Most cited biochemistry, genetics and molecular biology papers
- Verified
Determinants of BRAF Mutations in Primary Melanomas
Maldonado, J. L., Fridlyand, J., Patel, H., Jain, A. N., Busam, K., Kageshita, T., Ono, T., Albertson, D. G., Pinkel, D., & Bastian, B. C. (2003) · JNCI Journal of the National Cancer Institute
Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management
Cited by 664
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Class II histone deacetylases: versatile regulators
Verdin, E., Dequiedt, F., & Kasler, H. G. (2003) · Trends in Genetics
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 664
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Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data
Dimitrov, D., Türei, D., Garrido-Rodriguez, M., Burmedi, P. L., Nagai, J. S., Boys, C., Ramirez Flores, R. O., Kim, H., Szalai, B., Costa, I. G., et al. (2022) · Nature Communications
Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks
Cited by 664
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Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus: Peroxisomal Proliferator-Activated Receptor Agonists Provide a Rational Therapeutic Approach
Bays, H., Mandarino, L., & DeFronzo, R. A. (2004) · The Journal of Clinical Endocrinology & Metabolism
Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases
Cited by 664
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dPCR: A Technology Review
Quan, P.-L., Sauzade, M., & Brouzes, E. (2018) · Sensors
Molecular Biology Techniques and ApplicationsMicrofluidic and Capillary Electrophoresis Applications
Cited by 664
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Poly(A)-tail profiling reveals an embryonic switch in translational control
Subtelny, A. O., Eichhorn, S. W., Chen, G. R., Sive, H., & Bartel, D. P. (2014) · Nature
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 664
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X-linked adrenoleukodystrophy
Moser, H. W., Mahmood, A., & Raymond, G. V. (2007) · Nature Clinical Practice Neurology
Metabolism and Genetic DisordersLysosomal Storage Disorders Research
Cited by 663
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Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial
Gutzmer, R., Stroyakovskiy, D., Gogas, H., Robert, C., Lewis, K., Protsenko, S., Pereira, R. P., Eigentler, T., Rutkowski, P., Demidov, L., et al. (2020) · The Lancet
Melanoma and MAPK PathwaysCancer Immunotherapy and Biomarkers
Cited by 663
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Elastic fiber homeostasis requires lysyl oxidase–like 1 protein
Liu, X., Zhao, Y., Gao, J., Pawlyk, B., Starcher, B., Spencer, J. A., Yanagisawa, H., Zuo, J., & Li, T. (2004) · Nature Genetics
Connective tissue disorders researchDermatological and Skeletal Disorders
Cited by 663
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The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer
Pomerantz, M. M., Ahmadiyeh, N., Jia, L., Herman, P., Verzi, M. P., Doddapaneni, H., Beckwith, C. A., Chan, J. A., Hills, A., Davis, M., et al. (2009) · Nature Genetics
Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics
Cited by 663
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Crystal structure of metarhodopsin II
Choe, H.-W., Kim, Y. J., Park, J. H., Morizumi, T., Pai, E. F., Krauß, N., Hofmann, K. P., Scheerer, P., & Ernst, O. P. (2011) · Nature
Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research
Cited by 663
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Multiple regions within 8q24 independently affect risk for prostate cancer
Haiman, C. A., Patterson, N., Freedman, M. L., Myers, S. R., Pike, M. C., Waliszewska, A., Neubauer, J., Tandon, A., Schirmer, C., McDonald, G. J., et al. (2007) · Nature Genetics
Genetic Associations and EpidemiologyProstate Cancer Treatment and Research
Cited by 663
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Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
Michael, L. F., Wu, Z., Cheatham, R. B., Puigserver, P., Adelmant, G., Lehman, J. J., Kelly, D. P., & Spiegelman, B. M. (2001) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 663
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Ferritin heavy chain upregulation by NF-κB inhibits TNFα-induced apoptosis by suppressing reactive oxygen species
Pham, C. G., Bubici, C., Zazzeroni, F., Papa, S., Jones, J., Alvarez, K., Jayawardena, S., De Smaele, E., Cong, R., Beaumont, C., et al. (2004) · Cell
NF-κB Signaling PathwaysCell death mechanisms and regulation
Cited by 663
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Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins
Wang, W. (2007) · Nature Reviews Genetics
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 663
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Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles
Kooijmans, S. A. A., Stremersch, S., Braeckmans, K., de Smedt, S. C., Hendrix, A., Wood, M. J. A., Schiffelers, R. M., Raemdonck, K., & Vader, P. (2013) · Journal of Controlled Release
RNA Interference and Gene DeliveryExtracellular vesicles in disease
Cited by 663
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The ClosTron: a universal gene knock-out system for the genus Clostridium
Heap, J. T., Pennington, O. J., Cartman, S. T., Carter, G. P., & Minton, N. P. (2007) · Journal of Microbiological Methods
Bacterial Genetics and BiotechnologyCRISPR and Genetic Engineering
Cited by 663
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Absence of HeLa Cell Contamination in 169 Cell Lines Derived From Human Tumors2
Fogh, J., Wright, W. C., & Loveless, J. D. (1977) · JNCI: Journal of the National Cancer Institute
Cancer and biochemical researchViral Infectious Diseases and Gene Expression in Insects
Cited by 663
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The diverse functions of GAPDH: Views from different subcellular compartments
Tristan, C., Shahani, N., Sedlak, T. W., & Sawa, A. (2011) · Cellular Signalling
Redox biology and oxidative stressCell death mechanisms and regulation
Cited by 663
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Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: In vitro and in vivo evaluations
Kim, M. S., Haney, M. J., Zhao, Y., Yuan, D., Deygen, I., Klyachko, N. L., Kabanov, A. V., & Batrakova, E. V. (2018) · Nanomedicine Nanotechnology Biology and Medicine
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 663
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Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
Grünewald, J., Zhou, R., Garcia, S. P., Iyer, S., Lareau, C. A., Aryee, M. J., & Joung, J. K. (2019) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 663
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Noise in Gene Expression Determines Cell Fate in Bacillus subtilis
Maamar, H., Raj, A., & Dubnau, D. (2007) · Science
Gene Regulatory Network AnalysisBacterial Genetics and Biotechnology
Cited by 663
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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1α-degradative pathway
Isaacs, J. S., Jung, Y.-J., Mimnaugh, E. G., Martinez, A., Cuttitta, F., & Neckers, L. M. (2002) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismHeat shock proteins research
Cited by 663
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Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids
Martinez-Guryn, K., Hubert, N., Frazier, K., Urlass, S., Musch, M. W., Ojeda, P., Pierre, J. F., Miyoshi, J., Sontag, T. J., Cham, C. M., et al. (2018) · Cell Host & Microbe
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 663
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