Most cited biochemistry, genetics and molecular biology papers
- Verified
Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
Wilson, W. H., O'Connor, O. A., Czuczman, M. S., LaCasce, A. S., Gerecitano, J. F., Leonard, J. P., Tulpule, A., Dunleavy, K., Xiong, H., Chiu, Y.-L., et al. (2010) · The Lancet Oncology
Cell death mechanisms and regulationLymphoma Diagnosis and Treatment
Cited by 876
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Thinking about Bacterial Populations as Multicellular Organisms
Shapiro, J. A. (1998) · Annual Review of Microbiology
Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology
Cited by 876
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Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis
Farrell, J. A., Wang, Y., Riesenfeld, S. J., Shekhar, K., Regev, A., & Schier, A. F. (2018) · Science
Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation
Cited by 876
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The genetic architecture of the human cerebral cortex
Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Ching, C. R. K., McMahon, M. A. B., et al. (2020) · Science
Genetic Associations and EpidemiologyCognitive Abilities and Testing
Cited by 876
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R UBISCO : Structure, Regulatory Interactions, and Possibilities for a Better Enzyme
Spreitzer, R. J., & Salvucci, M. E. (2002) · Annual Review of Plant Biology
Photosynthetic Processes and MechanismsEnzyme Structure and Function
Cited by 876
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The chemistry and biological activities of N-acetylcysteine
Samuni, Y., Goldstein, S., Dean, O. M., & Berk, M. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects
Sulfur Compounds in BiologyRedox biology and oxidative stress
Cited by 876
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Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes
Magnúsdóttir, S., Ravcheev, D., de Crécy-Lagard, V., & Thiele, I. (2015) · Frontiers in Genetics
Gut microbiota and healthFolate and B Vitamins Research
Cited by 876
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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity
Urlaub, G., & Chasin, L. A. (1980) · Proceedings of the National Academy of Sciences
Biochemical and Molecular ResearchFolate and B Vitamins Research
Cited by 876
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Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
Jin, S. C., Homsy, J., Zaidi, S., Lu, Q., Morton, S., DePalma, S. R., Zeng, X., Qi, H., Chang, W., Sierant, M. C., et al. (2017) · Nature Genetics
Congenital heart defects researchGenomics and Rare Diseases
Cited by 875
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A survey of sequence alignment algorithms for next-generation sequencing
Li, H., & Homer, N. (2010) · Briefings in Bioinformatics
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 875
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Familial aggregation ofV˙ o 2 max response to exercise training: results from the HERITAGE Family Study
Bouchard, C., An, P., Rice, T., Skinner, J. S., Wilmore, J. H., Gagnon, J., Pérusse, L., Leon, A. S., & Rao, D. C. (1999) · Journal of Applied Physiology
Genetics and Physical PerformanceCardiovascular and exercise physiology
Cited by 875
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The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities
Edwards, J. S., & Palsson, B. O. (2000) · Proceedings of the National Academy of Sciences
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 875
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Recovery of gut microbiota of healthy adults following antibiotic exposure
Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., et al. (2018) · Nature Microbiology
Gut microbiota and healthAntibiotic Resistance in Bacteria
Cited by 875
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The mosaic genome of warm-blooded vertebrates
Bernardi, G., Olofsson, B., Filipski, J., Zerial, M., Salinas, J., Cuny, G., Meunier-Rotival, M., & Rodier, F. (1985) · Science
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 875
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The NCBI BioSystems database
Geer, L. Y., Marchler-Bauer, A., Geer, R. C., Han, L., He, J., He, S., Liu, C., Shi, W., & Bryant, S. H. (2010) · Nucleic Acids Research
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 875
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Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease
Haeggström, J. Z., & Funk, C. D. (2011) · Chemical Reviews
Eicosanoids and Hypertension PharmacologyInflammatory mediators and NSAID effects
Cited by 875
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Clustering huge protein sequence sets in linear time
Steinegger, M., & Söding, J. (2018) · Nature Communications
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 875
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Sacituzumab govitecan-hziy in refractory metastatic triple-negative breast cancer
Bardia, A., Mayer, I. A., Vahdat, L. T., Tolaney, S. M., Isakoff, S. J., Diamond, J. R., O’Shaughnessy, J., Moroose, R. L., Santin, A. D., Abramson, V. G., et al. (2019) · New England Journal of Medicine
Breast Cancer Treatment StudiesAdvanced Breast Cancer Therapies
Cited by 874
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Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome
Hill‐Burns, E. M., Debelius, J. W., Morton, J. T., Wissemann, W. T., Lewis, M. R., Wallen, Z. D., Peddada, S. D., Factor, S. A., Molho, E., Zabetian, C. P., et al. (2017) · Movement Disorders
Gut microbiota and healthParkinson's Disease Mechanisms and Treatments
Cited by 874
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MDC1 is a mediator of the mammalian DNA damage checkpoint
Stewart, G. S., Wang, B., Bignell, C. R., Taylor, A. M. R., & Elledge, S. J. (2003) · Nature
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 874
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An evolutionarily conserved mechanism for controlling the efficiency of protein translation
Tuller, T., Carmi, A., Vestsigian, K., Navon, S., Dorfan, Y., Zaborske, J., Pan, T., Dahan, O., Furman, I., & Pilpel, Y. (2010) · Cell
RNA and protein synthesis mechanismsRNA modifications and cancer
Cited by 874
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d -Amino Acids Trigger Biofilm Disassembly
Kolodkin-Gal, I., Romero, D., Cao, S., Clardy, J., Kolter, R., & Losick, R. (2010) · Science
Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology
Cited by 874
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Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
Kim, H., Rafiuddin-Shah, M., Tu, H.-C., Jeffers, J. R., Zambetti, G. P., Hsieh, J. J.-D., & Cheng, E. H.-Y. (2006) · Nature Cell Biology
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 874
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Depression and cancer: mechanisms and disease progression
Spiegel, D., & Giese-Davis, J. (2003) · Biological Psychiatry
Cancer, Stress, Anesthesia, and Immune ResponseCancer survivorship and care
Cited by 874
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