Most cited biochemistry, genetics and molecular biology papers
- Verified
Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms
Alter, O., Brown, P. O., & Botstein, D. (2003) · Proceedings of the National Academy of Sciences
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 304
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Trimethylamine‐N‐oxide promotes brain aging and cognitive impairment in mice
Li, D., Ke, Y., Zhan, R., Liu, C., Zhao, M., Zeng, A., Shi, X., Ji, L., Cheng, S., Pan, B., et al. (2018) · Aging Cell
Genetics, Aging, and Longevity in Model OrganismsAntioxidants, Aging, Portulaca oleracea
Cited by 304
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The unusual amino acid L-ergothioneine is a physiologic cytoprotectant
Paul, B. D., & Snyder, S. H. (2010) · Cell Death & Differentiation
Sulfur Compounds in BiologyRedox biology and oxidative stress
Cited by 304
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Cell fate control by pioneer transcription factors
Iwafuchi-Doi, M., & Zaret, K. S. (2016) · Development
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 304
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Early-life experience, epigenetics, and the developing brain
Kundakovic, M., & Champagne, F. A. (2015) · Neuropsychopharmacology
Epigenetics and DNA MethylationChild Abuse and Trauma
Cited by 304
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Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei
Ren, J., Isakova, A., Friedmann, D., Zeng, J., Grutzner, S. M., Pun, A., Zhao, G. Q., Kolluru, S. S., Wang, R., Lin, R., et al. (2019) · eLife
Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research
Cited by 304
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TRANSLATIONAL ACCURACY AND THE FITNESS OF BACTERIA
Kurland, C. G. (1992) · Annual Review of Genetics
RNA and protein synthesis mechanismsEvolution and Genetic Dynamics
Cited by 304
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Differential Control of Clustering of the Sodium Channels Nav1.2 and Nav1.6 at Developing CNS Nodes of Ranvier
Kaplan, M. R., Cho, M.-H., Ullian, E. M., Isom, L. L., Levinson, S. R., & Barres, B. A. (2001) · Neuron
Ion channel regulation and functionIon Transport and Channel Regulation
Cited by 304
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The relationship between genome structure and function
Oudelaar, A. M., & Higgs, D. R. (2021) · Nature Reviews Genetics
Genomics and Chromatin DynamicsChromosomal and Genetic Variations
Cited by 304
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Werner and Hutchinson–Gilford progeria syndromes: mechanistic basis of human progeroid diseases
Kudlow, B. A., Kennedy, B. K., & Monnat, R. J. (2007) · Nature Reviews Molecular Cell Biology
Nuclear Structure and FunctionTelomeres, Telomerase, and Senescence
Cited by 304
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Replication timing-related and gene body-specific methylation of active human genes
Aran, D., Toperoff, G., Rosenberg, M., & Hellman, A. (2011) · Human Molecular Genetics
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 304
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Analysis of combinatorial cis-regulation in synthetic and genomic promoters
Gertz, J., Siggia, E. D., & Cohen, B. A. (2009) · Nature
Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics
Cited by 304
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Identification of Sef, a novel modulator of FGF signalling
Tsang, M., Friesel, R., Kudoh, T., & Dawid, I. B. (2002) · Nature Cell Biology
Fibroblast Growth Factor ResearchDevelopmental Biology and Gene Regulation
Cited by 304
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Integrated Model of De Novo and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes
He, X., Sanders, S. J., Liu, L., De Rubeis, S., Lim, E. T., Sutcliffe, J. S., Schellenberg, G. D., Gibbs, R. A., Daly, M. J., Buxbaum, J. D., et al. (2013) · PLoS Genetics
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 304
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The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes
Gillespie, K. M., Bain, S. C., Barnett, A. H., Bingley, P. J., Christie, M. R., Gill, G. V., & Gale, E. A. (2004) · The Lancet
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 304
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Gut microbiota diversity across ethnicities in the United States
Brooks, A. W., Priya, S., Blekhman, R., & Bordenstein, S. R. (2018) · PLOS Biology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 304
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Interpreting steep dose-response curves in early inhibitor discovery.
Shoichet, B. K. (2006) · Journal of Medicinal Chemistry
Enzyme function and inhibitionComputational Drug Discovery Methods
Cited by 304
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Crystal Structure of Epoxomicin:20S Proteasome Reveals a Molecular Basis for Selectivity of α‘,β‘-Epoxyketone Proteasome Inhibitors
Groll, M., Kim, K. B., Kairies, N., Huber, R., & Crews, C. M. (2000) · Journal of the American Chemical Society
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 304
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The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition
Cloonan, N., Brown, M. K., Steptoe, A. L., Wani, S., Chan, W. L., Forrest, A. R., Kolle, G., Gabrielli, B., & Grimmond, S. M. (2008) · Genome Biology
MicroRNA in disease regulationCancer-related Molecular Pathways
Cited by 304
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Depth Penetration and Detection of pH Gradients in Biofilms by Two-Photon Excitation Microscopy
Vroom, J. M., De Grauw, K. J., Gerritsen, H. C., Bradshaw, D. J., Marsh, P. D., Watson, G. K., Birmingham, J. J., & Allison, C. (1999) · Applied and Environmental Microbiology
Bacterial biofilms and quorum sensingAdvanced Fluorescence Microscopy Techniques
Cited by 303
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Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA
Schousboe, A., Bak, L. K., & Waagepetersen, H. S. (2013) · Frontiers in Endocrinology
Amino Acid Enzymes and MetabolismNeuroscience and Neuropharmacology Research
Cited by 303
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Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy
Sinha, R. A., You, S.-H., Zhou, J., Siddique, M. M., Bay, B.-H., Zhu, X., Privalsky, M. L., Cheng, S.-Y., Stevens, R. D., Summers, S. A., et al. (2012) · Journal of Clinical Investigation
Autophagy in Disease and TherapyThyroid Disorders and Treatments
Cited by 303
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Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity
González‐Gualda, E., Pàez‐Ribes, M., Lozano‐Torres, B., Macias, D., Wilson, J. R., González‐López, C., Ou, H., Mirón‐Barroso, S., Zhang, Z., Lérida‐Viso, A., et al. (2020) · Aging Cell
Telomeres, Telomerase, and SenescenceNanoparticle-Based Drug Delivery
Cited by 303
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Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: Molecular diversity and associated phenotypic spectrum
Sarkozy, A., Carta, C., Moretti, S., Zampino, G., Digilio, M. C., Pantaleoni, F., Scioletti, A. P., Esposito, G., Cordeddu, V., Lepri, F., et al. (2009) · Human Mutation
Protein Tyrosine PhosphatasesGenomics and Rare Diseases
Cited by 303
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