COP9 Signalosome

Auxin regulates SCFTIR1-dependent degradation of AUX/IAA proteins

Gray, W. M., Kepinski, S., Rouse, D. T., Leyser, O., & Estelle, M. A. (2001) · Nature · doi:10.1038/35104500 · Cited by 1,415 · see citing works

Targeted destabilization of HY5 during light-regulated development of Arabidopsis

Østerlund, M. T., Hardtke, C. S., Wei, N., & Deng, X. W. (2000) · Nature · doi:10.1038/35013076 · Cited by 1,363 · see citing works

SCF and Cullin/RING H2-Based Ubiquitin Ligases

Deshaies, R. J. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.435 · Cited by 1,238 · see citing works

The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage

Groisman, R., Polanowska, J., Kuraoka, I., Sawada, J.-I., Saijo, M., Drapkin, R., Kisselev, A. F., Tanaka, K., & Nakatani, Y. (2003) · Cell · doi:10.1016/s0092-8674(03)00316-7 · Cited by 739 · see citing works

Promotion of NEDD8-CUL1 Conjugate Cleavage by COP9 Signalosome

Lyapina, S., Cope, G. A., Shevchenko, A., Serino, G., Tsuge, T., Zhou, C., Wolf, D. A., Wei, N., Shevchenko, A., & Deshaies, R. J. (2001) · Science · doi:10.1126/science.1059780 · Cited by 699 · see citing works

Role of Predicted Metalloprotease Motif of Jab1/Csn5 in Cleavage of Nedd8 from Cul1

Cope, G. A., Suh, G. S. B., Aravind, L., Schwarz, S. E., Zipursky, S. L., Koonin, E. V., & Deshaies, R. J. (2002) · Science · doi:10.1126/science.1075901 · Cited by 682 · see citing works

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

Tomoda, K., Kubota, Y., & Kato, J. (1999) · Nature · doi:10.1038/18230 · Cited by 632 · see citing works

Structure of a β-TrCP1-Skp1-β-Catenin Complex

Wu, G., Xu, G., Schulman, B. A., Jeffrey, P. D., Harper, J. W., & Pavletich, N. P. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00234-x · Cited by 612 · see citing works

The RAR1 Interactor SGT1, an Essential Component of R Gene-Triggered Disease Resistance

Azevedo, C., Sadanandom, A., Kitagawa, K., Freialdenhoven, A., Shirasu, K., & Schulze‐Lefert, P. (2002) · Science · doi:10.1126/science.1067554 · Cited by 611 · see citing works

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

Kleemann, R., Haußer, A., Geiger, G., Mischke, R., Burger‐Kentischer, A., Flieger, O., Johannes, F., Roger, T., Calandra, T., Kapurniotu, A., et al. (2000) · Nature · doi:10.1038/35041591 · Cited by 567 · see citing works

Direct Interaction of Arabidopsis Cryptochromes with COP1 in Light Control Development

Wang, H., Ma, L., Li, J.-M., Zhao, H., & Deng, X. W. (2001) · Science · doi:10.1126/science.1063630 · Cited by 525 · see citing works

Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thalianaPreprint

Gray, W. M., del Pozo, J. C., Walker, L., Hobbie, L. J., Risseeuw, E. P., Banks, T. W., Crosby, W. L., Yang, M., Mā, H., & Estelle, M. A. (1999) · Genes & Development · doi:10.1101/gad.13.13.1678 · Cited by 525 · see citing works

Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCF TIR1 in Mediating Auxin Response

Schwechheimer, C., Serino, G., Callis, J., Crosby, W. L., Lyapina, S., Deshaies, R. J., Gray, W. M., Estelle, M. A., & Deng, X. (2001) · Science · doi:10.1126/science.1059776 · Cited by 475 · see citing works

A new group of conserved coactivators that increase the specificity of AP-1 transcription factors

Claret, F.-X., Hibi, M., Dhut, S., Toda, T., & Karin, M. (1996) · Nature · doi:10.1038/383453a0 · Cited by 466 · see citing works

Nedd8 Modification of Cul-1 Activates SCF^βTrCP-Dependent Ubiquitination of IκBα

Read, M. A., Brownell, J. E., Gladysheva, T. B., Hottelet, M., Parent, L. A., Coggins, M. B., Pierce, J. W., Podust, V. N., Luo, R.-S., Chau, V., et al. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.7.2326-2333.2000 · Cited by 363 · see citing works

A novel protein modification pathway related to the ubiquitin system

Liakopoulos, D., Doenges, G., Matuschewski, K., & Jentsch, S. (1998) · The EMBO Journal · doi:10.1093/emboj/17.8.2208 · Cited by 361 · see citing works

NEDD8 recruits E2‐ubiquitin to SCF E3 ligase

Kawakami, T., Chiba, T., Suzuki, T., Iwai, K., Yamanaka, K., Minato, N., Suzuki, H., Shimbara, N., Hidaka, Y., Osaka, F., et al. (2001) · EMBO Journal · doi:10.1093/emboj/20.15.4003 · Cited by 344 · see citing works

Prophase Destruction of Emi1 by the SCFβTrCP/Slimb Ubiquitin Ligase Activates the Anaphase Promoting Complex to Allow Progression beyond Prometaphase

Margottin-Goguet, F., Hsu, J. Y., Loktev, A. V., Hsieh, H.-M., Reimann, J. D. R., & Jackson, P. K. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00153-9 · Cited by 337 · see citing works

STRUCTURE OF A BETA-TRCPI-SKP1-BETA-CATENIN COMPLEX: DESTRUCTION MOTIF BINDING AND LYSINE SPECIFICITY OF THE SCF(BETA-TRCP1) UBIQUITIN LIGASE

Wu, G., Xu, G., Schulman, B. A., Jeffrey, P. D., Harper, J. W., & Pavletich, N. P. (2003) · Molecules and Cells · Cited by 333 · see citing works

NEDD8 Modification of CUL1 Dissociates p120CAND1, an Inhibitor of CUL1-SKP1 Binding and SCF Ligases

Liu, J., Furukawa, M., Matsumoto, T., & Xiong, Y. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00783-9 · Cited by 319 · see citing works

Modification of yeast Cdc53p by the ubiquitin-related protein Rub1p affects function of the SCFCdc4 complexPreprint

Lammer, D., Mathias, N., Laplaza, J. M., Jiang, W., Liu, Y., Callis, J., Goebl, M. G., & Estelle, M. A. (1998) · Genes & Development · doi:10.1101/gad.12.7.914 · Cited by 312 · see citing works

CAND1 Binds to Unneddylated CUL1 and Regulates the Formation of SCF Ubiquitin E3 Ligase Complex

Zheng, J., Yang, X., Harrell, J. M., Ryzhikov, S., Shim, E., Lykke‐Hartmann, K., Wei, N., Sun, H., Kobayashi, R., & Zhang, H. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00784-0 · Cited by 309 · see citing works

The Cytoplasmic Shuttling and Subsequent Degradation of p27Kip1 Mediated by Jab1/CSN5 and the COP9 Signalosome Complex

Tomoda, K., Kubota, Y., Arata, Y., Mori, S., Maeda, M., Tanaka, T., Yoshida, M., Yoneda‐Kato, N., & Kato, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m104431200 · Cited by 307 · see citing works

Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism

Galan, J., & Peter, M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.9124 · Cited by 269 · see citing works

Ubiquitination and Degradation of the Substrate Recognition Subunits of SCF Ubiquitin–Protein Ligases

Zhou, P., & Howley, P. M. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80156-2 · Cited by 259 · see citing works

A Nedd8 conjugation pathway is essential for proteolytic targeting of p27 Kip1 by ubiquitination

Podust, V. N., Brownell, J. E., Gladysheva, T. B., Luo, R.-S., Wang, C., Coggins, M. B., Pierce, J. W., Lightcap, E. S., & Chau, V. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.090465597 · Cited by 244 · see citing works

Making sense of the COP9 signalosome: a regulatory protein complex conserved from Arabidopsis to human

Wei, N., & Deng, X. W. (1999) · Trends in Genetics · doi:10.1016/s0168-9525(98)01670-9 · Cited by 234 · see citing works

COP9 signalosome revisited: a novel mediator of protein degradation

Schwechheimer, C., & Deng, X. (2001) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02091-8 · Cited by 217 · see citing works

The COP9 Signalosome Interacts Physically with SCFCOI1 and Modulates Jasmonate Responses

Feng, S., Ma, L., Wang, X., Xie, D., Dinesh-Kumar, S. P., Wei, N., & Deng, X. W. (2003) · The Plant Cell · doi:10.1105/tpc.010207 · Cited by 208 · see citing works

Conjugation of Nedd8 to CUL1 Enhances the Ability of the ROC1-CUL1 Complex to Promote Ubiquitin Polymerization

Wu, K. K.-Y., Chen, A., & Pan, Z. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004847200 · Cited by 204 · see citing works

Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

Uhle, S., Medalia, O., Waldron, R. T., Dumdey, R., Henklein, P., Bech‐Otschir, D., Huang, X., Berse, M., Sperling, J. M., Schade, R., et al. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg127 · Cited by 202 · see citing works

Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanismsPreprint

Liu, C., Powell, K. A., Mundt, K., Wu, L., Carr, A. M., & Caspari, T. (2003) · Genes & Development · doi:10.1101/gad.1090803 · Cited by 191 · see citing works

Fission Yeast COP9/Signalosome Suppresses Cullin Activity through Recruitment of the Deubiquitylating Enzyme Ubp12p

Zhou, C., Wee, S., Rhee, E., Naumann, M., Dubiel, W., & Wolf, D. A. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00136-9 · Cited by 180 · see citing works

Tome-1, a Trigger of Mitotic Entry, Is Degraded during G1 via the APC

Ayad, N. G., Rankin, S., Murakami, M. S., Jebanathirajah, J. A., Gygi, S. P., & Kirschner, M. W. (2003) · Cell · doi:10.1016/s0092-8674(03)00232-0 · Cited by 179 · see citing works

Neddylation and Deneddylation of CUL-3 Is Required to Target MEI-1/Katanin for Degradation at the Meiosis-to-Mitosis Transition in C. elegans

Pintard, L., Kurz, T., Luke-Glaser, S., Willis, J. H., Peter, M., & Bowerman, B. A. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00336-1 · Cited by 178 · see citing works

The COP9 Signalosome Inhibits p27kip1 Degradation and Impedes G1-S Phase Progression via Deneddylation of SCF Cul1

Yang, X., Menon, S., Lykke‐Hartmann, K., Tsuge, T., Xiao, D., Wang, X., Rodriguez-Suarez, R. J., Zhang, H., & Wei, N. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00791-1 · Cited by 171 · see citing works

The COP9 Signalosome Interacts with SCFUFO and Participates in Arabidopsis Flower Development

Wang, X., Feng, S., Nakayama, N., Crosby, W. L., Irish, V. F., Deng, X. W., & Wei, N. (2003) · The Plant Cell · doi:10.1105/tpc.009936 · Cited by 158 · see citing works

The COP9/signalosome complex is conserved in fission yeast and has a role in S phase

Mundt, K., Porte, J., Murray, J. M., Brikos, C., Christensen, P. U., Caspari, T., Hagan, I., Millar, J. B. A., Simanis, V., Hofmann, K., et al. (1999) · Current Biology · doi:10.1016/s0960-9822(00)80091-3 · Cited by 157 · see citing works

Context of Multiubiquitin Chain Attachment Influences the Rate of Sic1 Degradation

Petroski, M. D., & Deshaies, R. J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00221-1 · Cited by 149 · see citing works

The role of COP1 in repression of Arabidopsis photomorphogenic development

Østerlund, M. T., Ang, L., & Deng, X. W. (1999) · Trends in Cell Biology · doi:10.1016/s0962-8924(99)01499-3 · Cited by 147 · see citing works

COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways inDrosophila melanogaster

Oron, E., Mannervik, M., Rencus‐Lazar, S., Harari‐Steinberg, O., Neuman-Silberberg, S., Segal, D., & Chamovitz, D. (2002) · Development · doi:10.1242/dev.129.19.4399 · Cited by 132 · see citing works

The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis

Doronkin, S., Djagaeva, I., & Beckendorf, S. K. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00121-7 · Cited by 121 · see citing works

Pseudosubstrate regulation of the SCF β-TrCP ubiquitin ligase by hnRNP-UPreprint

Davis, M., Hatzubai, A., Andersen, J., Ben-Shushan, E., Fisher, G. Z., Yaron, A., Bauskin, A. R., Mercurio, F., Mann, M., & Ben‐Neriah, Y. (2002) · Genes & Development · doi:10.1101/gad.218702 · Cited by 119 · see citing works

Deletion Mutants in COP9/Signalosome Subunits in Fission YeastSchizosaccharomyces pombeDisplay Distinct Phenotypes

Mundt, K., Liu, C., & Carr, A. M. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-10-0521 · Cited by 118 · see citing works

Inositol 1,3,4-Trisphosphate 5/6-Kinase Associates with the COP9 Signalosome by Binding to CSN1

Sun, Y. J., Wilson, M. P., & Majerus, P. W. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m208709200 · Cited by 100 · see citing works

Drosophila JAB1/CSN5 Acts in Photoreceptor Cells to Induce Glial Cells

Suh, G. S. B., Poeck, B., Chouard, T., Oron, E., Segal, D., Chamovitz, D., & Zipursky, S. L. (2002) · Neuron · doi:10.1016/s0896-6273(01)00576-1 · Cited by 94 · see citing works

Release of Ubiquitin-Charged Cdc34-S∼Ub from the RING Domain Is Essential for Ubiquitination of the SCFCdc4-Bound Substrate Sic1

Deffenbaugh, A. E., Scaglione, K. M., Zhang, L., Moore, J. M., Buranda, T., Sklar, L. A., & Skowyra, D. (2003) · Cell · doi:10.1016/s0092-8674(03)00641-x · Cited by 79 · see citing works

Inositol 1,3,4-Trisphosphate 5/6-Kinase Is a Protein Kinase That Phosphorylates the Transcription Factors c-Jun and ATF-2

Wilson, M. P., Sun, Y., Cao, L., & Majerus, P. W. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106605200 · Cited by 78 · see citing works

Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo

Peng, Z., Shen, Y., Feng, S., Wang, X., Chitteti, B. N., Vierstra, R. D., & Deng, X. W. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00439-1 · Cited by 77 · see citing works

Conservation of the COP9/signalosome in budding yeast.

Wee, S., Hetfeld, B. K. J., Dubiel, W., & Wolf, D. A. (2002) · BMC Genetics · doi:10.1186/1471-2156-3-15 · Cited by 74 · see citing works

TIP120A Associates with Cullins and Modulates Ubiquitin Ligase Activity

Min, K.-W., Hwang, J., Lee, J., Park, Y., Tamura, T.-A., & Yoon, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m213070200 · Cited by 72 · see citing works

The GLH Proteins, Caenorhabditis elegans P Granule Components, Associate with CSN-5 and KGB-1, Proteins Necessary for Fertility, and with ZYX-1, a Predicted Cytoskeletal Protein

Smith, P. A., Leung-Chiu, W. M. A., Montgomery, R., Orsborn, A. M., Kuznicki, K., Gressman-Coberly, E., Mutapčić, L., & Bennett, K. L. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0832 · Cited by 64 · see citing works

Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1

Oshikawa, K., Matsumoto, M., Yada, M., Kamura, T., Hatakeyama, S., & Nakayama, K. I. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00501-1 · Cited by 63 · see citing works

The COP9 signalosome-like complex in S. cerevisiae and links to other PCI complexes

Maytal‐Kivity, V., Pick, E., Piran, R., Hofmann, K., & Glickman, M. H. (2003) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(02)00378-3 · Cited by 60 · see citing works

CSN5/Jab1mutations affect axis formation in theDrosophilaoocyte by activating a meiotic checkpoint

Doronkin, S., Djagaeva, I., & Beckendorf, S. K. (2002) · Development · doi:10.1242/dev.129.21.5053 · Cited by 59 · see citing works

TIP120A associates with unneddylated cullin 1 and regulates its neddylation

Hwang, J., Min, K.-W., Tamura, T.-A., & Yoon, J. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00321-1 · Cited by 35 · see citing works

JAB1/CSN5 interacts with the GAL4 DNA binding domain: A note of caution about two-hybrid interactions

Nordgård, O., Dahle, Ø., Andersen, T. Ø., & Gabrielsen, O. S. (2001) · Biochimie · doi:10.1016/s0300-9084(01)01329-3 · Cited by 30 · see citing works

COP1 patrols the night beat

Deshaies, R. J., & Meyerowitz, E. M. (2000) · Nature Cell Biology · doi:10.1038/35014095 · Cited by 11 · see citing works

RING Domain E3 Ubiquitin Ligases

Deshaies, R. J., & Joazeiro, C. A. P. (2009) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.78.101807.093809 · Cited by 2,679 · see citing works

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Kobayashi, A., Kang, M.-I., Okawa, H., Ohtsuji, M., Zenke, Y., Chiba, T., Igarashi, K., & Yamamoto, M. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.16.7130-7139.2004 · Cited by 2,224 · see citing works

Function and regulation of cullin–RING ubiquitin ligases

Petroski, M. D., & Deshaies, R. J. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1547 · Cited by 2,148 · see citing works

Defining the Human Deubiquitinating Enzyme Interaction Landscape

Sowa, M. E., Bennett, E. J., Gygi, S. P., & Harper, J. W. (2009) · Cell · doi:10.1016/j.cell.2009.04.042 · Cited by 1,512 · see citing works

Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex

Zhang, D. D., Lo, S., Cross, J. V., Templeton, D. J., & Hannink, M. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.24.10941-10953.2004 · Cited by 1,262 · see citing works

The SCF ubiquitin ligase: insights into a molecular machine

Cardozo, T., & Pagano, M. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1471 · Cited by 1,114 · see citing works

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

Luo, J., Emanuele, M. J., Li, D., Creighton, C. J., Schlabach, M. R., Westbrook, T. F., Wong, K.-K., & Elledge, S. J. (2009) · Cell · doi:10.1016/j.cell.2009.05.006 · Cited by 1,017 · see citing works

Ubiquitin and ubiquitin-like proteins as multifunctional signals

Welchman, R., Gordon, C., & Mayer, R. (2005) · Nature reviews. Molecular cell biology · doi:10.1038/nrm1700 · Cited by 881 · see citing works

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

Wu, Y., Deng, J., Rychahou, P. G., Qiu, S., Evers, B. M., & Zhou, B. P. (2009) · Cancer Cell · doi:10.1016/j.ccr.2009.03.016 · Cited by 797 · see citing works

Dual roles of Nrf2 in cancer

LAU, A., VILLENEUVE, N., Sun, Z., Wong, P. K., & Zhang, D. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.09.003 · Cited by 645 · see citing works

Drug discovery in the ubiquitin–proteasome system

Nalepa, G., Rolfe, M., & Harper, J. W. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2056 · Cited by 619 · see citing works

The Ubiquitin-Proteasome Pathway and Plant Development

Moon, J., Parry, G., & Estelle, M. A. (2004) · The Plant Cell · doi:10.1105/tpc.104.161220 · Cited by 586 · see citing works

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

Banerjee, A. K., Blanco, M. R., Bruce, E. A., Honson, D. D., Chen, L. M., Chow, A., Bhat, P., Ollikainen, N., Quinodoz, S. A., Loney, C., et al. (2020) · Cell · doi:10.1016/j.cell.2020.10.004 · Cited by 583 · see citing works

Coordination of secondarymetabolism and development in fungi: the velvet familyof regulatory proteins

Bayram, Ö., & Braus, G. H. (2011) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2011.00285.x · Cited by 551 · see citing works

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways

Zhao, C., Denison, C., Huibregtse, J. M., Gygi, S. P., & Krug, R. M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504754102 · Cited by 471 · see citing works

Nedd8 on cullin: building an expressway to protein destruction

Pan, Z., Kentsis, A., Dias, D. C., Yamoah, K., & Wu, K. K.-Y. (2004) · Oncogene · doi:10.1038/sj.onc.1207414 · Cited by 430 · see citing works

Deubiquitylases From Genes to Organism

Clague, M. J., Barsukov, I., Coulson, J. M., Liu, H., Rigden, D. J., & Urbé, S. (2013) · Physiological Reviews · doi:10.1152/physrev.00002.2013 · Cited by 422 · see citing works

Regulation of the Nrf2–Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

Villeneuve, N. F., Lau, A., & Zhang, D. D. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3211 · Cited by 423 · see citing works

Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics

Bennett, E. J., Rush, A. J., Gygi, S. P., & Harper, J. W. (2010) · Cell · doi:10.1016/j.cell.2010.11.017 · Cited by 386 · see citing works

ArabidopsisCONSTANS-LIKE3 Is a Positive Regulator of Red Light Signaling and Root Growth

Datta, S., Hettiarachchi, C. M., Deng, X., & Holm, M. (2005) · The Plant Cell · doi:10.1105/tpc.105.038182 · Cited by 371 · see citing works

AMSH is an endosome-associated ubiquitin isopeptidase

McCullough, J., Clague, M. J., & Urbé, S. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200401141 · Cited by 369 · see citing works

Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase

Wertz, I. E., O’Rourke, K. M., Zhang, Z., Dornan, D., Arnott, D. P., Deshaies, R. J., & Dixit, V. M. (2004) · Science · doi:10.1126/science.1093549 · Cited by 366 · see citing works

Function and regulation of protein neddylation

Rabut, G. E. E., & Peter, M. (2008) · EMBO Reports · doi:10.1038/embor.2008.183 · Cited by 351 · see citing works

Building and remodelling Cullin–RING E3 ubiquitin ligases

Lydeard, J. R., Schulman, B. A., & Harper, J. W. (2013) · The EMBO Reports · doi:10.1038/embor.2013.173 · Cited by 327 · see citing works

The DDB1-CUL4A DDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

Kapetanaki, M. G., Guerrero‐Santoro, J., Bisi, D. C., Hsieh, C. L., Rapić-Otrin, V., & Levine, A. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511160103 · Cited by 323 · see citing works

APC/C and SCF: Controlling Each Other and the Cell Cycle

Vodermaier, H. C. (2004) · Current Biology · doi:10.1016/j.cub.2004.09.020 · Cited by 318 · see citing works

Specific Patterns of Electrophile Adduction Trigger Keap1 Ubiquitination and Nrf2 Activation

Hong, F., Sekhar, K. R., Freeman, M. L., & Liebler, D. C. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503346200 · Cited by 316 · see citing works

Cullin-RING ubiquitin ligases: global regulation and activation cycles

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Ubiquitination of Keap1, a BTB-Kelch Substrate Adaptor Protein for Cul3, Targets Keap1 for Degradation by a Proteasome-independent Pathway

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