Most cited biochemistry, genetics and molecular biology papers
- Verified
Insulin resistance and cancer risk: An overview of the pathogenetic mechanisms
Arcidiacono, B., Iiritano, S., Nocera, A., Possidente, K., Nevolo, M. T., Ventura, V., Foti, D., Chiefari, E., & Brunetti, A. (2012) · Experimental Diabetes Research
Metabolism, Diabetes, and CancerCancer Risks and Factors
Cited by 606
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Pervasive Sharing of Genetic Effects in Autoimmune Disease
Cotsapas, C., Voight, B. F., Rossin, E., Lage, K., Neale, B. M., Wallace, C., Abecasis, G. R., Barrett, J. C., Behrens, T., Cho, J., et al. (2011) · PLoS Genetics
Genetic Associations and EpidemiologyMultiple Sclerosis Research Studies
Cited by 606
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MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road
Caunt, C. J., Sale, M. J., Smith, P. D., & Cook, S. J. (2015) · Nature Reviews Cancer
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 606
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Carboxypeptidase A
Christianson, D. W., & Lipscomb, W. N. (1989) · Accounts of Chemical Research
Peptidase Inhibition and AnalysisProtease and Inhibitor Mechanisms
Cited by 606
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Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation
Mansfield, K. D., Guzy, R. D., Pan, Y., Young, R. M., Cash, T. P., Schumacker, P. T., & Simon, M. C. (2005) · Cell Metabolism
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress
Cited by 606
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Taking a good look at free radicals in the aging process
Hekimi, S., Lapointe, J., & Wen, Y. (2011) · Trends in Cell Biology
Genetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology
Cited by 606
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Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells
Galon, J., Franchimont, D., Hiroi, N., Frey, G., Boettner, A., Ehrhart-Bornstein, M., O’shea, J. J., Chrousos, G. P., & Bornstein, S. R. (2002) · The FASEB Journal
Estrogen and related hormone effectsAdrenal Hormones and Disorders
Cited by 606
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The multiple functions and mechanisms of osteopontin
Icer, M. A., & Gezmen-Karadag, M. (2018) · Clinical Biochemistry
Bone and Dental Protein StudiesS100 Proteins and Annexins
Cited by 606
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Aconitase as iron–sulfur protein, enzyme, and iron-regulatory protein
Beinert, H., Kennedy, M. C., & Stout, C. D. (1996) · Chemical Reviews
Metalloenzymes and iron-sulfur proteinsEnzyme Structure and Function
Cited by 606
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Mechanisms and Implications of Metabolic Heterogeneity in Cancer
Kim, J., & DeBerardinis, R. J. (2019) · Cell Metabolism
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 606
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In Embryonic Stem Cells, ZFP57/KAP1 Recognize a Methylated Hexanucleotide to Affect Chromatin and DNA Methylation of Imprinting Control Regions
Quenneville, S., Verde, G., Corsinotti, A., Kapopoulou, A., Jakobsson, J., Offner, S., Baglivo, I., Pedone, P. V., Grimaldi, G., Riccio, A., et al. (2011) · Molecular Cell
Genetic Syndromes and ImprintingEpigenetics and DNA Methylation
Cited by 606
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Osteoprotection by semaphorin 3A
Hayashi, M., Nakashima, T., Taniguchi, M., Kodama, T., Kumanogoh, A., & Takayanagi, H. (2012) · Nature
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 606
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Diet and the Intestinal Microbiome: Associations, Functions, and Implications for Health and Disease
Albenberg, L. G., & Wu, G. D. (2014) · Gastroenterology
Gut microbiota and healthNutritional Studies and Diet
Cited by 606
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COFACTOR: improved protein function prediction by combining structure, sequence and protein–protein interaction information
Zhang, C., Freddolino, L., & Zhang, Y. (2017) · Nucleic Acids Research
Protein Structure and DynamicsBioinformatics and Genomic Networks
Cited by 606
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 606
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IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1
Sacheck, J. M., Ohtsuka, A., McLary, S. C., & Goldberg, A. L. (2004) · American Journal of Physiology-Endocrinology and Metabolism
Muscle Physiology and DisordersMuscle metabolism and nutrition
Cited by 606
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From bulk, single-cell to spatial RNA sequencing
Li, X., & Wang, C.-Y. (2021) · International Journal of Oral Science
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 605
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Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery
Antimisiaris, S. G., Mourtas, S., & Marazioti, A. (2018) · Pharmaceutics
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 605
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Germline gain-of-function mutations in SOS1 cause Noonan syndrome
Roberts, A. E., Araki, T., Swanson, K. D., Montgomery, K. T., Schiripo, T. A., Joshi, V. A., Li, L., Yassin, Y., Tamburino, A. M., Neel, B. G., et al. (2007) · Nature Genetics
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 605
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Secondary Structure of Vertebrate Telomerase RNA
Chen, J.-L., Blasco, M. A., & Greider, C. W. (2000) · Cell
Telomeres, Telomerase, and SenescenceRNA and protein synthesis mechanisms
Cited by 605
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Natural selection has driven population differentiation in modern humans
Barreiro, L. B., Laval, G., Quach, H., Patin, E., & Quintana-Murci, L. (2008) · Nature Genetics
Forensic and Genetic ResearchEvolution and Genetic Dynamics
Cited by 605
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Psychological influences on surgical recovery: Perspectives from psychoneuroimmunology.
Kiecolt-Glaser, J. K., Page, G. G., Marucha, P. T., MacCallum, R. C., & Glaser, R. (1998) · American Psychologist
Cancer, Stress, Anesthesia, and Immune ResponseStress Responses and Cortisol
Cited by 605
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Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria
Isabella, V. M., Ha, B. N., Castillo, M. J., Lubkowicz, D. J., Rowe, S. E., Millet, Y. A., Anderson, C. L., Li, N., Fisher, A. B., West, K. A., et al. (2018) · Nature Biotechnology
Bacterial Cancer TherapyProbiotics and Fermented Foods
Cited by 605
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A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice
Enard, W., Gehre, S., Hammerschmidt, K., Hölter, S. M., Blass, T., Somel, M., Brückner, M. K., Schreiweis, C., Winter, C., Sohr, R., et al. (2009) · Cell
Genetics and Neurodevelopmental DisordersAnimal Vocal Communication and Behavior
Cited by 605
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