Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency

Matharu, N., Rattanasopha, S., Tamura, S., Maliskova, L., Wang, Y., Bernard, A., Hardin, A., Eckalbar, W. L., Vaisse, C., & Ahituv, N. (2019) · Science

CRISPR and Genetic EngineeringRegulation of Appetite and Obesity

Cited by 323

Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis

Pernigoni, N., Zagato, E., Calcinotto, A., Troiani, M., Mestre, R. P., Calì, B., Attanasio, G., Troisi, J., Minini, M., Mosole, S., et al. (2021) · Science

Prostate Cancer Treatment and ResearchGut microbiota and health

Cited by 323

Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

Holland, C. H., Tanevski, J., Perales-Patón, J., Gleixner, J., Kumar, M. P., Mereu, E., Joughin, B. A., Stegle, O., Lauffenburger, D. A., Heyn, H., et al. (2020) · Genome Biology

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

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Towards population-scale long-read sequencing

De Coster, W., Weissensteiner, M. H., & Sedlazeck, F. J. (2021) · Nature Reviews Genetics

Genomics and Phylogenetic StudiesGenomic variations and chromosomal abnormalities

Cited by 323

The KAP1 Corepressor Functions To Coordinate the Assembly of De Novo HP1-Demarcated Microenvironments of Heterochromatin Required for KRAB Zinc Finger Protein-Mediated Transcriptional Repression

Sripathy, S. P., Stevens, J., & Schultz, D. C. (2006) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 323

The ABC transporter proteins Pat1 and Pat2 are required for import of long‐chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

Hettema, E. H., van Roermund, C. W., Distel, B., van den Berg, M., Vilela, C., Rodrigues‐Pousada, C., Wanders, R. J., & Tabak, H. F. (1996) · The EMBO Journal

Lipid metabolism and biosynthesisMetabolism and Genetic Disorders

Cited by 323

Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese mice

Zheng, X., Huang, F., Zhao, A., Lei, S., Zhang, Y., Xie, G., Chen, T., Qu, C., Rajani, C., Dong, B., et al. (2017) · BMC Biology

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 323

Mechanisms regulating skin pigmentation: The rise and fall of complexion coloration

Ebanks, J. P., Wickett, R. R., & Boissy, R. E. (2009) · International Journal of Molecular Sciences

melanin and skin pigmentationMelanoma and MAPK Pathways

Cited by 323

STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death

Wu, J., Chen, Y.-J., Dobbs, N., Sakai, T., Liou, J., Miner, J. J., & Yan, N. (2019) · Journal of Experimental Medicine

Endoplasmic Reticulum Stress and Diseaseinterferon and immune responses

Cited by 323

Single-cell transcriptional profiles in human skeletal muscle

Rubenstein, A. B., Smith, G. R., Raue, U., Begue, G., Minchev, K., Ruf-Zamojski, F., Nair, V. D., Wang, X., Zhou, L., Zaslavsky, E., et al. (2020) · Scientific Reports

Single-cell and spatial transcriptomicsMuscle Physiology and Disorders

Cited by 323

Core Fucosylation Regulates Epidermal Growth Factor Receptor-mediated Intracellular Signaling

Wang, X., Gu, J., Ihara, H., Miyoshi, E., Honke, K., & Taniguchi, N. (2006) · Journal of Biological Chemistry

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 323

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence.

Sadaie, M., Salama, R., Carroll, T., Tomimatsu, K., Chandra, T., Young, A. R. J., Narita, M., Pérez-Mancera, P. A., Bennett, D. C., Chong, H., et al. (2013) · Genes & Development

Nuclear Structure and FunctionTelomeres, Telomerase, and Senescence

Cited by 323

DNA repair deficiency and neurological disease

McKinnon, P. J. (2009) · Nature Reviews Neuroscience

DNA Repair MechanismsGenetics and Neurodevelopmental Disorders

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mRNA helicases: the tacticians of translational control

Parsyan, A., Svitkin, Y., Shahbazian, D., Gkogkas, C., Lasko, P., Merrick, W. C., & Sonenberg, N. (2011) · Nature Reviews Molecular Cell Biology

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 323

Horizontal gene transfer in fungi

Fitzpatrick, D. A. (2012) · FEMS Microbiology Letters

Fungal and yeast genetics researchGenomics and Phylogenetic Studies

Cited by 323

What's in a genome? The C-value enigma and the evolution of eukaryotic genome content

Elliott, T. A., & Gregory, T. R. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences

Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies

Cited by 323

Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis

Chen, Y., Gelfond, J. A., McManus, L. M., & Shireman, P. K. (2009) · BMC Genomics

Molecular Biology Techniques and ApplicationsMicroRNA in disease regulation

Cited by 323

Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore

Leung, A. W. C., & Halestrap, A. P. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 323

Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone

Xiong, J., Piemontese, M., Onal, M., Campbell, J., Goellner, J. J., Dusevich, V., Bonewald, L., Manolagas, S. C., & O’Brien, C. A. (2015) · PLOS ONE

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 323

Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP.

Arora, K. K., & Pedersen, P. L. (1988) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 323

Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism

Schell, J. C., Wisidagama, D. R., Bensard, C., Zhao, H., Wei, P., Tanner, J., Flores, A., Mohlman, J., Sorensen, L. K., Earl, C. S., et al. (2017) · Nature Cell Biology

Metabolism, Diabetes, and CancerCancer, Hypoxia, and Metabolism

Cited by 322

Real time monitoring of multiple parameters in mammalian cell culture bioreactors using an in-line Raman spectroscopy probe

Abu‐Absi, N. R., Kenty, B. M., Cuellar, M. E., Borys, M. C., Sakhamuri, S., Strachan, D. J., Hausladen, M. C., & Li, Z. J. (2011) · Biotechnology and Bioengineering

Spectroscopy Techniques in Biomedical and Chemical ResearchViral Infectious Diseases and Gene Expression in Insects

Cited by 322

JNK signaling in cancer cell survival

Wu, Q., Wu, W., Fu, B., Shi, L., Wang, X., & Kuca, K. (2019) · Medicinal Research Reviews

NF-κB Signaling PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 322

Depolymerization of β-1,6-N-Acetyl-d-Glucosamine Disrupts the Integrity of Diverse Bacterial Biofilms

Itoh, Y., Wang, X., Hinnebusch, B. J., Preston, J. F., & Romeo, T. (2005) · Journal of Bacteriology

Bacterial biofilms and quorum sensingPolysaccharides Composition and Applications

Cited by 322