Most cited biochemistry, genetics and molecular biology papers
- Verified
AMPK is a direct adenylate charge-regulated protein kinase
Oakhill, J. S., Steel, R., Chen, Z.-P., Scott, J. W., Ling, N., Tam, S., & Kemp, B. E. (2011) · Science
Metabolism, Diabetes, and CancerBiochemical and Molecular Research
Cited by 612
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Estimating and interpreting F ST : The impact of rare variants
Bhatia, G., Patterson, N., Sankararaman, S., & Price, A. L. (2013) · Genome Research
Genetic diversity and population structureGenetic Associations and Epidemiology
Cited by 612
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C. Genetics of Man Enzyme polymorphisms in man
Harris, H. (1966) · Proceedings of the Royal Society of London. Series B. Biological Sciences
Genetic Associations and EpidemiologyGenetic diversity and population structure
Cited by 611
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Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing
Shin, C., Nam, J.-W., Farh, K. K.-H., Chiang, H. R., Shkumatava, A., & Bartel, D. P. (2010) · Molecular Cell
MicroRNA in disease regulationRNA Interference and Gene Delivery
Cited by 611
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Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion
Horai, R., Asano, M., Sudo, K., Kanuka, H., Suzuki, M., Nishihara, M., Takahashi, M., & Iwakura, Y. (1998) · The Journal of Experimental Medicine
Inflammasome and immune disordersThermal Regulation in Medicine
Cited by 611
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Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1
Kelly, B. D., Hackett, S. F., Hirota, K., Oshima, Y., Cai, Z., Berg-Dixon, S., Rowan, A., Yan, Z., Campochiaro, P. A., & Semenza, G. L. (2003) · Circulation Research
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 611
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Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs
Kim, D.-H., Lipke, E. A., Kim, P., Cheong, R., Thompson, S., Delannoy, M., Suh, K.-Y., Tung, L., & Levchenko, A. (2010) · Proceedings of the National Academy of Sciences
Cellular Mechanics and InteractionsTissue Engineering and Regenerative Medicine
Cited by 611
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Developmentally Regulated Mitochondrial Fusion Mediated by a Conserved, Novel, Predicted GTPase
Hales, K. G., & Fuller, M. T. (1997) · Cell
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 611
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Role of carnitine in disease
Flanagan, J. L., Simmons, P. A., Vehige, J., Willcox, M. D., & Garrett, Q. (2010) · Nutrition & Metabolism
Metabolism and Genetic DisordersClinical Nutrition and Gastroenterology
Cited by 611
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Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels
Cahenzli, J., Köller, Y., Wyss, M., Geuking, M. B., & McCoy, K. D. (2013) · Cell Host & Microbe
Gut microbiota and healthFood Allergy and Anaphylaxis Research
Cited by 611
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Inhibition of HIF2α Is Sufficient to Suppress pVHL-Defective Tumor Growth
Kondo, K., Kim, W. Y., Lechpammer, M., & Kaelin, W. G. (2003) · PLoS Biology
Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment
Cited by 611
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Why are tumour blood vessels abnormal and why is it important to know?
Nagy, J. A., Chang, S.-H., Dvorak, A. M., & Dvorak, H. F. (2009) · British Journal of Cancer
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 611
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The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents
Siemann, D. W. (2011) · Cancer Treatment Reviews
Angiogenesis and VEGF in CancerHeterocyclic Compound Synthesis and Bioactivity
Cited by 611
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Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
Kleinstiver, B. P., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Topkar, V. V., Zheng, Z., & Joung, J. K. (2015) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 611
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Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD
Mizumura, K., Cloonan, S. M., Nakahira, K., Bhashyam, A. R., Cervo, M., Kitada, T., Glass, K., Owen, C. A., Mahmood, A., Washko, G. R., et al. (2014) · Journal of Clinical Investigation
Autophagy in Disease and TherapyChronic Obstructive Pulmonary Disease (COPD) Research
Cited by 611
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The influence of the microbiome on respiratory health
Wypych, T. P., Wickramasinghe, L. C., & Marsland, B. J. (2019) · Nature Immunology
Gut microbiota and healthAsthma and respiratory diseases
Cited by 611
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Fine-mapping inflammatory bowel disease loci to single-variant resolution
International Inflammatory Bowel Disease Genetics Consortium, Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., et al. (2017) · Nature
Genetic Associations and EpidemiologyInflammatory Bowel Disease
Cited by 611
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Chemical etiology of nucleic acid structure
Eschenmoser, A. (1999) · Science
RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry
Cited by 611
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Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation
Bartke, T., Vermeulen, M., Xhemalce, B., Robson, S. C., Mann, M., & Kouzarides, T. (2010) · Cell
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 611
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The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3
Guenther, M. G., Barak, O., & Lazar, M. A. (2001) · Molecular and Cellular Biology
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 611
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Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
Mochida, K., Oikawa, Y., Kimura, Y., Kirisako, H., Hirano, H., Ohsumi, Y., & Nakatogawa, H. (2015) · Nature
Autophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease
Cited by 611
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An EB1-binding motif acts as a microtubule tip localization signal
Honnappa, S., Gouveia, S. M., Weisbrich, A., Damberger, F. F., Bhavesh, N. S., Jawhari, H., Grigoriev, I., van Rijssel, F. J. A., Buey, R. M., Lawera, A., et al. (2009) · Cell
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 611
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Bile acids as carcinogens in human gastrointestinal cancers
Bernstein, H., Bernstein, C., Payne, C. M., Dvorakova, K., & Garewal, H. (2005) · Mutation Research/Reviews in Mutation Research
Carcinogens and Genotoxicity AssessmentCholangiocarcinoma and Gallbladder Cancer Studies
Cited by 611
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Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals.
Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., LeBrasseur, N. K., Yan, Z., & Spiegelman, B. M. (2007) · Journal of Biological Chemistry
Muscle Physiology and DisordersAdipose Tissue and Metabolism
Cited by 611
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