Most cited biochemistry, genetics and molecular biology papers
- Verified
The Pentacovalent Phosphorus Intermediate of a Phosphoryl Transfer Reaction
Lahiri, S. D., Zhang, G., Dunaway-Mariano, D., & Allen, K. N. (2003) · Science
Enzyme Structure and FunctionPhysical Organic Chemistry and Reaction Kinetics
Cited by 325
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Elevated levels of tumor necrosis factor alpha and mortality in centenarians
Bruunsgaard, H., Andersen-Ranberg, K., Hjelmborg, J. V. B., Pedersen, B. K., & Jeune, B. (2003) · The American Journal of Medicine
Genetics, Aging, and Longevity in Model OrganismsInflammatory Biomarkers in Disease Prognosis
Cited by 325
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Nucleosomes are well positioned in exons and carry characteristic histone modifications
Andersson, R., Enroth, S., Rada-Iglesias, A., Wadelius, C., & Komorowski, J. (2009) · Genome Research
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 325
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Human pluripotent stem cell-derived neural constructs for predicting neural toxicity
Schwartz, M. P., Hou, Z., Propson, N. E., Zhang, J., Engstrom, C. J., Costa, V. S., Jiang, P., Nguyen, B. K., Bolin, J. M., Daly, W., et al. (2015) · Proceedings of the National Academy of Sciences
Pluripotent Stem Cells ResearchAnimal testing and alternatives
Cited by 325
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Recombination at Double-Strand Breaks and DNA Ends
Cromie, G. A., Connelly, J. C., & Leach, D. R. F. (2001) · Molecular Cell
DNA Repair MechanismsCRISPR and Genetic Engineering
Cited by 325
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Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary
Koike, H., Iwasawa, K., Ouchi, R., Maezawa, M., Giesbrecht, K., Saiki, N., Ferguson, A., Kimura, M., Thompson, W. L., Wells, J. M., et al. (2019) · Nature
Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation
Cited by 325
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The Role of miR‐21 in Cancer
Pfeffer, S. R., Yang, C. H., & Pfeffer, L. M. (2015) · Drug Development Research
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 325
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Detecting Liquid Remnants of Solid Tumors: Circulating Tumor DNA Minimal Residual Disease
Moding, E. J., Nabet, B. Y., Alizadeh, A. A., & Diehn, M. (2021) · Cancer Discovery
Cancer Genomics and DiagnosticsCancer Immunotherapy and Biomarkers
Cited by 325
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Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
Lee, S.-H., Cho, S.-Y., Yoon, Y., Park, C., Sohn, J., Jeong, J.-J., Jeon, B.-N., Jang, M., An, C., Lee, S., et al. (2021) · Nature Microbiology
Gut microbiota and healthCancer Immunotherapy and Biomarkers
Cited by 325
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The Role of Reactive Oxygen Species in Mitochondrial Permeability Transition
Vercesi, A. E., Kowaltowski, A. J., Grijalba, M. T., Meinicke, A. R., & Castilho, R. F. (1997) · Bioscience Reports
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 325
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Identification of specific PP2A complexes involved in human cell transformation
Chen, W., Possemato, R., Campbell, K. T., Plattner, C. A., Pallas, D. C., & Hahn, W. C. (2004) · Cancer Cell
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 325
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Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity
Choi, C. S., Savage, D. B., Abu-Elheiga, L., Liu, Z.-X., Kim, S., Kulkarni, A., Distefano, A., Hwang, Y.-J., Reznick, R. M., Codella, R., et al. (2007) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 325
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Parameter estimation and model selection in computational biology
Lillacci, G., & Khammash, M. (2010) · PLoS Computational Biology
Gene Regulatory Network AnalysisControl Systems and Identification
Cited by 325
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Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation
Peled, J. U., Devlin, S. M., Staffas, A., Lumish, M., Khanin, R., Littmann, E. R., Ling, L., Kosuri, S., Maloy, M., Slingerland, J. B., et al. (2017) · Journal of Clinical Oncology
Gut microbiota and healthHematopoietic Stem Cell Transplantation
Cited by 325
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Transcriptional coregulators in the control of energy homeostasis
Feige, J. N., & Auwerx, J. (2007) · Trends in Cell Biology
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 325
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The metabolic regulation of aging
Finkel, T. (2015) · Nature Medicine
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 325
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Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone
Episkopou, V, Maeda, S., Nishiguchi, S., Shimada, K., Gaitanaris, G. A., Gottesman, M. E., & Robertson, E. J. (1993) · Proceedings of the National Academy of Sciences
Retinoids in leukemia and cellular processesProtein Interaction Studies and Fluorescence Analysis
Cited by 325
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Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates
Foster, D. J., Brown, C. R., Shaikh, S., Trapp, C., Schlegel, M. K., Qian, K., Sehgal, A., Rajeev, K. G., Jadhav, V., Manoharan, M., et al. (2018) · Molecular Therapy
RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry
Cited by 325
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Telomere length in different tissues of elderly patients
Friedrich, U., Griese, E.-U., Schwab, M., Fritz, P., Thon, K.-P., & Klotz, U. (2000) · Mechanisms of Ageing and Development
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 325
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Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy
Bajaj, J. S., Betrapally, N. S., Hylemon, P. B., Heuman, D. M., Daita, K., White, M. B., Unser, A., Thacker, L. R., Sanyal, A. J., Kang, D. J., et al. (2015) · Hepatology
Gut microbiota and healthLiver Disease and Transplantation
Cited by 325
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Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA
Thompson, J. C., Yee, S. S., Troxel, A. B., Savitch, S. L., Fan, R., Balli, D., Lieberman, D. B., Morrissette, J. D., Evans, T. L., Bauml, J., et al. (2016) · Clinical Cancer Research
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 325
- Verified
Correlation of an epigenetic mitotic clock with cancer risk
Yang, Z., Wong, A., Kuh, D., Paul, D. S., Rakyan, V. K., Leslie, R. D., Zheng, S. C., Widschwendter, M., Beck, S., & Teschendorff, A. E. (2016) · Genome Biology
Epigenetics and DNA MethylationCancer Genomics and Diagnostics
Cited by 325
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High temporal and inter‐individual variation detected in the human ileal microbiota
Booijink, C. C. G. M., El‐Aidy, S., Rajilić‐Stojanović, M., Heilig, H. G. H. J., Troost, F. J., Smidt, H., Kleerebezem, M., De Vos, W. M., & Zoetendal, E. G. (2010) · Environmental Microbiology
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 324
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Gut microbiome, big data and machine learning to promote precision medicine for cancer
Cammarota, G., Ianiro, G., Ahern, A., Carbone, C., Temko, A., Claesson, M. J., Gasbarrini, A., & Tortora, G. (2020) · Nature Reviews Gastroenterology & Hepatology
Gut microbiota and healthColorectal Cancer Treatments and Studies
Cited by 324
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