Most cited biochemistry, genetics and molecular biology papers
- Verified
Microbial Genes in the Human Genome: Lateral Transfer or Gene Loss?
Salzberg, S. L., White, O., Peterson, J., & Eisen, J. A. (2001) · Science
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 326
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A minimal midzone protein module controls formation and length of antiparallel microtubule overlaps
Bieling, P., Telley, I. A., & Surrey, T. (2010) · Cell
Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics
Cited by 326
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Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing
Chandel, N. S., Jasper, H., Ho, T. T., & Passegué, E. (2016) · Nature Cell Biology
Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer
Cited by 326
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Mitochondria—Judges and Executioners of Cell Death Sentences
Bhola, P. D., & Letai, A. (2016) · Molecular Cell
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 326
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Targeted protein degradation: advances in drug discovery and clinical practice
Zhong, G., Chang, X., Xie, W., & Zhou, X. (2024) · Signal Transduction and Targeted Therapy
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 326
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Ducky Mouse Phenotype of Epilepsy and Ataxia Is Associated with Mutations in the Cacna2d2 Gene and Decreased Calcium Channel Current in Cerebellar Purkinje Cells
Barclay, J., Balaguero, N., Mione, M., Ackerman, S. L., Letts, V. A., Brodbeck, J., Canti, C., Meir, A., Page, K. M., Kusumi, K., et al. (2001) · The Journal of Neuroscience
Ion channel regulation and functionEpilepsy research and treatment
Cited by 326
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Mesenchymal stem cells induce apoptosis of activated T cells
Plumas, J., Chaperot, L., Richard, M.-J., Molens, J.-P., Bensa, J.-C., & Favrot, M.-C. (2005) · Leukemia
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 326
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Expression and function of IRS-1 in insulin signal transmission.
Sun, X. J., Miralpeix, M., Myers, M. G., Glasheen, E. M., Backer, J. M., Kahn, C. R., & White, M. F. (1992) · Journal of Biological Chemistry
Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling
Cited by 326
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A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders
Zufferey, F., Sherr, E. H., Beckmann, N. D., Hanson, E., Maillard, A. M., Hippolyte, L., Macé, A., Ferrari, C., Kutalik, Z., Andrieux, J., et al. (2012) · Journal of Medical Genetics
Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders
Cited by 326
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Lactate metabolism is associated with mammalian mitochondria
Chen, Y.-J., Mahieu, N. G., Huang, X., Singh, M., Crawford, P. A., Johnson, S. L., Gross, R. W., Schaefer, J., & Patti, G. J. (2016) · Nature Chemical Biology
Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology
Cited by 326
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Microbiota composition and metabolism are associated with gut function in Parkinson's disease
Cirstea, M. S., Yu, A. C., Golz, E., Sundvick, K., Kliger, D., Radisavljevic, N., Foulger, L. H., Mackenzie, M., Huan, T., Finlay, B. B., et al. (2020) · Movement Disorders
Gut microbiota and healthParkinson's Disease Mechanisms and Treatments
Cited by 326
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Adherence to the Mediterranean diet is associated with the gut microbiota pattern and gastrointestinal characteristics in an adult population
Mitsou, E. K., Kakali, A., Antonopoulou, S., Mountzouris, K. C., Yannakoulia, M., Panagiotakos, D. B., & Kyriacou, A. (2017) · British Journal of Nutrition
Gut microbiota and healthNutritional Studies and Diet
Cited by 325
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In Vivo HIF-Mediated Reductive Carboxylation Is Regulated by Citrate Levels and Sensitizes VHL-Deficient Cells to Glutamine Deprivation
Gameiro, P. A., Yang, J., Metelo, A. M., Pérez-Carro, R., Baker, R., Wang, Z., Arreola, A., Rathmell, W. K., Olumi, A., López-Larrubia, P., et al. (2013) · Cell Metabolism
Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism
Cited by 325
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Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells
Coffee, B., Zhang, F., Warren, S. T., & Reines, D. (1999) · Nature Genetics
Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation
Cited by 325
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AXL Mediates Resistance to PI3Kα Inhibition by Activating the EGFR/PKC/mTOR Axis in Head and Neck and Esophageal Squamous Cell Carcinomas
Elkabets, M., Pazarentzos, E., Juric, D., Sheng, Q., Pelossof, R. A., Brook, S., Benzaken, A. O., Rodon, J., Morse, N., Yan, J. J., et al. (2015) · Cancer Cell
PI3K/AKT/mTOR signaling in cancerLung Cancer Treatments and Mutations
Cited by 325
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A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear
Landegger, L. D., Pan, B., Askew, C., Wassmer, S. J., Gluck, S. D., Galvin, A., Taylor, R., Forge, A., Stankovic, K. M., Holt, J. R., et al. (2017) · Nature Biotechnology
Virus-based gene therapy researchHearing, Cochlea, Tinnitus, Genetics
Cited by 325
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Kremen2 modulates Dickkopf2 activity during Wnt/lRP6 signaling
Mao, B., & Niehrs, C. (2003) · Gene
Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation
Cited by 325
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Pim‐1 kinase promotes inactivation of the pro‐apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site
Aho, T. L. T., Sandholm, J., Peltola, K. J., Mankonen, H. P., Lilly, M., & Koskinen, P. J. (2004) · FEBS Letters
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 325
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Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma
Shi, Y., Lim, S. K., Liang, Q., Iyer, S. V., Wang, H.-Y., Wang, Z., Xie, X., Sun, D., Chen, Y.-J., Tabar, V., et al. (2019) · Nature
Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology
Cited by 325
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Decreased Muscle Glucose-Transport Phosphorylation Is an Early Defect in the Pathogenesis of Non-Insulin-Dependent Diabetes-Mellitus
Rothman, D. L., Magnusson, I., Cline, G., Gerard, D., Kahn, C. R., Shulman, R. G., & Shulman, G. I. (1995) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 325
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Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo.
Schneider, D. S., Hudson, K. L., Lin, T. Y., & Anderson, K. V. (1991) · Genes & Development
Developmental Biology and Gene RegulationImmune Response and Inflammation
Cited by 325
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High-efficiency prime editing with optimized, paired pegRNAs in plants
Lin, Q., Jin, S., Zong, Y., Yu, H., Zhu, Z., Liu, G., Kou, L., Wang, Y., Qiu, J.-L., Li, J., et al. (2021) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 325
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A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria.
Supek, F., Supekova, L., Nelson, H., & Nelson, N. (1996) · Proceedings of the National Academy of Sciences
Fungal and yeast genetics researchHeavy Metal Exposure and Toxicity
Cited by 325
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The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins
Chandra, A., Grecco, H. E., Pisupati, V., Perera, D., Cassidy, L., Skoulidis, F., Ismail, S. A., Hedberg, C., Hanzal-Bayer, M., Venkitaraman, A. R., et al. (2012) · Nature Cell Biology
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 325
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