Most cited biochemistry, genetics and molecular biology papers
- Verified
Crystal structure of a Rad51 filament
Conway, A. B., Lynch, T. W., Zhang, Y., Fortin, G. S., Fung, C. W., Symington, L. S., & Rice, P. A. (2004) · Nature Structural & Molecular Biology
DNA Repair MechanismsEnzyme Structure and Function
Cited by 310
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Genetics and regulation of two distinct haem-uptake systems, phu and has, in Pseudomonas aeruginosa The GenBank accession numbers for the sequences reported in this paper are AF055999, AF127222, and AF127223.
Ochsner, U. A., Johnson, Z., & Vasil, M. L. (2000) · Microbiology
Bacterial Genetics and BiotechnologyIron Metabolism and Disorders
Cited by 310
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Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases
Chen, R., Shi, L., Hakenberg, J., Naughton, B., Sklar, P., Zhang, J., Zhou, H., Tian, L., Prakash, O., Lemire, M., et al. (2016) · Nature Biotechnology
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 310
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miR‐23a‐3p‐abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration
Hu, H., Dong, L., Bu, Z., Shen, Y., Luo, J., Zhang, H., Zhao, S., Lv, F., & Liu, Z. (2020) · Journal of Extracellular Vesicles
Extracellular vesicles in diseaseOsteoarthritis Treatment and Mechanisms
Cited by 310
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Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
Ubeda, C., Lipuma, L., Gobourne, A., Viale, A., Leiner, I., Equinda, M., Khanin, R., & Pamer, E. G. (2012) · Journal of Experimental Medicine
Gut microbiota and healthImmune Response and Inflammation
Cited by 310
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Stepwise engineering to produce high yields of very long-chain polyunsaturated fatty acids in plants
Wu, G., Truksa, M., Datla, N., Vrinten, P., Bauer, J., Zank, T., Cirpus, P., Heinz, E., & Qiu, X. (2005) · Nature Biotechnology
Lipid metabolism and biosynthesisPlant biochemistry and biosynthesis
Cited by 310
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Constitutive Nuclear Factor-κB Activity Is Required for Central Neuron Survival
Bhakar, A. L., Tannis, L.-L., Zeindler, C., Russo, M. P., Jobin, C., Park, D. S., MacPherson, S., & Barker, P. A. (2002) · The Journal of Neuroscience
NF-κB Signaling PathwaysNuclear Receptors and Signaling
Cited by 310
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Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC
Thomas, L. R., Wang, Q., Grieb, B. C., Phan, J., Foshage, A. M., Sun, Q., Olejniczak, E. T., Clark, T., Dey, S., Lorey, S., et al. (2015) · Molecular Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 310
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Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses
Maroto, R., Zhao, Y., Jamaluddin, M., Popov, V. L., Wang, H., Kalubowilage, M., Zhang, Y., Luisi, J., Sun, H., Culbertson, C. T., et al. (2017) · Journal of Extracellular Vesicles
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 310
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Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation
Chidlow, J. H., & Sessa, W. C. (2010) · Cardiovascular Research
Caveolin-1 and cellular processesExtracellular vesicles in disease
Cited by 310
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Ubiquitination of RIP1 Regulates an NF-κB-Independent Cell-Death Switch in TNF Signaling
O'Donnell, M. A., Legarda-Addison, D., Skountzos, P., Yeh, W. C., & Ting, A. T. (2007) · Current Biology
NF-κB Signaling PathwaysCell death mechanisms and regulation
Cited by 310
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Mapping and characterization of structural variation in 17,795 human genomes
Genomics, N. C. F. C. D., Abel, H. J., Larson, D. E., Regier, A. A., Chiang, C., Das, I., Kanchi, K. L., Layer, R. M., Neale, B. M., Salerno, W. J., et al. (2020) · Nature
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 310
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BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX
Gavathiotis, E., Reyna, D. E., Davis, M. L., Bird, G. H., & Walensky, L. D. (2010) · Molecular Cell
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 310
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Identification and Characterization of Ral-Binding Protein 1, a Potential Downstream Target of Ral GTPases
Cantor, S. B., Urano, T., & Feig, L. A. (1995) · Molecular and Cellular Biology
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 310
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Wnt-5A/Ror2 Regulate Expression of XPAPC through an Alternative Noncanonical Signaling Pathway
Schambony, A., & Wedlich, D. (2007) · Developmental Cell
Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation
Cited by 310
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SUBACUTE SPONGIFORM ENCEPHALOPATHY (CREUTZFELDT-JAKOB DISEASE): THE NATURE AND PROGRESSION OF SPONGIFORM CHANGE
MASTERS, C. L., & RICHARDSON, E. P. (1978) · Brain
Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments
Cited by 310
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C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization
Timpson, N. J., Nordestgaard, B. G., Harbord, R. M., Zacho, J., Frayling, T. M., Tybjærg-Hansen, A., & Davey Smith, G. (2011) · International Journal of Obesity
Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases
Cited by 310
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Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms
Jura, N., Zhang, X., Endres, N. F., Seeliger, M. A., Schindler, T., & Kuriyan, J. (2011) · Molecular Cell
Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics
Cited by 310
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Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway
Lu, M., Liu, T., Jiao, Q., Ji, J., Tao, M., Liu, Y., You, Q., & Jiang, Z. (2018) · European Journal of Medicinal Chemistry
Protein Degradation and InhibitorsAlzheimer's disease research and treatments
Cited by 310
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Gut Microbiota-Dependent Modulation of Energy Metabolism
Heiss, C. N., & Olofsson, L. E. (2018) · Journal of Innate Immunity
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 310
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Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity
Clark, S. J., Lee, H. J., Smallwood, S. A., Kelsey, G., & Reik, W. (2016) · Genome Biology
Single-cell and spatial transcriptomicsEpigenetics and DNA Methylation
Cited by 310
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The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18
Jha, S., Srivastava, S. Y., Brickey, W. J., Iocca, H., Toews, A., Morrison, J. P., Chen, V. S., Gris, D., Matsushima, G. K., & Ting, J. P.-Y. (2010) · The Journal of Neuroscience
Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms
Cited by 310
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From SOMAmer-based biomarker discovery to diagnostic and clinical applications: a SOMAmer-based, streamlined multiplex proteomic assay
Kraemer, S., Vaught, J. D., Bock, C., Gold, L., Katilius, E., Keeney, T. R., Kim, N., Saccomano, N. A., Wilcox, S. K., Zichi, D., et al. (2011) · PLoS ONE
Advanced Biosensing Techniques and ApplicationsAdvanced Proteomics Techniques and Applications
Cited by 310
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A reference human induced pluripotent stem cell line for large-scale collaborative studies
Pantazis, C. B., Yang, A., Lara, E., McDonough, J. A., Blauwendraat, C., Peng, L., Oguro, H., Kanaujiya, J., Zou, J., Sebesta, D., et al. (2022) · Cell Stem Cell
Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering
Cited by 310
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