Most cited biochemistry, genetics and molecular biology papers
- Verified
Exome Sequencing and the Management of Neurometabolic Disorders
Tarailo-Graovac, M., Shyr, C., Ross, C. J., Horvath, G. A., Salvarinova, R., Ye, X. C., Zhang, L.-H., Bhavsar, A. P., Lee, J. J. Y., Drögemöller, B. I., et al. (2016) · New England Journal of Medicine
Metabolism and Genetic DisordersGenomics and Rare Diseases
Cited by 281
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Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators
Duffney, L. J., Zhong, P., Wei, J., Matas, E., Cheng, J., Qin, L., Ma, K., Dietz, D. M., Kajiwara, Y., Buxbaum, J. D., et al. (2015) · Cell Reports
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 281
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Estimating the mutation load in human genomes
Henn, B. M., Botigué, L. R., Bustamante, C. D., Clark, A. G., & Gravel, S. (2015) · Nature Reviews Genetics
Evolution and Genetic DynamicsGenomics and Rare Diseases
Cited by 281
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Allostery: An Overview of Its History, Concepts, Methods, and Applications
Liu, J., & Nussinov, R. (2016) · PLOS Computational Biology
Protein Structure and DynamicsReceptor Mechanisms and Signaling
Cited by 281
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Fumarate induces redox-dependent senescence by modifying glutathione metabolism
Zheng, L., Cardaci, S., Jerby, L., MacKenzie, E. D., Sciacovelli, M., Johnson, T. I., Gaude, E., King, A., Leach, J. D. G., Edrada-Ebel, R., et al. (2015) · Nature Communications
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress
Cited by 281
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State-of-the-Art Estimation of Protein Model Accuracy Using AlphaFold
Roney, J. P., & Ovchinnikov, S. (2022) · Physical Review Letters
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 281
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Hints of hidden heritability in GWAS
Gibson, G. (2010) · Nature Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 281
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A new era in functional genomics screens
Przybyla, L., & Gilbert, L. A. (2022) · Nature Reviews Genetics
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 281
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Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate
Lin, Y. C., Benner, C., Mansson, R., Heinz, S., Miyazaki, K., Miyazaki, M., Chandra, V., Bossen, C., Glass, C. K., & Murre, C. (2012) · Nature Immunology
Genomics and Chromatin DynamicsT-cell and B-cell Immunology
Cited by 281
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A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans
Lee, I., Lehner, B., Crombie, C., Wong, W., Fraser, A. G., & Marcotte, E. M. (2008) · Nature Genetics
Bioinformatics and Genomic NetworksGene Regulatory Network Analysis
Cited by 281
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Dietary intervention in infancy and later signs of beta-cell autoimmunity
Knip, M., Virtanen, S. M., Seppä, K., Ilonen, J., Savilahti, E., Vaarala, O., Reunanen, A., Teramo, K., Hämäläinen, A.-M., Paronen, J., et al. (2010) · New England Journal of Medicine
Diabetes and associated disordersInfant Nutrition and Health
Cited by 281
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Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity
Fonseca, D. M. D., Hand, T. W., Han, S.-J., Gerner, M. Y., Zaretsky, A. G., Byrd, A. L., Harrison, O. J., Ortiz, A. M., Quinones, M., Trinchieri, G., et al. (2015) · Cell
Gut microbiota and healthImmune Response and Inflammation
Cited by 281
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Role of DNA Methylation in Modulating Transcription Factor Occupancy
Maurano, M. T., Wang, H., John, S., Shafer, A., Canfield, T., Lee, K., & Stamatoyannopoulos, J. A. (2015) · Cell Reports
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 281
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Heme as key regulator of major mammalian cellular functions: Molecular, cellular, and pharmacological aspects
Tsiftsoglou, A. S., Tsamadou, A. I., & Papadopoulou, L. C. (2006) · Pharmacology & Therapeutics
Porphyrin Metabolism and DisordersHeme Oxygenase-1 and Carbon Monoxide
Cited by 281
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LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling
Ito, A., Hong, C., Rong, X., Zhu, X., Tarling, E. J., Hedde, P. N., Gratton, E., Parks, J., & Tontonoz, P. (2015) · eLife
Cholesterol and Lipid MetabolismImmune Response and Inflammation
Cited by 281
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Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans
Dantas, A., Day, A., Ikeh, M., Kos, I., Achan, B., & Quinn, J. (2015) · Biomolecules
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 281
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The prenatal origins of cancer
Marshall, G. M., Carter, D. R., Cheung, B. B., Liu, T., Mateos, M. K., Meyerowitz, J. G., & Weiss, W. A. (2014) · Nature Reviews Cancer
Cancer Genomics and DiagnosticsAcute Lymphoblastic Leukemia research
Cited by 281
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Aspects of high hydrostatic pressure food processing: Perspectives on technology and food safety
Aganovic, K., Hertel, C., Vogel, R. F., Johne, R., Schlüter, O., Schwarzenbolz, U., Jäger, H., Holzhauser, T., Bergmair, J., Roth, A., et al. (2021) · Comprehensive Reviews in Food Science and Food Safety
Microbial Inactivation MethodsListeria monocytogenes in Food Safety
Cited by 281
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Genome-wide characterization of mammalian promoters with distal enhancer functions
Dao, L. T. M., Galindo-Albarrán, A. O., Castro-Mondragon, J. A., Andrieu-Soler, C., Medina-Rivera, A., Souaid, C., Charbonnier, G., Griffon, A., Vanhille, L., Stephen, T., et al. (2017) · Nature Genetics
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 281
- Verified
Theory of lethal mutagenesis for viruses
Bull, J. J., Sanjuán, R., & Wilke, C. O. (2007) · Journal of Virology
Evolution and Genetic DynamicsMathematical and Theoretical Epidemiology and Ecology Models
Cited by 281
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Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression
Qin, C., Hu, Y., Zhou, B., Fernandez-Salas, E., Yang, C.-Y., Liu, L., McEachern, D., Przybranowski, S., Wang, M., Stuckey, J., et al. (2018) · Journal of Medicinal Chemistry
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 281
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The need for transparency and good practices in the qPCR literature
Bustin, S. A., Benes, V., Garson, J., Hellemans, J., Huggett, J., Kubista, M., Mueller, R., Nolan, T., Pfaffl, M. W., Shipley, G., et al. (2013) · Nature Methods
Molecular Biology Techniques and ApplicationsMeta-analysis and systematic reviews
Cited by 281
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Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strength.
KOSTENUIK, P. (2005) · Current Opinion in Pharmacology
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 281
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Posttranslational modifications of tubulin and the polarized transport of kinesin-1 in neurons
Hammond, J. W., Huang, C.-F., Kaech, S., Jacobson, C., Banker, G., & Verhey, K. J. (2010) · Molecular Biology of the Cell
Microtubule and mitosis dynamicsAxon Guidance and Neuronal Signaling
Cited by 281
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