, Y.-M., & Rock, C. O. (2008) · Nature Reviews Microbiology
Lipid metabolism and biosynthesisLipid Membrane Structure and Behavior
Cited by 1,393
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