Most cited biochemistry, genetics and molecular biology papers
- Verified
scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
Clark, S. J., Argelaguet, R., Kapourani, C.-A., Stubbs, T. M., Lee, H. J., Alda-Catalinas, C., Krueger, F., Sanguinetti, G., Kelsey, G., Marioni, J. C., et al. (2018) · Nature Communications
Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics
Cited by 657
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Central role of p53 in the suntan response and pathologic hyperpigmentation
Cui, R., Widlund, H. R., Feige, E., Lin, J. Y., Wilensky, D. L., Igras, V. E., D'Orazio, J., Fung, C. Y., Schanbacher, C. F., Granter, S. R., et al. (2007) · Cell
melanin and skin pigmentationSkin Protection and Aging
Cited by 657
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A sensitive assay for dNTPs based on long synthetic oligonucleotides, EvaGreen dye and inhibitor-resistant high-fidelity DNA polymerase
Purhonen, J., Banerjee, R., McDonald, A. E., Fellman, V., & Kallijärvi, J. (2020) · Nucleic Acids Research
Molecular Biology Techniques and ApplicationsDNA and Nucleic Acid Chemistry
Cited by 657
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Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
Bock-Marquette, I., Saxena, A., White, M. D., Michael DiMaio, J., & Srivastava, D. (2004) · Nature
Congenital heart defects researchCardiac Fibrosis and Remodeling
Cited by 657
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Splicing mutations in human genetic disorders: Examples, detection, and confirmation
Anna, A., & Monika, G. (2018) · Journal of Applied Genetics
RNA Research and SplicingGenomics and Rare Diseases
Cited by 657
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Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A., & Hayes, J. D. (2013) · Oncogene
Genomics, phytochemicals, and oxidative stressUbiquitin and proteasome pathways
Cited by 657
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Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue
Zhao, H., Shang, Q., Pan, Z., Bai, Y., Li, Z., Zhang, H., Zhang, Q., Guo, C., Zhang, L., & Wang, Q. (2018) · Diabetes
Extracellular vesicles in diseaseAdipokines, Inflammation, and Metabolic Diseases
Cited by 657
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The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain
Etchevers, H. C., Vincent, C., Douarin, N. M. L., & F. Couly, G. (2001) · Development
Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms
Cited by 657
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Chromatin organization is a major influence on regional mutation rates in human cancer cells
Schuster-Böckler, B., & Lehner, B. (2012) · Nature
Cancer Genomics and DiagnosticsGenomics and Chromatin Dynamics
Cited by 657
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Mapping the proteo-genomic convergence of human diseases
Pietzner, M., Wheeler, E., Carrasco-Zanini, J., Cortes, A., Koprulu, M., Wörheide, M. A., Oerton, E., Cook, J., Stewart, I. D., Kerrison, N. D., et al. (2021) · Science
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 657
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Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications
Rovira-Llopis, S., Bañuls, C., Diaz-Morales, N., Hernandez-Mijares, A., Rocha, M., & Victor, V. M. (2017) · Redox Biology
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 657
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Insights into bilaterian evolution from three spiralian genomes
Simakov, O., Marletaz, F., Cho, S.-J., Edsinger-Gonzales, E., Havlak, P., Hellsten, U., Kuo, D.-H., Larsson, T., Lv, J., Arendt, D., et al. (2013) · Nature
Genomics and Phylogenetic StudiesMarine Invertebrate Physiology and Ecology
Cited by 656
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FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
Demontis, F., & Perrimon, N. (2010) · Cell
Genetics, Aging, and Longevity in Model OrganismsFOXO transcription factor regulation
Cited by 656
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LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus
Finkelshtein, D., Werman, A., Novick, D., Barak, S., & Rubinstein, M. (2013) · Proceedings of the National Academy of Sciences
Virus-based gene therapy researchVirology and Viral Diseases
Cited by 656
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Regulation of cytoplasmic mRNA decay
Schoenberg, D. R., & Maquat, L. E. (2012) · Nature Reviews Genetics
RNA Research and SplicingRNA regulation and disease
Cited by 656
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Fab1p PtdIns(3)P 5-Kinase Function Essential for Protein Sorting in the Multivesicular Body
Odorizzi, G., Babst, M., & Emr, S. D. (1998) · Cell
Cellular transport and secretionFungal and yeast genetics research
Cited by 656
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Advances in the delivery of RNA therapeutics: from concept to clinical reality
Kaczmarek, J. C., Kowalski, P. S., & Anderson, D. G. (2017) · Genome Medicine
RNA Interference and Gene DeliveryRNA Research and Splicing
Cited by 656
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Bmf: A Proapoptotic BH3-Only Protein Regulated by Interaction with the Myosin V Actin Motor Complex, Activated by Anoikis
Puthalakath, H., Villunger, A., O'Reilly, L. A., Beaumont, J. G., Coultas, L., Cheney, R. E., Huang, D. C. S., & Strasser, A. (2001) · Science
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 656
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AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2
Vasudevan, S., & Steitz, J. A. (2007) · Cell
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 656
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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α
Soeda, A., Park, M., Lee, D., Mintz, A., Androutsellis-Theotokis, A., McKay, R. D., Engh, J., Iwama, T., Kunisada, T., Kassam, A. B., et al. (2009) · Oncogene
Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis
Cited by 656
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TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
Chakravarthy, A., Khan, L., Bensler, N. P., Bose, P., & De Carvalho, D. D. (2018) · Nature Communications
TGF-β signaling in diseasesCancer Immunotherapy and Biomarkers
Cited by 656
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Functional annotation of native enhancers with a Cas9–histone demethylase fusion
Kearns, N. A., Pham, H., Tabak, B., Genga, R. M., Silverstein, N. J., Garber, M., & Maehr, R. (2015) · Nature Methods
CRISPR and Genetic EngineeringGenomics and Chromatin Dynamics
Cited by 656
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A DNA methylation atlas of normal human cell types
Loyfer, N., Magenheim, J., Peretz, A., Cann, G., Bredno, J., Klochendler, A., Fox-Fisher, I., Shabi-Porat, S., Hecht, M., Pelet, T., et al. (2023) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 656
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The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
de Lau, W., Peng, W. C., Gros, P., & Clevers, H. (2014) · Genes & Development
Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation
Cited by 656
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