Most cited biochemistry, genetics and molecular biology papers
- Verified
Comparative Genomics of Centrality and Essentiality in Three Eukaryotic Protein-Interaction Networks
Hahn, M. W., & Kern, A. D. (2005) · Molecular Biology and Evolution
Bioinformatics and Genomic NetworksEvolution and Genetic Dynamics
Cited by 656
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The unfolded protein response signals through high-order assembly of Ire1
Korennykh, A. V., Egea, P. F., Korostelev, A. A., Finer-Moore, J., Zhang, C., Shokat, K. M., Stroud, R. M., & Walter, P. (2009) · Nature
Endoplasmic Reticulum Stress and DiseaseRNA Research and Splicing
Cited by 656
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Methods for Monitoring Autophagy from Yeast to Human
Klionsky, D. J., Cuervo, A. M., & Seglen, P. O. (2007) · Autophagy
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 656
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Machine learning and its applications to biology
Tarca, A. L., Carey, V. J., Chen, X.-W., Romero, R., & Drăghici, S. (2007) · PLoS Computational Biology
Machine Learning in BioinformaticsGenomics and Phylogenetic Studies
Cited by 656
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Widespread Monoallelic Expression on Human Autosomes
Gimelbrant, A., Hutchinson, J. N., Thompson, B. R., & Chess, A. (2007) · Science
Genetic Syndromes and ImprintingGenomics and Chromatin Dynamics
Cited by 655
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Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
Ramakrishna, S., Kwaku Dad, A.-B., Beloor, J., Gopalappa, R., Lee, S.-K., & Kim, H. (2014) · Genome Research
CRISPR and Genetic EngineeringRNA Interference and Gene Delivery
Cited by 655
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Fragile X-related protein and VIG associate with the RNA interference machinery
Caudy, A. A., Myers, M., Hannon, G. J., & Hammond, S. M. (2002) · Genes & Development
RNA Interference and Gene DeliveryRNA Research and Splicing
Cited by 655
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TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
Pilli, M., Arko-Mensah, J., Ponpuak, M., Roberts, E., Master, S., Mandell, M. A., Dupont, N., Ornatowski, W., Jiang, S., Bradfute, S. B., et al. (2012) · Immunity
Autophagy in Disease and TherapyTuberculosis Research and Epidemiology
Cited by 655
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Autophagy mediates degradation of nuclear lamina
Dou, Z., Xu, C., Donahue, G., Shimi, T., Pan, J.-A., Zhu, J., Ivanov, A., Capell, B. C., Drake, A. M., Shah, P. P., et al. (2015) · Nature
Autophagy in Disease and TherapyNuclear Structure and Function
Cited by 655
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Inhalational anesthetics activate two-pore-domain background K+ channels
Patel, A. J., Honoré, E., Lesage, F., Fink, M., Romey, G., & Lazdunski, M. (1999) · Nature Neuroscience
Ion channel regulation and functionAnesthesia and Sedative Agents
Cited by 655
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Complete reconstruction of an enzyme-inhibitor binding process by molecular dynamics simulations
Buch, I., Giorgino, T., & De Fabritiis, G. (2011) · Proceedings of the National Academy of Sciences
Protein Structure and DynamicsComputational Drug Discovery Methods
Cited by 655
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Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells
Farin, H. F., Van Es, J. H., & Clevers, H. (2012) · Gastroenterology
Wnt/β-catenin signaling in development and cancerDigestive system and related health
Cited by 655
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Dystrophin Immunity in Duchenne's Muscular Dystrophy
Mendell, J. R., Campbell, K., Rodino-Klapac, L., Sahenk, Z., Shilling, C., Lewis, S., Bowles, D., Gray, S., Li, C., Galloway, G., et al. (2010) · New England Journal of Medicine
Muscle Physiology and DisordersVirus-based gene therapy research
Cited by 655
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Electrolyte transport in the mammalian colon: mechanisms and implications for disease
Kunzelmann, K., & Mall, M. (2002) · Physiological Reviews
Ion Transport and Channel RegulationCystic Fibrosis Research Advances
Cited by 655
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Variations in GABRA2, Encoding the α2 Subunit of the GABAA Receptor, Are Associated with Alcohol Dependence and with Brain Oscillations
Edenberg, H. J., Dick, D. M., Xuei, X., Tian, H., Almasy, L., Bauer, L. O., Crowe, R. R., Goate, A., Hesselbrock, V., Jones, K., et al. (2004) · The American Journal of Human Genetics
Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior
Cited by 655
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Role of ubiquinone in the mitochondrial generation of hydrogen peroxide
Boveris, A., Cadenas, E., & Stoppani, A. O. M. (1976) · Biochemical Journal
Coenzyme Q10 studies and effectsMitochondrial Function and Pathology
Cited by 655
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Molecular Koch's Postulates Applied to Microbial Pathogenicity
Falkow, S. (1988) · Clinical Infectious Diseases
Bacterial Genetics and BiotechnologyMicrobial infections and disease research
Cited by 655
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Exercise Modifies the Gut Microbiota with Positive Health Effects
Monda, V., Villano, I., Messina, A., Valenzano, A., Esposito, T., Moscatelli, F., Viggiano, A., Cibelli, G., Chieffi, S., Monda, M., et al. (2017) · Oxidative Medicine and Cellular Longevity
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 654
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Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease
Misrani, A., Tabassum, S., & Yang, L. (2021) · Frontiers in Aging Neuroscience
Mitochondrial Function and PathologyAlzheimer's disease research and treatments
Cited by 654
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Multi-omic machine learning predictor of breast cancer therapy response
Sammut, S.-J., Crispin-Ortuzar, M., Chin, S.-F., Provenzano, E., Bardwell, H. A., Ma, W., Cope, W., Dariush, A., Dawson, S.-J., Abraham, J. E., et al. (2022) · Nature
Breast Cancer Treatment StudiesCancer Genomics and Diagnostics
Cited by 654
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Recombinant adeno-associated virus for muscle directed gene therapy
Fisher, K. J., Jooss, K., Alston, J., Yang, Y., Haecker, S. E., High, K., Pathak, R., Raper, S. E., & Wilson, J. M. (1997) · Nature Medicine
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 654
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Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., et al. (2022) · Nature Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 654
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Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
Ohtani, N., Zebedee, Z., Huot, T. J. G., Stinson, J. A., Sugimoto, M., Ohashi, Y., Sharrocks, A. D., Peters, G., & Hara, E. (2001) · Nature
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 654
- Verified
Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
Orjalo, A. V., Bhaumik, D., Gengler, B. K., Scott, G. K., & Campisi, J. (2009) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 654
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