Most cited biochemistry, genetics and molecular biology papers
- Verified
LC3-positive structures are prominent in autophagy-deficient cells
Runwal, G., Stamatakou, E., Siddiqi, F. H., Puri, C., Zhu, Y., & Rubinsztein, D. C. (2019) · Scientific Reports
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 413
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Pembrolizumab plus chemotherapy as neoadjuvant treatment of high-risk, early-stage triple-negative breast cancer: results from the phase 1b open-label, multicohort KEYNOTE-173 study
Schmid, P., Salgado, R., Park, Y. H., Muñoz-Couselo, E., Kim, S. B., Sohn, J., Im, S.-A., Foukakis, T., Kuemmel, S., Dent, R., et al. (2020) · Annals of Oncology
Breast Cancer Treatment StudiesCancer Immunotherapy and Biomarkers
Cited by 413
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Telomeres and cell senescence—size matters not
Victorelli, S., & Passos, J. F. (2017) · EBioMedicine
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 413
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Are splicing mutations the most frequent cause of hereditary disease?
López-Bigas, N., Audit, B., Ouzounis, C., Parra, G., & Guigó, R. (2005) · FEBS Letters
RNA Research and SplicingGenomics and Rare Diseases
Cited by 412
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The familial aggregation of common psychiatric and substance use disorders in the national comorbidity survey: A family history study
Kendler, K. S., Davis, C. G., & Kessler, R. C. (1997) · British Journal of Psychiatry
Genetic Associations and EpidemiologyChild and Adolescent Psychosocial and Emotional Development
Cited by 412
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The role of geography in human adaptation
Coop, G., Pickrell, J. K., Novembre, J., Kudaravalli, S., Li, J., Absher, D., Myers, R. M., Cavalli-Sforza, L. L., Feldman, M. W., & Pritchard, J. K. (2009) · PLoS Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 412
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Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation
GTEx Consortium, Gamazon, E. R., Segrè, A. V., van de Bunt, M., Wen, X., Xi, H. S., Hormozdiari, F., Ongen, H., Konkashbaev, A., Derks, E. M., et al. (2018) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 412
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γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
Stucki, M., & Jackson, S. P. (2006) · DNA Repair
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 412
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Regulation of pancreas development by hedgehog signaling
Hebrok, M., Kim, S. K., St-Jacques, B., McMahon, A. P., & Melton, D. A. (2000) · Development
Hedgehog Signaling Pathway StudiesPancreatic function and diabetes
Cited by 412
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Model Selection in Phylogenetics
Sullivan, J., & Joyce, P. (2005) · Annual Review of Ecology, Evolution, and Systematics
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 412
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X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Nury, H., Van Renterghem, C., Weng, Y., Tran, A., Baaden, M., Dufresne, V., Changeux, J.-P., Sonner, J. M., Delarue, M., & Corringer, P.-J. (2011) · Nature
Nicotinic Acetylcholine Receptors StudyAnesthesia and Sedative Agents
Cited by 412
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Insulin glargine use and short-term incidence of malignancies-a population-based follow-up study in Sweden
Jonasson, J. M., Ljung, R., Talbäck, M., Haglund, B., Gudbjörnsdòttir, S., & Steineck, G. (2009) · Diabetologia
Metabolism, Diabetes, and CancerDiabetes Management and Research
Cited by 412
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YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth
Low, B. C., Pan, C. Q., Shivashankar, G. V., Bershadsky, A., Sudol, M., & Sheetz, M. (2014) · FEBS Letters
Hippo pathway signaling and YAP/TAZCellular Mechanics and Interactions
Cited by 412
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μ1A‐adaptin‐deficient mice: lethality, loss of AP‐1 binding and rerouting of mannose 6‐phosphate receptors
Meyer, C., Zizioli, D., Lausmann, S., Eskelinen, E., Hamann, J., Saftig, P., von Figura, K., & Schu, P. (2000) · The EMBO Journal
Cellular transport and secretionAutophagy in Disease and Therapy
Cited by 412
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A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency
Hacein-Bey-Abina, S., Pai, S.-Y., Gaspar, H. B., Armant, M., Berry, C. C., Blanche, S., Bleesing, J., Blondeau, J., de Boer, H., Buckland, K. F., et al. (2014) · New England Journal of Medicine
Virus-based gene therapy researchImmunodeficiency and Autoimmune Disorders
Cited by 412
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What's in a picture? The temptation of image manipulation
Rossner, M., & Yamada, K. M. (2004) · The Journal of Cell Biology
Cell Image Analysis TechniquesPhotography and Visual Culture
Cited by 412
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Osteoporosis, inflammation and ageing
Ginaldi, L., Di Benedetto, M. C., & De Martinis, M. (2005) · Immunity & Ageing
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 412
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Cell segmentation in imaging-based spatial transcriptomics
Petukhov, V., Xu, R. J., Soldatov, R. A., Cadinu, P., Khodosevich, K., Moffitt, J. R., & Kharchenko, P. V. (2022) · Nature Biotechnology
Single-cell and spatial transcriptomicsCell Image Analysis Techniques
Cited by 412
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Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
Tubio, J. M. C., Li, Y., Ju, Y. S., Martincorena, I., Cooke, S. L., Tojo, M., Gundem, G., Pipinikas, C. P., Zamora, J., Raine, K., et al. (2014) · Science
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 412
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Histocompatibility (HL-A) Antigens, Lymphocytotoxic Antibodies and Tissue Antibodies in Patients with Diabetes Mellitus
Singal, D. P., & Blajchman, M. A. (1973) · Diabetes
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 412
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The Role of Skeletal Muscle Glycogen Breakdown for Regulation of Insulin Sensitivity by Exercise
Jensen, J., Rustad, P. I., Kolnes, A. J., & Lai, Y.-C. (2011) · Frontiers in Physiology
Metabolism, Diabetes, and CancerMuscle metabolism and nutrition
Cited by 412
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Alzheimer’s disease microbiome is associated with dysregulation of the anti-inflammatory p-glycoprotein pathway
Haran, J. P., Bhattarai, S. K., Foley, S. E., Dutta, P., Ward, D. V., Bucci, V., & McCormick, B. A. (2019) · mBio
Gut microbiota and healthAlzheimer's disease research and treatments
Cited by 412
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Neuronal Cell Death Mechanisms in Major Neurodegenerative Diseases
Chi, H., Chang, H.-Y., & Sang, T.-K. (2018) · International Journal of Molecular Sciences
Cell death mechanisms and regulationNeuroinflammation and Neurodegeneration Mechanisms
Cited by 412
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Natural selection interacts with recombination to shape the evolution of hybrid genomes
Schumer, M., Xu, C., Powell, D. L., Durvasula, A., Skov, L., Holland, C., Blazier, J. C., Sankararaman, S., Andolfatto, P., Rosenthal, G. G., et al. (2018) · Science
Evolution and Genetic DynamicsGenetic diversity and population structure
Cited by 412
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