Most cited biochemistry, genetics and molecular biology papers
- Verified
Roles of K + channels in regulating tumour cell proliferation and apoptosis
Wang, Z. (2004) · Pfl�gers Archiv European Journal of Physiology
Ion channel regulation and functionCell death mechanisms and regulation
Cited by 280
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Oral administration of rac-α-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial
Jacob, S., Ruus, P., Hermann, R., Tritschler, H. J., Maerker, E., Renn, W., Augustin, H. J., Dietze, G. J., & Rett, K. (1999) · Free Radical Biology and Medicine
Biochemical Acid Research StudiesNatural Antidiabetic Agents Studies
Cited by 280
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Improving CRISPR-Cas specificity with chemical modifications in single-guide RNAs
Ryan, D. E., Taussig, D., Steinfeld, I., Phadnis, S. M., Lunstad, B. D., Singh, M., Vuong, X., Okochi, K. D., McCaffrey, R., Olesiak, M., et al. (2018) · Nucleic Acids Research
CRISPR and Genetic EngineeringRNA Interference and Gene Delivery
Cited by 280
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Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells
Wei, P.-C., Chang, A. N., Kao, J., Du, Z., Meyers, R. M., Alt, F. W., & Schwer, B. (2016) · Cell
DNA Repair MechanismsGenomic variations and chromosomal abnormalities
Cited by 280
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A heterochromatin-dependent transcription machinery drives piRNA expression
Andersen, P. R., Tirian, L., Vunjak, M., & Brennecke, J. (2017) · Nature
Genomics and Chromatin DynamicsChromosomal and Genetic Variations
Cited by 280
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Structure of the Cand1-Cul1-Roc1 Complex Reveals Regulatory Mechanisms for the Assembly of the Multisubunit Cullin-Dependent Ubiquitin Ligases
Goldenberg, S. J., Cascio, T. C., Shumway, S. D., Garbutt, K. C., Liu, J., Xiong, Y., & Zheng, N. (2004) · Cell
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 280
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IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism
Grassian, A. R., Parker, S. J., Davidson, S. M., Divakaruni, A. S., Green, C. R., Zhang, X., Slocum, K. L., Pu, M., Lin, F., Vickers, C., et al. (2014) · Cancer Research
Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism
Cited by 280
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Energy expenditure and aging
Manini, T. M. (2010) · Ageing Research Reviews
Genetics, Aging, and Longevity in Model OrganismsRegulation of Appetite and Obesity
Cited by 280
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l -2-Hydroxyglutarate: An Epigenetic Modifier and Putative Oncometabolite in Renal Cancer
Shim, E.-H., Livi, C. B., Rakheja, D., Tan, J., Benson, D., Parekh, V., Kho, E.-Y., Ghosh, A. P., Kirkman, R., Velu, S., et al. (2014) · Cancer Discovery
Cancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation
Cited by 280
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Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria
Dai, D., Chen, T., Wanagat, J., Laflamme, M., Marcinek, D. J., Emond, M. J., Ngo, C. P., Prolla, T. A., & Rabinovitch, P. S. (2010) · Aging Cell
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 280
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Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants
Park, J.-H., Gail, M. H., Weinberg, C. R., Carroll, R. J., Chung, C. C., Wang, Z., Chanock, S. J., Fraumeni, J. F., & Chatterjee, N. (2011) · Proceedings of the National Academy of Sciences
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 280
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Myf5-Positive Satellite Cells Contribute to Pax7-Dependent Long-Term Maintenance of Adult Muscle Stem Cells
Günther, S., Kim, J., Kostin, S., Lepper, C., Fan, C.-M., & Braun, T. (2013) · Cell Stem Cell
Muscle Physiology and DisordersCongenital heart defects research
Cited by 280
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Solo: Doublet Identification in Single-Cell RNA-Seq via Semi-Supervised Deep Learning
Bernstein, N. J., Fong, N. L., Lam, I., Roy, M. A., Hendrickson, D. G., & Kelley, D. R. (2020) · Cell Systems
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 280
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Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells
Nalapareddy, K., Nattamai, K. J., Kumar, R. S., Karns, R., Wikenheiser-Brokamp, K. A., Sampson, L. L., Mahe, M. M., Sundaram, N., Yacyshyn, M.-B., Yacyshyn, B., et al. (2017) · Cell Reports
Wnt/β-catenin signaling in development and cancerGenetics, Aging, and Longevity in Model Organisms
Cited by 280
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Regulation of TNF-Induced Osteoclast Differentiation
Yao, Z., Getting, S. J., & Locke, I. C. (2021) · Cells
Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies
Cited by 280
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Repurposing drugs in oncology (ReDO)—Cimetidine as an anti-cancer agent
Pantziarka, P. (2014) · ecancermedicalscience
Cancer, Stress, Anesthesia, and Immune ResponseCancer Mechanisms and Therapy
Cited by 280
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Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
Zewinger, S., Reiser, J., Jankowski, V., Alansary, D., Hahm, E., Triem, S., Klug, M., Schunk, S. J., Schmit, D., Kramann, R., et al. (2020) · Nature Immunology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 280
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The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2
Stevenson, L. F., Sparks, A., Allende‐Vega, N., Xirodimas, D. P., Lane, D. P., & Saville, M. K. (2007) · The EMBO Journal
Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways
Cited by 280
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The Elusive P2X7 Macropore
Di Virgilio, F., Schmalzing, G., & Markwardt, F. (2018) · Trends in Cell Biology
Adenosine and Purinergic SignalingCalcium signaling and nucleotide metabolism
Cited by 279
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Autophagy is an immediate macrophage response to Legionella pneumophila
Amer, A. O., & Swanson, M. S. (2005) · Cellular Microbiology
Autophagy in Disease and TherapyLegionella and Acanthamoeba research
Cited by 279
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Isolation of lysozyme from egg white
Alderton, G., Ward, W. H., & Fevold, H. L. (1945) · Journal of Biological Chemistry
Protein purification and stabilityEnzyme Production and Characterization
Cited by 279
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Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping
Morgan, S. L., Mariano, N. C., Bermudez, A., Arruda, N. L., Wu, F., Luo, Y., Shankar, G., Jia, L., Chen, H., Hu, J.-F., et al. (2017) · Nature Communications
CRISPR and Genetic EngineeringGenomics and Chromatin Dynamics
Cited by 279
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As a Matter of Fat
Brookheart, R. T., Michel, C. I., & Schaffer, J. E. (2009) · Cell Metabolism
Lipid metabolism and biosynthesisCancer, Lipids, and Metabolism
Cited by 279
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Waste disposal—An attractive strategy for cancer therapy
Salami, J., & Crews, C. M. (2017) · Science
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 279
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