Most cited biochemistry, genetics and molecular biology papers
- Verified
Cytokine Stimulation Promotes Glucose Uptake via Phosphatidylinositol-3 Kinase/Akt Regulation of Glut1 Activity and Trafficking
Wieman, H. L., Wofford, J. A., & Rathmell, J. C. (2007) · Molecular Biology of the Cell
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 593
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A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness
O'Connell, J., Gurdasani, D., Delaneau, O., Pirastu, N., Ulivi, S., Cocca, M., Traglia, M., Huang, J., Huffman, J. E., Rudan, I., et al. (2014) · PLoS Genetics
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 593
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DAP‐kinase‐mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl‐XL and induction of autophagy
Zalckvar, E., Berissi, H., Mizrachy, L., Idelchuk, Y., Koren, I., Eisenstein, M., Sabanay, H., Pinkas‐Kramarski, R., & Kimchi, A. (2009) · The EMBO Reports
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 592
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DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
Tarallo, V., Hirano, Y., Gelfand, B. D., Dridi, S., Kerur, N., Kim, Y., Cho, W. G., Kaneko, H., Fowler, B. J., Bogdanovich, S., et al. (2012) · Cell
Inflammasome and immune disordersRetinal Diseases and Treatments
Cited by 592
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Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity
Chen, R., Wu, X., Jiang, L., & Zhang, Y. (2017) · Cell Reports
Single-cell and spatial transcriptomicsRegulation of Appetite and Obesity
Cited by 592
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Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics
Harris, T. B., Launer, L. J., Eiriksdottir, G., Kjartansson, O., Jonsson, P. V., Sigurdsson, G., Thorgeirsson, G., Aspelund, T., Garcia, M. E., Cotch, M. F., et al. (2007) · American Journal of Epidemiology
Genetic Associations and EpidemiologyHealth, Environment, Cognitive Aging
Cited by 592
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Physicochemical modelling of cell signalling pathways
Aldridge, B. B., Burke, J. M., Lauffenburger, D. A., & Sorger, P. K. (2006) · Nature Cell Biology
Gene Regulatory Network AnalysisBioinformatics and Genomic Networks
Cited by 592
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Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma
Jensen, S. A., Day, E. S., Ko, C. H., Hurley, L. A., Luciano, J. P., Kouri, F. M., Merkel, T. J., Luthi, A. J., Patel, P. C., Cutler, J. I., et al. (2013) · Science Translational Medicine
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 592
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Metabolomics enables precision medicine: “A White Paper, Community Perspective”
for “Precision Medicine and Pharmacometabolomics Task Group”-Metabolomics Society Initiative, Beger, R. D., Dunn, W., Schmidt, M. A., Gross, S. S., Kirwan, J. A., Cascante, M., Brennan, L., Wishart, D. S., Oresic, M., et al. (2016) · Metabolomics
Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging
Cited by 592
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Frequency of 22q11 deletions in patients with conotruncal defects
Goldmuntz, E., Clark, B. J., Mitchell, L. E., Jawad, A. F., Cuneo, B. F., Reed, L., McDonald-McGinn, D., Chien, P., Feuer, J., Zackai, E. H., et al. (1998) · Journal of the American College of Cardiology
Genomic variations and chromosomal abnormalitiesCongenital Heart Disease Studies
Cited by 592
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Strains and Strategies for Large-Scale Gene Deletion Studies of the Diploid Human Fungal Pathogen Candida albicans
Noble, S. M., & Johnson, A. D. (2005) · Eukaryotic Cell
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 592
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Lipid nanoparticles enabling gene therapies: from concepts to clinical utility
Kulkarni, J. A., Cullis, P. R., & van der Meel, R. (2018) · Nucleic Acid Therapeutics
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 592
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Active human retrotransposons: variation and disease
Hancks, D. C., & Kazazian, H. H. (2012) · Current Opinion in Genetics & Development
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 592
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Interventions to slow aging in humans: are we ready?
Longo, V. D., Antebi, A., Bartke, A., Barzilai, N., Brown‐Borg, H. M., Caruso, C., Curiel, T. J., Cabo, R., Franceschi, C., Gems, D., et al. (2015) · Aging Cell
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 592
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Current challenges and best-practice protocols for microbiome analysis
Bharti, R., & Grimm, D. G. (2021) · Briefings in Bioinformatics
Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology
Cited by 592
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Metabolic engineering of Escherichia coli for the production of l -valine based on transcriptome analysis and in silico gene knockout simulation
Park, J. H., Lee, K. H., Kim, T. Y., & Lee, S. Y. (2007) · Proceedings of the National Academy of Sciences
Microbial Metabolic Engineering and BioproductionBacterial Genetics and Biotechnology
Cited by 592
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PDGFRαα Signaling Is Regulated through the Primary Cilium in Fibroblasts
Schneider, L., Clement, C. A., Teilmann, S. C., Pazour, G. J., Hoffmann, E. K., Satir, P., & Christensen, S. T. (2005) · Current Biology
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 592
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Joint probabilistic modeling of single-cell multi-omic data with totalVI
Gayoso, A., Steier, Z., Lopez, R., Regier, J., Nazor, K. L., Streets, A., & Yosef, N. (2021) · Nature Methods
Single-cell and spatial transcriptomicsGene Regulatory Network Analysis
Cited by 592
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The SIF binding element confers sis/PDGF inducibility onto the c‐fos promoter.
Wagner, B. J., Hayes, T. E., Hoban, C. J., & Cochran, B. H. (1990) · The EMBO Journal
Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase Signaling
Cited by 592
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Pluripotent stem cells in disease modelling and drug discovery
Avior, Y., Sagi, I., & Benvenisty, N. (2016) · Nature Reviews Molecular Cell Biology
Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering
Cited by 592
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Gut-Microbiota-Brain Axis and Its Effect on Neuropsychiatric Disorders With Suspected Immune Dysregulation
Petra, A. I., Panagiotidou, S., Hatziagelaki, E., Stewart, J. M., Conti, P., & Theoharides, T. C. (2015) · Clinical Therapeutics
Gut microbiota and healthTryptophan and brain disorders
Cited by 592
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THE BIOLOGY OF THE (6–4) PHOTOPRODUCT
MITCHELL, D. L., & NAIRN, R. S. (1989) · Photochemistry and Photobiology
DNA Repair MechanismsCarcinogens and Genotoxicity Assessment
Cited by 592
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Ceramide Generation Is Sufficient to Account for the Inhibition of the Insulin-stimulated PKB Pathway in C2C12 Skeletal Muscle Cells Pretreated with Palmitate
Schmitz-Peiffer, C., Craig, D. L., & Biden, T. J. (1999) · Journal of Biological Chemistry
Sphingolipid Metabolism and SignalingMetabolism, Diabetes, and Cancer
Cited by 592
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Atomic structure of the MAP kinase ERK2 at 2.3 A resolution
Zhang, F., Strand, A., Robbins, D., Cobb, M. H., & Goldsmith, E. J. (1994) · Nature
Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics
Cited by 592
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