Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Senescence-associated β-galactosidase is lysosomal β-galactosidase.

Lee, B. Y., Han, J. A., Im, J. S., Morrone, A., Johung, K., Goodwin, E. C., Kleijer, W. J., DiMaio, D., & Hwang, E. S. (2006) · Aging Cell

Telomeres, Telomerase, and SenescenceLysosomal Storage Disorders Research

Cited by 1,444

Nuclear protein CBP is a coactivator for the transcription factor CREB

Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R., & Goodman, R. H. (1994) · Nature

Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase Signaling

Cited by 1,443

The Life History of 21 Breast Cancers

Nik-Zainal, S., Van Loo, P., Wedge, D. C., Alexandrov, L. B., Greenman, C. D., Lau, K. W., Raine, K., Jones, D., Marshall, J., Ramakrishna, M., et al. (2012) · Cell

Cancer Genomics and DiagnosticsCancer Cells and Metastasis

Cited by 1,443

Inflammation and aging: signaling pathways and intervention therapies

Li, X., Li, C., Zhang, W., Wang, Y., Qian, P., & Huang, H. (2023) · Signal Transduction and Targeted Therapy

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,443

Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments

Dabney, J., Knapp, M., Glocke, I., Gansauge, M.-T., Weihmann, A., Nickel, B., Valdiosera, C., García, N., Pääbo, S., Arsuaga, J.-L., et al. (2013) · Proceedings of the National Academy of Sciences

Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology

Cited by 1,443

The current state and future directions of RNAi-based therapeutics

Setten, R. L., Rossi, J. J., & Han, S.-P. (2019) · Nature Reviews Drug Discovery

RNA Interference and Gene DeliveryRNA regulation and disease

Cited by 1,443

Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

Blanco-Míguez, A., Beghini, F., Cumbo, F., McIver, L. J., Thompson, K. N., Zolfo, M., Manghi, P., Dubois, L., Huang, K. D., Thomas, A. M., et al. (2023) · Nature Biotechnology

Genomics and Phylogenetic StudiesGut microbiota and health

Cited by 1,442

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

Raue, A., Kreutz, C., Maiwald, T., Bachmann, J., Schilling, M., Klingmüller, U., & Timmer, J. (2009) · Bioinformatics

Gene Regulatory Network AnalysisControl Systems and Identification

Cited by 1,442

Physiology of cell volume regulation in vertebrates

Hoffmann, E. K., Lambert, I. H., & Pedersen, S. F. (2009) · Physiological Reviews

Ion Transport and Channel RegulationIon channel regulation and function

Cited by 1,441

The mitochondrial basis of aging

Sun, N., Youle, R. J., & Finkel, T. (2016) · Molecular Cell

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 1,441

Induced pluripotent stem cells from a spinal muscular atrophy patient

Ebert, A. D., Yu, J., Rose, F. F., Mattis, V. B., Lorson, C. L., Thomson, J. A., & Svendsen, C. N. (2009) · Nature

Pluripotent Stem Cells ResearchNeurogenetic and Muscular Disorders Research

Cited by 1,441

TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

Lam, J., Takeshita, S., Barker, J. E., Kanagawa, O., Ross, F. P., & Teitelbaum, S. L. (2000) · Journal of Clinical Investigation

Bone Metabolism and DiseasesOsteomyelitis and Bone Disorders Research

Cited by 1,440

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

Herzig, S., Long, F., Jhala, U. S., Hedrick, S., Quinn, R., Bauer, A., Rudolph, D., Schutz, G., Yoon, C., Puigserver, P., et al. (2001) · Nature

Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors

Cited by 1,440

Exercise and associated dietary extremes impact on gut microbial diversity

Clarke, S. F., Murphy, E. F., O'Sullivan, O., Lucey, A. J., Humphreys, M., Hogan, A., Hayes, P., O'Reilly, M., Jeffery, I. B., Wood-Martin, R., et al. (2014) · Gut

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 1,439

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

Macia, L., Tan, J., Vieira, A. T., Leach, K., Stanley, D., Luong, S., Maruya, M., Ian McKenzie, C., Hijikata, A., Wong, C., et al. (2015) · Nature Communications

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 1,439

Centrifuge: rapid and sensitive classification of metagenomic sequences

Kim, D., Song, L., Breitwieser, F. P., & Salzberg, S. L. (2016) · Genome Research

Genomics and Phylogenetic StudiesAlgorithms and Data Compression

Cited by 1,438

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling.

Lee, J., Giordano, S., & Zhang, J. (2012) · Biochemical Journal

Autophagy in Disease and TherapyRedox biology and oxidative stress

Cited by 1,438

Benchmarking atlas-level data integration in single-cell genomics

Luecken, M. D., Büttner, M., Chaichoompu, K., Danese, A., Interlandi, M., Mueller, M. F., Strobl, D. C., Zappia, L., Dugas, M., Colomé-Tatché, M., et al. (2022) · Nature Methods

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 1,438

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

Boulangé, C. L., Neves, A. L., Chilloux, J., Nicholson, J. K., & Dumas, M.-E. (2016) · Genome Medicine

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,438

Structure, function, and formation of biological iron-sulfur clusters

Johnson, D. C., Dean, D. R., Smith, A. D., & Johnson, M. K. (2005) · Annual Review of Biochemistry

Metalloenzymes and iron-sulfur proteinsEnzyme Structure and Function

Cited by 1,438

Estimating the probability of identity among genotypes in natural populations: cautions and guidelines

Waits, L. P., Luikart, G., & Taberlet, P. (2001) · Molecular Ecology

Genetic diversity and population structureForensic and Genetic Research

Cited by 1,437

HMGB1 is a therapeutic target for sterile inflammation and infection

Andersson, U., & Tracey, K. J. (2011) · Annual Review of Immunology

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 1,437

The Application of Ecological Theory Toward an Understanding of the Human Microbiome

Costello, E. K., Stagaman, K., Dethlefsen, L., Bohannan, B. J. M., & Relman, D. A. (2012) · Science

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 1,437

Architecture of the human interactome defines protein communities and disease networks

Huttlin, E. L., Bruckner, R. J., Paulo, J. A., Cannon, J. R., Ting, L., Baltier, K., Colby, G., Gebreab, F., Gygi, M. P., Parzen, H., et al. (2017) · Nature

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 1,437