Most cited biochemistry, genetics and molecular biology papers
- Verified
Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor inhibiting HIF-1
Umezu, T., Tadokoro, H., Azuma, K., Yoshizawa, S., Ohyashiki, K., & Ohyashiki, J. H. (2014) · Blood
Extracellular vesicles in diseaseMultiple Myeloma Research and Treatments
Cited by 600
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Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins
Li, C., Ullrich, B., Zhang, J. Z., Anderson, R. G. W., Brose, N., & Südhof, T. C. (1995) · Nature
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 599
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Endocytosis unplugged: Multiple ways to enter the cell
Kumari, S., MG, S., & Mayor, S. (2010) · Cell Research
Cellular transport and secretionAutophagy in Disease and Therapy
Cited by 599
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Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
Hart, T., Tong, A. H. Y., Chan, K., Van Leeuwen, J., Seetharaman, A., Aregger, M., Chandrashekhar, M., Hustedt, N., Seth, S., Noonan, A., et al. (2017) · G3 Genes|Genomes|Genetics
CRISPR and Genetic EngineeringRNA Interference and Gene Delivery
Cited by 599
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The effect of curcumin (turmeric) on Alzheimer’s disease: An overview
Mishra, S., & Palanivelu, K. (2008) · Annals of Indian Academy of Neurology
Curcumin's Biomedical ApplicationsAlzheimer's disease research and treatments
Cited by 599
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Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.
Shweiki, D., Neeman, M., Itin, A., & Keshet, E. (1995) · Proceedings of the National Academy of Sciences
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 599
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Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration
Shiva, S., Huang, Z., Grubina, R., Sun, J., Ringwood, L. A., MacArthur, P. H., Xu, X., Murphy, E., Darley-Usmar, V. M., & Gladwin, M. T. (2007) · Circulation Research
Hemoglobin structure and functionNitric Oxide and Endothelin Effects
Cited by 599
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Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis
Mohrin, M., Bourke, E., Alexander, D., Warr, M. R., Barry-Holson, K., Le Beau, M. M., Morrison, C. G., & Passegué, E. (2010) · Cell Stem Cell
DNA Repair MechanismsHematopoietic Stem Cell Transplantation
Cited by 599
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Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review
Duda-Chodak, A., Tarko, T., Satora, P., & Sroka, P. (2015) · European Journal of Nutrition
Gut microbiota and healthPhytochemicals and Antioxidant Activities
Cited by 599
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Biology of the RANKL–RANK–OPG System in Immunity, Bone, and Beyond
Walsh, M. C., & Choi, Y. (2014) · Frontiers in Immunology
Bone Metabolism and DiseasesNF-κB Signaling Pathways
Cited by 599
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Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli
Renthal, W., Maze, I., Krishnan, V., Covington, H. E., Xiao, G., Kumar, A., Russo, S. J., Graham, A., Tsankova, N., Kippin, T. E., et al. (2007) · Neuron
Histone Deacetylase Inhibitors ResearchNeurotransmitter Receptor Influence on Behavior
Cited by 599
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Association of BRCA1 and BRCA2 Mutations With Survival, Chemotherapy Sensitivity, and Gene Mutator Phenotype in Patients With Ovarian Cancer
Yang, D., Khan, S., Sun, Y., Hess, K., Shmulevich, I., Sood, A. K., & Zhang, W. (2011) · JAMA
BRCA gene mutations in cancerOvarian cancer diagnosis and treatment
Cited by 599
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DNA markers reveal the complexity of livestock domestication
Bruford, M. W., Bradley, D. G., & Luikart, G. (2003) · Nature Reviews Genetics
Genetic and phenotypic traits in livestockGenetic diversity and population structure
Cited by 599
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The gut microbiota, obesity and insulin resistance
Shen, J., Obin, M. S., & Zhao, L. (2013) · Molecular Aspects of Medicine
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 599
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Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of Prospective Meta-Analyses of Genome-Wide Association Studies From 5 Cohorts
Psaty, B. M., O'Donnell, C. J., Gudnason, V., Lunetta, K. L., Folsom, A. R., Rotter, J. I., Uitterlinden, A. G., Harris, T. B., Witteman, J. C. M., & Boerwinkle, E. (2009) · Circulation: Cardiovascular Genetics
Genetic Associations and EpidemiologyCardiovascular Health and Risk Factors
Cited by 599
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In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes
Kloosterman, W. P., Wienholds, E., de Bruijn, E., Kauppinen, S., & Plasterk, R. H. A. (2006) · Nature Methods
MicroRNA in disease regulationMolecular Biology Techniques and Applications
Cited by 599
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Targeted protein degradation by PROTACs
Neklesa, T. K., Winkler, J. D., & Crews, C. M. (2017) · Pharmacology & Therapeutics
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 599
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Mitotic Misregulation and Human Aging
Ly, D. H., Lockhart, D. J., Lerner, R. A., & Schultz, P. G. (2000) · Science
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 599
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A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis
Carling, D., Zammit, V. A., & Hardie, D. G. (1987) · FEBS Letters
Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis
Cited by 599
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An interlaboratory comparison of physiological and genetic properties of four Saccharomyces cerevisiae strains
van Dijken, J. P., Bauer, J., Brambilla, L., Duboc, P., Francois, J. M., Gancedo, C., Giuseppin, M. L. F., Heijnen, J. J., Hoare, M., Lange, H. C., et al. (2000) · Enzyme and Microbial Technology
Fungal and yeast genetics researchMicrobial Metabolic Engineering and Bioproduction
Cited by 598
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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
Hildebrand, J. M., Tanzer, M. C., Lucet, I. S., Young, S. N., Spall, S. K., Sharma, P., Pierotti, C., Garnier, J.-M., Dobson, R. C. J., Webb, A. I., et al. (2014) · Proceedings of the National Academy of Sciences
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 598
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Most Rare Missense Alleles Are Deleterious in Humans: Implications for Complex Disease and Association Studies
Kryukov, G. V., Pennacchio, L. A., & Sunyaev, S. R. (2007) · The American Journal of Human Genetics
Evolution and Genetic DynamicsGenomics and Rare Diseases
Cited by 598
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Postmitotic neurons develop a p21‐dependent senescence‐like phenotype driven by a DNA damage response
Jurk, D., Wang, C., Miwa, S., Maddick, M., Korolchuk, V., Tsolou, A., Gonos, E. S., Thrasivoulou, C., Jill Saffrey, M., Cameron, K., et al. (2012) · Aging Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 598
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Systematic identification of genetic influences on methylation across the human life course
Gaunt, T. R., Shihab, H. A., Hemani, G., Min, J. L., Woodward, G., Lyttleton, O., Zheng, J., Duggirala, A., McArdle, W. L., Ho, K., et al. (2016) · Genome Biology
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 598
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