Most cited biochemistry, genetics and molecular biology papers
- Verified
Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death
Duchen, M. R. (1999) · The Journal of Physiology
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 610
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Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals
Yin, R., Mao, S.-Q., Zhao, B., Chong, Z., Yang, Y., Zhao, C., Zhang, D., Huang, H., Gao, J., Li, Z., et al. (2013) · Journal of the American Chemical Society
Epigenetics and DNA MethylationMetal-Catalyzed Oxygenation Mechanisms
Cited by 609
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Past, present, and future of CRISPR genome editing technologies
Pacesa, M., Pelea, O., & Jinek, M. (2024) · Cell
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 609
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Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System
Hogan, D. J., Riordan, D. P., Gerber, A. P., Herschlag, D., & Brown, P. O. (2008) · PLoS Biology
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 609
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Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056
Jacquemont, S., Curie, A., des Portes, V., Torrioli, M. G., Berry-Kravis, E., Hagerman, R. J., Ramos, F. J., Cornish, K., He, Y., Paulding, C., et al. (2011) · Science Translational Medicine
Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases
Cited by 609
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SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
Tokunaga, F., Nakagawa, T., Nakahara, M., Saeki, Y., Taniguchi, M., Sakata, S.-I., Tanaka, K., Nakano, H., & Iwai, K. (2011) · Nature
NF-κB Signaling PathwaysUbiquitin and proteasome pathways
Cited by 609
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The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP
Napoli, I., Mercaldo, V., Boyl, P. P., Eleuteri, B., Zalfa, F., De Rubeis, S., Di Marino, D., Mohr, E., Massimi, M., Falconi, M., et al. (2008) · Cell
Genetics and Neurodevelopmental DisordersRNA and protein synthesis mechanisms
Cited by 609
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Skin Lipids: Their Biochemical Uniqueness: Unlike internal organs, the skin biosynthesizes and excretes unusual fat soluble substances.
Nicolaides, N. (1974) · Science
Lipid metabolism and biosynthesisCholesterol and Lipid Metabolism
Cited by 609
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Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules
Verhey, K. J., Meyer, D., Deehan, R., Blenis, J., Schnapp, B. J., Rapoport, T. A., & Margolis, B. (2001) · The Journal of Cell Biology
Microtubule and mitosis dynamicsProtein Kinase Regulation and GTPase Signaling
Cited by 609
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Telomere shortening in atherosclerosis
Samani, N. J., Boultby, R., Butler, R., Thompson, J. R., & Goodall, A. H. (2001) · The Lancet
Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases
Cited by 609
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Structure and Function of Human Matrix Metalloproteinases
Laronha, H., & Caldeira, J. (2020) · Cells
Protease and Inhibitor MechanismsBone and Dental Protein Studies
Cited by 609
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PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.
Ogawa, E., Maruyama, M., Kagoshima, H., Inuzuka, M., Lu, J., Satake, M., Shigesada, K., & Ito, Y. (1993) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research
Cited by 608
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Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
Carreira, S., Goodall, J., Denat, L., Rodriguez, M., Nuciforo, P., Hoek, K. S., Testori, A., Larue, L., & Goding, C. R. (2006) · Genes & Development
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 608
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Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria
Balwani, M., Sardh, E., Ventura, P., Peiró, P. A., Rees, D. C., Stölzel, U., Bissell, D. M., Bonkovsky, H. L., Windyga, J., Anderson, K. E., et al. (2020) · New England Journal of Medicine
Porphyrin Metabolism and DisordersNeonatal Health and Biochemistry
Cited by 608
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Scanning Human Gene Deserts for Long-Range Enhancers
Nobrega, M. A., Ovcharenko, I., Afzal, V., & Rubin, E. M. (2003) · Science
Genomics and Chromatin DynamicsCancer-related molecular mechanisms research
Cited by 608
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Single-nucleus and single-cell transcriptomes compared in matched cortical cell types
Bakken, T. E., Hodge, R. D., Miller, J. A., Yao, Z., Nguyen, T. N., Aevermann, B., Barkan, E., Bertagnolli, D., Casper, T., Dee, N., et al. (2018) · PLoS ONE
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 608
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Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis
Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E., & Wakefield, S. (2017) · Clinics and Practice
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 608
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DNA analysis of an early modern human from Tianyuan Cave, China
Fu, Q., Meyer, M., Gao, X., Stenzel, U., Burbano, H. A., Kelso, J., & Pääbo, S. (2013) · Proceedings of the National Academy of Sciences
Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology
Cited by 608
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The knockout mouse project
The Comprehensive Knockout Mouse Project Consortium (2004) · Nature Genetics
Animal Genetics and ReproductionCRISPR and Genetic Engineering
Cited by 608
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Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs
Collino, F., Deregibus, M. C., Bruno, S., Sterpone, L., Aghemo, G., Viltono, L., Tetta, C., & Camussi, G. (2010) · PLoS ONE
Extracellular vesicles in diseaseMicroRNA in disease regulation
Cited by 608
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Structural Evidence for Ligand Specificity in the Binding Domain of the Human Androgen Receptor
Matias, P. M., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A., et al. (2000) · Journal of Biological Chemistry
Prostate Cancer Treatment and ResearchEstrogen and related hormone effects
Cited by 608
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Sequence signatures and mRNA concentration can explain two‐thirds of protein abundance variation in a human cell line
Vogel, C., de Sousa Abreu, R., Ko, D., Le, S., Shapiro, B. A., Burns, S. C., Sandhu, D., Boutz, D. R., Marcotte, E. M., & Penalva, L. O. (2010) · Molecular Systems Biology
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 608
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Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
Guan, Y., Hao, C., Cha, D. R., Rao, R., Lu, W., Kohan, D. E., Magnuson, M. A., Redha, R., Zhang, Y., & Breyer, M. D. (2005) · Nature Medicine
Peroxisome Proliferator-Activated ReceptorsIon Transport and Channel Regulation
Cited by 608
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Complete subunit architecture of the proteasome regulatory particle
Lander, G. C., Estrin, E., Matyskiela, M. E., Bashore, C., Nogales, E., & Martin, A. (2012) · Nature
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 608
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