Most cited biochemistry, genetics and molecular biology papers
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Structure-function relationships in the sodium-potassium ATPase .alpha. subunit: site-directed mutagenesis of glutamine-111 to arginine and asparagine-122 to aspartic acid generates a ouabain-resistant enzyme
Price, E. M., & Lingrel, J. B. (1988) · Biochemistry
Ion Transport and Channel RegulationATP Synthase and ATPases Research
Cited by 410
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Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
Xia, X., Lemieux, M. E., Li, W., Carroll, J. S., Brown, M., Liu, X. S., & Kung, A. L. (2009) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismGenomics and Chromatin Dynamics
Cited by 410
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Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
Korolchuk, V. I., Miwa, S., Carroll, B., & von Zglinicki, T. (2017) · EBioMedicine
Autophagy in Disease and TherapyTelomeres, Telomerase, and Senescence
Cited by 409
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Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution
Sollars, V., Lu, X., Xiao, L., Wang, X., Garfinkel, M. D., & Ruden, D. M. (2003) · Nature Genetics
Heat shock proteins researchEvolution and Genetic Dynamics
Cited by 409
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Modulation of the human gut microbiota by dietary fibres occurs at the species level
Chung, W. S. F., Walker, A. W., Louis, P., Parkhill, J., Vermeiren, J., Bosscher, D., Duncan, S. H., & Flint, H. J. (2016) · BMC Biology
Gut microbiota and healthMicrobial Metabolites in Food Biotechnology
Cited by 409
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Focal adhesions, stress fibers and mechanical tension
Burridge, K., & Guilluy, C. (2016) · Experimental Cell Research
Cellular Mechanics and InteractionsSkin and Cellular Biology Research
Cited by 409
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Apolipoprotein E binding drives structural and compositional rearrangement of mRNA-containing lipid nanoparticles
Sebastiani, F., Yanez Arteta, M., Lerche, M., Porcar, L., Lang, C., Bragg, R. A., Elmore, C. S., Krishnamurthy, V. R., Russell, R. A., Darwish, T., et al. (2021) · ACS Nano
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 409
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Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.
Martin, D. I., & Orkin, S. H. (1990) · Genes & Development
Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders
Cited by 409
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Modular networks and cumulative impact of lateral transfer in prokaryote genome evolution
Dagan, T., Artzy-Randrup, Y., & Martin, W. (2008) · Proceedings of the National Academy of Sciences
Genomics and Phylogenetic StudiesBacterial Genetics and Biotechnology
Cited by 409
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Artemisia annua L. (Asteraceae) trichome‐specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin
Teoh, K. H., Polichuk, D. R., Reed, D. W., Nowak, G., & Covello, P. S. (2006) · FEBS Letters
Plant biochemistry and biosynthesisSesquiterpenes and Asteraceae Studies
Cited by 409
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COP9 Signalosome
Cope, G. A., & Deshaies, R. J. (2003) · Cell
Ubiquitin and proteasome pathwaysMicrotubule and mitosis dynamics
Cited by 409
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Advances in Targeting ‘Undruggable’ transcription Factors With Small Molecules
Henley, M. J., & Koehler, A. N. (2021) · Nature Reviews Drug Discovery
Protein Degradation and InhibitorsComputational Drug Discovery Methods
Cited by 409
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ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma
Sanz-Moreno, V., Gaggioli, C., Yeo, M., Albrengues, J., Wallberg, F., Viros, A., Hooper, S., Mitter, R., Féral, C. C., Cook, M., et al. (2011) · Cancer Cell
Cellular Mechanics and InteractionsCytokine Signaling Pathways and Interactions
Cited by 409
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Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21
Inagaki, T., Lin, V. Y., Goetz, R., Mohammadi, M., Mangelsdorf, D. J., & Kliewer, S. A. (2008) · Cell Metabolism
Fibroblast Growth Factor ResearchGrowth Hormone and Insulin-like Growth Factors
Cited by 409
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To milliseconds and beyond: challenges in the simulation of protein folding
Lane, T. J., Shukla, D., Beauchamp, K. A., & Pande, V. S. (2013) · Current Opinion in Structural Biology
Protein Structure and DynamicsRNA and protein synthesis mechanisms
Cited by 409
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Nanoscopic structure of DNA condensed for gene delivery
Dunlap, D. (1997) · Nucleic Acids Research
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 409
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Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm-aging”
Pinti, M., Cevenini, E., Nasi, M., De Biasi, S., Salvioli, S., Monti, D., Benatti, S., Gibellini, L., Cotichini, R., Stazi, M. A., et al. (2014) · European Journal of Immunology
Mitochondrial Function and PathologyImmune Response and Inflammation
Cited by 409
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Integrating environmental covariates and crop modeling into the genomic selection framework to predict genotype by environment interactions
Heslot, N., Akdemir, D., Sorrells, M. E., & Jannink, J.-L. (2014) · Theoretical and Applied Genetics
Genetic and phenotypic traits in livestockGenetics and Plant Breeding
Cited by 409
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Metagenome-wide association of gut microbiome features for schizophrenia
Zhu, F., Ju, Y., Wang, W., Wang, Q., Guo, R., Ma, Q., Sun, Q., Fan, Y., Xie, Y., Yang, Z., et al. (2020) · Nature Communications
Gut microbiota and healthSchizophrenia research and treatment
Cited by 409
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microRNA miR-27b impairs human adipocyte differentiation and targets PPARγ
Karbiener, M., Fischer, C., Nowitsch, S., Opriessnig, P., Papak, C., Ailhaud, G., Dani, C., Amri, E.-Z., & Scheideler, M. (2009) · Biochemical and Biophysical Research Communications
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 409
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Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope
Kent, S. C., Chen, Y., Bregoli, L., Clemmings, S. M., Kenyon, N. S., Ricordi, C., Hering, B. J., & Hafler, D. A. (2005) · Nature
Diabetes and associated disordersT-cell and B-cell Immunology
Cited by 409
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Advances in the production of human therapeutic proteins in yeasts and filamentous fungi
Gerngross, T. U. (2004) · Nature Biotechnology
Fungal and yeast genetics researchViral Infectious Diseases and Gene Expression in Insects
Cited by 409
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Gut microbiota in multiple sclerosis: possible influence of immunomodulators
Cantarel, B. L., Waubant, E., Chehoud, C., Kuczynski, J., DeSantis, T. Z., Warrington, J., Venkatesan, A., Fraser, C. M., & Mowry, E. M. (2015) · Journal of Investigative Medicine
Gut microbiota and healthMultiple Sclerosis Research Studies
Cited by 409
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USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma
Eichhorn, P. J. A., Rodón, L., Gonzàlez-Juncà, A., Dirac, A., Gili, M., Martínez-Sáez, E., Aura, C., Barba, I., Peg, V., Prat, A., et al. (2012) · Nature Medicine
TGF-β signaling in diseasesUbiquitin and proteasome pathways
Cited by 409
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