Most cited biochemistry, genetics and molecular biology papers
- Verified
The PYRIN-CARD Protein ASC Is an Activating Adaptor for Caspase-1
Srinivasula, S. M., Poyet, J.-L., Razmara, M., Datta, P., Zhang, Z., & Alnemri, E. S. (2002) · Journal of Biological Chemistry
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 573
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Impact of Diet-Modulated Butyrate Production on Intestinal Barrier Function and Inflammation
Bach Knudsen, K. E., Lærke, H. N., Hedemann, M. S., Nielsen, T. S., Ingerslev, A. K., Gundelund Nielsen, D. S., Theil, P. K., Purup, S., Hald, S., Schioldan, A. G., et al. (2018) · Nutrients
Gut microbiota and healthMicrobial Metabolites in Food Biotechnology
Cited by 572
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Actin Assembly and Endocytosis: From Yeast to Mammals
Engqvist-Goldstein, Å. E. Y., & Drubin, D. G. (2003) · Annual Review of Cell and Developmental Biology
Cellular transport and secretionCellular Mechanics and Interactions
Cited by 572
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T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
Desdín-Micó, G., Soto-Heredero, G., Aranda, J. F., Oller, J., Carrasco, E., Gabandé-Rodríguez, E., Blanco, E. M., Alfranca, A., Cussó, L., Desco, M., et al. (2020) · Science
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 572
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Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort
Perna, L., Zhang, Y., Mons, U., Holleczek, B., Saum, K.-U., & Brenner, H. (2016) · Clinical Epigenetics
Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence
Cited by 572
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Force production by single kinesin motors
Schnitzer, M. J., Visscher, K., & Block, S. M. (2000) · Nature Cell Biology
Microtubule and mitosis dynamicsForce Microscopy Techniques and Applications
Cited by 572
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Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis
Williams, N. M., Zaharieva, I., Martin, A., Langley, K., Mantripragada, K., Fossdal, R., Stefansson, H., Stefansson, K., Magnusson, P., Gudmundsson, O. O., et al. (2010) · The Lancet
Genomic variations and chromosomal abnormalitiesAttention Deficit Hyperactivity Disorder
Cited by 572
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An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells
Yeo, G. W., Coufal, N. G., Liang, T. Y., Peng, G. E., Fu, X.-D., & Gage, F. H. (2009) · Nature Structural & Molecular Biology
RNA Research and SplicingRNA regulation and disease
Cited by 572
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Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis
Yoshida, M., Minagawa, S., Araya, J., Sakamoto, T., Hara, H., Tsubouchi, K., Hosaka, Y., Ichikawa, A., Saito, N., Kadota, T., et al. (2019) · Nature Communications
Ferroptosis and cancer prognosisChronic Obstructive Pulmonary Disease (COPD) Research
Cited by 572
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Partial uracil–DNA–glycosylase treatment for screening of ancient DNA
Rohland, N., Harney, E., Mallick, S., Nordenfelt, S., & Reich, D. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences
Forensic and Genetic ResearchGenomics and Phylogenetic Studies
Cited by 572
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Transposable elements in cancer
Burns, K. H. (2017) · Nature Reviews Cancer
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 572
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Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans
Hagan, T., Cortese, M., Rouphael, N., Boudreau, C., Linde, C., Maddur, M. S., Das, J., Wang, H., Guthmiller, J., Zheng, N.-Y., et al. (2019) · Cell
Gut microbiota and healthImmune responses and vaccinations
Cited by 572
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A Core Human Microbiome as Viewed through 16S rRNA Sequence Clusters
Huse, S. M., Ye, Y., Zhou, Y., & Fodor, A. A. (2012) · PLoS ONE
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 572
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Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase
Santos, C. X. C., Tanaka, L. Y., Wosniak, J., & Laurindo, F. R. M. (2009) · Antioxidants & Redox Signaling
Endoplasmic Reticulum Stress and DiseaseRedox biology and oxidative stress
Cited by 572
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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival
Rathmell, J. C., Fox, C. J., Plas, D. R., Hammerman, P. S., Cinalli, R. M., & Thompson, C. B. (2003) · Molecular and Cellular Biology
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 572
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An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
Sayed, N., Huang, Y., Nguyen, K., Krejciova-Rajaniemi, Z., Grawe, A. P., Gao, T., Tibshirani, R., Hastie, T., Alpert, A., Cui, L., et al. (2021) · Nature Aging
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 572
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Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids
Heyes, J., Palmer, L., Bremner, K., & MacLachlan, I. (2005) · Journal of Controlled Release
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 572
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Microfluidic isolation and transcriptome analysis of serum microvesicles
Chen, C., Skog, J., Hsu, C.-H., Lessard, R. T., Balaj, L., Wurdinger, T., Carter, B. S., Breakefield, X. O., Toner, M., & Irimia, D. (2010) · Lab Chip
Extracellular vesicles in diseaseMicrofluidic and Bio-sensing Technologies
Cited by 572
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A newly identified N‐terminal amino acid sequence of human eIF4G binds poly(A)‐binding protein and functions in poly(A)‐dependent translation
Imataka, H., Gradi, A., & Sonenberg, N. (1998) · The EMBO Journal
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 572
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Laboratory mice born to wild mice have natural microbiota and model human immune responses
Rosshart, S. P., Herz, J., Vassallo, B. G., Hunter, A., Wall, M. K., Badger, J. H., McCulloch, J. A., Anastasakis, D. G., Sarshad, A. A., Leonardi, I., et al. (2019) · Science
Gut microbiota and healthAnimal Genetics and Reproduction
Cited by 572
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NMD: a multifaceted response to premature translational termination
Kervestin, S., & Jacobson, A. (2012) · Nature Reviews Molecular Cell Biology
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 572
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The IκB kinase complex in NF‐κB regulation and beyond
Hinz, M., & Scheidereit, C. (2014) · The EMBO Reports
NF-κB Signaling PathwaysSignaling Pathways in Disease
Cited by 572
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Association of FOXO3A variation with human longevity confirmed in German centenarians
Flachsbart, F., Caliebe, A., Kleindorp, R., Blanché, H., von Eller-Eberstein, H., Nikolaus, S., Schreiber, S., & Nebel, A. (2009) · Proceedings of the National Academy of Sciences
FOXO transcription factor regulationGenetics, Aging, and Longevity in Model Organisms
Cited by 572
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Biomarkers of response and resistance to antiangiogenic therapy
Jain, R. K., Duda, D. G., Willett, C. G., Sahani, D. V., Zhu, A. X., Loeffler, J. S., Batchelor, T. T., & Sorensen, A. G. (2009) · Nature Reviews Clinical Oncology
Angiogenesis and VEGF in CancerColorectal Cancer Treatments and Studies
Cited by 572
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