Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase.

Metzger, D., Clifford, J., Chiba, H., & Chambon, P. (1995) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 570

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

Lee, J. H., Budanov, A. V., Park, E. J., Birse, R., Kim, T. E., Perkins, G. A., Ocorr, K., Ellisman, M. H., Bodmer, R., Bier, E., et al. (2010) · Science

Genetics, Aging, and Longevity in Model OrganismsPI3K/AKT/mTOR signaling in cancer

Cited by 570

Somatic mutation in single human neurons tracks developmental and transcriptional history

Lodato, M. A., Woodworth, M. B., Lee, S., Evrony, G. D., Mehta, B. K., Karger, A., Lee, S., Chittenden, T. W., D’Gama, A. M., Cai, X., et al. (2015) · Science

Single-cell and spatial transcriptomicsCancer Genomics and Diagnostics

Cited by 570

Single Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation

Kolodziejczyk, A. A., Kim, J. K., Tsang, J. C. H., Ilicic, T., Henriksson, J., Natarajan, K. N., Tuck, A. C., Gao, X., Bühler, M., Liu, P., et al. (2015) · Cell Stem Cell

Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics

Cited by 570

A public genome-scale lentiviral expression library of human ORFs

Yang, X., Boehm, J. S., Yang, X., Salehi-Ashtiani, K., Hao, T., Shen, Y., Lubonja, R., Thomas, S. R., Alkan, O., Bhimdi, T., et al. (2011) · Nature Methods

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 570

The Gut Microbiome Profile in Obesity: A Systematic Review

Castaner, O., Goday, A., Park, Y.-M., Lee, S.-H., Magkos, F., Shiow, S.-A. T. E., & Schröder, H. (2018) · International Journal of Endocrinology

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 570

Experimental evolution of multicellularity

Ratcliff, W. C., Denison, R. F., Borrello, M., & Travisano, M. (2012) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsEvolutionary Game Theory and Cooperation

Cited by 570

Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus

Shenouda, S. M., Widlansky, M. E., Chen, K., Xu, G., Holbrook, M., Tabit, C. E., Hamburg, N. M., Frame, A. A., Caiano, T. L., Kluge, M. A., et al. (2011) · Circulation

Mitochondrial Function and PathologyNitric Oxide and Endothelin Effects

Cited by 570

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

Losman, J.-A., & Kaelin, W. G. (2013) · Genes & Development

Cancer, Hypoxia, and MetabolismGlioma Diagnosis and Treatment

Cited by 570

Id proteins in development, cell cycle and cancer

Ruzinova, M. B., & Benezra, R. (2003) · Trends in Cell Biology

Developmental Biology and Gene RegulationTGF-β signaling in diseases

Cited by 570

Regulation of NFATc1 in Osteoclast Differentiation

Kim, J. H., & Kim, N. (2014) · Journal of Bone Metabolism

Bone Metabolism and DiseasesSignaling Pathways in Disease

Cited by 570

Circulating Glycotoxins and Dietary Advanced Glycation Endproducts: Two Links to Inflammatory Response, Oxidative Stress, and Aging

Uribarri, J., Cai, W., Peppa, M., Goodman, S., Ferrucci, L., Striker, G., & Vlassara, H. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Advanced Glycation End Products researchPotato Plant Research

Cited by 570

Measuring biological age using omics data

Rutledge, J., Oh, H., & Wyss-Coray, T. (2022) · Nature Reviews Genetics

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 570

Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity

Xirodimas, D. P., Saville, M. K., Bourdon, J.-C., Hay, R. T., & Lane, D. P. (2004) · Cell

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 570

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Walther, D. M., Kasturi, P., Zheng, M., Pinkert, S., Vecchi, G., Ciryam, P., Morimoto, R. I., Dobson, C. M., Vendruscolo, M., Mann, M., et al. (2015) · Cell

Genetics, Aging, and Longevity in Model OrganismsHeat shock proteins research

Cited by 569

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Chan-Penebre, E., Kuplast, K. G., Majer, C. R., Boriack-Sjodin, P. A., Wigle, T. J., Johnston, L. D., Rioux, N., Munchhof, M. J., Jin, L., Jacques, S. L., et al. (2015) · Nature Chemical Biology

Cancer-related gene regulationProtein Degradation and Inhibitors

Cited by 569

Eighteen‐year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: The National Cancer Institute randomized trial

Poggi, M. M., Danforth, D. N., Sciuto, L. C., Smith, S. L., Steinberg, S. M., Liewehr, D. J., Menard, C., Lippman, M. E., Lichter, A. S., & Altemus, R. M. (2003) · Cancer

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 569

Suppression of tumor growth and metastasis in Mgat5-deficient mice

Granovsky, M., Fata, J., Pawling, J., Muller, W. J., Khokha, R., & Dennis, J. W. (2000) · Nature Medicine

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 569

Extracellular vesicles in physiological and pathological conditions

Yuana, Y., Sturk, A., & Nieuwland, R. (2013) · Blood Reviews

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 569

Microbial regulation of organismal energy homeostasis

Cani, P. D., Van Hul, M., Lefort, C., Depommier, C., Rastelli, M., & Everard, A. (2019) · Nature Metabolism

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 569

Predictable and precise template-free CRISPR editing of pathogenic variants

Shen, M. W., Arbab, M., Hsu, J. Y., Worstell, D., Culbertson, S. J., Krabbe, O., Cassa, C. A., Liu, D. R., Gifford, D. K., & Sherwood, R. I. (2018) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 569

Proteasome Inhibition As a Novel Therapeutic Target in Human Cancer

Rajkumar, S. V., Richardson, P. G., Hideshima, T., & Anderson, K. C. (2005) · Journal of Clinical Oncology

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 569

Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates

Burgess, S., & Labrecque, J. A. (2018) · European Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 569

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

Gabel, H. W., Kinde, B., Stroud, H., Gilbert, C. S., Harmin, D. A., Kastan, N. R., Hemberg, M., Ebert, D. H., & Greenberg, M. E. (2015) · Nature

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 569